Anestéziológia a intenzívna medicína

Marek Šoltés - Jozef Radoňak

Laparoskopická chirurgia dnes predstavuje štandardnú a v mnohých ohľadoch preferovanú modalitu chirurgickej liečby. Dynamika jej celosvetového rozšírenia, umožnená pokrokom v biomedicínskych technológiách a rozvojom globálnych informačných a komunikačných kanálov, nemá v histórii chirurgie obdobu. V súčasnosti už prakticky neexistuje žiadna brušná operácia, ktorá by sa nevykonávala laparoskopickým spôsobom, pričom v mnohých prípadoch je už laparoskopický postup metódou voľby.

Napriek, a možno práve vďaka bezprecedentne rýchlej penetrácii laparoskopických operácií do každodennej chirurgickej praxe naďalej v mnohých ohľadoch absentujú všeobecne akceptované technické štandardy. Vysoká variabilita procesných postupov v rámci jednotlivých laparoskopických operácií vychádza skôr zo zvyklostí daného pracoviska ako z medicíny založenej na dôkazoch. Táto situácia je ďalej modifi kovaná rozvojom nových a staronových koncepcií charakteru minilaparoskopie, SILS či NOTES a ich hybridných kombinácií s klasickou laparoskopiou.

Cieľom monografi e je pritiahnuť pozornosť odbornej verejnosti späť k základným princípom laparoskopickej chirurgie, ktoré by mali byť základňou pre efektívne a bezpečné vykonávanie laparoskopických operácií, ako aj bázou pre kritický postoj k módnym inovatívnym trendom. Obsahovo sa sústredí skôr na všeobecne menej známe a v našich podmienkach zriedkavo diskutované témy, ktorých význam sa hlbšie analyzoval len v nedávnej minulosti. Našou ambíciou bolo vytvoriť vyvážený materiál, ktorý by bol zaujímavým primárnym informačným zdrojom nielen pre lekárov špecialistov, ale aj pre poslucháčov lekárskych fakúlt a kolegov v špecializačnej príprave v chirurgických odboroch.

Autori

E-publication

Beáta Grešš HalászMária Sováriová SoósováMartin ČervenýJana Michalková

The aim of this university textbook is to provide a systematically structured teaching text focused on research in health sciences and, at the same time, to offer a practical methodological manual for writing final theses intended for students of medical and non-medical fields of study. The first chapter introduces the topic, maps the historical development of research in medical and non-medical sciences, and explains the concept of evidence-based practice (EBP) in the context of research activities. It also highlights the importance of research for these fields and describes the individual steps, principles, and methodological procedures of scientific work. The second chapter focuses on the basic attributes of research in health sciences, with an emphasis on key definitions, basic research designs, the typology of scientific studies, and the possibilities for using the relevant methodologies. It also includes the interpretation and analytical processing of quantitative data, while the third chapter analogously elaborates on the qualitative research approach. The fourth chapter is devoted to the ethical aspects of scientific research. The fifth chapter focuses on the evaluation of research papers in terms of their quality, structure, content coherence, reliability, and validity. The final sixth chapter provides methodological guidelines for planning, implementing, and processing individual types of final theses, with the aim of offering students practical and clearly structured instructions for their preparation. The publication also includes questions, tasks, and exercises that supplement theoretical knowledge with practical examples. These cases are intended to develop students' ability to design research studies and methodologically correctly prepare final theses.

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Vladimíra Tomečková

Nature, as well as the human body, contains an abundant quantity of organic molecules. This textbook describes selected oxygen, sulfur, nitrogen derivatives of hydrocarbons, heterocyclic compounds of their reactions, which are important in the human body or are found in pharmaceutical active substances, poisons, foodstuffs and heat-treated food. The last part of the textbook describes the isomerism of organic compounds, which enables dynamic changes in the structure of molecules that have different properties. Nature is filled with different plants and animals and is the first laboratory to produce bioactive organic natural compounds. These compounds are compatible with human cells and are applicable as therapeutic medicine. There is an effort to reproduce natural molecules in chemical laboratories, but they cannot be as perfect as the natural ones. Synthetic molecules can serve as a model for multiple studies, but there still does not exist a magic panacea pill or a perfect copy of nature, for the treatment of various diseases. Knowledge about the regenerative and toxic effect of medicinal substances in dependence on their structure (type and number of substituents) is very important for the understanding of their role in modulation of health and disease in dependence on their concentration. Compounds can be used daily only in recommended doses (higher doses can be toxic), but still will not replace a healthy diet. People need a varied diet to be healthy, in which are all necessary nutrients, what Hippocrates demonstrated long ago “Let food be the medicine, and let medicine be the food.” This book is written for students who select bioorganic chemistry subject during the study of general medicine or dentistry as well as for motivated students who would like to practice their knowledge and wish to improve in this subject and for students who would like to learn simplified basic organic reactions with their future application in biochemistry. Learn the simple models mainly through creative simple instruction by using different colours, by repetition, practice by drawing of formulas by hand (at least three times) and memorization of common names of compounds and their reactions which have application in biochemistry. Thus, establishing simple educational methods how to distinguish organic molecules according to the colours of a functional group can promote universal learning for all students who thought that chemistry is a difficult subject, but hopefully they change their opinion after study of this book.

Keywords: organic molecules, oxygen, sulfur, nitrogen derivatives of hydrocarbons, heterocyclic compounds, chemical reactions, isomerism of organic compounds

E-book

Iveta Domoráková - Štefan Tóth - Zuzana Fagová - Eva Mechírová - Alexandra Kunová - Kristína Čurgali - Viera Eliášová - Monika Holodová - Marianna Danková

In our new electronic textbook, FUNDAMENTALS OF HISTOLOGY II – Textbook and Atlas of Microscopic Anatomy of Organs, we present students and the professional public with essential information about the microscopic structure of organs, accompanied by extensive visual documentation of organ structures and clear legends for the microphotographs.

All histological specimens come from the archive of the Institute of Histology and Embryology, are used in practical exercises, and are also included in teaching presentations. The electronic textbook is intended for undergraduate and postgraduate students of general medicine and dentistry at medical faculties, as well as for students of veterinary medicine and pharmacy, and biology students at faculties of natural sciences.

The textbook is designed so that students can find clear explanations of most medical terms and also reinforce their knowledge of professional terminology in Latin. An advantage of the electronic textbook is the ability to enlarge microscopic photographs, allowing detailed observation of structures without any qualitative loss of the viewed image. The microphotographs used in the atlas were taken with the following equipment: Zeiss Promicra and Olympus BX50 with a Canon EOS 2000D digital camera and QP Industrial 3.2 software.

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Miroslav Gajdoš - Igor J.Šulla a kol. 

Učebnica pre lekárov a študentov všeobecného lekárstva

Medicína je neprestajne sa vyvíjajúca vedná disciplína. Základný výskum v spojení s klinickou praxou rozširujú súčasné vedomosti, čo sa veľmi výrazne prejavuje aj v neurovedách, v praktickej podobe hlavne v neurofyziológii, neurofarmakológii, neurológii, diagnostickej aj intervenčnej neurorádiológii a v neurochirurgii. V priebehu ostatných troch desaťročí neurovedy prekonali pozoruhodný vývoj. Podnietili ho potreby praxe a umožnilo využitie poznatkov biológie, chémie, biochémie, aplikovanej matematiky, výpočtovej techniky a fyzikálnych objavov realizovaných v moderných prístrojoch i liečebných postupoch. To všetko podstatne uľahčilo, spresnilo a urýchlilo diagnostiku ochorení nervového systému, umožnilo relatívne bezpečné chirurgické zásahy na štruktúrach v minulosti nedostupných a otvorilo nové perspektívy, hlavne v oblasti reparácie poškodených tkanív, respektíve ich funkcií autotransplantáciou kmeňových/progenitorových buniek, terapeutickými zásahmi na genómovej, prípadne proteómovej úrovni. Ako vysokoškolskí učitelia sa každodenne stretávame nielen s mimoriadnym záujmom študentov i zdravotníckych pracovníkov o nové poznatky, ale aj s určitou neistotou pri posudzovaní možností, ktoré jednotlivé disciplíny patriace do skupiny neurovied ponúkajú. Jednou z príčin spomenutého javu je pravdepodobne časový faktor, keď najnovšie poznatky ešte nestačili preniknúť do odbornej literatúry, alebo v nej nie sú dostatočne zdôraznené. Druhou príčinou môže byť pomerne malá skúsenosť s niektorými ochoreniami nervového systému, ktoré sa síce vyskytujú zriedkavejšie, ale ich následky sú závažné. Cieľ, ktorý sme sledovali napísaním tejto učebnice, bolo aspoň čiastočne odstrániť spomenuté nedostatky všetkých odborných publikácií.

Počas prípravy rukopisu sme sa snažili, aby terapeutické postupy, názvy liekov a ich dávkovanie boli v súlade s najnovšími poznatkami vedy a klinickej praxe. Oprávnene však môžeme predpokladať, že budúce objavy zmenia súčasný pohľad na problematiku diagnostiky aj liečby ochorení nervového systému.

Vysokoškolská učebnica je určená študentom všeobecného lekárstva UPJŠ Lekárskej fakulty v Košiciach a lekárom, zameraným hlavne na všeobecné lekárstvo.

Kolektív autorov

Radoslav Morochovič - Rastislav Burda -

Ľuboš Tomčovčík - Peter Cibur - Štefan Ivanecký

Vysokoškolský učebný text určený pre študentov všeobecného lekárstva, zubného lekárstva a fyzioterapie, ktorý obsahuje podstatné časti z predmetu úrazová chirurgia potrebných na zvládnutie vysokoškolského štúdia.

E-book

Silvia Danková - Lucia Dimunová - Beáta Grešš Halász - Jana Sušinková

The present multimedia university textbook is intended for students of the bachelor's degree programme in nursing, not excluding both medical and nursing degree courses.

The purpose of the present publication is to provide a comprehensive view of the nature of surgical nursing, focusing on the method of providing nursing care - the nursing process. It comprehensively describes the individual steps of perioperative nursing care and the subsequent possible complications associated with surgical procedures. Documents the depth of knowledge and skills training in chronic wound care management issues. Respects the culture of patient and healthcare professional safety.

The college textbook uses e-learning methods in combination with traditional face-to-face education. Based on the latest resources, it respects the concept of health care delivery and professional training of nurses.

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E-book

Ján Kučera - Eva Kovaľová - Juraj Strecha

Peri-implantation diseases such as peri-implantitis and mucositis have a wide range of prevalence. Several etiological factors and the interaction of risk factors influence their onset and development. Careful investigation determines the diagnosis and subsequent treatment. Treatment, depending on the condition, is either non-surgical or surgical. Systematic postoperative care, a recall system, and patient instruction and cooperation are essential, which create the preconditions for successful implant treatment.

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E-book

Miriam Kozárová

The publication "News in Diabetology and Lipidology" focuses on extremely relevant topics in diabetology and lipidology, reflecting the state of these issues in light of the recommendations from professional societies from 2019. In diabetology, it primarily addresses the intensification of antidiabetic treatment using modern drug classes—specifically, incretin enhancers and sodium-glucose cotransporter-2 (SGLT-2) inhibitors (gliflozins). Few medical fields have experienced such a development of new pharmacological options as diabetology has in the last two decades. While pharmacotherapy for type 2 diabetes (DM2) was limited to the use of biguanides, sulfonylurea derivatives, and insulin throughout the second half of the last century, recent years have introduced entirely new groups of oral antidiabetics with cardio- and nephroprotective effects. In lipidology, it pertains to the new recommendations from the European Atherosclerosis Society (EAS) with new treatment goals for serum lipids and lipoproteins, including the use of biological therapies.

This textbook is primarily intended for medical students in doctoral studies and doctoral candidates, as well as for physicians preparing for specialization exams in internal medicine, endocrinology, diabetology, metabolic disorders and nutrition, as well as cardiology and angiology. I believe that readers will find information in this publication that will aid them in their studies and translate into their daily clinical practice.

Author

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Alžbeta Blichárová a kolektív

“Pathology Part 1 (winter semester) - Practical lessons for students of general medicine” represents the first half of the university textbook designed for the pregradual study of pathology. The textbook complements the lectures of pathology and serves as a source of information for students of general medicine, that are preparing for the practical as well as the final oral examination.

In this part of the “Pathology” series, seventy selected histopathological slides are presented. Each selected slide is provided with general information in relation to etiology and pathogenesis of the disease, as well as with corresponding morphological features, including the gross appearance and the most important histopathological characteristics. The textbook summarizes the basic concepts of general pathology that are necessary to master the broad field of systemic pathology in the second semester.

Keywords: general pathology – histopathological slides – general medicine – gross appearance – microscopic image

Vincent Nagy

Predkladaná monografia sa komplexne venuje problematike urolitiázy. Má 19 kapitol, ktoré zahrňujú celú šírku problematiky urolitiázy a to epidemiológiu, etiológiu, typy konkrementov, osobitné situácie pri urolitiáze, diagnostiku urolitiázy, zobrazovacie vyšetrovacie metódy pri urolitiáze, konzervatívnu liečbu urolitiázy, chirurgické a endoskopické metódy liečby urolitiázy, metafylaxiu konkrementov a konkrementy v močovom mechúri. V monografii sa zdôrazňuje význam individuálneho rozhodovania o optimálnom spôsobe liečby. Do úvahy sa berie veľkosť konkrementov, ich počet, lokalizácia, anatomické predpoklady a röntgenologické charakteristiky. Pri plánovaní aktívnej liečby sa zdôrazňuje význam resp. potreba zobrazovacími metódami vyšetriť aj anatómiu vývodných močových ciest. Nezastupiteľné miesto, najmä v prípadoch viacpočetnej a opakujúcej sa urolitiázy a geneticky podmienenej urolitiázy, má kompletné metabolické vyšetrenie. Dokumentuje všetky moderné spôsoby diagnostiky a liečby urolitázy. Metodicky opisuje liečbu urolitiázy – akútny management pri renálnej kolike, pri urosepse pri konkrementom zablokovanej obličke a v tehotenstve. Prevažná väčšina pacientov s urolitiázou je liečená farmakologicky a semininvazívnymi technikami. Vychádza sa z vlastných skúseností, komentuje využitie extrakorporálnej litotripsie, endoskopických metód, stentov. Monografia venuje pozornosť aj auxiliárnym metódam, ktoré sa používajú v liečbe urolitiázy, liečbe sprievodnej infekcie, poranení obličiek a močových ciest, poranení okolitých orgánov, rôznych spôsobov derivácie moču, krvácania. V závere sú spomenuté kalcifikácie pri obličkových tumoroch.

Autor

E-book

Jaroslav Majerník - Andrea Kačmariková

The university textbook "Databases in MS Access - accompanying texts for practical exercises" is intended for students of medical faculties, students of non-technical universities and all beginners in working with databases. It introduces the reader to the issue of database data processing and explains the basic principles that need to be known when creating relational databases. It is therefore suitable for those who have not yet worked with databases, or who have started thinking about managing their data using their own database.

However, even more "experienced" computer users can find useful information here. The university textbook is written in the way that its content can be mastered with basic knowledge of working with computers and programs running in the environment of MS Windows operating system.

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E-book

Jana Mašlanková

Colorectal carcinoma is the most common malignant tumor of the digestive system, and its rising incidence in Slovakia—particularly among the male population—is alarming. Although significant progress has been made in the diagnosis, screening, and treatment of patients with advanced colorectal cancer, therapeutic options remain limited, necessitating the discovery of additional markers to serve as prognostic predictors.

This monograph aims to draw the attention of the professional community to the critical role and significance of the TGF-β signaling pathway in the initiation, progression, and treatment of colorectal carcinoma. A substantial portion of the text focuses on lesser-known emerging trends and ongoing clinical trials for colorectal cancer patients.

The monograph aspires to provide a balanced resource that serves as an engaging informational tool not only for specialist physicians but also for medical faculty students. By integrating novel insights and clinical data, it seeks to bridge gaps in current understanding and highlight potential avenues for future research and therapy.

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E-book

Sylvia Dražilová - Laura Gombošová - Martin Janičko - Ľubomír Skladaný - Eduard Veseliny

University textbooks are focused on undergraduate medical students and young doctors engaged in specialized training in gastroenterology, hepatology, and internal medicine.

The authors aimed to somewhat replace the lack of a concise and straightforward textbook on gastroenterology and hepatology for medical students, while also providing specific, directly applicable information for young doctors in inpatient departments caring for these patients.

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Jozef Radoňak a kol.

Skriptá chirurgická propedeutika predstavujú učebné texty prinášajúce pohl'ad do histórie chirurgie cez všeobecne platné princípy chirurgie, moderné diagnostické a terapeutické metó­dy. Patričná pozornost' sa venuje základom chirurgickej onkológie, úrazovej chirurgie, anesteziológie a resuscitácie ako aj liečbe krvácania, infekcie, šoku či transplantáciám. Súčas­ťou textu sú aj kapitoly z vojnovej chirurgie.

E-book

Kvetoslava Rimárová

This manual is published as an auxiliary methodological script for students of bachelor and master courses of medical faculties - especially bachelor and master courses of ‘Public Health’.

Students of general medicine and dentistry can also use these teaching texts as an educational aid when studying the subject “Hygiene”, which is taught either on its own or as part of broader subjects, e.g. “Public Health”. 

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