Základy hodnotenia kardiovaskulárneho rizika: nástroje a aplikácie

Mária Frankovičová - Jana Kaťuchová

Dear readers and students,

The book “Surgery for Medical Students“ is a textbook intended to be used by those studying at medical faculties and in other healthcare fields. In this textbook, the authors, encompassing all surgical specialties, have tried to provide the reader with a holistic context of the study material intended to be used in preparation for the state exam from surgery. I thank all the co-authors for their willingness and cooperation. To the students I hope you have a pleasant time reading and studying the book.

Prof. MUDr. Mária Frankovičová, PhD

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Monika Halánová-Leonard Siegfried

Although chronic non-communicable diseases currently dominate overall morbidity and mortality in developed countries, epidemics of infectious diseases, especially those caused by new or emerging pathogens, occur more frequently and spread faster and further in new territories. The starting factors of this threat are mainly ecological and climatic changes and changes in human demography and behaviour. The growing resistance to ATB is also very serious, as a result of which there is a significant increase in the incidence of infectious diseases and their spread to new geographical locations. Current problems of epidemiology and microbiology in research and clinical practice are mainly focused on rapid detection and subsequent response to diagnosed diseases. The correct diagnosis of an infectious disease is the result of a clinical picture, knowledge of the current epidemiological situation and laboratory confirmation of the etiological agent. The identification of microorganisms allows us to establish the correct definitive diagnosis and subsequent targeted therapy, but also to start immediately with appropriate anti-epidemic measures to control the spread of the infectious agent.

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Roman Beňačka a kolektív

Prvé vydanie zborníka vybraných kapitol z Patologickej fyziológie pre zdravotnícke odbory, ktorý má slúžiť pre prípravu patofyziológie študentov Ošetrovateľstva, Verejného zdravotníctva, Fyzioterapie a iných podobných odborov bakalárskeho a magisterského štúdia na Lekárskych fakultách a vysokých školách zdravotného zamerania. Prednosťou učebnice oproti doterajším titulom je zameranie na modernú pedagogickú prezentáciu a štrukturalizáciu textu, pomáhajúcu pri rýchlej orientácii a zapamätaní s ilustratívnymi obrázkami a dátovo bohatými tabuľkami. Kniha je vo formáte obdobnom u zahraničných titulov.

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Erik Dosedla

A uterine scar is currently a significant medical problem. Uterine scars most commonly occur after a Cesarean section, which is one of the most frequent laparotomic surgeries (Yazicioglu et al., 2006). The frequency of Cesarean sections increased between 1990 and 2014 in the USA from 21.2% to 32.2% (Hamilton et al., 2015), in Great Britain from 12% to 26.2% (NHS Maternity Statistics - England, 2013-14: Summary Report, 2015), and in the Slovak Republic from 8.7% to 31% (Národné centrum zdravotníckych informácii, 2016).

After a Cesarean section (CS), there is a risk of abnormal healing of the uterotomic wound, which can result in the development of certain pathological conditions in consecutive pregnancies (uterine rupture, ectopic pregnancy in the Cesarean scar, placental disorders) (Seow et al., 2004; Oyelese and Smulian, 2006; Fitzpatrick et al., 2012). In addition, a defect in the Cesarean scar is associated with chronic dysmenorrhea, chronic pelvic pain, infertility, and postmenstrual spotting (Wang et al., 2009; Bij de Vaate et al., 2011).

Ultrasound is a valuable examination method in the diagnostic and therapeutic management of these pathological conditions.

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Magdaléna Hagovská a kol. 

Vysokoškolská učebnica Praktická kinezioterapia je určená fyzioterapeutom v rámci pregraduálneho, ale aj postgraduálneho vzdelávania. Je komplexne prepracovanou, opravenou a rozšírenou publikáciou pôvodného textu skrípt Najčastejšie používané liečebné metodiky pre fyzioterapeutov (Hagovská, Mihalečková, 2012).
Fyzioterapia sa dotýka takmer všetkých základných klinických odborov. Z toho vyplýva, že fyzioterapeuti by mali ovládať základné poznatky o špeciálnych metódach, ktoré sa zaoberajú fyzioterapiou vertebrologických a neurologických pacientov, pacientov s ortopedickým ochorením, s gynekologickými a urologickými problémami, a pacientov s psychosomatickou diagnózou. Väčšina popísaných najznámejších 44 liečebných metód obsahuje obrázkovú prílohu, na základe ktorej študenti dokážu lepšie pochopiť uvádzané techniky a predísť chybnému vykonávaniu jednotlivých techník.

Autori

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Magdaléna Hagovská - Alena Buková - Ľubomír Lachváč

Overweight as a risk factor for the development of civilization diseases and urogenital dysfunctions

Overweight and obesity represent a significant risk factor for the development of several diseases of civilisation, such as cardiovascular disease, type 2 diabetes mellitus and various forms of cancer. They also contribute significantly to urogenital dysfunctions such as urinary incontinence, overactive bladder and pelvic organ prolapse. Mechanisms that link excess weight to these dysfunctions include increased intra-abdominal pressure, hormonal changes, and chronic inflammatory processes that negatively affect the structure and function of the urogenital system. Prevention and treatment of overweight and obesity are therefore crucial not only in terms of reducing the risk of civilization diseases, but also in improving the quality of life through the prevention and treatment of urogenital dysfunctions.

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Eva Ďurovcová - Mária Mareková

Clinical Biochemistry - selected chapters - MEFANET >>> 

After 7 years, we finally reworked the textbook on the subject of clinical biochemistry at UPJŠ FM in Košice. We have innovated information in accordance with recommendations of professional medical societies and added new chapters. As the scope of the subject is limited, the textbook does not cover all issues of biochemical diagnostics. It focuses on disorders of water-ion and acid-base balance disorders, and basic laboratory diagnostics of diseases of selected organs.

The textbook of clinical biochemistry has the ambition to become a practical aid for senior medical students and beginning doctors in the study of laboratory medicine. It should make it easier for them to orientate themselves in routinely used clinical-biochemical examinations and could form a springboard for a more detailed studying of laboratory methods and their use in diagnostic and monitoring algorithms.
Like any medical discipline, clinical biochemistry is evolving rapidly and gradually integrating with other areas of laboratory medicine. New diagnostic methods penetrate deeper into the essence of the biochemical mechanisms of the human body, and "omic" methods are gaining ground. It is almost sure that in a few years, laboratory examination looks quite different from today. If this publication quite hypothetically reaches its next edition, many chapters will need to updated, and new chapters written following the up-to-date status.
Authors thanks to their colleagues and reviewers for their professional comments and constructive criticism of the text - prof. Jaroslav Racek, MD, DrSc. from FM UK in Pilsen.
Authors thanks very kindly too prof. MUDr. Dušan Dobrota, CSc. (JFM UK Martin) and doc. MVDr. Zuzana Kostecká, PhD. (UVMP, Košice), who read and wrote review of this textbook.

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Mária Mareková a kol. 

Medical biochemistry is integral parts of basic theoretic knowledge of contemporary graduate at medical faculties. This textbook intends to help the undergraduate students of study branches General Medicine and Dental Medicine for the course of “Medical Biochemistry”. It is structured into 10 chapters concerning several topics: enzymology, cells membrane, metabolism, biochemistry of blood and organs, as well as some parts of clinical biochemistry.

The theoretical knowledge of this subject, which student obtains in the lectures, is verified in laboratory practices and is expanded in seminaries. Our selection of topics makes the text especially appropriate for medical students and managing of problems gives the students satisfactory ground for effective study of medical biochemistry and other related study subjects (e.g. clinical biochemistry, physiology, pathophysiology) in the sense of comprehension of relative continuity and interdependence of biochemical process or their function respectively.

Since the textbook brings only the skeleton survey on the biochemical problematic concerning medicine, students should broaden presented facts by additional study from lectures and/or from other sources. We expect this study literature to serve as a basic study material for mentioned medical study branches for preparation to written part of exam from “Medical Biochemistry”.

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Ladislav Kočan - Dušan Rybár - Róbert Rapčan

The autonomic nervous system is a vital component of the peripheral nervous system, responsible for maintaining homeostasis and regulating internal processes within the body. Unlike the voluntary control exerted by the central nervous system, the autonomic nervous system operates involuntarily, innervating smooth organs, vessels, skin glands, and even exerting some influence over skeletal muscles in connection with vegetative functions such as breathing, digestion, and the urinary and gonadal systems. Its impact extends crucially to the cardiac muscles of the heart and plays a significant role in endocrine and metabolic functions, thermoregulation, as well as emotional and behavioral responses, including adaptive reactions to stressors.

The aim of this publication is to provide a comprehensive and objective exploration of the anatomical and physiological intricacies of the autonomic nervous system, offering insights into its clinical applications. Within these pages, we meticulously delineate various interventional therapeutic procedures tailored to specific diagnoses related to the autonomic nervous system, aligning each intervention with the anatomical framework of the autonomic system. The efficacy of these procedures is evaluated based on the level of evidence, as per the current recommendations of Evidence-Based Medicine.

This publication is primarily crafted for fifth and sixth-year medical students and medical professionals specializing in anesthesiology, intensive care, and pain medicine. It serves as a valuable resource for gaining a deeper understanding of autonomic nervous system function and its clinical implications, facilitating informed decision-making in clinical practice.

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Jozef Židzik - Terézia Hudáková - Martina Šemeláková - Ján Šalagovič

Methods in human genetics and molecular biology encompass various experimental, diagnostic and analytical techniques used to investigate the structure, function, expression, and regulation of genes, as well as general molecular processes in human cells. The university textbook Methods in Human Genetics and Molecular Biology provides a comprehensive overview of classical and modern experimental and analytical procedures. In fifteen chapters, it addresses methods such as PCR, RFLP, FISH, Western blot, DNA sequencing, DNA microarrays, molecular cloning, cytogenetic analysis, and forensic genetic analysis. The book is primarily intended as study material for the course of the same name taught in the 2nd year of study at the UPJŠ Faculty of Medicine, but it can also be used by all university students in the fields of biology, biotechnology, and related disciplines.

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Jana Mašlanková

Colorectal carcinoma is the most common malignant tumor of the digestive system, and its rising incidence in Slovakia—particularly among the male population—is alarming. Although significant progress has been made in the diagnosis, screening, and treatment of patients with advanced colorectal cancer, therapeutic options remain limited, necessitating the discovery of additional markers to serve as prognostic predictors.

This monograph aims to draw the attention of the professional community to the critical role and significance of the TGF-β signaling pathway in the initiation, progression, and treatment of colorectal carcinoma. A substantial portion of the text focuses on lesser-known emerging trends and ongoing clinical trials for colorectal cancer patients.

The monograph aspires to provide a balanced resource that serves as an engaging informational tool not only for specialist physicians but also for medical faculty students. By integrating novel insights and clinical data, it seeks to bridge gaps in current understanding and highlight potential avenues for future research and therapy.

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Andrea Madarasová Gecková - Daniela Husárová a kol.

The aim of this publication is to present the latest findings of the international study Health Behavior in School-aged Children (HBSC), regarding the health and health-related behavior of school-aged children in Slovakia.After four years, it again brings information on various topics covering physical and mental health, nutritional behavior, leisure-time activities, use of psychoactive substances, within social environment of school-aged children, including family, school and peers. The publication also presents newfindings connected to objectively measured physical fitness of these children. Finally, data about school-aged children with special educational needs are also presented.The findings play an important role in understanding the needs of the new generation of adolescents and are an important source of information for all those who work with them, not only professionals but also parents.Last but not least, they are also beneficial for all stakeholders and institutions who participate in the preparing of policies and strategies focused on supporting the health of school-aged children.

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Dorota Sopková - Silvia Farkašová Iannaccone

Forensic medicine is a medical discipline that is concerned with the determination of the cause of death in cases of violent and non-violent deaths, as well as the assessment of the effects of violence on the human body, including in cases of living persons. The presented textbook provides a consolidated and comprehensive review of the basic tasks and theoretical knowledge of the field of forensic medicine. Its goal is to provide a theoretical basis for the study of the compulsory subject Forensic Medicine and Medical Law in the study programs General Medicine and Dental Medicine, which has been absent until now. The authors emphasize the need to know the basics of forensic medicine in every medical field and a multidisciplinary approach to solving medico-legal questions.

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Štefan Tóth a kol.

After several years of teaching experience in the compulsory subject of histology and histological techniques, it became clear that there was a need to refine, standardize, and facilitate the study of bachelor's degree students. We therefore decided to develop university textbooks for the theory of general histology in bachelor's degree programs: Laboratory Examination Methods in Healthcare, Physiotherapy, and Nursing. The new textbooks are based on the syllabi for the subjects "Histology and Pathology" and "Fundamentals of Histology" for the given study programs. The content is designed to make the study of histology as easy as possible and to help students quickly orient themselves in the given topic. At the same time, the texts aim to streamline cooperation between students and teachers in lectures and practical exercises, emphasizing the important structures of individual cell and tissue types in light microscope images, which is the primary goal and task of general histology.

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Nikita Bobrov et al.

History of ethics represents a search for basic principle, which would enable a distinction between moral and immoral, good and bad, right and wrong. The main problem lies in motives, methods and consequences of human conduct. The integrity of medical profession puts emphasis on life-long study and practice according to the professional competence, and last but not least on ethical principles and rules of medical ethics.
Medical ethics, as a part of bioethics, is currently taking on a huge importance in everyday clinical practice and must face many serious ethical issues regarding the whole system of health care. On general level the decision-making in medical practice is quite easy, based on the requirement to always act in the patient's best interest. However, it is often difficult to know exactly what is best for the patient, in a certain situation, for this particular patient. Also with each progress in medicine and its globalization, the more aspects of human lives are being affected.

Biomedical research, and the new treatment and diagnostic methods it provides are viewed differently in each country, therefore various cultural, religious, social and legal aspects must be considered in their assessment, as well as the basic principles of medical ethics. Worldwide effort on unifying ethical regulations on certain aspects of health care led to the establishment of many legally recognized documents the doctors must be familiar with.

Teaching ethics to students of medical school aims to educate the future doctors towards ethical decision-making, behaviour and professional conduct according to the basic principles of medical ethics.
This textbook provides the basic information on medical ethics for students of medical faculties and serves as a practical introduction to the most common ethical problems of health care provision for their future professional practise.

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A.A. Ahmetova - A.A. Seidakhmetova - N.D. Kalmenov et al.

Improving the best practices in the provision of the first pre-medical care is one of the priority areas of clinical medicine in most countries of the world. Despite the success in improving the provision of medical care at the level of FPMA and emergency medical care, it is the provision of skilled care at the earliest stages of the disease or emergency conditions that determines the quality of all medical care and the future of the patient.

When rendering emergency care to the sick and injured, the time factor is very important, it prevents irreversible disturbances in the body and creates a good help for the complete cure of the patient. Textbook is designed to improve awareness of the importance of pre-medical aid to non-medical students in central Asian countries.

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