Vybrané kapitoly z gerontológie a geriatrie. I.diel: Geriatrické syndrómy

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Zuzana Mačeková - Zuzana Katreniaková a kol.

Demencia je jednou z naliehavých a mimoriadne zložitých globálnych výziev pre zdravotnícke a sociálne systémy 21. storočia. Na Slovensku sa počet osôb s demenciou odhaduje na 62 495 (2018), pričom sa predpokladá, že v roku 2040 tento počet vzrastie na 180 000. Demencie zatiaľ patria k nevyliečiteľným chronickým stavom, ktorým nie je možné úplne predchádzať. V roku 2024 (Livingston a kol.) bol publikovaný aktualizovaný model tzv. potenciálne ovplyvniteľných faktorov, ktoré môžu prispieť k zvýšenému riziku demencie. Patria k nim: nízka úroveň vzdelania, strata sluchu, vysoký LDL cholesterol, depresia, úrazové poranenie mozgu, fyzická nečinnosť, diabetes mellitus, fajčenie, vysoký krvný tlak, obezita, nadmerná konzumácia alkoholu, sociálna izolácia, znečistené ovzdušie (vrátane pasívneho fajčenia) a strata zraku. Týchto 14 rizikových faktorov predstavuje približne 45 % celosvetových demencií, ktorým by sa teoreticky dalo predísť. Napriek narastajúcej dostupnosti informácií, úroveň povedomia verejnosti o preventívnych prístupoch v správaní sa k sebe samým, ktoré môžu nástup demencie významne oddialiť, zostáva nízka. Farmaceuti na Slovensku majú v súčasnosti adekvátne kompetencie, aby vedeli pomôcť aj v oblasti prevencie demencií. Niekedy stačí poradenstvo priamo v lekárni, vo vážnejších prípadoch odporúčanie navštíviť lekára pre ďalšie posúdenie zdravotného stavu. Každopádne, človek takto nezostáva so svojim problémom sám a dostane včasnú a potrebnú zdravotnú starostlivosť.

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Marek Stupák et al.

A well-known proverb says: "It is better to see once than to hear a hundred times." With this in mind, the electronic version of the teaching materials has been designed, as we are convinced that practical laboratory experience is irreplaceable and still holds its significance in university studies.

In the provided teaching texts, you will find a set of experiments that complement and help better understand the theoretical knowledge gained through self-study as well as lectures in an appropriate manner. Additionally, this e-version allows students, after printing and subsequently completing individual tables, observations, and conclusions, to submit them as a laboratory report that confirms they have successfully mastered the assigned tasks.

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 Soňa Grešováa kol.

The object of the practical textbook is both theory and practice. The student is familiar with the investigative methods used in patients at different clinics as well as research institutes. Investigative methods are a source of knowledge about the state of the internal environment of an individual, the functionality of the various systems of the body, based on which it is possible to establish a conclusion on whether the individual is healthy or not. 

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Zuzana Dankulincová, Daniela Husárová

In the context of the deteriorating state of adolescent mental health, it is extremely important to optimize the existing mental health care system in Slovakia. There is still little comprehensive and coherent information about the functioning of the system and the process of providing assistance within professional care, its shortcomings or suggestions for improvement. This is not possible without a deep knowledge of the perspective and experiences of adolescents with mental problems themselves. The aim of this publication is therefore to present adolescents' views on the professional assistance provided as a result of experienced mental problems within the existing care system in Slovakia.

The findings from a qualitative study that focused on the views of young people themselves are presented. The chapters of the monograph capture their views on the perception of mental health problems in society, their experiences with identifying emerging problems and seeking professional help, and their experiences with the care process itself and its forms. They also capture their overall experience with both care and care providers, as well as with leaving care and its impacts in various areas. Finally, a view is presented of possible recommendations that could improve the mental health care provided from the adolescents' perspective.

This publication is intended primarily for all professionals working with adolescents with mental health problems in all branches of care, teachers and other educational staff who are in contact with them every day at school, and last but not least, all competent policy makers who care about the mental health of adolescents and have the power to improve the care provided to them.

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Mária Rašiová

Cardiovascular diseases are among the main causes of morbidity and mortality in developed countries. Academic textbook: Selected Chapters from Angiology is devoted to the most common vascular diseases that the angiologist encounters on a daily basis.

Dilated artery diseases (abdominal aortic aneurysm), as well as stenotizing diseases of peripheral arteries, are described. Diseases such as deep vein thrombosis, thrombophlebitis and chronic venous insufficiency are discussed in the venous vascular system section. I also deal with the most common lymphatic vascular system disease ˗ lymphoedema.

In the individual chapters the risk factors of the diseases, symptoms and signs, diagnostics, treatment modalities (pharmacological therapy, endovascular therapy, angiosurgical therapy) and possible complications of the therapy are briefly analyzed.

My priority was to present the information in a logical, interesting and comprehensible form for students and for common clinical practice.

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Tatiana Kimáková - Vladimír Pavlík

The scientific monograph focuses on the characteristics of free radicals, reactive oxygen and nitrogen species, oxidative stress, and its impact on various diseases. A significant portion is dedicated to antioxidants, their classification based on multiple criteria, the characteristics of selected antioxidants in terms of their functions, manifestations of their deficiency and excess, and the overall antioxidant capacity of the body.

A special section is devoted to enzyme-based antioxidants, natural sources of antioxidants in the form of vitamins, trace elements, flavonoids, polyphenols, and coenzyme Q10. To provide a clearer understanding of antioxidants and their influence on population health, the monograph presents results from a research project included in the program "Research Support for Enhancing the Defense Capabilities of the Czech Republic in NATO Structures."

The research was conducted between 2010 and 2012 as part of preventive rehabilitation programs for professional soldiers with a sports component. The study involved 218 professional soldiers, including 180 men and 38 women, with an average age of 33.3 years. The current health status and dietary habits of the soldiers were assessed using questionnaires.

The study described the saturation of the observed group with antioxidant vitamins and statistically evaluated the relationship between their levels and the risk indicators for the development of cardiovascular diseases. Individual analyses were performed using the Reflotron device calibrated with Reflotron Precinorm control serum. Following blood collection, all participants underwent anthropometric examinations (body weight, height, waist circumference), blood pressure measurements, heart rate monitoring, and physical fitness assessments through simple functional tests.

This scientific monograph is suitable for the scientific community, students of medical, veterinary, and natural sciences, as well as public health students at all levels of university education. It is also intended for informed members of the public.

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Tatiana Kimáková

This scientific monograph is a comprehensive scientific work focused on the presence and effects of mercury in the environment, as well as the health risk factors associated with it.

The monograph presents a characterization of mercury in a multidisciplinary scope, discusses its use in industry and healthcare, and describes the negative impacts of mercury on the environment and public health. It also provides proposals and recommendations for at-risk groups. The monograph includes a comprehensive study of mercury concentration in samples of domestic and foreign production commodities and plant samples using the atomic absorption spectrometer AMA 254.

This scientific monograph is suitable for the scientific community, students of medical, veterinary, natural sciences, and agricultural fields, as well as public health students at all three levels of university study. It is also intended for all interested members of the informed public.

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Helena Mičková -  Jozef Židzik -  Mária Mareková - Marek Stupák - 

Peter Urban

Modelové otázky na prijímacie skúšky pre bakalárske štúdium sú určené záujemcom o bakalárske študijné programy na Univerzite Pavla Jozefa Šafárika v Košiciach, Lekárskej fakulte. Publikácia obsahuje 500 otázok z biológie a 500 otázok z chémie, ktoré tvoria podklady písomných testov na prijímacie skúšky. Otázky na prijímacích skúškach však nemusia presne kopírovať modelové otázky. Testy z chémie a biológie pokrývajú tie okruhy učiva z predmetov biológia a chémia na slovenských gymnáziách, vedomosti z ktorých sú vyžadované od poslucháčov bakalárskych študijných smerov (napr. ošetrovateľstvo, fyzioterapia, verejné zdravotníctvo). Otázky z biológie a z chémie sú predkladané v dvoch samostatných celkoch. Odpovede na otázky sú riešené formou ponúkaných variantných odpovedí, obsahujúcich správne aj nesprávne možnosti. Správne odpovede sú vyznačené v kľúči na konci publikácie.

Príklady z chémie tvoria zvláštnu časť, v ktorej nie sú ponúkané variantné odpovede. Pre lepšiu kontrolu správnosti výpočtu je v zátvorke uvedený jeden správny výsledok (z viacerých možných – líšiacich sa napr. v jednotkách – gramy, miligramy, móly). Autori publikácie sa snažili minimalizovať možné chyby v texte a vyhnúť sa nejednoznačným formuláciám otázok a odpovedí. Modelové otázky sú okrem prípravy na prijímacie skúšky na UPJŠ LF v Košiciach vhodné aj na zopakovanie gymnaziálneho učiva z biológie a chémie pred maturitnou skúškou.

 Kvetoslava Rimárová 

The theme of the presented university textbook is a summary of selected basic knowledge of hygiene - environmental medicine. The script includes significant areas of environmental medicine as a science: the basics of environmental medicine, health and prevention issues of environmental health and risk assessment of potential exposure, the issue of air pollution, indoor pollution, problems of drinking water, the action of soil and solid waste, further issue of housing, nutrition and the impact of working conditions on health. Nutritional factors textbooks dealing with issues of rational nutrition, describe the individual components of nutrition, but also address the issue of food hygiene and the possibilities of foodborne infections. One chapter is also devoted to the impact of environmental conditions on health of children and youth. 

University textbook as a manuscript consists from 199 manuscript pages, is divided into 12 basic chapters, contains 36 citations in the literature.  In the Preface, the issue of categorization of diseases and define the basic concepts of health, prevention. Other chapters deal with the above selected chapters hygiene.

This university textbook comes as a basic university textbook for students of general  medicine in the English language, for students of bachelor's and master's studies  of medical schools - mainly bachelor's and master' program of  "Public health". Students of medicine and dentistry can also use these textbooks as an educational tool in the study of other subjects in the teaching of public health.

Autor

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Jana Mašlanková

Colorectal carcinoma is the most common malignant tumor of the digestive system, and its rising incidence in Slovakia—particularly among the male population—is alarming. Although significant progress has been made in the diagnosis, screening, and treatment of patients with advanced colorectal cancer, therapeutic options remain limited, necessitating the discovery of additional markers to serve as prognostic predictors.

This monograph aims to draw the attention of the professional community to the critical role and significance of the TGF-β signaling pathway in the initiation, progression, and treatment of colorectal carcinoma. A substantial portion of the text focuses on lesser-known emerging trends and ongoing clinical trials for colorectal cancer patients.

The monograph aspires to provide a balanced resource that serves as an engaging informational tool not only for specialist physicians but also for medical faculty students. By integrating novel insights and clinical data, it seeks to bridge gaps in current understanding and highlight potential avenues for future research and therapy.

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Jozef Židzik - Terézia Hudáková - Martina Šemeláková - Ján Šalagovič

Methods in human genetics and molecular biology encompass various experimental, diagnostic and analytical techniques used to investigate the structure, function, expression, and regulation of genes, as well as general molecular processes in human cells. The university textbook Methods in Human Genetics and Molecular Biology provides a comprehensive overview of classical and modern experimental and analytical procedures. In fifteen chapters, it addresses methods such as PCR, RFLP, FISH, Western blot, DNA sequencing, DNA microarrays, molecular cloning, cytogenetic analysis, and forensic genetic analysis. The book is primarily intended as study material for the course of the same name taught in the 2nd year of study at the UPJŠ Faculty of Medicine, but it can also be used by all university students in the fields of biology, biotechnology, and related disciplines.

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E-publication

Miriam Kozárová

Simulation-based medical education has become an integral part of medical education in the 21st century. It represents a modern and effective way to enable medical, nursing, emergency medicine, and other healthcare team members to safely develop clinical skills, decision-making abilities, and teamwork. Simulation-based medical education (SBME) is primarily about opportunities to try out and experience medical/nursing/rescue procedures in a safe environment without any risk to real patients.

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Lucia Bosáková - Zuzana Dankulincová - Daniela Fiľakovská

Publication called Scientific communication and management of research projects serves as background and teaching material. Its aim is to help university students and researchers develop competencies important for scientific work, such as scientific integrity, critical work with literary sources, management of research projects and scientific communication. Publication is divided into four parts.

The first part is focused on the preparation of a research project, where it is important to know the basic ethical principles applied in the research project, but also to be able to critically assess literary sources and process them. In the second part, it provides information on the preparation of research projects and their management, including their financing, from preparation and planning, through initialization to implementation, management, logistics, monitoring, evaluation and termination. The third part pays attention to the preparation, processing and presentation of scientific results in the form of a scientific article, presentation, poster or press release, thus covering not only a professional but also a lay audience.

The final fourth part provides information about communication with a scientific journal, whether it is the process of sending, revising an article up to its publication, or the process of assessing scientific work by scientific journal editors in the process of screening and peer review.

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Tatiana Muchová

Medicína stále napreduje, je stále vo vývoji. Rádiologické zobrazovacie metódy prežívajú stále výrazný rozvoj vďaka prístrojovej technike, ktorá umožňuje zavádzať nové diagnostické metódy, ako sú USG vyšetrenia s kontrastnou látkou, špeciálne CT vyšetrenia, ku ktorým je potrebný viacradový CT prístroj – CT angiografia, CT enteroklýza, CT irigografia, CT virtuálna kolonoskopia. Magnetická rezonancia už v dnešnej dobe nie je nedostupné vyšetrenie, predstavuje výrazný pokrok v diagnostike.

Vďaka moderným prístrojom môžeme vykonávať rôzne intervenčné diagnostické aj terapeutické výkony, ako sú biopsie, drenáže...

Tieto učebné texty sú určené študentom lekárskych fakúlt, obsahuje základné poznatky z rádiológie.

Publikácia je rozdelená na všeobecnú a špeciálnu časť s následným delením podľa jednotlivých modalít a vyšetrovaných orgánov.

Rádiológia predstavuje prácu s obrazovou dokumentáciou, preto aj táto publikácia je obohatená veľkým počtom obrázkov z jednotlivých rádiologických vyšetrovacích modalít.

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Miriam Kozárová

The publication "News in Diabetology and Lipidology" focuses on extremely relevant topics in diabetology and lipidology, reflecting the state of these issues in light of the recommendations from professional societies from 2019. In diabetology, it primarily addresses the intensification of antidiabetic treatment using modern drug classes—specifically, incretin enhancers and sodium-glucose cotransporter-2 (SGLT-2) inhibitors (gliflozins). Few medical fields have experienced such a development of new pharmacological options as diabetology has in the last two decades. While pharmacotherapy for type 2 diabetes (DM2) was limited to the use of biguanides, sulfonylurea derivatives, and insulin throughout the second half of the last century, recent years have introduced entirely new groups of oral antidiabetics with cardio- and nephroprotective effects. In lipidology, it pertains to the new recommendations from the European Atherosclerosis Society (EAS) with new treatment goals for serum lipids and lipoproteins, including the use of biological therapies.

This textbook is primarily intended for medical students in doctoral studies and doctoral candidates, as well as for physicians preparing for specialization exams in internal medicine, endocrinology, diabetology, metabolic disorders and nutrition, as well as cardiology and angiology. I believe that readers will find information in this publication that will aid them in their studies and translate into their daily clinical practice.

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