Metódy v genetike človeka a molekulovej biológii

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Tatiana Kimáková - Vladimír Pavlík

The scientific monograph focuses on the characteristics of free radicals, reactive oxygen and nitrogen species, oxidative stress, and its impact on various diseases. A significant portion is dedicated to antioxidants, their classification based on multiple criteria, the characteristics of selected antioxidants in terms of their functions, manifestations of their deficiency and excess, and the overall antioxidant capacity of the body.

A special section is devoted to enzyme-based antioxidants, natural sources of antioxidants in the form of vitamins, trace elements, flavonoids, polyphenols, and coenzyme Q10. To provide a clearer understanding of antioxidants and their influence on population health, the monograph presents results from a research project included in the program "Research Support for Enhancing the Defense Capabilities of the Czech Republic in NATO Structures."

The research was conducted between 2010 and 2012 as part of preventive rehabilitation programs for professional soldiers with a sports component. The study involved 218 professional soldiers, including 180 men and 38 women, with an average age of 33.3 years. The current health status and dietary habits of the soldiers were assessed using questionnaires.

The study described the saturation of the observed group with antioxidant vitamins and statistically evaluated the relationship between their levels and the risk indicators for the development of cardiovascular diseases. Individual analyses were performed using the Reflotron device calibrated with Reflotron Precinorm control serum. Following blood collection, all participants underwent anthropometric examinations (body weight, height, waist circumference), blood pressure measurements, heart rate monitoring, and physical fitness assessments through simple functional tests.

This scientific monograph is suitable for the scientific community, students of medical, veterinary, and natural sciences, as well as public health students at all levels of university education. It is also intended for informed members of the public.

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I. R. Mavlyanov - A. K. Ashirmetov - Z. I. Mavlyanov - G. J. Jarilkasinova

Need of carrying out a pharmacological genotyping for providing the individualized pharmacotherapy is shown in the monograph based on the analysis of own and literary data of the central link of drug pharmacokinetics– systems of cytochrome P-450, taking into account its genetic polymorphysm.
The monograph is intended for the clinical pharmacologists, geneticists and experts dealing with this problem.

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Ivana Skoumalová - Zuzana Dankulincová

The publication entitled Competencies for clinical practice in the field of communication with the patient serves as the background and teaching material.

The text is structured to bring theoretical knowledge about the topic, current research findings in the field and practical tips for training skills in practice. It provides clear information on individual parts of the training and is designed to acquire knowledge that is the basis for practical skills in medical communication, especially in communication with patients.

It is intended for general and dental students to deepen their knowledge and acquire missing skills in medical communication, which are evidence-based and research-validated skills that have a demonstrable positive impact on patient communication.

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Peter Olexa

Učebné texty „Vybrané kapitoly z gerontológie a geriatrie" sú určené pre štúdium študentov medicíny na Lekárskej fakulty UPJŠ v odbore Všeobecné lekárstvo v rámci výučby klinických špecializačných blokov v odbore Interná medicína - Geriatria .

Vo svojom úvode sa učebné texty venujú demografii z pohľadu starnutia populácie, vysvetľujú základné pojmy ako gerontológia, jej rozdelenie a následne sa zaoberajú aj úlohou a poslaním klinického odboru geriatria. Následne zrozumiteľne opisujú a vysvetľujú základné piliere geriatrickej medicíny, ktorými sú komplexné geriatrické vyšetrenie, základné geriatrické syndrómy, kam patrí krehkosť, malnutrícia, sarkopénia, kognitívne poruchy, a polyfarmácia . V závere sa venujú ageizmu, ktorý je tiež dôležitým javom v dnešnej klinickej medicíne.

MUDr. Peter Olexa, PhD.

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