Vybrané kapitoly z gerontológie a geriatrie. I.diel: Geriatrické syndrómy

E-book

Jana Mašlanková

Colorectal carcinoma is the most common malignant tumor of the digestive system, and its rising incidence in Slovakia—particularly among the male population—is alarming. Although significant progress has been made in the diagnosis, screening, and treatment of patients with advanced colorectal cancer, therapeutic options remain limited, necessitating the discovery of additional markers to serve as prognostic predictors.

This monograph aims to draw the attention of the professional community to the critical role and significance of the TGF-β signaling pathway in the initiation, progression, and treatment of colorectal carcinoma. A substantial portion of the text focuses on lesser-known emerging trends and ongoing clinical trials for colorectal cancer patients.

The monograph aspires to provide a balanced resource that serves as an engaging informational tool not only for specialist physicians but also for medical faculty students. By integrating novel insights and clinical data, it seeks to bridge gaps in current understanding and highlight potential avenues for future research and therapy.

Download the e-book for free (pdf)

Slavomír Perečinský - Ľubomír Legáth - Lenka Murínová - Marek Varga

Vysokoškolské učebné texty sú zamerané na najčastejších profesionálnych respiračných ochorení, ktoré sú na Slovensku i v ostatných krajinách Európskej únie treťou najčastejšou skupinou ochorení súvisiacich s pracovnou expozíciou. Poškodenie dýchacieho traktu môže mať prechodný, ale aj trvalý a často klinicky a prognosticky závažný charakter. Publikácia sa venuje základným skupinám ochorení – intersticiálne ochorenia pľúc, alergické ochorenia a nádorové ochorenia.  Jednotlivé kapitoly podrobne približujú etiopatogenézu ochorení, klinický obraz, diagnostické metódy a diferenciálnu diagnostiku. Záverečná kapitola upriamuje pozornosť na vyšetrovacie metódy v pracovnom lekárstve. V jej prvej časti sú rozpracované funkčné vyšetrovacie metódy dýchacieho systému. Druhá časť sa venuje zobrazovacím vyšetrovacím metódam s názornou obrazovou dokumentáciou najčastejšie hlásených pneumokonióz.

E-book

Lucia Bosáková - Zuzana Dankulincová - Daniela Fiľakovská

Publication called Scientific communication and management of research projects serves as background and teaching material. Its aim is to help university students and researchers develop competencies important for scientific work, such as scientific integrity, critical work with literary sources, management of research projects and scientific communication. Publication is divided into four parts.

The first part is focused on the preparation of a research project, where it is important to know the basic ethical principles applied in the research project, but also to be able to critically assess literary sources and process them. In the second part, it provides information on the preparation of research projects and their management, including their financing, from preparation and planning, through initialization to implementation, management, logistics, monitoring, evaluation and termination. The third part pays attention to the preparation, processing and presentation of scientific results in the form of a scientific article, presentation, poster or press release, thus covering not only a professional but also a lay audience.

The final fourth part provides information about communication with a scientific journal, whether it is the process of sending, revising an article up to its publication, or the process of assessing scientific work by scientific journal editors in the process of screening and peer review.

Download the e-book for free (pdf)

 Eva Ďurovcová - Mária Mareková 

The presented textbook is intended for students of general medicine and should support their knowledge about indication and interpretation of basic biochemical tests. Clinical biochemistry continues to be one of the most rapidly advancing areas of laboratory medicine, which in line with using of modern technology more and more emphasizes the evidence-based medicine in order to improve diagnosis and monitoring of patients. Selected topics have an ambition to outline and explain the most common issues of biochemical diagnosis of in internal medicine. Individual chapters are devoted to disorders of water, electrolyte and acid-base balance, kidney and liver disease, diabetes mellitus, and biomarkers used in the diagnosis of cardiac necrosis and heart failure. Given the limited range, the textbook merely summarizes the basic knowledge that students have obtained during the study of other subjects, such as medical biochemistry, pathophysiology and internal medicine, and emphasis is given to laboratory diagnosis in accordance with the newer guidelines of professional societies. We hope that the textbook will be helpful in the study of clinical subjects and encourage students' interest in laboratory medicine.

Authors

Alžbeta Blichárová a kolektív

“Pathology Part 1 (winter semester) - Practical lessons for students of general medicine” represents the first half of the university textbook designed for the pregradual study of pathology. The textbook complements the lectures of pathology and serves as a source of information for students of general medicine, that are preparing for the practical as well as the final oral examination.

In this part of the “Pathology” series, seventy selected histopathological slides are presented. Each selected slide is provided with general information in relation to etiology and pathogenesis of the disease, as well as with corresponding morphological features, including the gross appearance and the most important histopathological characteristics. The textbook summarizes the basic concepts of general pathology that are necessary to master the broad field of systemic pathology in the second semester.

Keywords: general pathology – histopathological slides – general medicine – gross appearance – microscopic image

E-book

Tomáš Toporcer - Adrián Kolesár

The textbook "Heart surgery for medics" was created in response to repeated requests from students of the Faculty of Medicine P.J.Šafárik University, for the surgery state exam study material. In terms of content, the text corresponds to the required knowledges in cardiac surgery, needed to pass the state exam in surgery. Orientation in the issue of cardiac surgery is not only necessary for students whose specialization will be closely related to the given field. Basic knowledge of cardiac surgery is necessary for every medical faculty graduate. Knowing the treatment options, but also the possible complications of individual cardiac surgical procedures, is necessary for most medical specialties. Only by mastering the basics of each medical field can the patient be properly, adequately and modernly managed.

Download the e-book for free  (pdf)

 Ingrid Dravecká 

College textbook "Investigation methods in Diabetology" is designed for students of medicine. It can help them in preparing for an exam from internal medicine but specially in preparing for a state exam from internal medicine. The introduction is devoted to classification and diagnostic criteria of diabetes mellitus. Further It describes investigation options (clinical, laboratory, imaging) of different types of diabetes mellitus as well as its acute and chronic complications. At the end there are given diagnostics and classification of the individual components of the metabolic syndrome, obesity and dyslipidemia.

Author

E-book

Iveta Domoráková et al.

The e-learning textbook is available at: https://portal.lf.upjs.sk. The textbook contains 11 chapters focusing on the microscopic anatomy of the head and neck region, with an emphasis on the oral and nasal cavities, skull bones and their development, and the detailed microscopic structure of teeth and their development. One chapter is dedicated to dentition from the perspective of the clinical significance of understanding tooth structure and development. The textbook includes chapters on the microscopic anatomy of organs that are functionally important for the head region, such as the vascular, lymphatic, endocrine, and nervous systems. The textbook is linked to an atlas, has a total of 490 pages, and features 300 original microphotographs using common histological stains, histochemical, immunohistochemical, and impregnation methods.

The textbook was created with the support of the KEGA project 019UPJŠ-4/2016.

Download it from the Mefanet portal (pdf)

E-book

Ján Mojžiš - Ladislav Mirossay -Andrej Miroššay (eds.)

This long-standing scientific conference continues its tradition of fostering collaboration, sharing knowledge, and supporting progress in the fields of pharmacology, pharmacy, toxicology, and biomedical sciences. The 2025 meeting brings together distinguished researchers, clinicians, educators, and students from the Czech Republic, Slovakia, and beyond, united by a common goal—to advance our understanding of pharmacological science and improve human health.

Download the e-book for free (pdf)

E-book

Tatiana Kimáková - Vladimír Pavlík

The scientific monograph focuses on the characteristics of free radicals, reactive oxygen and nitrogen species, oxidative stress, and its impact on various diseases. A significant portion is dedicated to antioxidants, their classification based on multiple criteria, the characteristics of selected antioxidants in terms of their functions, manifestations of their deficiency and excess, and the overall antioxidant capacity of the body.

A special section is devoted to enzyme-based antioxidants, natural sources of antioxidants in the form of vitamins, trace elements, flavonoids, polyphenols, and coenzyme Q10. To provide a clearer understanding of antioxidants and their influence on population health, the monograph presents results from a research project included in the program "Research Support for Enhancing the Defense Capabilities of the Czech Republic in NATO Structures."

The research was conducted between 2010 and 2012 as part of preventive rehabilitation programs for professional soldiers with a sports component. The study involved 218 professional soldiers, including 180 men and 38 women, with an average age of 33.3 years. The current health status and dietary habits of the soldiers were assessed using questionnaires.

The study described the saturation of the observed group with antioxidant vitamins and statistically evaluated the relationship between their levels and the risk indicators for the development of cardiovascular diseases. Individual analyses were performed using the Reflotron device calibrated with Reflotron Precinorm control serum. Following blood collection, all participants underwent anthropometric examinations (body weight, height, waist circumference), blood pressure measurements, heart rate monitoring, and physical fitness assessments through simple functional tests.

This scientific monograph is suitable for the scientific community, students of medical, veterinary, and natural sciences, as well as public health students at all levels of university education. It is also intended for informed members of the public.

Authors

Download the e-book for free (pdf)

Mária Mareková a kol.

Predkladaná vysokoškolská učebnica predstavuje základy biochémie a je určená predovšetkým pre bakalárske  študijné programy (napr. ošetrovateľstvo, fyzioterapia, verejné zdravotníctvo). Vysokoškolská učebnica predstavuje zjednodušenú alternatívu lekárskej biochémie a je svojím obsahom aj rozsahom vhodná pre študentov nelekárskych študijných odborov. Okrem priblíženia základných metabolických dejov prebiehajúcich v organizme človeka, ponúka aj stručný prehľad klinicko-biochemických parametrov štandardne vyšetrovaných pri podozrení na ich poruchy. Snaží sa poskytnúť študentom, predovšetkým zdravotníckych študijných programov, základy lekárskej a klinickej biochémie a oboznámiť ich s najčastejšie používanými metódami v biochemickom laboratóriu v primeranom rozsahu. Chce prispieť k prehĺbeniu vedomostí o metabolizme zdravého, ale i chorého človeka, resp. o klinicko-biochemických diagnostických postupoch a laboratórnych vyšetreniach a vzbudiť záujem o ďalšie vzdelávanie. Budeme radi, ak poslúži nielen ako príprava na skúšku, ale bude inšpiráciou napr. pre realizáciu diplomových prác zameraných na vedecko-výskumnú oblasť klinickej biochémie či laboratórnej medicíny. 

Autorky

E-book

Jaroslav Majerník - Andrea Kačmariková

The university textbook "Databases in MS Access - accompanying texts for practical exercises" is intended for students of medical faculties, students of non-technical universities and all beginners in working with databases. It introduces the reader to the issue of database data processing and explains the basic principles that need to be known when creating relational databases. It is therefore suitable for those who have not yet worked with databases, or who have started thinking about managing their data using their own database.

However, even more "experienced" computer users can find useful information here. The university textbook is written in the way that its content can be mastered with basic knowledge of working with computers and programs running in the environment of MS Windows operating system.

Download the e-book for free (pdf)

E-book

Nikita Bobrova kol.

The concept of medical ethics is interpreted as both applied and professional ethics. As a bioethical discipline, it consists of three normative parts: biogenesis, biotherapy, and thanatology. From an ethical perspective, medicine is part of clinical bioethics; however, at the current stage, “evidence-based ethics” is still lacking.

In the context of standardizing health care, there is an excessive development of certain components of bioethics (such as ethical codes and the concept of patient autonomy), but also a reduction, especially of its clinical component (such as communication, thanatology, euthanasia, dysthanasia, and futile treatment). Current legislative efforts are leading to a reduction in the rights of health care workers, particularly in terms of corporate autonomy.

The fundamental task of medical ethics is the cultivation of medical professionalism, which is defined as the professional alignment of expert, ethical, and legal reasoning, and as a starting point for thinking in terms of values, with reflection on the bioethical space in clinical and professional practice.

Since society declares health as its priority, this priority should positively influence the entire health care system, and its basic idea should be a health care system based on a humanistic ethical paradigm with social and professional application.

Download the e-book for free (pdf)

E-book

Lucia Dimunová - Jana Michalková - Gabriela Štefková - Mária Zamboriová

Following innovative trends in university education, this academic textbook offers guidance to update and make the educational process more attractive for all healthcare professions. It applies critical thinking and strategic method of concept mapping in teaching, which are suitable tools for the facilitator and the educant to achieve the desired goal. Critical thinking is an essential academic skill upon which other knowledge and intellectual virtues can be built. It is also an essential equipment for every graduate of the healthcare profession.

The textbook is complemented by a chapter focusing on methods for structural and formative assessment of learning outcomes. The publication is also enriched with sample digital concept maps of which cognitive content can be edited and graphically modified.

The aim of this academic textbook is to present a way of acquiring knowledge through critical thinking using concept mapping as a method, with the final goal of implementing the acquired knowledge into everyday practice.

Download e-book for free (pdf)

František Sabola kol.

Although we are not really sure if “Love is coming from the Heart” and nor we know where “the Residence of Soul” is, we are still overwhelmed by its unprecedented effort to keep us alive. Our lives are nowadays fulfilled with enormous chances to satisfy our needs and wishes. Hand in hand is changing our way of life, the intake of calories is growing and the amount of physical activity decreasing. We live longer and maybe happier but our hearts
and vessels are like mirrors showing us how we live. Diseases of the Heart and vessels have become the number one cause of death in highly developed countries including our homeland.
Prevention of cardiovascular diseases has become and an important social and health care system issue. The knowledge requirement of basic principles of cardiology and heart surgery is increasing. Without an understanding of basic principles a good clinical practice is hardly possible.
Together with my Colleagues of Heart surgery department of VÚSCH and LF UPJŠ we prepared this short overview of basic knowledge about surgery of the human heart. We hope that reading it will be more an adventure than a painful journey. If you find some answers to your unanswered questions our effort was not a waste of time.

Authors

E-book

Jana Mašlanková

Colorectal carcinoma is the most common malignant tumor of the digestive system, and its rising incidence in Slovakia—particularly among the male population—is alarming. Although significant progress has been made in the diagnosis, screening, and treatment of patients with advanced colorectal cancer, therapeutic options remain limited, necessitating the discovery of additional markers to serve as prognostic predictors.

This monograph aims to draw the attention of the professional community to the critical role and significance of the TGF-β signaling pathway in the initiation, progression, and treatment of colorectal carcinoma. A substantial portion of the text focuses on lesser-known emerging trends and ongoing clinical trials for colorectal cancer patients.

The monograph aspires to provide a balanced resource that serves as an engaging informational tool not only for specialist physicians but also for medical faculty students. By integrating novel insights and clinical data, it seeks to bridge gaps in current understanding and highlight potential avenues for future research and therapy.

Download the e-book for free (pdf)

Slavomír Perečinský - Ľubomír Legáth - Lenka Murínová - Marek Varga

Vysokoškolské učebné texty sú zamerané na najčastejších profesionálnych respiračných ochorení, ktoré sú na Slovensku i v ostatných krajinách Európskej únie treťou najčastejšou skupinou ochorení súvisiacich s pracovnou expozíciou. Poškodenie dýchacieho traktu môže mať prechodný, ale aj trvalý a často klinicky a prognosticky závažný charakter. Publikácia sa venuje základným skupinám ochorení – intersticiálne ochorenia pľúc, alergické ochorenia a nádorové ochorenia.  Jednotlivé kapitoly podrobne približujú etiopatogenézu ochorení, klinický obraz, diagnostické metódy a diferenciálnu diagnostiku. Záverečná kapitola upriamuje pozornosť na vyšetrovacie metódy v pracovnom lekárstve. V jej prvej časti sú rozpracované funkčné vyšetrovacie metódy dýchacieho systému. Druhá časť sa venuje zobrazovacím vyšetrovacím metódam s názornou obrazovou dokumentáciou najčastejšie hlásených pneumokonióz.

E-book

Lucia Bosáková - Zuzana Dankulincová - Daniela Fiľakovská

Publication called Scientific communication and management of research projects serves as background and teaching material. Its aim is to help university students and researchers develop competencies important for scientific work, such as scientific integrity, critical work with literary sources, management of research projects and scientific communication. Publication is divided into four parts.

The first part is focused on the preparation of a research project, where it is important to know the basic ethical principles applied in the research project, but also to be able to critically assess literary sources and process them. In the second part, it provides information on the preparation of research projects and their management, including their financing, from preparation and planning, through initialization to implementation, management, logistics, monitoring, evaluation and termination. The third part pays attention to the preparation, processing and presentation of scientific results in the form of a scientific article, presentation, poster or press release, thus covering not only a professional but also a lay audience.

The final fourth part provides information about communication with a scientific journal, whether it is the process of sending, revising an article up to its publication, or the process of assessing scientific work by scientific journal editors in the process of screening and peer review.

Download the e-book for free (pdf)

 Eva Ďurovcová - Mária Mareková 

The presented textbook is intended for students of general medicine and should support their knowledge about indication and interpretation of basic biochemical tests. Clinical biochemistry continues to be one of the most rapidly advancing areas of laboratory medicine, which in line with using of modern technology more and more emphasizes the evidence-based medicine in order to improve diagnosis and monitoring of patients. Selected topics have an ambition to outline and explain the most common issues of biochemical diagnosis of in internal medicine. Individual chapters are devoted to disorders of water, electrolyte and acid-base balance, kidney and liver disease, diabetes mellitus, and biomarkers used in the diagnosis of cardiac necrosis and heart failure. Given the limited range, the textbook merely summarizes the basic knowledge that students have obtained during the study of other subjects, such as medical biochemistry, pathophysiology and internal medicine, and emphasis is given to laboratory diagnosis in accordance with the newer guidelines of professional societies. We hope that the textbook will be helpful in the study of clinical subjects and encourage students' interest in laboratory medicine.

Authors