Všeobecná patofyziológia

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Miriam Kozárová

The publication "News in Diabetology and Lipidology" focuses on extremely relevant topics in diabetology and lipidology, reflecting the state of these issues in light of the recommendations from professional societies from 2019. In diabetology, it primarily addresses the intensification of antidiabetic treatment using modern drug classes—specifically, incretin enhancers and sodium-glucose cotransporter-2 (SGLT-2) inhibitors (gliflozins). Few medical fields have experienced such a development of new pharmacological options as diabetology has in the last two decades. While pharmacotherapy for type 2 diabetes (DM2) was limited to the use of biguanides, sulfonylurea derivatives, and insulin throughout the second half of the last century, recent years have introduced entirely new groups of oral antidiabetics with cardio- and nephroprotective effects. In lipidology, it pertains to the new recommendations from the European Atherosclerosis Society (EAS) with new treatment goals for serum lipids and lipoproteins, including the use of biological therapies.

This textbook is primarily intended for medical students in doctoral studies and doctoral candidates, as well as for physicians preparing for specialization exams in internal medicine, endocrinology, diabetology, metabolic disorders and nutrition, as well as cardiology and angiology. I believe that readers will find information in this publication that will aid them in their studies and translate into their daily clinical practice.

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Adriana Boleková (ed.)

Proceedings of Scientific Works

The Košice Morphological Day is an annual May meeting of morphologists, primarily attended by Košice morphological workplaces. On this occasion, a collection of scientific works is regularly published.

This year's collection was published on the occasion of the 23rd Košice Morphological Day, which did not take place due to the poor epidemiological situation.

In the collection, the authors present the results of their scientific-research and pedagogical activities, which are in the form of theoretical overview studies and research works.

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Dominik Šafčák

Both clinical and radiation oncology are the most developing parts of medicine. Regardless of the physician´s specialization, all of them will have to face subjects with cancer in their daily clinical practice. It includes not only the treatment itself, but also obtaining the diagnosis, but also differential diagnosis and treatment of different adverse events caused by oncological treatment. This publication provides basic data about tumor characteristics necessary for oncologists to determine the final stage and choose the best treatment strategy. In addition, explains the basic oncological terms, forms of therapy, and provides information about treatment timing, combination strategies and expected outcomes. It explains main endpoints of clinical trials performed in oncology to understand them.  In the second part this publication describes mechanism of action of all treatment modalities used in clinical oncology, provides information about potential side effects and basic knowledge how to deal with them. The last chapter is focused on palliative care, how to relieve symptoms of dying patient and how to deal with cancer-related pain. 

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E-publication

Zora Lazúrová

This publication is intended for medical students and offers a systematic overview of anemia from the perspective of clinical practice. The publication includes a classification of anemias based on pathophysiological mechanisms, including impaired red blood cell production, increased destruction and blood loss. It provides detailed description of iron, vitamin B12, and folic acid deficiencies, as well as aplastic and hemolytic anemias, including some of the rare hereditary forms. The text features chapters on laboratory diagnostics, investigative methods, and interpretation of results. The publication is focused on clinical presentation, differential diagnostic approach, and the basic principles of treatment for each type of anemia. The material is supplemented with images and tables to help in the understanding of this complex topic. The fundamentals of clinical management are presented in schematic differential diagnostic algorithms. The aim of this publication is to provide a clear, didactically structured, and practically oriented resource that supports the teaching of internal medicine. It is suitable not only for exam preparation, but also as an introduction to the clinical practice.

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Mária Mareková a kol.

Predkladaná vysokoškolská učebnica predstavuje základy biochémie a je určená predovšetkým pre bakalárske  študijné programy (napr. ošetrovateľstvo, fyzioterapia, verejné zdravotníctvo). Vysokoškolská učebnica predstavuje zjednodušenú alternatívu lekárskej biochémie a je svojím obsahom aj rozsahom vhodná pre študentov nelekárskych študijných odborov. Okrem priblíženia základných metabolických dejov prebiehajúcich v organizme človeka, ponúka aj stručný prehľad klinicko-biochemických parametrov štandardne vyšetrovaných pri podozrení na ich poruchy. Snaží sa poskytnúť študentom, predovšetkým zdravotníckych študijných programov, základy lekárskej a klinickej biochémie a oboznámiť ich s najčastejšie používanými metódami v biochemickom laboratóriu v primeranom rozsahu. Chce prispieť k prehĺbeniu vedomostí o metabolizme zdravého, ale i chorého človeka, resp. o klinicko-biochemických diagnostických postupoch a laboratórnych vyšetreniach a vzbudiť záujem o ďalšie vzdelávanie. Budeme radi, ak poslúži nielen ako príprava na skúšku, ale bude inšpiráciou napr. pre realizáciu diplomových prác zameraných na vedecko-výskumnú oblasť klinickej biochémie či laboratórnej medicíny. 

Autorky

E-publication

Terézia Hudáková-Ján Šalagovič-Jozef Židzik

The Textbook of Medical Biology and Genetics for Bachelor's Study Programs is a comprehensive academic resource tailored to the curriculum of undergraduate courses at the Faculty of Medicine, Pavol Jozef Šafárik University in Košice. Each of the 15 chapters begins with a concise theoretical overview, followed by a carefully selected set of practical exercises and model examples designed to promote active learning and critical thinking. This publication aims to serve as an essential companion for students, supporting their understanding of key concepts and enhancing their preparation for coursework and examinations in designated bachelor's programs.

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Martina Zavacká a kolektív

Kniha „DIABETICKÁ NOHA Z POHĽADU CIEVNEHO CHIRURGA“ obsahuje 14 kapitol. Pojednáva o syndróme diabetickej nohy z multidisciplinárneho pohľadu viacerých odborníkov: angiochirurga, diabetológa, chirurga, podiatra, röntgenológa, neurológa a algeziológa. Úvodné kapitoly majú charakter propedeutiky, čo má taktiež význam aj pre pregraduálnu výchovu. Nasledujúce kapitoly sa zaoberajú vznikom syndrómu, výskytom, jeho diagnostikou, terapeutickými postupmi, pridruženými postihnutiami neurologického charakteru, starostlivosťou podiatra a algeziológa pri pretrvávaní bolestí. Ďalšie časti sú vyhradené chirurgickej a endovaskulárnej liečbe tepien cestou cievneho chirurga a intervenčných angiológov. Nezabúdajúc na problematiku amputácií a správnu rehabilitáciu pacientov s diabetom.  V knihe nájdu poučenie cievni chirurgovia, angiológovia, všeobecní chirurgovia, diabetológovia, neurológia, röntgenológovia, podiatri  a všeobecní lekári.

Kniha je zdrojom najnovších teoretických i praktických informácií pre postgraduálnu výchovu vyššie spomenutých odborníkov.

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Mária Frankovičová - Jana Kaťuchová

Dear readers and students,

The book “Surgery for Medical Students“ is a textbook intended to be used by those studying at medical faculties and in other healthcare fields. In this textbook, the authors, encompassing all surgical specialties, have tried to provide the reader with a holistic context of the study material intended to be used in preparation for the state exam from surgery. I thank all the co-authors for their willingness and cooperation. To the students I hope you have a pleasant time reading and studying the book.

Prof. MUDr. Mária Frankovičová, PhD

E-book

Erik Dosedla

A uterine scar is currently a significant medical problem. Uterine scars most commonly occur after a Cesarean section, which is one of the most frequent laparotomic surgeries (Yazicioglu et al., 2006). The frequency of Cesarean sections increased between 1990 and 2014 in the USA from 21.2% to 32.2% (Hamilton et al., 2015), in Great Britain from 12% to 26.2% (NHS Maternity Statistics - England, 2013-14: Summary Report, 2015), and in the Slovak Republic from 8.7% to 31% (Národné centrum zdravotníckych informácii, 2016).

After a Cesarean section (CS), there is a risk of abnormal healing of the uterotomic wound, which can result in the development of certain pathological conditions in consecutive pregnancies (uterine rupture, ectopic pregnancy in the Cesarean scar, placental disorders) (Seow et al., 2004; Oyelese and Smulian, 2006; Fitzpatrick et al., 2012). In addition, a defect in the Cesarean scar is associated with chronic dysmenorrhea, chronic pelvic pain, infertility, and postmenstrual spotting (Wang et al., 2009; Bij de Vaate et al., 2011).

Ultrasound is a valuable examination method in the diagnostic and therapeutic management of these pathological conditions.

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Tatiana Kimáková

Táto vedecká monografia je komplexnou vedeckou prácou zameranou na prítomnosť a pôsobenie ortuti v životnom prostredí, ale aj na rizikové faktory zdravia, ktoré sú s ňou spojené. Monografia predstavuje charakteristiku ortuti v multidisciplinárnom zábere, prezentuje využitie v priemysle a v zdravotníctve, popisuje negatívne vplyvy ortuti v životnom prostredí, na zdravotný stav obyvateľstva. Zároveň prináša návrhy a odporúčania pre rizikové skupiny ľudí. Súčasťou monografie je komplexný výskum koncentrácie ortuti vo vzorkách komodít domácej i zahraničnej produkcie a vo vzorkách rastlín pomocou atómového absorpčného spektrometra AMA 254. Vedecká monografia je vhodná pre vedeckú komunitu, študentov medicínskych, veterinárnych, prírodovedných a poľnohospodárskych odborov ako aj pre študentov verejného zdravotníctva všetkých troch stupňov vysokoškolského štúdia. Monografia je učená aj pre všetkých záujemcov z radov informovanej verejnosti.

Autorka

Ingrid Hodorová - Květuše Lovásová

Publikácia je pokračovaním už vydanej vysokoškolskej učebnice "Ultrasonografická anatómia 1" a dopĺňa ďalšiu medzeru na medicínskom literárnom trhu, týkajúcu sa ultrasonografického pohľadu na periférne nervy a cievy končatín a krku.

E-book

Adriana Boleková a kol.

The book is primarily intended for first-year university students, but it is suitable for anyone who needs to learn. Students can find here the basic principles of learning, principles of how to preserve knowledge, how to concentrate without wasting time, how not to stress before a test or exam and many other practical tips. By acquiring simple knowledge, students will be able to learn effectively with the principles of brain-compatible learning in a way that they will acquire as much information as possible in the shortest period of time with maximum retention; that is minimal forgetting.

The book can serve not only as a theoretical background, but also as a practical tool for mastering university education. The goal was to create a balanced material that would be an interesting source not only for first-year university students, but also for students of higher years and for everyone with a need of lifelong learning.

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Mária Sováriová Soósová, Renáta Suchanová, Libuša Tirpáková

Predkladaná vysokoškolská učebnica prináša poznatky z oblasti ošetrovateľskej starostlivosti u pacientov s ochoreniami srdcovo-cievneho systému. Je určená pre poslucháčov odboru ošetrovateľstvo v rámci pregraduálneho a postgraduálneho vzdelávania, sestrám pracujúcim v tejto oblasti, ako aj ďalším odborníkom z nelekárskych vedných disciplín, ktorí sa zaoberajú starostlivosťou o pacientov s kardio-vaskulárnymi chorobami.

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Adriana Boleková et al.

The book is primarily intended for first-year university students, but it is suitable for anyone who needs to learn. Students can find here the basic principles of learning, principles of how to preserve knowledge, how to concentrate without wasting time, how not to stress before a test or exam and many other practical tips. By acquiring simple knowledge, students will be able to learn effectively with the principles of brain-compatible learning in a way that they will acquire as much information as possible in the shortest period of time with maximum retention; that is minimal forgetting.

The book can serve not only as a theoretical background, but also as a practical tool for mastering university education.

The goal was to create a balanced material that would be an interesting source not only for first-year university students, but also for students of higher years and for everyone with a need of lifelong learning.

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Ingrid Babinská - Monika Halánová

Epidemiológia je samostatný vedný odbor, ktorý sa zaoberá štúdiom procesu vzniku a šírenia ochorení, navrhuje opatrenia na ochranu a zlepšenie zdravia a kontroluje ich účinnosť. Jej hlavným cieľom je prispievať k znižovaniu chorobnosti a úmrtnosti, k ochrane a upevňovaniu zdravia, ako aj k predĺženiu života a zlepšeniu jeho kvality u jednotlivcov a v populácii.

Aj napriek tomu, že dominantné postavenie v celkovej morbidite a mortalite vo vyspelých krajinách majú v súčasnosti chronické neinfekčné ochorenia, epidémie infekčných ochorení sa vyskytujú stále. Dnešná doba so sebou prináša nové hrozby, ktorým musí epidemiológia, ale aj iné vedné odbory (napr. verejné zdravotníctvo, infektológia, cestovná medicína a pod.) čeliť. Ide najmä o infekcie vyvolané novými alebo novo sa objavujúcimi patogénmi, zmeny životného prostredia a životného štýlu, klimatické zmeny, rastúca rezistencia na antibiotiká, odmietanie očkovania, chudoba a pod.

Prvý diel predkladaných učebných textov prináša informácie týkajúce sa epidemiologického vyšetrovania v ohnisku nákazy, prehľad o klasifikácii infekčných chorôb z pohľadu epidemiológa a podrobnejšie sa venuje problematike črevných nákaz. Samostatná kapitola je venovaná modelovým situáciám, ktoré prispejú k pochopeniu danej problematiky a zvládnutiu obdobných situácií priamo v praxi.    

Učebné texty sú prioritne určené študentom bakalárskeho a magisterského štúdia odboru Verejné zdravotníctvo, ale určite si v ňom množstvo informácii nájdu aj študenti Všeobecného lekárstva a študenti ďalších bakalárskych a magisterských odborov Lekárskej fakulty UPJŠ v Košiciach.

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Ladislav Kočan - Dušan Rybár - Róbert Rapčan

The autonomic nervous system is a vital component of the peripheral nervous system, responsible for maintaining homeostasis and regulating internal processes within the body. Unlike the voluntary control exerted by the central nervous system, the autonomic nervous system operates involuntarily, innervating smooth organs, vessels, skin glands, and even exerting some influence over skeletal muscles in connection with vegetative functions such as breathing, digestion, and the urinary and gonadal systems. Its impact extends crucially to the cardiac muscles of the heart and plays a significant role in endocrine and metabolic functions, thermoregulation, as well as emotional and behavioral responses, including adaptive reactions to stressors.

The aim of this publication is to provide a comprehensive and objective exploration of the anatomical and physiological intricacies of the autonomic nervous system, offering insights into its clinical applications. Within these pages, we meticulously delineate various interventional therapeutic procedures tailored to specific diagnoses related to the autonomic nervous system, aligning each intervention with the anatomical framework of the autonomic system. The efficacy of these procedures is evaluated based on the level of evidence, as per the current recommendations of Evidence-Based Medicine.

This publication is primarily crafted for fifth and sixth-year medical students and medical professionals specializing in anesthesiology, intensive care, and pain medicine. It serves as a valuable resource for gaining a deeper understanding of autonomic nervous system function and its clinical implications, facilitating informed decision-making in clinical practice.

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