Metódy v genetike človeka a molekulovej biológii

E-book

Jozef Židzik - Terézia Hudáková - Martina Šemeláková - Ján Šalagovič

Methods in human genetics and molecular biology encompass various experimental, diagnostic and analytical techniques used to investigate the structure, function, expression, and regulation of genes, as well as general molecular processes in human cells. The university textbook Methods in Human Genetics and Molecular Biology provides a comprehensive overview of classical and modern experimental and analytical procedures. In fifteen chapters, it addresses methods such as PCR, RFLP, FISH, Western blot, DNA sequencing, DNA microarrays, molecular cloning, cytogenetic analysis, and forensic genetic analysis. The book is primarily intended as study material for the course of the same name taught in the 2nd year of study at the UPJŠ Faculty of Medicine, but it can also be used by all university students in the fields of biology, biotechnology, and related disciplines.

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978-80-574-0401-9

Data sheet

Method of publication:
E-book (pdf)
Authors:
Jozef Židzik - Terézia Hudáková - Martina Šemeláková - Ján Šalagovič
Document type:
Academic textbook - scripts
Number of pages:
236
Available from:
23.04.2025
Year of publication:
2025
Edition:
1st edition
Publication language:
Slovak
Faculty:
Faculty of Medicine
Note:
Grantová podpora: KEGA 024UPJŠ-4/2024
License:
CC BY NC ND (Uveďte autora - Nepoužívajte komerčne - Nespracovávajte)
- Free for download

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23.KOŠICKÝ MORFOLOGICKÝ DEŇ

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Proceedings of Scientific Works

The Košice Morphological Day is an annual May meeting of morphologists, primarily attended by Košice morphological workplaces. On this occasion, a collection of scientific works is regularly published.

This year's collection was published on the occasion of the 23rd Košice Morphological Day, which did not take place due to the poor epidemiological situation.

In the collection, the authors present the results of their scientific-research and pedagogical activities, which are in the form of theoretical overview studies and research works.

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Clinical Biochemistry

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Eva ĎurovcováMária Mareková

Clinical Biochemistry - selected chapters - MEFANET >>> 

After 7 years, we finally reworked the textbook on the subject of clinical biochemistry at UPJŠ FM in Košice. We have innovated information in accordance with recommendations of professional medical societies and added new chapters. As the scope of the subject is limited, the textbook does not cover all issues of biochemical diagnostics. It focuses on disorders of water-ion and acid-base balance disorders, and basic laboratory diagnostics of diseases of selected organs.

The textbook of clinical biochemistry has the ambition to become a practical aid for senior medical students and beginning doctors in the study of laboratory medicine. It should make it easier for them to orientate themselves in routinely used clinical-biochemical examinations and could form a springboard for a more detailed studying of laboratory methods and their use in diagnostic and monitoring algorithms.
Like any medical discipline, clinical biochemistry is evolving rapidly and gradually integrating with other areas of laboratory medicine. New diagnostic methods penetrate deeper into the essence of the biochemical mechanisms of the human body, and "omic" methods are gaining ground. It is almost sure that in a few years, laboratory examination looks quite different from today. If this publication quite hypothetically reaches its next edition, many chapters will need to updated, and new chapters written following the up-to-date status.
Authors thanks to their colleagues and reviewers for their professional comments and constructive criticism of the text - prof. Jaroslav Racek, MD, DrSc. from FM UK in Pilsen.
Authors thanks very kindly too prof. MUDr. Dušan Dobrota, CSc. (JFM UK Martin) and doc. MVDr. Zuzana Kostecká, PhD. (UVMP, Košice), who read and wrote review of this textbook.

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Neurochirurgia pre študentov medicíny

€19.00
Availability: 49 In Stock

Miroslav Gajdoš - Vladimír Kaťuch

  „Neurochirurgia pre študentov medicíny“ je určená pre študentov lekárskych fakúlt. Základné informácie o neurochirurgii získajú aj študenti príbuzných odborov /zubné lekárstvo/, ale aj absolventi lekárskych fakúlt v začiatkoch svojej klinickej praxe.

Učebný text je rozdelený do desiatich kapitol. Tie sa ďalej delia na podkapitoly.

Prvá kapitola je zameraná na dejiny chirurgie, následne na dejiny neurochirurgie. V tejto kapitole autor pripomína, že operované lebky patria k najstarším dôkazom operačnej činnosti našich predkov. 

Druhá a tretia kapitola  je venovaná diagnostike a základným operačným výkonom.

Pre pochopenie patologicko-fyziologických dejov je potrebné pozorne preštudovať štvrtú kapitolu, v ktorej autor popisuje základné patologické mechanizmy, ktoré pôsobia na povrchu ale aj v hĺbke mozgových tkanív.

Piata kapitola je venovaná závažnej problematike  -  vrodeným chybám mozgu, miechy a ich podporných štruktúr.

Nie menej závažnou problematikou pre neurochirurgov sú nádory CNS,  periférnych nervov, lebky a chrbtice. Tie sú popísané v šiestej kapitole.                 

V siedmej kapitole sú popísané cievne ochorenia CNS: autor popisuje aneuryzmy mozgových ciev, ich diagnostiku a liečbu, ďalej cievne malformácie mozgu, artériovenózne malformácie mozgu a v neposlednom rade spinálne artériovenózne malformácie.

8. kapitola je čo do obsahu najrozsiahlejšia. Prináša informácie o poranení pacientov pri úraze. O ich závažnosti, diagnostike a možnej liečbe – konzervatívnej a chirurgickej.

9. kapitola je venovaná nie menej závažnej problematike, a to degeneratívnym ochoreniam chrbtice.

V 10. kapitole sa autor venuje najnovším metódam liečby chronickej bolesti a epileptochirurgii.

Medical Ethics

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E-book

Nikita Bobrov et al.

History of ethics represents a search for basic principle, which would enable a distinction between moral and immoral, good and bad, right and wrong. The main problem lies in motives, methods and consequences of human conduct. The integrity of medical profession puts emphasis on life-long study and practice according to the professional competence, and last but not least on ethical principles and rules of medical ethics.
Medical ethics, as a part of bioethics, is currently taking on a huge importance in everyday clinical practice and must face many serious ethical issues regarding the whole system of health care. On general level the decision-making in medical practice is quite easy, based on the requirement to always act in the patient's best interest. However, it is often difficult to know exactly what is best for the patient, in a certain situation, for this particular patient. Also with each progress in medicine and its globalization, the more aspects of human lives are being affected.

Biomedical research, and the new treatment and diagnostic methods it provides are viewed differently in each country, therefore various cultural, religious, social and legal aspects must be considered in their assessment, as well as the basic principles of medical ethics. Worldwide effort on unifying ethical regulations on certain aspects of health care led to the establishment of many legally recognized documents the doctors must be familiar with.

Teaching ethics to students of medical school aims to educate the future doctors towards ethical decision-making, behaviour and professional conduct according to the basic principles of medical ethics.
This textbook provides the basic information on medical ethics for students of medical faculties and serves as a practical introduction to the most common ethical problems of health care provision for their future professional practise.

Authors

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Applications of the Autonomic Nervous System in...

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Ladislav Kočan - Dušan Rybár - Róbert Rapčan

The autonomic nervous system is a vital component of the peripheral nervous system, responsible for maintaining homeostasis and regulating internal processes within the body. Unlike the voluntary control exerted by the central nervous system, the autonomic nervous system operates involuntarily, innervating smooth organs, vessels, skin glands, and even exerting some influence over skeletal muscles in connection with vegetative functions such as breathing, digestion, and the urinary and gonadal systems. Its impact extends crucially to the cardiac muscles of the heart and plays a significant role in endocrine and metabolic functions, thermoregulation, as well as emotional and behavioral responses, including adaptive reactions to stressors.

The aim of this publication is to provide a comprehensive and objective exploration of the anatomical and physiological intricacies of the autonomic nervous system, offering insights into its clinical applications. Within these pages, we meticulously delineate various interventional therapeutic procedures tailored to specific diagnoses related to the autonomic nervous system, aligning each intervention with the anatomical framework of the autonomic system. The efficacy of these procedures is evaluated based on the level of evidence, as per the current recommendations of Evidence-Based Medicine.

This publication is primarily crafted for fifth and sixth-year medical students and medical professionals specializing in anesthesiology, intensive care, and pain medicine. It serves as a valuable resource for gaining a deeper understanding of autonomic nervous system function and its clinical implications, facilitating informed decision-making in clinical practice.

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