Metódy v genetike človeka a molekulovej biológii

E-publikácia

Dorota Sopková

Forensic Medicine is a medical discipline that is concerned with determination of the cause of death in cases violent and non-violent deaths by performing an autopsy. It is based on morphological findings, which characterize the effects of various forms of violence, as well as pathological changes in various diseases. The presented textbook provides comprehensive and complete overview of the fundamental tasks and theoretical knowledge of the field of forensic medicine. Its aim is to provide a theoretical basis in the form of images of morphological autopsy findings for the study of the compulsory subject Forensic Medicine and Medical Law in the study programs General Medicine and Dentistry. The author emphasizes the necessity to understand the fundamentals of forensic medicine in every medical field and a multidisciplinary approach in clarifying medico-legal issues.

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E-book

Martina Čižmáriková - Peter Takáč 

It is known that pharmacology is a rapidly evolving medical field, with information about drug forms and their routes of administration constantly changing. In addition to the emergence of new drug forms, new trends are also observed in the routes of administration suitable for delivering drugs. Despite being significant factors influencing the efficacy and safety of pharmacotherapy – an indispensable component of comprehensive patient care – to our knowledge, there has been a lack of comprehensive and detailed textual material focused on this issue on the market. This fact is related to the broader scope of the professional text we are presenting, as rare drug forms or less commonly used routes of administration are only marginally mentioned or not mentioned at all in available pharmacology textbooks.

Our main goal was therefore to provide sufficient information about existing drug forms, their routes of administration, as well as their methods of delivery, which should serve to enhance the quality of pharmacotherapy in the context of so-called "tailored treatment," whose main effort is to individualize treatment for a specific patient. Although the work focuses on drug application methods, a detailed description of the technical implementation of algorithms and other related procedures is the subject of interest for other fields (nursing, surgical propaedeutics, etc.). Overall, it is a supplementary educational text provided in electronic form, which is extremely popular in today's modern informatized era. Thanks to this, the work can be used at any time at home or in a school environment, comprehensively or progressively, partially. We have also tried to enhance its quality by appropriate content organization, inclusion of practical experiences, as well as the inclusion of colorful images or photographs, overview tables, and appendices.

The textbook is supplemented by test quizzes serving to verify acquired selected knowledge, which are published on the website of the Department of Pharmacology at the Medical Faculty of UPJŠ in Košice (under "Teaching" → "Taught subjects"), and which will be continuously supplemented and updated (http://www.lf.upjs.sk/farmakologia/TEST%201.htm; http://www.lf.upjs.sk/farmakologia/TEST%202.htm).

Although the work is primarily intended for medical students, or students of pharmacy and other healthcare fields, we firmly believe that enriching information will be found in it by beginning graduates of these fields, as well as their teachers.

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Mária Mareková a kol. 

Medical biochemistry is integral parts of basic theoretic knowledge of contemporary graduate at medical faculties. This textbook intends to help the undergraduate students of study branches General Medicine and Dental Medicine for the course of “Medical Biochemistry”. It is structured into 10 chapters concerning several topics: enzymology, cells membrane, metabolism, biochemistry of blood and organs, as well as some parts of clinical biochemistry.

The theoretical knowledge of this subject, which student obtains in the lectures, is verified in laboratory practices and is expanded in seminaries. Our selection of topics makes the text especially appropriate for medical students and managing of problems gives the students satisfactory ground for effective study of medical biochemistry and other related study subjects (e.g. clinical biochemistry, physiology, pathophysiology) in the sense of comprehension of relative continuity and interdependence of biochemical process or their function respectively.

Since the textbook brings only the skeleton survey on the biochemical problematic concerning medicine, students should broaden presented facts by additional study from lectures and/or from other sources. We expect this study literature to serve as a basic study material for mentioned medical study branches for preparation to written part of exam from “Medical Biochemistry”.

Authors

E-book

Daniela Husárová

There is still little complete information about the system of care for adolescents with emotional and behavioral problems, especially in Slovakia.

Therefore, the main aim of this publication is to summarize and present current findings of the Care4Youth project, not only about the system, but also about the role of particular actors involved in the care of these adolescents, including family, professionals and schools.

In the chapters, we take a closer look at the cooperation of all involved actors and, from the point of view of care providers from different types of institutions, we will describe all barriers that negatively affect adequate and effective help as well as suggestions how the identified barriers could be eliminated.

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Martina Zavacká a kolektív

Kniha „DIABETICKÁ NOHA Z POHĽADU CIEVNEHO CHIRURGA“ obsahuje 14 kapitol. Pojednáva o syndróme diabetickej nohy z multidisciplinárneho pohľadu viacerých odborníkov: angiochirurga, diabetológa, chirurga, podiatra, röntgenológa, neurológa a algeziológa. Úvodné kapitoly majú charakter propedeutiky, čo má taktiež význam aj pre pregraduálnu výchovu. Nasledujúce kapitoly sa zaoberajú vznikom syndrómu, výskytom, jeho diagnostikou, terapeutickými postupmi, pridruženými postihnutiami neurologického charakteru, starostlivosťou podiatra a algeziológa pri pretrvávaní bolestí. Ďalšie časti sú vyhradené chirurgickej a endovaskulárnej liečbe tepien cestou cievneho chirurga a intervenčných angiológov. Nezabúdajúc na problematiku amputácií a správnu rehabilitáciu pacientov s diabetom.  V knihe nájdu poučenie cievni chirurgovia, angiológovia, všeobecní chirurgovia, diabetológovia, neurológia, röntgenológovia, podiatri  a všeobecní lekári.

Kniha je zdrojom najnovších teoretických i praktických informácií pre postgraduálnu výchovu vyššie spomenutých odborníkov.

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Tatiana Muchová

Medicína stále napreduje, je stále vo vývoji. Rádiologické zobrazovacie metódy prežívajú stále výrazný rozvoj vďaka prístrojovej technike, ktorá umožňuje zavádzať nové diagnostické metódy, ako sú USG vyšetrenia s kontrastnou látkou, špeciálne CT vyšetrenia, ku ktorým je potrebný viacradový CT prístroj – CT angiografia, CT enteroklýza, CT irigografia, CT virtuálna kolonoskopia. Magnetická rezonancia už v dnešnej dobe nie je nedostupné vyšetrenie, predstavuje výrazný pokrok v diagnostike.

Vďaka moderným prístrojom môžeme vykonávať rôzne intervenčné diagnostické aj terapeutické výkony, ako sú biopsie, drenáže...

Tieto učebné texty sú určené študentom lekárskych fakúlt, obsahuje základné poznatky z rádiológie.

Publikácia je rozdelená na všeobecnú a špeciálnu časť s následným delením podľa jednotlivých modalít a vyšetrovaných orgánov.

Rádiológia predstavuje prácu s obrazovou dokumentáciou, preto aj táto publikácia je obohatená veľkým počtom obrázkov z jednotlivých rádiologických vyšetrovacích modalít.

Vladimíra Tomečková

Nature, as well as the human body, contains an abundant quantity of organic molecules. This textbook describes selected oxygen, sulfur, nitrogen derivatives of hydrocarbons, heterocyclic compounds of their reactions, which are important in the human body or are found in pharmaceutical active substances, poisons, foodstuffs and heat-treated food. The last part of the textbook describes the isomerism of organic compounds, which enables dynamic changes in the structure of molecules that have different properties. Nature is filled with different plants and animals and is the first laboratory to produce bioactive organic natural compounds. These compounds are compatible with human cells and are applicable as therapeutic medicine. There is an effort to reproduce natural molecules in chemical laboratories, but they cannot be as perfect as the natural ones. Synthetic molecules can serve as a model for multiple studies, but there still does not exist a magic panacea pill or a perfect copy of nature, for the treatment of various diseases. Knowledge about the regenerative and toxic effect of medicinal substances in dependence on their structure (type and number of substituents) is very important for the understanding of their role in modulation of health and disease in dependence on their concentration. Compounds can be used daily only in recommended doses (higher doses can be toxic), but still will not replace a healthy diet. People need a varied diet to be healthy, in which are all necessary nutrients, what Hippocrates demonstrated long ago “Let food be the medicine, and let medicine be the food.” This book is written for students who select bioorganic chemistry subject during the study of general medicine or dentistry as well as for motivated students who would like to practice their knowledge and wish to improve in this subject and for students who would like to learn simplified basic organic reactions with their future application in biochemistry. Learn the simple models mainly through creative simple instruction by using different colours, by repetition, practice by drawing of formulas by hand (at least three times) and memorization of common names of compounds and their reactions which have application in biochemistry. Thus, establishing simple educational methods how to distinguish organic molecules according to the colours of a functional group can promote universal learning for all students who thought that chemistry is a difficult subject, but hopefully they change their opinion after study of this book.

Keywords: organic molecules, oxygen, sulfur, nitrogen derivatives of hydrocarbons, heterocyclic compounds, chemical reactions, isomerism of organic compounds

E-book

Marek Stupák et al.

A well-known proverb says: "It is better to see once than to hear a hundred times." With this in mind, the electronic version of the teaching materials has been designed, as we are convinced that practical laboratory experience is irreplaceable and still holds its significance in university studies.

In the provided teaching texts, you will find a set of experiments that complement and help better understand the theoretical knowledge gained through self-study as well as lectures in an appropriate manner. Additionally, this e-version allows students, after printing and subsequently completing individual tables, observations, and conclusions, to submit them as a laboratory report that confirms they have successfully mastered the assigned tasks.

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E-book

Adriana Boleková et al.

The book is primarily intended for first-year university students, but it is suitable for anyone who needs to learn. Students can find here the basic principles of learning, principles of how to preserve knowledge, how to concentrate without wasting time, how not to stress before a test or exam and many other practical tips. By acquiring simple knowledge, students will be able to learn effectively with the principles of brain-compatible learning in a way that they will acquire as much information as possible in the shortest period of time with maximum retention; that is minimal forgetting.

The book can serve not only as a theoretical background, but also as a practical tool for mastering university education.

The goal was to create a balanced material that would be an interesting source not only for first-year university students, but also for students of higher years and for everyone with a need of lifelong learning.

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Mária Frankovičová - Jana Kaťuchová

Dear readers and students,

The book “Surgery for Medical Students“ is a textbook intended to be used by those studying at medical faculties and in other healthcare fields. In this textbook, the authors, encompassing all surgical specialties, have tried to provide the reader with a holistic context of the study material intended to be used in preparation for the state exam from surgery. I thank all the co-authors for their willingness and cooperation. To the students I hope you have a pleasant time reading and studying the book.

Prof. MUDr. Mária Frankovičová, PhD

E-publication

Štefan Tóth a kol.

After several years of teaching experience in the compulsory subject of histology and histological techniques, it became clear that there was a need to refine, standardize, and facilitate the study of bachelor's degree students. We therefore decided to develop university textbooks for the theory of general histology in bachelor's degree programs: Laboratory Examination Methods in Healthcare, Physiotherapy, and Nursing. The new textbooks are based on the syllabi for the subjects "Histology and Pathology" and "Fundamentals of Histology" for the given study programs. The content is designed to make the study of histology as easy as possible and to help students quickly orient themselves in the given topic. At the same time, the texts aim to streamline cooperation between students and teachers in lectures and practical exercises, emphasizing the important structures of individual cell and tissue types in light microscope images, which is the primary goal and task of general histology.

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E-book

Peter Berek

University scripts “Visceral pathology of vascular origin“analyze one of the most challenging vascular regions, the aorta and the visceral aortic branches, from the surgical perspective. The diagnostic and the treatment aneurysms of the abdominal aorta are dedicated to the first chapter. Early diagnostic and operative treatment is crucial in the treatment of ruptured aneurysms of the abdominal aorta. Shortening of the interval between the patient’s arrival with ruptured aneurysm of the abdominal aorta into the hospital and the beginning of the operation decreased the perioperative mortality. This shortening, together with the use of the cell savers, led to the dropping of perioperative mortality from 50% to 20%. The diagnostics and surgical treatment of the acute and chronic occlusion of the aorta and iliac arteries are analyzed in the second chapter. In this chapter, the focus is given to the aortobifemoral bypass as “the gold standard“ of the surgical therapy of aortoiliac atherosclerosis. The management of acute mesenteric ischemia is the content of the third chapter. Acute mesenteric ischemia is a severe condition with high mortality. The problem of acute mesenterial ischemia is a delayed diagnostic that is the reason for poor therapeutical outcomes of the disease. The possible imagine studies and operations used in treating acute mesenteric ischemia are brought in this chapter. Chronic mesenteric ischemia leads to cachexia. The diagnosis of chronic mesenterial ischemia is one of the most demanding, and surgical therapy used in the treatment of chronic mesenterial ischemia also belongs to the most challenging operations. Left-sided colon ischemia belongs to the severe complications of the aortoiliac reconstructions. Left-sided colon ischemia has a high mortality. In the prevention of the left-sided colon, ischemia is preserving at least one internal iliac artery. The complex diagnostics treatment of intraabdominal compressive syndromes as Dunbar syndróme, „Nutcracker“ syndróme a Wilkie syndróme, analyzed in the last chapter.

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E-book

Adriana Boleková - Natália Hvizdošová (eds.)

Košický morfologický deň je každoročné májové stretnutie morfológov, ktorého sa zúčastňujú najmä košické morfologické pracoviská. Pri tejto príležitosti sa pravidelne vydáva zborník vedeckých prác. Tohoročný zborník je vydaný pri príležitosti 27. košického morfologického dňa. V zborníku autori prezentujú výsledky svojej vedecko-výskumnej a pedagogickej činnosti, ktoré majú charakter teoretických prehľadových štúdií a výskumných prác.

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E-book

Iveta Domoráková - Štefan Tóth - Zuzana Fagová - Kristína Čurgali - Viera Eliášová - Alexandra Kunová - Monika Holodová

The peer-reviewed textbook and microscopic atlas is aimed at understanding the basic microscopic structure of cells and tissues in a light microscope. Texts in the textbook are complemented by a rich set of histologic micrographs with basic and specific staining techniques.

All histologic micrographs were prepared by the author's team at the Department of Histology and Embryology, Faculty of Medicine, UPJŠ.

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Marián Sabol - Helga Kostelná - Leonard Siegfried

Cieľom učebných textov je poskytnúť študentom medicíny a príbuzných odborov   poznatky o základných imunologických metódach, ktoré sa využívajú v klinickej praxi. V učebných textoch sú zahrnuté metódy na vyšetrenie fagocytózy, komplementu, imunoglobulínov, autoprotilátok,  HLA molekúl a T lymfocytov.  Súčasťou textov sú aj  postupy pre izoláciu a stanovenie počtu vybraných  typov buniek imunitného systému. Kombinácia klasických  metód (rozetové testy, fluorescenčná mikroskopia) a moderných metód   (napríklad prietoková cytometria a  ELISPOT) umožňuje orientáciu v základných laboratórnych metódach imunológie.

 Miroslav Mydlík - Július Vajó (eds.)