Gastroenterology (e-books)

E-book

Jana Mašlanková

Monografia podrobne analyzujúca nové poznatky v SMAD dependentnej dráhe transformujúceho rastového faktora-b je určená poslucháčom lekárskych fakúlt, lekárom v špecializačnej príprave, chirurgom, gastroenterológom, onkológom, úzkej skupine, ktorú zaujímajú najnovšie poznatky v SMAD dependentnej dráhe transformujúceho rastového faktora u pacientov s kolorektálnym karcinómom.

V tejto monografii sa autorka postupne venuje molekulárnym cestám kolorektálnej karcinogenézy, vplyvu jednotlivých genomických aberácií na vznik kolorektálneho karcinómu a hlavne úlohe TGF-b v supresii a taktiež v progresii nádoru. V samostatných kapitolách popisuje úlohy SMAD v procese karcinogenézy a v neposlednom rade sa hlbšie venuje liečbe a hlavne anti TGF-b terapii.

Download the e-book for free (pdf)

E-book

Sylvia Dražilová - Laura Gombošová - Martin Janičko - Ľubomír Skladaný - Eduard Veseliny

University textbooks are focused on undergraduate medical students and young doctors engaged in specialized training in gastroenterology, hepatology, and internal medicine.

The authors aimed to somewhat replace the lack of a concise and straightforward textbook on gastroenterology and hepatology for medical students, while also providing specific, directly applicable information for young doctors in inpatient departments caring for these patients.

Download the e-book for free (pdf)

E-book

Tatiana Kimáková - Vladimír Pavlík

The scientific monograph focuses on the characteristics of free radicals, reactive oxygen and nitrogen species, oxidative stress, and its impact on various diseases. A significant portion is dedicated to antioxidants, their classification based on multiple criteria, the characteristics of selected antioxidants in terms of their functions, manifestations of their deficiency and excess, and the overall antioxidant capacity of the body.

A special section is devoted to enzyme-based antioxidants, natural sources of antioxidants in the form of vitamins, trace elements, flavonoids, polyphenols, and coenzyme Q10. To provide a clearer understanding of antioxidants and their influence on population health, the monograph presents results from a research project included in the program "Research Support for Enhancing the Defense Capabilities of the Czech Republic in NATO Structures."

The research was conducted between 2010 and 2012 as part of preventive rehabilitation programs for professional soldiers with a sports component. The study involved 218 professional soldiers, including 180 men and 38 women, with an average age of 33.3 years. The current health status and dietary habits of the soldiers were assessed using questionnaires.

The study described the saturation of the observed group with antioxidant vitamins and statistically evaluated the relationship between their levels and the risk indicators for the development of cardiovascular diseases. Individual analyses were performed using the Reflotron device calibrated with Reflotron Precinorm control serum. Following blood collection, all participants underwent anthropometric examinations (body weight, height, waist circumference), blood pressure measurements, heart rate monitoring, and physical fitness assessments through simple functional tests.

This scientific monograph is suitable for the scientific community, students of medical, veterinary, and natural sciences, as well as public health students at all levels of university education. It is also intended for informed members of the public.

Authors

Download the e-book for free (pdf)