Ošetrovateľstvo vo vnútornom lekárstve III

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Dominika Jarčušková

The script deals with the issue of harmful alcohol use and its consequences on individuals’ cognitive abilities. The first part is devoted to the diagnosis of dependence syndrome and the assessment of risky drinking according to internationally recognized classifications (ICD, DSM). The following chapters explain the concept of cognition and its main components. Attention is also given to changes in cognitive functions during long-term alcohol abuse. The reader is introduced to the anatomical changes in the brain caused by alcohol. Damage to white matter and disorders of neurotransmission are described. Special focus is placed on diagnoses associated with alcohol use, such as Korsakoff syndrome, Wernicke’s encephalopathy, demyelinating disorders, and hepatic encephalopathy. Attention is also paid to the possibilities of diagnosing cognitive dysfunction. General screening tests such as MMSE or MoCA are presented. More specific tools, such as PHES or BEARNI, are described in greater detail. The script also points out the possibilities of pharmacological treatment. Non-pharmacological approaches, including cognitive remediation therapy and computer-based training, are also discussed. The conclusion is devoted to modern neuromodulation methods, in particular transcranial magnetic stimulation and transcranial direct current stimulation. This university textbook is primarily intended for students of medicine, psychology, and related health sciences.

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Alžbeta Blichárová a kolektív

“Pathology Part 1 (winter semester) - Practical lessons for students of dental medicine” represents the first half of the university textbook designed for the pregradual study of pathology. The textbook complements the lectures of pathology and serves as a source of information for students of dental medicine, that are preparing for the practical as well as the final oral examination.

In this part of the “Pathology” series, fifty-four selected histopathological slides are presented. Each selected slide is provided with general information in relation to etiology and pathogenesis of the disease, as well as with corresponding morphological features, including the gross appearance and the most important histopathological characteristics. The textbook summarizes the basic concepts of general pathology that are necessary to master the broad field of systemic pathology in the second semester.

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Iveta Domoráková - Štefan Tóth - Zuzana Fagová - Kristína Čurgali - Viera Eliášová - Alexandra Kunová - Monika Holodová

The peer-reviewed textbook and microscopic atlas is aimed at understanding the basic microscopic structure of cells and tissues in a light microscope. Texts in the textbook are complemented by a rich set of histologic micrographs with basic and specific staining techniques.

All histologic micrographs were prepared by the author's team at the Department of Histology and Embryology, Faculty of Medicine, UPJŠ.

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Peter Berek

University scripts “Visceral pathology of vascular origin“analyze one of the most challenging vascular regions, the aorta and the visceral aortic branches, from the surgical perspective. The diagnostic and the treatment aneurysms of the abdominal aorta are dedicated to the first chapter. Early diagnostic and operative treatment is crucial in the treatment of ruptured aneurysms of the abdominal aorta. Shortening of the interval between the patient’s arrival with ruptured aneurysm of the abdominal aorta into the hospital and the beginning of the operation decreased the perioperative mortality. This shortening, together with the use of the cell savers, led to the dropping of perioperative mortality from 50% to 20%. The diagnostics and surgical treatment of the acute and chronic occlusion of the aorta and iliac arteries are analyzed in the second chapter. In this chapter, the focus is given to the aortobifemoral bypass as “the gold standard“ of the surgical therapy of aortoiliac atherosclerosis. The management of acute mesenteric ischemia is the content of the third chapter. Acute mesenteric ischemia is a severe condition with high mortality. The problem of acute mesenterial ischemia is a delayed diagnostic that is the reason for poor therapeutical outcomes of the disease. The possible imagine studies and operations used in treating acute mesenteric ischemia are brought in this chapter. Chronic mesenteric ischemia leads to cachexia. The diagnosis of chronic mesenterial ischemia is one of the most demanding, and surgical therapy used in the treatment of chronic mesenterial ischemia also belongs to the most challenging operations. Left-sided colon ischemia belongs to the severe complications of the aortoiliac reconstructions. Left-sided colon ischemia has a high mortality. In the prevention of the left-sided colon, ischemia is preserving at least one internal iliac artery. The complex diagnostics treatment of intraabdominal compressive syndromes as Dunbar syndróme, „Nutcracker“ syndróme a Wilkie syndróme, analyzed in the last chapter.

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Mária Mareková - Marek Stupák - Peter Urban - Jana  Mašlanková -

Beáta Hupková - Miroslava Rabajdová

Publikácia je určená záujemcom o štúdium na UPJŠ v Košiciach, Lekárskej fakulte v odbore všeobecné lekárstvo a zubné lekárstvo. Obsahuje 1500 modelových otázok z chémie, ktoré sú spracované v súlade so vzdelávacím programom na gymnáziách a ktoré tvoria podklady písomných testov na prijímacích skúškach. Otázky na prijímacích skúškach však nemusia presne kopírovať otázky v tejto publikácii. Odpovede na otázky sú riešené formou ponúkaných variantných odpovedí obsahujúcich správne aj nesprávne možností, pričom správne odpovede sú uvedené v kľúči na konci publikácie. Táto publikácia vám poskytne možnosť overiť si hĺbku a rozsah vašich vedomostí z chémie, ktoré ste nadobudli počas stredoškolského štúdia a zároveň vám uľahčí prípravu na úspešné absolvovanie prijímacej skúšky. Autori problematiku rozdelili do kapitol, čo vám umožní rýchlo sa zorientovať a zistiť, ktorej oblasti sa musíte v štúdiu viac venovať. Cieľom predkladanej publikácie je umožniť každému uchádzačovi, ktorý má o štúdium na lekárskej fakulte vážny záujem, dobre sa pripraviť na prijímacie konanie a v prípade prijatia, mať dobrý základ na štúdium daného odboru.

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Tatiana Kimáková - Vladimír Pavlík

The scientific monograph focuses on the characteristics of free radicals, reactive oxygen and nitrogen species, oxidative stress, and its impact on various diseases. A significant portion is dedicated to antioxidants, their classification based on multiple criteria, the characteristics of selected antioxidants in terms of their functions, manifestations of their deficiency and excess, and the overall antioxidant capacity of the body.

A special section is devoted to enzyme-based antioxidants, natural sources of antioxidants in the form of vitamins, trace elements, flavonoids, polyphenols, and coenzyme Q10. To provide a clearer understanding of antioxidants and their influence on population health, the monograph presents results from a research project included in the program "Research Support for Enhancing the Defense Capabilities of the Czech Republic in NATO Structures."

The research was conducted between 2010 and 2012 as part of preventive rehabilitation programs for professional soldiers with a sports component. The study involved 218 professional soldiers, including 180 men and 38 women, with an average age of 33.3 years. The current health status and dietary habits of the soldiers were assessed using questionnaires.

The study described the saturation of the observed group with antioxidant vitamins and statistically evaluated the relationship between their levels and the risk indicators for the development of cardiovascular diseases. Individual analyses were performed using the Reflotron device calibrated with Reflotron Precinorm control serum. Following blood collection, all participants underwent anthropometric examinations (body weight, height, waist circumference), blood pressure measurements, heart rate monitoring, and physical fitness assessments through simple functional tests.

This scientific monograph is suitable for the scientific community, students of medical, veterinary, and natural sciences, as well as public health students at all levels of university education. It is also intended for informed members of the public.

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Ladislav Kočan-Dušan Rybár-Róbert Rapčan

The autonomic nervous system is a vital component of the peripheral nervous system, responsible for maintaining homeostasis and regulating internal processes within the body. Unlike the voluntary control exerted by the central nervous system, the autonomic nervous system operates involuntarily, innervating smooth organs, vessels, skin glands, and even exerting some influence over skeletal muscles in connection with vegetative functions such as breathing, digestion, and the urinary and gonadal systems. Its impact extends crucially to the cardiac muscles of the heart and plays a significant role in endocrine and metabolic functions, thermoregulation, as well as emotional and behavioral responses, including adaptive reactions to stressors. The aim of this publication is to provide a comprehensive and objective exploration of the anatomical and physiological intricacies of the autonomic nervous system, offering insights into its clinical applications. Within these pages, we meticulously delineate various interventional therapeutic procedures tailored to specific diagnoses related to the autonomic nervous system, aligning each intervention with the anatomical framework of the autonomic system. The efficacy of these procedures is evaluated based on the level of evidence, as per the current recommendations of Evidence-Based Medicine. This publication is primarily crafted for fifth and sixth-year medical students and medical professionals specializing in anesthesiology, intensive care, and pain medicine. It serves as a valuable resource for gaining a deeper understanding of autonomic nervous system function and its clinical implications, facilitating informed decision-making in clinical practice.

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Ivana Skoumalová - Zuzana Dankulincová

The publication entitled Competencies for clinical practice in the field of communication with the patient serves as the background and teaching material.

The text is structured to bring theoretical knowledge about the topic, current research findings in the field and practical tips for training skills in practice. It provides clear information on individual parts of the training and is designed to acquire knowledge that is the basis for practical skills in medical communication, especially in communication with patients.

It is intended for general and dental students to deepen their knowledge and acquire missing skills in medical communication, which are evidence-based and research-validated skills that have a demonstrable positive impact on patient communication.

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Ingrid Madárová - Lívia Barnišinová - Veronika Pálová

Táto učebnica je určená pre zahraničných študentov medicíny – začiatočníkov – ako slovenčina na špecifický účel výučby. Jej cieľom je pomôcť zahraničným študentom, ktorí (1) študujú medicínu (2) v cudzom jazyku (anglický jazyk) a (3) v zahraničí (Slovensko) zvládnuť výzvu pri príprave na praktickú časť ich štúdia – konverzácia s pacientom v Slovenskom jazyku.Zámerom je poskytnúť študentom krok za krokom najfrekventovanejšie slovné spojenia a výrazy potrebné pri komunikácii s pacientom. Lekcie sa zameriavajú hlavne na slovnú zásobu týkajúcu sa častí ľudského tela a na základné symptómy a príznaky chorôb.Dôraz je kladený na krátke dialógy medzi lekárom a pacientom. Pri precvičovaní dialógov sú študenti vedení k nácviku komunikácie so zreteľom na porozumenie, bez prípadných obáv o gramatickú správnosť. Gramatické javy sú predstavované postupne, cez jednoduché  pomôcky – „tipy“.V prípade potreby si môžu študenti nájsť a doplniť si „chýbajúce časti gramatiky“ prostredníctvom odkazov na odporúčanú literatúru. Cieľom tejto knihy je uľahčiť a zefektívniť celý proces štúdia/osvojenia si (lekárskej) slovenčiny.

Radoslav Morochovič - Rastislav Burda -

Ľuboš Tomčovčík - Peter Cibur - Štefan Ivanecký

Vysokoškolský učebný text určený pre študentov všeobecného lekárstva, zubného lekárstva a fyzioterapie, ktorý obsahuje podstatné časti z predmetu úrazová chirurgia potrebných na zvládnutie vysokoškolského štúdia.

Lucia Dimunová - Jana Raková - Gabriela Štefková

Květuše Lovásová a kol. 

Despite the wide range of high quality textbooks offered on the Slovak market there is no publication with colorful pictures and schemes that can serve as an principal tool for practical and theoretical teaching of neuroanatomy for future psychologists in non-medical academic programmes of Arts and Science Faculties. Following new trends in methods of teaching, it is necessary to pay more attention to quality, depth, and effectiveness of education.

Such kind of illustrated textbook with the interesting graphic design should connect this important morphological subject and clinical medicine to understand the nervous system in the clinical context. This publication was created by using of original, new detailed pictures, and graphic schemes and was supplemented with a short clinical notes. It will be very helpfull to understand the details of neuroanatomical structures and brain regions.

We hope that originality and details of this book will find its application in studies of neuroanatomy for psychologists. 

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Erik Dosedla

Laparoscopic surgical techniques are among the most frequently performed operations today. Throughout their short history, they have undergone many modifications, mainly related to miniaturization and the development of computer technology. The rapid development of laparoscopy over the last twenty years has led to changes in the indications, with minimally invasive procedures gradually replacing standard classical procedures.

Laparoscopic surgery offers significant benefits to the patient, but it also increases the demands on the surgical team.

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M.Stupák - P.Urban - J.Mašlanková - M.Mareková

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Miriam Kozárová

The publication "News in Diabetology and Lipidology" focuses on extremely relevant topics in diabetology and lipidology, reflecting the state of these issues in light of the recommendations from professional societies from 2019. In diabetology, it primarily addresses the intensification of antidiabetic treatment using modern drug classes—specifically, incretin enhancers and sodium-glucose cotransporter-2 (SGLT-2) inhibitors (gliflozins). Few medical fields have experienced such a development of new pharmacological options as diabetology has in the last two decades. While pharmacotherapy for type 2 diabetes (DM2) was limited to the use of biguanides, sulfonylurea derivatives, and insulin throughout the second half of the last century, recent years have introduced entirely new groups of oral antidiabetics with cardio- and nephroprotective effects. In lipidology, it pertains to the new recommendations from the European Atherosclerosis Society (EAS) with new treatment goals for serum lipids and lipoproteins, including the use of biological therapies.

This textbook is primarily intended for medical students in doctoral studies and doctoral candidates, as well as for physicians preparing for specialization exams in internal medicine, endocrinology, diabetology, metabolic disorders and nutrition, as well as cardiology and angiology. I believe that readers will find information in this publication that will aid them in their studies and translate into their daily clinical practice.

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Ladislav Kočan - Dušan Rybár - Róbert Rapčan

The autonomic nervous system is a vital component of the peripheral nervous system, responsible for maintaining homeostasis and regulating internal processes within the body. Unlike the voluntary control exerted by the central nervous system, the autonomic nervous system operates involuntarily, innervating smooth organs, vessels, skin glands, and even exerting some influence over skeletal muscles in connection with vegetative functions such as breathing, digestion, and the urinary and gonadal systems. Its impact extends crucially to the cardiac muscles of the heart and plays a significant role in endocrine and metabolic functions, thermoregulation, as well as emotional and behavioral responses, including adaptive reactions to stressors.

The aim of this publication is to provide a comprehensive and objective exploration of the anatomical and physiological intricacies of the autonomic nervous system, offering insights into its clinical applications. Within these pages, we meticulously delineate various interventional therapeutic procedures tailored to specific diagnoses related to the autonomic nervous system, aligning each intervention with the anatomical framework of the autonomic system. The efficacy of these procedures is evaluated based on the level of evidence, as per the current recommendations of Evidence-Based Medicine.

This publication is primarily crafted for fifth and sixth-year medical students and medical professionals specializing in anesthesiology, intensive care, and pain medicine. It serves as a valuable resource for gaining a deeper understanding of autonomic nervous system function and its clinical implications, facilitating informed decision-making in clinical practice.

Download the e-book for free (pdf)