Základy výskumu v zdravotníctve

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Kvetoslava Rimarová a kol.

Učebnica poskytuje komplexný a interdisciplinárny pohľad na problematiku humánnej výživy v kontexte verejného zdravotníctva, hygieny výživy a prevencie ochorení. Je koncipovaná ako základný aj rozširujúci študijný materiál pre študentov zdravotníckych, biomedicínskych a verejno-zdravotníckych odborov, ako aj pre odborníkov pôsobiacich v oblasti výživy, hygieny, potravinárstva a zdravotnej politiky. Publikácia systematicky pokrýva všetky kľúčové oblasti výživy človeka – od základných zložiek potravy (bielkoviny, sacharidy, tuky, vitamíny, minerálne látky), ich biologickej a energetickej hodnoty, cez odporúčané výživové dávky a tvorbu racionálneho jedálnička, až po hodnotenie nutričného stavu populácie. Osobitná pozornosť je venovaná antioxidantom, probiotikám a funkčným potravinám, ktoré predstavujú moderný a dynamicky sa rozvíjajúci segment výživovej vedy.

Učebnica reflektuje aktuálne trendy v stravovaní vrátane alternatívnych spôsobov výživy, prerušovaného pôstu, vysokoproteínových diét a konzumácie spracovaných a ultraprocesovaných potravín, pričom ich hodnotí z hľadiska vedeckých dôkazov, zdravotných prínosov aj rizík. Dôležitou súčasťou je problematika cudzorodých látok v potravinách, potravinárskych aditív a legislatívnych rámcov ich používania, ako aj význam pitnej vody, jej kvalita, úprava a zdravotné riziká spojené s kontamináciou. Publikácia sa venuje aj špecifickým oblastiam, ako sú alimentárne nákazy, výživa v jednotlivých vývinových obdobiach detí, nemocničné stravovanie a diétne systémy.

Praktickú hodnotu učebnice zvyšuje zaradenie metodicky spracovanej praktickej časti zameranej na mikrobiologické hodnotenie pokrmov rýchleho občerstvenia, založenej na reálnych dátach regionálnych úradov verejného zdravotníctva. Text je spracovaný prehľadne, s využitím tabuliek, obrázkov a aktuálnej odbornej literatúry, čo umožňuje čitateľovi nielen osvojenie teoretických poznatkov, ale aj ich aplikáciu v praxi. Učebnica predstavuje ucelený, moderný a vedecky podložený zdroj poznatkov o výžive ako jednom zo základných determinantov zdravia populácie.

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Miroslav Gajdoš - Igor J.Šulla a kol. 

Učebnica pre lekárov a študentov všeobecného lekárstva

Medicína je neprestajne sa vyvíjajúca vedná disciplína. Základný výskum v spojení s klinickou praxou rozširujú súčasné vedomosti, čo sa veľmi výrazne prejavuje aj v neurovedách, v praktickej podobe hlavne v neurofyziológii, neurofarmakológii, neurológii, diagnostickej aj intervenčnej neurorádiológii a v neurochirurgii. V priebehu ostatných troch desaťročí neurovedy prekonali pozoruhodný vývoj. Podnietili ho potreby praxe a umožnilo využitie poznatkov biológie, chémie, biochémie, aplikovanej matematiky, výpočtovej techniky a fyzikálnych objavov realizovaných v moderných prístrojoch i liečebných postupoch. To všetko podstatne uľahčilo, spresnilo a urýchlilo diagnostiku ochorení nervového systému, umožnilo relatívne bezpečné chirurgické zásahy na štruktúrach v minulosti nedostupných a otvorilo nové perspektívy, hlavne v oblasti reparácie poškodených tkanív, respektíve ich funkcií autotransplantáciou kmeňových/progenitorových buniek, terapeutickými zásahmi na genómovej, prípadne proteómovej úrovni. Ako vysokoškolskí učitelia sa každodenne stretávame nielen s mimoriadnym záujmom študentov i zdravotníckych pracovníkov o nové poznatky, ale aj s určitou neistotou pri posudzovaní možností, ktoré jednotlivé disciplíny patriace do skupiny neurovied ponúkajú. Jednou z príčin spomenutého javu je pravdepodobne časový faktor, keď najnovšie poznatky ešte nestačili preniknúť do odbornej literatúry, alebo v nej nie sú dostatočne zdôraznené. Druhou príčinou môže byť pomerne malá skúsenosť s niektorými ochoreniami nervového systému, ktoré sa síce vyskytujú zriedkavejšie, ale ich následky sú závažné. Cieľ, ktorý sme sledovali napísaním tejto učebnice, bolo aspoň čiastočne odstrániť spomenuté nedostatky všetkých odborných publikácií.

Počas prípravy rukopisu sme sa snažili, aby terapeutické postupy, názvy liekov a ich dávkovanie boli v súlade s najnovšími poznatkami vedy a klinickej praxe. Oprávnene však môžeme predpokladať, že budúce objavy zmenia súčasný pohľad na problematiku diagnostiky aj liečby ochorení nervového systému.

Vysokoškolská učebnica je určená študentom všeobecného lekárstva UPJŠ Lekárskej fakulty v Košiciach a lekárom, zameraným hlavne na všeobecné lekárstvo.

Kolektív autorov

 Ingrid Dravecká 

College textbook "Investigation methods in Diabetology" is designed for students of medicine. It can help them in preparing for an exam from internal medicine but specially in preparing for a state exam from internal medicine. The introduction is devoted to classification and diagnostic criteria of diabetes mellitus. Further It describes investigation options (clinical, laboratory, imaging) of different types of diabetes mellitus as well as its acute and chronic complications. At the end there are given diagnostics and classification of the individual components of the metabolic syndrome, obesity and dyslipidemia.

Author

Lucia Dimunová et al.

Nutrition is among the fundamental needs of humans. A good nutritional status directly impacts an individual’s growth and development, health maintenance, and quality of life. This university textbook addresses nutrition in the context of dietetics and therapeutic nutrition, offering an overview of basic food components such as proteins, fats, carbohydrates, vitamins, and minerals.

It provides detailed insights into nutritional requirements across different developmental stages. In assessing nutritional status, it explores evaluation methods, including nutritional screening, anthropometric measurements, clinical assessments, and laboratory tests.

The text clarifies the structure of nutritional care systems for patients in home settings, healthcare facilities, and social institutions through a unified dietary system that defines basic and specialized diets. Alternative nutrition methods are discussed separately, with enteral and parenteral nutrition serving as alternatives during unfavorable health conditions.

The authors focus on application techniques and complications associated with these methods. The book concludes with food safety considerations and foundational principles of the European Union’s food policy. Currently, dietetics and therapeutic nutrition form a critical component of professional training for healthcare students in both undergraduate and postgraduate education, for whom this textbook is designed.

Authors’ Collective

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Zuzana Mačeková - Zuzana Katreniaková a kol.

Demencia je jednou z naliehavých a mimoriadne zložitých globálnych výziev pre zdravotnícke a sociálne systémy 21. storočia. Na Slovensku sa počet osôb s demenciou odhaduje na 62 495 (2018), pričom sa predpokladá, že v roku 2040 tento počet vzrastie na 180 000. Demencie zatiaľ patria k nevyliečiteľným chronickým stavom, ktorým nie je možné úplne predchádzať. V roku 2024 (Livingston a kol.) bol publikovaný aktualizovaný model tzv. potenciálne ovplyvniteľných faktorov, ktoré môžu prispieť k zvýšenému riziku demencie. Patria k nim: nízka úroveň vzdelania, strata sluchu, vysoký LDL cholesterol, depresia, úrazové poranenie mozgu, fyzická nečinnosť, diabetes mellitus, fajčenie, vysoký krvný tlak, obezita, nadmerná konzumácia alkoholu, sociálna izolácia, znečistené ovzdušie (vrátane pasívneho fajčenia) a strata zraku. Týchto 14 rizikových faktorov predstavuje približne 45 % celosvetových demencií, ktorým by sa teoreticky dalo predísť. Napriek narastajúcej dostupnosti informácií, úroveň povedomia verejnosti o preventívnych prístupoch v správaní sa k sebe samým, ktoré môžu nástup demencie významne oddialiť, zostáva nízka. Farmaceuti na Slovensku majú v súčasnosti adekvátne kompetencie, aby vedeli pomôcť aj v oblasti prevencie demencií. Niekedy stačí poradenstvo priamo v lekárni, vo vážnejších prípadoch odporúčanie navštíviť lekára pre ďalšie posúdenie zdravotného stavu. Každopádne, človek takto nezostáva so svojim problémom sám a dostane včasnú a potrebnú zdravotnú starostlivosť.

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Alžbeta Blichárová - Ľudmila Verbóová - Zuzana Benetinová - Vladimír Tancoš  - Patrícia Kollárová  - Adam Nedoroščík - Erika Štammová  - Pavel Kočan

“Pathology Part 2 (summer semester) - Practical lessons for students of dental medicine” represents the second half of the university textbook designed for the pregradual study of pathology. The textbook complements the lectures of pathology and serves as a source of information for students of dental medicine, that are preparing for the practical credit, as well as the final oral examination.

In this part of the “Pathology” series, forty-four selected histopathological slides are presented. Each selected slide is provided with general information in relation to etiology and pathogenesis of the disease, as well as with corresponding morphological features, including the gross appearance and the most important histopathological characteristics. The textbook summarizes the basic concepts of systemic pathology (pathology of the heart, vessels, lungs, gastrointestinal, urogenital system, breast, musculoskeletal, nervous system, skin and infancy) and pathology of the orofacial region, that is logical continuation and completion of general pathology in the first semester.

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Sylvia Dražilová - Laura Gombošová - Martin Janičko - Ľubomír Skladaný - Eduard Veseliny

University textbooks are focused on undergraduate medical students and young doctors engaged in specialized training in gastroenterology, hepatology, and internal medicine.

The authors aimed to somewhat replace the lack of a concise and straightforward textbook on gastroenterology and hepatology for medical students, while also providing specific, directly applicable information for young doctors in inpatient departments caring for these patients.

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Magdaléna Hagovská - Alena Buková - Ľubomír Lachváč

Overweight as a risk factor for the development of civilization diseases and urogenital dysfunctions

Overweight and obesity represent a significant risk factor for the development of several diseases of civilisation, such as cardiovascular disease, type 2 diabetes mellitus and various forms of cancer. They also contribute significantly to urogenital dysfunctions such as urinary incontinence, overactive bladder and pelvic organ prolapse. Mechanisms that link excess weight to these dysfunctions include increased intra-abdominal pressure, hormonal changes, and chronic inflammatory processes that negatively affect the structure and function of the urogenital system. Prevention and treatment of overweight and obesity are therefore crucial not only in terms of reducing the risk of civilization diseases, but also in improving the quality of life through the prevention and treatment of urogenital dysfunctions.

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E-publication

Miriam Kozárová

Simulation-based medical education has become an integral part of medical education in the 21st century. It represents a modern and effective way to enable medical, nursing, emergency medicine, and other healthcare team members to safely develop clinical skills, decision-making abilities, and teamwork. Simulation-based medical education (SBME) is primarily about opportunities to try out and experience medical/nursing/rescue procedures in a safe environment without any risk to real patients.

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 Kvetoslava Rimárová 

The theme of the presented university textbook is a summary of selected basic knowledge of hygiene - environmental medicine. The script includes significant areas of environmental medicine as a science: the basics of environmental medicine, health and prevention issues of environmental health and risk assessment of potential exposure, the issue of air pollution, indoor pollution, problems of drinking water, the action of soil and solid waste, further issue of housing, nutrition and the impact of working conditions on health. Nutritional factors textbooks dealing with issues of rational nutrition, describe the individual components of nutrition, but also address the issue of food hygiene and the possibilities of foodborne infections. One chapter is also devoted to the impact of environmental conditions on health of children and youth. 

University textbook as a manuscript consists from 199 manuscript pages, is divided into 12 basic chapters, contains 36 citations in the literature.  In the Preface, the issue of categorization of diseases and define the basic concepts of health, prevention. Other chapters deal with the above selected chapters hygiene.

This university textbook comes as a basic university textbook for students of general  medicine in the English language, for students of bachelor's and master's studies  of medical schools - mainly bachelor's and master' program of  "Public health". Students of medicine and dentistry can also use these textbooks as an educational tool in the study of other subjects in the teaching of public health.

Autor

Vladimíra Tomečková

Nature, as well as the human body, contains an abundant quantity of organic molecules. This textbook describes selected oxygen, sulfur, nitrogen derivatives of hydrocarbons, heterocyclic compounds of their reactions, which are important in the human body or are found in pharmaceutical active substances, poisons, foodstuffs and heat-treated food. The last part of the textbook describes the isomerism of organic compounds, which enables dynamic changes in the structure of molecules that have different properties. Nature is filled with different plants and animals and is the first laboratory to produce bioactive organic natural compounds. These compounds are compatible with human cells and are applicable as therapeutic medicine. There is an effort to reproduce natural molecules in chemical laboratories, but they cannot be as perfect as the natural ones. Synthetic molecules can serve as a model for multiple studies, but there still does not exist a magic panacea pill or a perfect copy of nature, for the treatment of various diseases. Knowledge about the regenerative and toxic effect of medicinal substances in dependence on their structure (type and number of substituents) is very important for the understanding of their role in modulation of health and disease in dependence on their concentration. Compounds can be used daily only in recommended doses (higher doses can be toxic), but still will not replace a healthy diet. People need a varied diet to be healthy, in which are all necessary nutrients, what Hippocrates demonstrated long ago “Let food be the medicine, and let medicine be the food.” This book is written for students who select bioorganic chemistry subject during the study of general medicine or dentistry as well as for motivated students who would like to practice their knowledge and wish to improve in this subject and for students who would like to learn simplified basic organic reactions with their future application in biochemistry. Learn the simple models mainly through creative simple instruction by using different colours, by repetition, practice by drawing of formulas by hand (at least three times) and memorization of common names of compounds and their reactions which have application in biochemistry. Thus, establishing simple educational methods how to distinguish organic molecules according to the colours of a functional group can promote universal learning for all students who thought that chemistry is a difficult subject, but hopefully they change their opinion after study of this book.

Keywords: organic molecules, oxygen, sulfur, nitrogen derivatives of hydrocarbons, heterocyclic compounds, chemical reactions, isomerism of organic compounds

E-book

Renáta Suchanová - Lucia Dimunová

The following textbook deals with issues related to communication in medical practice which significantly affects the survival and behaviour of a patient. Communication skills and the attitude of healthcare professionals exercised towards a patient have significant impact on patient’s ability to handle treatment and his or hers co-operation during the process.

This publication is intended to serve as a guide applicable towards deeper knowledge, better comprehension and overall understanding of the mental state of an ill person, his or her needs, stances, behaviour patterns, but also his or her management of the illness. Attention is also paid to the active building of a relationship between the healthcare professional and the patient, with emphasis on respect, truthfulness, and mutual understanding in communication. Particularly accentuated are issues related to specific effective communication skills, methods, and techniques serviceable during interactions with a patient; application of empathy and proactive approach are highlighted.

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Ingrid Hodorová a kolektív

                Vysokoškolská učebnica „Ultrasonografická anatómia 1“ je určená predovšetkým študentom lekárskych fakúlt. Publikácia dopĺňa medzeru na medicínskom literárnom trhu, na ktorom takýto druh literatúry doteraz absentuje. V učebnici sa čitateľ oboznámi s koreláciou anatomického a ultrasonografického obrazu orgánov a štruktúr za fyziologického stavu. Táto korelácia poukazuje na úzke prepojenie teoretického predmetu anatómia s klinickou praxou s ultrasonografickým vyšetrením, ktoré je dnes neoddeliteľnou súčasťou základných vyšetrovacích metód v mnohých medicínskych odboroch.

                Učebnica pozostáva z anatomickej časti, ktorá sa venuje základnému anatomickému popisu jednotlivých orgánov brucha a panvy. Nosnou časťou učebnice je sonografická časť, ktorá popisuje a charakterizuje jednotlivé ultrasonografické snímky. Čitateľ môže priamo porovnať vzhľad a prípadné rozdiely orgánov a štruktúr získaných dvomi úplne odlišnými zobrazeniami.

                Veríme, že nová vysokoškolská učebnica splní očakávania študentov, ako aj všetkých tých, pre ktorých je oblasť ultrasonografického zobrazenia z pohľadu anatóma predmetom záujmu – bude tak prospešná nielen pre anatómov, ale aj pre začínajúcich sonografistov.

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Ján Mojžiš - Ladislav Mirossay -Andrej Miroššay (eds.)

This long-standing scientific conference continues its tradition of fostering collaboration, sharing knowledge, and supporting progress in the fields of pharmacology, pharmacy, toxicology, and biomedical sciences. The 2025 meeting brings together distinguished researchers, clinicians, educators, and students from the Czech Republic, Slovakia, and beyond, united by a common goal—to advance our understanding of pharmacological science and improve human health.

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Eva Ďurovcová - Mária Mareková

Clinical Biochemistry - selected chapters - MEFANET >>> 

After 7 years, we finally reworked the textbook on the subject of clinical biochemistry at UPJŠ FM in Košice. We have innovated information in accordance with recommendations of professional medical societies and added new chapters. As the scope of the subject is limited, the textbook does not cover all issues of biochemical diagnostics. It focuses on disorders of water-ion and acid-base balance disorders, and basic laboratory diagnostics of diseases of selected organs.

The textbook of clinical biochemistry has the ambition to become a practical aid for senior medical students and beginning doctors in the study of laboratory medicine. It should make it easier for them to orientate themselves in routinely used clinical-biochemical examinations and could form a springboard for a more detailed studying of laboratory methods and their use in diagnostic and monitoring algorithms.
Like any medical discipline, clinical biochemistry is evolving rapidly and gradually integrating with other areas of laboratory medicine. New diagnostic methods penetrate deeper into the essence of the biochemical mechanisms of the human body, and "omic" methods are gaining ground. It is almost sure that in a few years, laboratory examination looks quite different from today. If this publication quite hypothetically reaches its next edition, many chapters will need to updated, and new chapters written following the up-to-date status.
Authors thanks to their colleagues and reviewers for their professional comments and constructive criticism of the text - prof. Jaroslav Racek, MD, DrSc. from FM UK in Pilsen.
Authors thanks very kindly too prof. MUDr. Dušan Dobrota, CSc. (JFM UK Martin) and doc. MVDr. Zuzana Kostecká, PhD. (UVMP, Košice), who read and wrote review of this textbook.

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