Laparoskopická hysterektómia

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Terézia Kisková - Stanislav Matéffy - Františka Horváthová

The laboratory rat (Rattus norvegicus) is one of the most commonly used experimental animals. It serves as a model organism for analyzing numerous biological processes and pathological mechanisms, such as cardiovascular diseases, metabolic disorders (e.g., lipid metabolism, diabetes mellitus), neurological and neuropsychiatric conditions (e.g., stroke, epilepsy, or Alzheimer's disease), neurobehavioral research, autoimmune diseases (e.g., arthritis), cancer, and renal diseases. It offers many unique advantages for modeling human diseases, testing drugs and natural substances, and studying responses to environmental factors. The size of the laboratory rat, compared to the mouse, creates ideal conditions for physiological manipulations. Additionally, rats are used in clinical toxicology to test chemical substances (Hedrich, 2000).

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Daniela Filakovská- Shoshana Chovan- Zuzana Dankulincová

Dnes sú to už celé generácie odopierania príležitostí pre napĺňanie potenciálu a storočia diskriminácie, ktoré oberajú deti v marginalizovaných komunitách o detstvo tak ako ho poznáme my ostatní, ktorí sme mali viac „šťastia“. Tak, ako sa generácie ľudí v marginalizovaných komunitách točia v kruhu chudoby, z ktorého niet ľahkej cesty, tak sa aj my točíme v bludnom kruhu hľadania vinníkov a odovzdávania si predsudkov a stereotypov založených na mylných predpokladoch, ktoré sú tak zakorenené a samozrejmé, že mnohých ľudí ani nenapadne o nich pochybovať, spochybňovať ich logiku, či sa snažiť ich vyvracať. Spoločnosť na základe vlastných ideálov s ľahkosťou súdi matky či otcov, že nie sú dosť dobrí. Omnoho ťažšia cesta je však snažiť sa pochopiť, čo im v tom bráni. Povedať, že za stratené detstvo detí v marginalizovaných komunitách môžu rodičia, je príliš zjednodušené a nezohľadňuje to omnoho širší kontext a súvislosti. A práve vplyv tohoto kontextu na raný vývin a hľadanie súvislostí je naším cieľom. Nielen preto, že si uvedomujeme potrebu búrať stereotypy a meniť spoločenský diskurz, no najmä preto, aby sme vedeli priniesť dôkazy, na základe ktorých bude možné tvoriť politiky, smerovať intervencie a pomôcť tak ďalším generáciám detí dosiahnuť na príležitosti, ktoré im umožnia naplniť svoj plný potenciál.

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Marián Sabol - Helga Kostelná - Leonard Siegfried

Cieľom učebných textov je poskytnúť študentom medicíny a príbuzných odborov   poznatky o základných imunologických metódach, ktoré sa využívajú v klinickej praxi. V učebných textoch sú zahrnuté metódy na vyšetrenie fagocytózy, komplementu, imunoglobulínov, autoprotilátok,  HLA molekúl a T lymfocytov.  Súčasťou textov sú aj  postupy pre izoláciu a stanovenie počtu vybraných  typov buniek imunitného systému. Kombinácia klasických  metód (rozetové testy, fluorescenčná mikroskopia) a moderných metód   (napríklad prietoková cytometria a  ELISPOT) umožňuje orientáciu v základných laboratórnych metódach imunológie.

Peter Berek 

S vývojom endovaskulárnej chirurgie dochádza postupne k rozvoju stentingu ACI. Minimálne invazívny prístup spravil túto metodiku vhodnú pre pacientov s vážnymi konkomitatnými kardiálnymi alebo pľúcnymi ochoreniami. Ďalšou výhodou v porovnaní s chirurgickou liečbou bol lepší prístup k ACI u pacientov po rádioterapii, po predchádzajúcich operáciách na krku, ale aj u pacientov so stenózami blízko lebečnej bázy. Porovnanie CEA vs CAS je zaujímavou a diskutabilnou témou mnohých štúdií. Avšak, aj napriek celosvetovému mohutnému rozvoju endovaskulárnej liečby karotická endarterektómia ostáva zlatým štandardom liečby stenózy ACI u symptomatických aj asymptomatických pacientov.

V tejto monografii by sme radi akcentovali a systematizovali problematiku chirurgickej prevencie CMP z pohľadu cievneho chirurga.

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Tatiana Kimáková a kol.

Ethics, as the science of the proper realization of human potential in various areas of life, also extends into the environment. For understanding the ethical aspects in this field, a thorough knowledge of the individual components of the environment, as well as their impact not only on humans but on all living nature, is very important. Therefore, questions concerning the influence of the environment are increasingly at the forefront of interest from an ethical perspective, also in connection with existing legal norms.

The modern process of civilization is characterized by rapid development of science and technology. However, this development, while raising the standard of living on one hand, also brings negative side effects on the other. The result is the disruption of ecological, biological, and natural life conditions, especially in the areas of industrial centers. The development of individual branches of industry leads to the production of liquid, gaseous, and solid wastes, the emergence of harmful risk factors threatening various components of living nature, including humans. There may be increased bioaccumulation of hazardous chemical elements in organisms, which, through their effects, represent a potential risk also in terms of carcinogenesis and mutagenesis.

For this reason, an important role of society is to create conditions to prevent the release of emissions and to reduce their concentration to the lowest possible, socially and biologically acceptable level. The assessment of the biological effects of harmful substances is based on experimental and epidemiological studies. Knowledge of concentration and duration of exposure is crucial for applying dose-effect relationships and for determining the highest permissible concentrations of pollutants. The health of the population, as a universal value and a primary human right, represents a fundamental economic resource not only for the individual, but also for society as a whole.

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Ingrid Babinská - Monika Halánová

Epidemiológia je samostatný vedný odbor, ktorý sa zaoberá štúdiom procesu vzniku a šírenia ochorení, navrhuje opatrenia na ochranu a zlepšenie zdravia a kontroluje ich účinnosť. Jej hlavným cieľom je prispievať k znižovaniu chorobnosti a úmrtnosti, k ochrane a upevňovaniu zdravia, ako aj k predĺženiu života a zlepšeniu jeho kvality u jednotlivcov a v populácii.

Aj napriek tomu, že dominantné postavenie v celkovej morbidite a mortalite vo vyspelých krajinách majú v súčasnosti chronické neinfekčné ochorenia, epidémie infekčných ochorení sa vyskytujú stále. Dnešná doba so sebou prináša nové hrozby, ktorým musí epidemiológia, ale aj iné vedné odbory (napr. verejné zdravotníctvo, infektológia, cestovná medicína a pod.) čeliť. Ide najmä o infekcie vyvolané novými alebo novo sa objavujúcimi patogénmi, zmeny životného prostredia a životného štýlu, klimatické zmeny, rastúca rezistencia na antibiotiká, odmietanie očkovania, chudoba a pod.

Prvý diel predkladaných učebných textov prináša informácie týkajúce sa epidemiologického vyšetrovania v ohnisku nákazy, prehľad o klasifikácii infekčných chorôb z pohľadu epidemiológa a podrobnejšie sa venuje problematike črevných nákaz. Samostatná kapitola je venovaná modelovým situáciám, ktoré prispejú k pochopeniu danej problematiky a zvládnutiu obdobných situácií priamo v praxi.    

Učebné texty sú prioritne určené študentom bakalárskeho a magisterského štúdia odboru Verejné zdravotníctvo, ale určite si v ňom množstvo informácii nájdu aj študenti Všeobecného lekárstva a študenti ďalších bakalárskych a magisterských odborov Lekárskej fakulty UPJŠ v Košiciach.

Ingrid Hodorová - Květuše Lovásová

The publication is a continuation of the already published university textbook"Ultrasound Anatomy 1" and fills the gap in the medical literary market concerning the ultrasound view of peripheral nerves and vessels of the limbs, and neck as well.

 Ingrid Dravecká 

College textbook "Investigation methods in Diabetology" is designed for students of medicine. It can help them in preparing for an exam from internal medicine but specially in preparing for a state exam from internal medicine. The introduction is devoted to classification and diagnostic criteria of diabetes mellitus. Further It describes investigation options (clinical, laboratory, imaging) of different types of diabetes mellitus as well as its acute and chronic complications. At the end there are given diagnostics and classification of the individual components of the metabolic syndrome, obesity and dyslipidemia.

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Jozef Kafka

Behavior, in the slovak language expressed as an intention, belongs to basic mental processes of every individual. In this work I consider it as the basic component of an individual having two sides, outer- and inner side. I present it in the scheme No. 2.

The problem of behavior can not be fully covered, although there is a lot of writing, discussing and experimenting by ancient time.

The work may offer only few comments, approaching maily disorders of behavior. I present the original explanation of these disorders, dividing them on primary and derived ones. Primary disorders create the core of the disorder, derived disorders create a component of other disorders.

My classification of primary disorders is as follows:

1. age dependent disorders of behavior
2. disorders in the dynamical structure and in phases of behavior
3. integrative disorders of behavior, disorders of the will, which is the sign of the developed behavior of the individual.

The work is addresses to everone who is interested in his/her owm behavior, but especially for the Medical faculty and psychiatrists, for students of all our faculties.

Author 

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Mária Sováriová Soósová, Renáta Suchanová, Libuša Tirpáková

Predkladaná vysokoškolská učebnica prináša poznatky z oblasti ošetrovateľskej starostlivosti u pacientov s ochoreniami srdcovo-cievneho systému. Je určená pre poslucháčov odboru ošetrovateľstvo v rámci pregraduálneho a postgraduálneho vzdelávania, sestrám pracujúcim v tejto oblasti, ako aj ďalším odborníkom z nelekárskych vedných disciplín, ktorí sa zaoberajú starostlivosťou o pacientov s kardio-vaskulárnymi chorobami.

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Peter Berek

University scripts “Visceral pathology of vascular origin“analyze one of the most challenging vascular regions, the aorta and the visceral aortic branches, from the surgical perspective. The diagnostic and the treatment aneurysms of the abdominal aorta are dedicated to the first chapter. Early diagnostic and operative treatment is crucial in the treatment of ruptured aneurysms of the abdominal aorta. Shortening of the interval between the patient’s arrival with ruptured aneurysm of the abdominal aorta into the hospital and the beginning of the operation decreased the perioperative mortality. This shortening, together with the use of the cell savers, led to the dropping of perioperative mortality from 50% to 20%. The diagnostics and surgical treatment of the acute and chronic occlusion of the aorta and iliac arteries are analyzed in the second chapter. In this chapter, the focus is given to the aortobifemoral bypass as “the gold standard“ of the surgical therapy of aortoiliac atherosclerosis. The management of acute mesenteric ischemia is the content of the third chapter. Acute mesenteric ischemia is a severe condition with high mortality. The problem of acute mesenterial ischemia is a delayed diagnostic that is the reason for poor therapeutical outcomes of the disease. The possible imagine studies and operations used in treating acute mesenteric ischemia are brought in this chapter. Chronic mesenteric ischemia leads to cachexia. The diagnosis of chronic mesenterial ischemia is one of the most demanding, and surgical therapy used in the treatment of chronic mesenterial ischemia also belongs to the most challenging operations. Left-sided colon ischemia belongs to the severe complications of the aortoiliac reconstructions. Left-sided colon ischemia has a high mortality. In the prevention of the left-sided colon, ischemia is preserving at least one internal iliac artery. The complex diagnostics treatment of intraabdominal compressive syndromes as Dunbar syndróme, „Nutcracker“ syndróme a Wilkie syndróme, analyzed in the last chapter.

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Eva Ďurovcová - Mária Mareková

Clinical Biochemistry - selected chapters - MEFANET >>> 

After 7 years, we finally reworked the textbook on the subject of clinical biochemistry at UPJŠ FM in Košice. We have innovated information in accordance with recommendations of professional medical societies and added new chapters. As the scope of the subject is limited, the textbook does not cover all issues of biochemical diagnostics. It focuses on disorders of water-ion and acid-base balance disorders, and basic laboratory diagnostics of diseases of selected organs.

The textbook of clinical biochemistry has the ambition to become a practical aid for senior medical students and beginning doctors in the study of laboratory medicine. It should make it easier for them to orientate themselves in routinely used clinical-biochemical examinations and could form a springboard for a more detailed studying of laboratory methods and their use in diagnostic and monitoring algorithms.
Like any medical discipline, clinical biochemistry is evolving rapidly and gradually integrating with other areas of laboratory medicine. New diagnostic methods penetrate deeper into the essence of the biochemical mechanisms of the human body, and "omic" methods are gaining ground. It is almost sure that in a few years, laboratory examination looks quite different from today. If this publication quite hypothetically reaches its next edition, many chapters will need to updated, and new chapters written following the up-to-date status.
Authors thanks to their colleagues and reviewers for their professional comments and constructive criticism of the text - prof. Jaroslav Racek, MD, DrSc. from FM UK in Pilsen.
Authors thanks very kindly too prof. MUDr. Dušan Dobrota, CSc. (JFM UK Martin) and doc. MVDr. Zuzana Kostecká, PhD. (UVMP, Košice), who read and wrote review of this textbook.

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 John B. West - Andrej Andrašovský

West’s Respiratory Physiology: The Essentials is the gold standard text for learning respiratory physiology quickly and easily. This highly readable, must-have text serves as an introduction to students and a review for licensing and other exams. The Tenth Edition features the addition of Dr. Andrew M. Luks as co-author along with new clinical vignettes, additional multiple-choice review questions, and updated information on key topics in respiratory physiology, such as blood flow and metabolism, gas transport by the blood, and the physiology of high altitude.

• New! Clinical vignettes with questions emphasize how the physiology described can be applied to clinical situations and reinforce reasoning and critical thinking.
• More than 100 multiple-choice questions with full explanations provide self-testing of key concepts for comprehension and exam preparation.
• Clinical boxes and Key Concepts summaries provide bullet-point reviews.
• Appendices of important equations and answers to all questions are easily referenced.
• Online resources include animations that expand on and clarify challenging topics, an interactivequestion bank, and lectures by Dr. West.

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Martina Šemeláková (ed.)

Proceedings contain abstracts from participants of the scientific conference with international participation under the name: Student scientific international conference GenICa”, supported by the project "Bilateral relations and common knowledge between Slovakia and Iceland research at Universities on the topic "Genomic instability and cancer "GenICa", funded under the EEA and Norwegian 2014-2021 Financial Mechanism Programme (FBR02, bilateral initiatives under the Fund for Bilateral Relations at national level co-financed by EEA and Norwegian Financial Mechanism 2014-2021) which took place on 19 - 21 June 2024 in the premises of Hotel Sorea Trigan, Štrbské Pleso, Slovakia.

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Alžbeta Blichárová - Ľudmila Verbóová - Zuzana Benetinová - Vladimír Tancoš  - Patrícia Kollárová  - Adam Nedoroščík - Erika Štammová  - Pavel Kočan

„Patológia 2. časť (letný semester) - Praktické cvičenia pre študentov všeobecného lekárstva“ je druhou časťou vysokoškolskej učebnice predstavujúcou druhú polovicu výučby (letný semester). V tejto časti je popísaných 70 diagnóz, kde každej je venovaná jedna strana. V popise je uvedené poradové číslo zhodujúce sa s číslom preparátu a názov danej diagnózy. Študent sa pri každom preparáte oboznámi so základnými informáciami o danej chorobe, jej makroskopickým a mikroskopickým obrazom. Navyše je vytvorené miesto, v ktorom si študent môže zaznačiť (nakresliť) charakteristický mikroskopický obraz danej choroby. Preparáty v tejto učebnici sú zamerané na špeciálnu patológiu – patológiu pľúc, hematopatológiu, patológiu gastrointestinálneho, urogenitálneho systému, prsníka, endokrinného, pohybového  a nervového systému, kože, novorodeneckého a detského veku.

Tým, že učebnica umožňuje preparáty zakresľovať, vytvára študentom priestor pre trvalejšie zapamätanie si danej problematiky. Je vynikajúcim zdrojom pre prípravu študentov na kolokvium a ústnu skúšku.

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Jaroslav Majerník - Andrea Kačmariková

The university textbook "Databases in MS Access - accompanying texts for practical exercises" is intended for students of medical faculties, students of non-technical universities and all beginners in working with databases. It introduces the reader to the issue of database data processing and explains the basic principles that need to be known when creating relational databases. It is therefore suitable for those who have not yet worked with databases, or who have started thinking about managing their data using their own database.

However, even more "experienced" computer users can find useful information here. The university textbook is written in the way that its content can be mastered with basic knowledge of working with computers and programs running in the environment of MS Windows operating system.

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