Novinky v diabetológii a lipidológii

Vladimíra Tomečková

Nature, as well as the human body, contains an abundant quantity of organic molecules. This textbook describes selected oxygen, sulfur, nitrogen derivatives of hydrocarbons, heterocyclic compounds of their reactions, which are important in the human body or are found in pharmaceutical active substances, poisons, foodstuffs and heat-treated food. The last part of the textbook describes the isomerism of organic compounds, which enables dynamic changes in the structure of molecules that have different properties. Nature is filled with different plants and animals and is the first laboratory to produce bioactive organic natural compounds. These compounds are compatible with human cells and are applicable as therapeutic medicine. There is an effort to reproduce natural molecules in chemical laboratories, but they cannot be as perfect as the natural ones. Synthetic molecules can serve as a model for multiple studies, but there still does not exist a magic panacea pill or a perfect copy of nature, for the treatment of various diseases. Knowledge about the regenerative and toxic effect of medicinal substances in dependence on their structure (type and number of substituents) is very important for the understanding of their role in modulation of health and disease in dependence on their concentration. Compounds can be used daily only in recommended doses (higher doses can be toxic), but still will not replace a healthy diet. People need a varied diet to be healthy, in which are all necessary nutrients, what Hippocrates demonstrated long ago “Let food be the medicine, and let medicine be the food.” This book is written for students who select bioorganic chemistry subject during the study of general medicine or dentistry as well as for motivated students who would like to practice their knowledge and wish to improve in this subject and for students who would like to learn simplified basic organic reactions with their future application in biochemistry. Learn the simple models mainly through creative simple instruction by using different colours, by repetition, practice by drawing of formulas by hand (at least three times) and memorization of common names of compounds and their reactions which have application in biochemistry. Thus, establishing simple educational methods how to distinguish organic molecules according to the colours of a functional group can promote universal learning for all students who thought that chemistry is a difficult subject, but hopefully they change their opinion after study of this book.

Keywords: organic molecules, oxygen, sulfur, nitrogen derivatives of hydrocarbons, heterocyclic compounds, chemical reactions, isomerism of organic compounds

H.Mičková - V.Habalová - J.Židzik - E.Slabá

E-book

Kvetoslava Rimárová

This manual is published as an auxiliary methodological script for students of bachelor and master courses of medical faculties - especially bachelor and master courses of ‘Public Health’.

Students of general medicine and dentistry can also use these teaching texts as an educational aid when studying the subject “Hygiene”, which is taught either on its own or as part of broader subjects, e.g. “Public Health”. 

Download the e-book for free (pdf)

 Kvetoslava Rimárová 

The theme of the presented university textbook is a summary of selected basic knowledge of hygiene - environmental medicine. The script includes significant areas of environmental medicine as a science: the basics of environmental medicine, health and prevention issues of environmental health and risk assessment of potential exposure, the issue of air pollution, indoor pollution, problems of drinking water, the action of soil and solid waste, further issue of housing, nutrition and the impact of working conditions on health. Nutritional factors textbooks dealing with issues of rational nutrition, describe the individual components of nutrition, but also address the issue of food hygiene and the possibilities of foodborne infections. One chapter is also devoted to the impact of environmental conditions on health of children and youth. 

University textbook as a manuscript consists from 199 manuscript pages, is divided into 12 basic chapters, contains 36 citations in the literature.  In the Preface, the issue of categorization of diseases and define the basic concepts of health, prevention. Other chapters deal with the above selected chapters hygiene.

This university textbook comes as a basic university textbook for students of general  medicine in the English language, for students of bachelor's and master's studies  of medical schools - mainly bachelor's and master' program of  "Public health". Students of medicine and dentistry can also use these textbooks as an educational tool in the study of other subjects in the teaching of public health.

Autor

E-book

Adriana Boleková (ed.)

Proceedings of Scientific Works

The Košice Morphological Day is an annual May meeting of morphologists, primarily attended by Košice morphological workplaces. On this occasion, a collection of scientific works is regularly published.

This year's collection was published on the occasion of the 23rd Košice Morphological Day, which did not take place due to the poor epidemiological situation.

In the collection, the authors present the results of their scientific-research and pedagogical activities, which are in the form of theoretical overview studies and research works.

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Tomáš Toporcer - Adrián Kolesár

The textbook "Heart surgery for medics" was created in response to repeated requests from students of the Faculty of Medicine P.J.Šafárik University, for the surgery state exam study material. In terms of content, the text corresponds to the required knowledges in cardiac surgery, needed to pass the state exam in surgery. Orientation in the issue of cardiac surgery is not only necessary for students whose specialization will be closely related to the given field. Basic knowledge of cardiac surgery is necessary for every medical faculty graduate. Knowing the treatment options, but also the possible complications of individual cardiac surgical procedures, is necessary for most medical specialties. Only by mastering the basics of each medical field can the patient be properly, adequately and modernly managed.

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Mária Mareková - Marek Stupák - Peter Urban - Jana  Mašlanková -

Beáta Hupková - Miroslava Rabajdová

Publikácia je určená záujemcom o štúdium na UPJŠ v Košiciach, Lekárskej fakulte v odbore všeobecné lekárstvo a zubné lekárstvo. Obsahuje 1500 modelových otázok z chémie, ktoré sú spracované v súlade so vzdelávacím programom na gymnáziách a ktoré tvoria podklady písomných testov na prijímacích skúškach. Otázky na prijímacích skúškach však nemusia presne kopírovať otázky v tejto publikácii. Odpovede na otázky sú riešené formou ponúkaných variantných odpovedí obsahujúcich správne aj nesprávne možností, pričom správne odpovede sú uvedené v kľúči na konci publikácie. Táto publikácia vám poskytne možnosť overiť si hĺbku a rozsah vašich vedomostí z chémie, ktoré ste nadobudli počas stredoškolského štúdia a zároveň vám uľahčí prípravu na úspešné absolvovanie prijímacej skúšky. Autori problematiku rozdelili do kapitol, čo vám umožní rýchlo sa zorientovať a zistiť, ktorej oblasti sa musíte v štúdiu viac venovať. Cieľom predkladanej publikácie je umožniť každému uchádzačovi, ktorý má o štúdium na lekárskej fakulte vážny záujem, dobre sa pripraviť na prijímacie konanie a v prípade prijatia, mať dobrý základ na štúdium daného odboru.

Gabriel Koľvek

Tento učebný text je zameraný na najčastejšie ochorenia obličiek detského veku. Venuje sa vybraným vrodeným (ako napr. vrodené anomálie obličiek a močových ciest) ako aj získaným ochoreniam obličiek (infekcie močových ciest, nefrotický syndróm, hemolyticko-uremický syndróm a ďalšie), ktoré sú opísané komplexne od epidemiológie, patofyziológie, cez klinický obraz, diagnostiku až po liečbu a prognózu. Texty zahŕňajú najnovšie diagnostické a terapeutické postupy opierajúce sa o recetné vedecké poznatky. Informácie uvedené v texte môžu významne pomôcť k úspešnému absolvovaniu štátnej skúšky z predmetu Pediatria. Text je starostlivo vybraný a rozsah kondenzovaný tak, aby vyhovoval predovšetkým potrebám pregraduálneho štúdia a zároveň dopĺňal vedomosti a skúsenosti získané na prednáškach a praktických cvičeniach. Učebnica tiež poskytuje základné informácie pre lekárov v špecializačnej príprave.

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Pavol Jarčuška - Pavol Kristian - Ivan Schréter (eds.)

The abstract almanac was issued at the occasion of XXII. Slovak – Czech congress on infectoius diseases held in Jasná.

Overall it contains 70 reports that cover current issues in infectology. Contributions are focused on patients with infections caused by multidrug resistant organisms, HIV infected patients, patients with hepatitis and infections in immunocompromised patients.

Thers is a special section dedicated to new aspects in nursing care.

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Jozef Kafka

Behavior, in the slovak language expressed as an intention, belongs to basic mental processes of every individual. In this work I consider it as the basic component of an individual having two sides, outer- and inner side. I present it in the scheme No. 2.

The problem of behavior can not be fully covered, although there is a lot of writing, discussing and experimenting by ancient time.

The work may offer only few comments, approaching maily disorders of behavior. I present the original explanation of these disorders, dividing them on primary and derived ones. Primary disorders create the core of the disorder, derived disorders create a component of other disorders.

My classification of primary disorders is as follows:

1. age dependent disorders of behavior
2. disorders in the dynamical structure and in phases of behavior
3. integrative disorders of behavior, disorders of the will, which is the sign of the developed behavior of the individual.

The work is addresses to everone who is interested in his/her owm behavior, but especially for the Medical faculty and psychiatrists, for students of all our faculties.

Author 

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Nikita Bobrov a kol.

Pojem lekárska etika je interpretovaný ako aplikovaná a zároveň aj profesijná etika. Ako bioetická disciplína pozostáva z troch normatívnych častí, a to biogenézy, bioterapie a tanatológie. Z etického aspektu je medicína súčasťou klinickej bioetiky, avšak v súčasnej etape ešte chýba „etika založená na dôkazoch“ (evidence-based ethics). V podmienkach štandardizácie zdravotnej starostlivosti dochádza k nadmernému rozvoju niektorých súčastí bioetiky (ako napr. etické kódexy, koncepcia autonómie pacienta), ale aj k redukcii najmä jej klinickej zložky (ako komunikácia, tanatológia, eutanázia, dystanázia, márna liečba). Súčasným legislatívnym úsilím dochádza k redukcii práv zdravotníckych pracovníkov, predovšetkým v korporatívnej autonómii. Základnou úlohou lekárskej etiky je výchova medicínskeho profesionalizmu, ktorý je definovaný ako profesijné zosúladenie odborného, etického a právneho uvažovania a ako východiskový stav pre rozmýšľanie v hodnotových reláciách, s reflektovaním bioetického priestoru v klinickej a odbornej praxi. Keďže spoločnosť deklaruje zdravie ako svoju prioritu, tak by táto priorita mala pozitívne ovplyvňovať celý systém zdravotnej starostlivosti a jej základnou ideou by mal byť systém zdravotníctva založený na humanistickej etickej paradigme so spoločenskou a profesijnou aplikáciou. Morfologické a predklinické disciplíny v prvých ročníkoch výučby študentov majú veľký význam, nakoľko formujú u študentov úctu k ľudskej podstate cez etický vzťah k anatomickým preparátom a k biologickému materiálu pochádzajúcemu z mŕtveho ľudského tela. Na viacerých morfologických ústavoch a katedrách vidíme tradičné mottá „Hic locus est, ubi mors gaudet succurere vitae“ (Tu smrť slúži pre víťazstvo života) alebo „Mortui vivos docent“ (Mŕtvi učia živých), ktoré reflektujú hlboký humanistický zmysel štúdia anatómie, patológie a iných disciplín na telách zomrelých ľudí s uplatnením základných princípov bioetiky, ako je celistvosť osoby a osobnosti, váženie si ľudských hodnôt a autonómie. Každý človek je jedinečný a neopakovateľný nielen z hľadiska odlišnej farby pleti, vlasov, očí, stavby tela, ale ja z pohľadu vnímania, zmýšľania a temperamentu. V určitom momente existencie človeka však prichádza životný útlm, choroba alebo úraz, stav, kedy sa všetko úplne zastaví a už nikdy sa nevráti späť. Stane sa tak či už prirodzenou alebo násilnou smrťou. Otázky týkajúce sa problematiky umierania, smrti a posmrtných zmien a ich etické a právne aspekty sa práve analyzujú a zodpovedajú v rámci štúdia tanatológie a humánnej tafonómie.

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Tatiana Kimáková - Štefan Tóth - Ivan Uher

The scientific monograph is devoted to active and healthy aging, its basic indicators, involutional changes, or the relationship between healthy aging and lifestyle. Adopting a healthy lifestyle and actively participating in health care for yourself are important elements in all stages of our lives, and therefore in healthy aging. We describe the possibilities of older people to slow down the adverse changes associated with aging through education and educational activities of various types.

The scientific monograph also includes our own research focused on overall health and selected lifestyle risk factors, especially consumption of various food groups, smoking, alcohol, physical activity and stress of participants at the University of the Third Age at Pavol Jozef Šafárik University in Košice, Slovak and foreign university students at the Medical Faculty of the Pavol Jozef Šafárik University in Košice. The scientific monograph is appropriate for the scientific community, students of medical and natural sciences, public health for all three degrees of university study.

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Martina Zavacká a kolektív

Kniha „DIABETICKÁ NOHA Z POHĽADU CIEVNEHO CHIRURGA“ obsahuje 14 kapitol. Pojednáva o syndróme diabetickej nohy z multidisciplinárneho pohľadu viacerých odborníkov: angiochirurga, diabetológa, chirurga, podiatra, röntgenológa, neurológa a algeziológa. Úvodné kapitoly majú charakter propedeutiky, čo má taktiež význam aj pre pregraduálnu výchovu. Nasledujúce kapitoly sa zaoberajú vznikom syndrómu, výskytom, jeho diagnostikou, terapeutickými postupmi, pridruženými postihnutiami neurologického charakteru, starostlivosťou podiatra a algeziológa pri pretrvávaní bolestí. Ďalšie časti sú vyhradené chirurgickej a endovaskulárnej liečbe tepien cestou cievneho chirurga a intervenčných angiológov. Nezabúdajúc na problematiku amputácií a správnu rehabilitáciu pacientov s diabetom.  V knihe nájdu poučenie cievni chirurgovia, angiológovia, všeobecní chirurgovia, diabetológovia, neurológia, röntgenológovia, podiatri  a všeobecní lekári.

Kniha je zdrojom najnovších teoretických i praktických informácií pre postgraduálnu výchovu vyššie spomenutých odborníkov.

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Ján Varga

The cancer is the second most common reason of the death in human population. lt is responsible for approximately 10 million of death every year. Oncogynecology represents · one of the most pr ogressive part of gynecology. The interest is focused on vulvar cancer, vaginal cancer, cervical cancer, uterine cancer, fallopian tube carcinoma, ovarian cancer as well as breast cancer. Due to the range of the issue there are own workplaces ta king care just for the patients with oncogyneco logical diseases. The knowledge from oncogynecology are inevitably needed to pass the state exam as well as specialization from Gynecology and obstetrics. The presented publication is focused to mentioned oncogynecological diseases.

The anatomy and histology of the vulva, vagína, cervix, uterus, fallop ian tube and ovary are described in detail. Every described carcinoma contains part about etiopathogenesis, clinical presentation, diagnostic, classification and therapy. The paper contains information suitable for students of medical faculties as well as young doctors before specialization.

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Mária Rašiová

Cardiovascular diseases are among the main causes of morbidity and mortality in developed countries. Academic textbook: Selected Chapters from Angiology is devoted to the most common vascular diseases that the angiologist encounters on a daily basis.

Dilated artery diseases (abdominal aortic aneurysm), as well as stenotizing diseases of peripheral arteries, are described. Diseases such as deep vein thrombosis, thrombophlebitis and chronic venous insufficiency are discussed in the venous vascular system section. I also deal with the most common lymphatic vascular system disease ˗ lymphoedema.

In the individual chapters the risk factors of the diseases, symptoms and signs, diagnostics, treatment modalities (pharmacological therapy, endovascular therapy, angiosurgical therapy) and possible complications of the therapy are briefly analyzed.

My priority was to present the information in a logical, interesting and comprehensible form for students and for common clinical practice.

Author

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Iveta Cimboláková a kol.

Premisa „dnešný výskum tvorí zdravotnú starostlivosť zajtrajška“ vyjadruje význam medicínskeho výskumu a dôvod jeho vykonávania. Vedecký výskum a pokroky v biomedicínskych vedách a ich aplikácia v lekárskej praxi a v procese poskytovania zdravotnej starostlivosti, však prinášajú nové problémy v oblasti etiky. Samotný biomedicínsky výskum si vyžaduje presné definovanie hypotéz, ktoré sú overované jednak v laboratórnych podmienkach ako aj na pokusných zvieratách. Aj keď klinické štúdie na ľudských subjektoch predpokladajú prospech jednotlivým účastníkom a rozvíjajú základné biomedicínske poznatky, predsa však znamenajú aj určité riziká v závislosti od charakteru výskumu. Tieto riziká musia byť minimalizované, pričom experiment sa má vykonávať slobodne a zároveň musí prebiehať v rámci špecifických opatrení na ochranu všetkých zúčastnených, a to nielen pokusných osôb, ale aj samotných výskumníkov. Je zrejmé, že každý výskum s účasťou ľudí je nevyhnutné realizovať v súlade so všeobecne prijatými etickými princípmi ako sú prospešnosť, autonómia, spravodlivosť a neškodnosť. V biomedicínskom výskume sa princíp autonómie uplatňuje osobitne v procese slobodného informovaného súhlasu, ktorý môže účastník, či už terapeutického alebo bádateľského experimentu, kedykoľvek odvolať. Je nutné uviesť, že pokroky v medicíne sú takmer vždy spojené s výskumom na zvieratách, čo si taktiež vyžaduje zabezpečenie špecifických etických noriem a prístupov. Z etického pohľadu sú zvlášť kritizované pokusy na zvieratách vykonávané pre potreby kozmetických firiem. Významnú úlohu pri posudzovaní etických aspektov a kontrole výskumných projektov či už na zvieratách alebo na človeku, zohrávajú nezávislé etické komisie. Predložená publikácia poskytuje prehľad všeobecných podmienok a etických zásad výskumu zahrňujúceho laboratórne zvieratá a ľudské subjekty, problematiku odborného a etického posudzovania projektov ako aj podvodu a publikovania výsledkov. V súčasnosti sme svedkami nesmierneho pokroku v molekulárne-biologických vedách, čo prináša etické dilemy aj v oblasti genetiky. Z uvedeného dôvodu je jedna z kapitol venovaná najnovším poznatkom v tejto oblasti.

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Vladimíra Tomečková

Nature, as well as the human body, contains an abundant quantity of organic molecules. This textbook describes selected oxygen, sulfur, nitrogen derivatives of hydrocarbons, heterocyclic compounds of their reactions, which are important in the human body or are found in pharmaceutical active substances, poisons, foodstuffs and heat-treated food. The last part of the textbook describes the isomerism of organic compounds, which enables dynamic changes in the structure of molecules that have different properties. Nature is filled with different plants and animals and is the first laboratory to produce bioactive organic natural compounds. These compounds are compatible with human cells and are applicable as therapeutic medicine. There is an effort to reproduce natural molecules in chemical laboratories, but they cannot be as perfect as the natural ones. Synthetic molecules can serve as a model for multiple studies, but there still does not exist a magic panacea pill or a perfect copy of nature, for the treatment of various diseases. Knowledge about the regenerative and toxic effect of medicinal substances in dependence on their structure (type and number of substituents) is very important for the understanding of their role in modulation of health and disease in dependence on their concentration. Compounds can be used daily only in recommended doses (higher doses can be toxic), but still will not replace a healthy diet. People need a varied diet to be healthy, in which are all necessary nutrients, what Hippocrates demonstrated long ago “Let food be the medicine, and let medicine be the food.” This book is written for students who select bioorganic chemistry subject during the study of general medicine or dentistry as well as for motivated students who would like to practice their knowledge and wish to improve in this subject and for students who would like to learn simplified basic organic reactions with their future application in biochemistry. Learn the simple models mainly through creative simple instruction by using different colours, by repetition, practice by drawing of formulas by hand (at least three times) and memorization of common names of compounds and their reactions which have application in biochemistry. Thus, establishing simple educational methods how to distinguish organic molecules according to the colours of a functional group can promote universal learning for all students who thought that chemistry is a difficult subject, but hopefully they change their opinion after study of this book.

Keywords: organic molecules, oxygen, sulfur, nitrogen derivatives of hydrocarbons, heterocyclic compounds, chemical reactions, isomerism of organic compounds

H.Mičková - V.Habalová - J.Židzik - E.Slabá

E-book

Kvetoslava Rimárová

This manual is published as an auxiliary methodological script for students of bachelor and master courses of medical faculties - especially bachelor and master courses of ‘Public Health’.

Students of general medicine and dentistry can also use these teaching texts as an educational aid when studying the subject “Hygiene”, which is taught either on its own or as part of broader subjects, e.g. “Public Health”. 

Download the e-book for free (pdf)

 Kvetoslava Rimárová 

The theme of the presented university textbook is a summary of selected basic knowledge of hygiene - environmental medicine. The script includes significant areas of environmental medicine as a science: the basics of environmental medicine, health and prevention issues of environmental health and risk assessment of potential exposure, the issue of air pollution, indoor pollution, problems of drinking water, the action of soil and solid waste, further issue of housing, nutrition and the impact of working conditions on health. Nutritional factors textbooks dealing with issues of rational nutrition, describe the individual components of nutrition, but also address the issue of food hygiene and the possibilities of foodborne infections. One chapter is also devoted to the impact of environmental conditions on health of children and youth. 

University textbook as a manuscript consists from 199 manuscript pages, is divided into 12 basic chapters, contains 36 citations in the literature.  In the Preface, the issue of categorization of diseases and define the basic concepts of health, prevention. Other chapters deal with the above selected chapters hygiene.

This university textbook comes as a basic university textbook for students of general  medicine in the English language, for students of bachelor's and master's studies  of medical schools - mainly bachelor's and master' program of  "Public health". Students of medicine and dentistry can also use these textbooks as an educational tool in the study of other subjects in the teaching of public health.

Autor

E-book

Adriana Boleková (ed.)

Proceedings of Scientific Works

The Košice Morphological Day is an annual May meeting of morphologists, primarily attended by Košice morphological workplaces. On this occasion, a collection of scientific works is regularly published.

This year's collection was published on the occasion of the 23rd Košice Morphological Day, which did not take place due to the poor epidemiological situation.

In the collection, the authors present the results of their scientific-research and pedagogical activities, which are in the form of theoretical overview studies and research works.

Download the e-book for free  (pdf)