História univerzitnej nemocnice Louisa Pasteura v Košiciach

Marián Sabol - Helga Kostelná - Leonard Siegfried

Cieľom učebných textov je poskytnúť študentom medicíny a príbuzných odborov   poznatky o základných imunologických metódach, ktoré sa využívajú v klinickej praxi. V učebných textoch sú zahrnuté metódy na vyšetrenie fagocytózy, komplementu, imunoglobulínov, autoprotilátok,  HLA molekúl a T lymfocytov.  Súčasťou textov sú aj  postupy pre izoláciu a stanovenie počtu vybraných  typov buniek imunitného systému. Kombinácia klasických  metód (rozetové testy, fluorescenčná mikroskopia) a moderných metód   (napríklad prietoková cytometria a  ELISPOT) umožňuje orientáciu v základných laboratórnych metódach imunológie.

Silvia Timková - Marcel Riznič - Jozef Minčík 

 Eugen Ďurovič - Peter Kizek

Vysokoškolský učebný text Ochorenia jazyka sa zameriava na anomálie a choroby postihujúce jazyk.  V jednotlivých kapitolách opisuje vrodené stavy, s ktorými sa na jazyku stretávame, ich diagnostiku ako aj možnosti liečby, ako aj jednotlivé samostatné chorobné jednotky. Úvodnú kapitolu tvoria lokálne ochorenia jazyka, kedy ochorenie nemá prejavy na iných ústnych slizniciach. Ďalšou skupinou sú ochorenia, kde je symptomatológia choroby prítomná na jazyku, ale aj na ostatných ústnych slizniciach. Okrem týchto stavov vznikajúcich priamo v ústnej dutine sú v ďalších kapitolách rozobraté stavy, kde celkové ochorenia, akými sú infekčné, endokrinologické, krvné a dermatologické ochorenia vyvolávajú zmeny na jazyku. Samostatné kapitoly sú venované prekanceróznym stavom a benígnym a tumoriformným léziam.  Poslednú kapitolu tvoria ochorenia jazyka u detskej populácie.

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Jaroslava Kopčáková

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Erik Dosedla

A uterine scar is currently a significant medical problem. Uterine scars most commonly occur after a Cesarean section, which is one of the most frequent laparotomic surgeries (Yazicioglu et al., 2006). The frequency of Cesarean sections increased between 1990 and 2014 in the USA from 21.2% to 32.2% (Hamilton et al., 2015), in Great Britain from 12% to 26.2% (NHS Maternity Statistics - England, 2013-14: Summary Report, 2015), and in the Slovak Republic from 8.7% to 31% (Národné centrum zdravotníckych informácii, 2016).

After a Cesarean section (CS), there is a risk of abnormal healing of the uterotomic wound, which can result in the development of certain pathological conditions in consecutive pregnancies (uterine rupture, ectopic pregnancy in the Cesarean scar, placental disorders) (Seow et al., 2004; Oyelese and Smulian, 2006; Fitzpatrick et al., 2012). In addition, a defect in the Cesarean scar is associated with chronic dysmenorrhea, chronic pelvic pain, infertility, and postmenstrual spotting (Wang et al., 2009; Bij de Vaate et al., 2011).

Ultrasound is a valuable examination method in the diagnostic and therapeutic management of these pathological conditions.

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Peter Berek

University scripts “Visceral pathology of vascular origin“analyze one of the most challenging vascular regions, the aorta and the visceral aortic branches, from the surgical perspective. The diagnostic and the treatment aneurysms of the abdominal aorta are dedicated to the first chapter. Early diagnostic and operative treatment is crucial in the treatment of ruptured aneurysms of the abdominal aorta. Shortening of the interval between the patient’s arrival with ruptured aneurysm of the abdominal aorta into the hospital and the beginning of the operation decreased the perioperative mortality. This shortening, together with the use of the cell savers, led to the dropping of perioperative mortality from 50% to 20%. The diagnostics and surgical treatment of the acute and chronic occlusion of the aorta and iliac arteries are analyzed in the second chapter. In this chapter, the focus is given to the aortobifemoral bypass as “the gold standard“ of the surgical therapy of aortoiliac atherosclerosis. The management of acute mesenteric ischemia is the content of the third chapter. Acute mesenteric ischemia is a severe condition with high mortality. The problem of acute mesenterial ischemia is a delayed diagnostic that is the reason for poor therapeutical outcomes of the disease. The possible imagine studies and operations used in treating acute mesenteric ischemia are brought in this chapter. Chronic mesenteric ischemia leads to cachexia. The diagnosis of chronic mesenterial ischemia is one of the most demanding, and surgical therapy used in the treatment of chronic mesenterial ischemia also belongs to the most challenging operations. Left-sided colon ischemia belongs to the severe complications of the aortoiliac reconstructions. Left-sided colon ischemia has a high mortality. In the prevention of the left-sided colon, ischemia is preserving at least one internal iliac artery. The complex diagnostics treatment of intraabdominal compressive syndromes as Dunbar syndróme, „Nutcracker“ syndróme a Wilkie syndróme, analyzed in the last chapter.

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Lucia Dimunová - Jana Raková - Gabriela Štefková

 Ingrid Schusterová 

To offer our medical students of 5th and 6th classes as well as to professional public (pediatrics, pediatric cardiologists) integrated information from pediatric cardiology, which is based on scientific knowledge of experts and practical requirements including our experiences. The publication will extend given the discipline of cardiovascular risk factors of cardiovascular heart disease and acquired heart diseases, which are more actual at the present time in the children as we as bring the new didactic methods in pediatric cardiology teaching.

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Andrea Madarasová Gecková - Daniela Husárová   a kol.

National Report on the Health and Health-Related Behaviour of 11-, 13-, and 15-Year-Old Schoolchildren Based on the Survey Conducted in 2021/2022 within the International Project “Health Behaviour in School-aged Children” (HBSC)

For several years, this study has provided us with key insights for a better understanding of the health-related behaviour of our young people. It examines a range of health-related topics such as sleep, mental well-being, nutritional behaviour, and physical activity. Important areas of research also include school and social relationships within it, family and family background, as well as peer relationships.

The findings deepen our understanding of the mechanisms influencing differences and changes in young people’s health and risk behaviours. They are crucial for the development of effective health promotion programmes and health-related behavioural interventions, educational programmes in this field, and for monitoring their effectiveness—not only at the national but also at the international level. The knowledge gained is important for a better understanding of the needs of schoolchildren and for adapting services and systemic support so that these needs are taken into account to the greatest possible extent in today’s rapidly changing world. The study can help us understand the impact of the COVID-19 pandemic on the quality of both mental and physical health.

The pandemic and the related epidemiological and hygiene measures aimed at limiting the spread of the virus have meant significant restrictions in the daily lives of people of all ages—including children and adolescents. The standard educational process, social contact with peers, extracurricular activities, and other interests both in and out of school were severely disrupted, which had a significant impact on the experiences of schoolchildren.

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Mária Mareková  et al.

Predmet Lekárska biochémia plní v medicínskom štúdiu nezastupiteľnú úlohu, naučiť študentov vnímať prirodzené, fyziologické, ako aj chorobné procesy v organizme ako deje odohrávajúce sa na molekulovej úrovni. Na rozlíšenie patologických pochodov od normálnych je potrebné zvládnuť a pochopiť zmysel obrovského množstva biochemických reakcií prebiehajúcich v bunke (bunkový metabolizmus). Osvojenie si týchto faktov je hlavným cieľom predmetu Lekárska biochémia, ktorého zvládnutie je dobrým základom pre štúdium patobiochémie, fyziológie a klinickej biochémie, ako aj mnohých ďalších odborných predmetov medicínskeho štúdia. Pre lepšie zvládnutie a pochopenie biochemických procesov sme pre študentov pripravili vysokoškolskú učebnicu „Lekárska biochémia – Semináre“, ktorá poskytuje študentom okrem teoretických úvodov aj prehľadné schémy procesov a mnoho otázok, vypracovanie ktorých by malo študentom uľahčiť prípravu na skúšku.

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Eva Szabóová

The publication "Fundamentals of Cardiovascular Risk Assessment: Tools and Applications" is the first of its kind in Slovakia. It was created with the aim of providing healthcare professionals, medical students, and anyone interested in the subject with a clear, practical overview of cardiovascular risk. The book presents a global and national picture of mortality, emphasizes the importance of prevention and screening, and introduces the basic principles of risk assessment. Special attention is paid to risk factors and modifiers that can significantly change a patient's prognosis. For a better understanding of the issue, the reader will also find chapters devoted to clinical conditions, an overview of scoring systems, risk categories, and finally practical examples from clinical practice that link theory with everyday medical reality. Our goal is for this book to be not only an educational tool, but also a practical guide for decision-making in clinical practice. We believe that it will contribute to a better understanding of the complexity of cardiovascular risk and at the same time help to strengthen the emphasis on prevention, which remains the most effective tool in the fight against these diseases.

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Kvetoslava Rimarová a kol.

Učebnica poskytuje komplexný a interdisciplinárny pohľad na problematiku humánnej výživy v kontexte verejného zdravotníctva, hygieny výživy a prevencie ochorení. Je koncipovaná ako základný aj rozširujúci študijný materiál pre študentov zdravotníckych, biomedicínskych a verejno-zdravotníckych odborov, ako aj pre odborníkov pôsobiacich v oblasti výživy, hygieny, potravinárstva a zdravotnej politiky. Publikácia systematicky pokrýva všetky kľúčové oblasti výživy človeka – od základných zložiek potravy (bielkoviny, sacharidy, tuky, vitamíny, minerálne látky), ich biologickej a energetickej hodnoty, cez odporúčané výživové dávky a tvorbu racionálneho jedálnička, až po hodnotenie nutričného stavu populácie. Osobitná pozornosť je venovaná antioxidantom, probiotikám a funkčným potravinám, ktoré predstavujú moderný a dynamicky sa rozvíjajúci segment výživovej vedy.

Učebnica reflektuje aktuálne trendy v stravovaní vrátane alternatívnych spôsobov výživy, prerušovaného pôstu, vysokoproteínových diét a konzumácie spracovaných a ultraprocesovaných potravín, pričom ich hodnotí z hľadiska vedeckých dôkazov, zdravotných prínosov aj rizík. Dôležitou súčasťou je problematika cudzorodých látok v potravinách, potravinárskych aditív a legislatívnych rámcov ich používania, ako aj význam pitnej vody, jej kvalita, úprava a zdravotné riziká spojené s kontamináciou. Publikácia sa venuje aj špecifickým oblastiam, ako sú alimentárne nákazy, výživa v jednotlivých vývinových obdobiach detí, nemocničné stravovanie a diétne systémy.

Praktickú hodnotu učebnice zvyšuje zaradenie metodicky spracovanej praktickej časti zameranej na mikrobiologické hodnotenie pokrmov rýchleho občerstvenia, založenej na reálnych dátach regionálnych úradov verejného zdravotníctva. Text je spracovaný prehľadne, s využitím tabuliek, obrázkov a aktuálnej odbornej literatúry, čo umožňuje čitateľovi nielen osvojenie teoretických poznatkov, ale aj ich aplikáciu v praxi. Učebnica predstavuje ucelený, moderný a vedecky podložený zdroj poznatkov o výžive ako jednom zo základných determinantov zdravia populácie.

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Pavol Joppa a kol.

University textbooks address the etiopathogenesis, clinical presentation, diagnosis, differential diagnosis, treatment, complications, and prognosis of the most significant non-specific respiratory diseases, including bronchial asthma, chronic obstructive pulmonary disease (COPD), pneumonias, pleural syndrome, lung cancer, interstitial lung diseases (including exogenous allergic alveolitis and sarcoidosis), and sleep apnea syndrome.

The final section on non-specific diseases discusses chronic cor pulmonale as the primary cardiovascular complication of chronic pulmonary diseases.

The last chapter focuses on the etiopathogenesis, diagnosis, treatment, and prevention of pulmonary and extrapulmonary forms of tuberculosis, addressing the scope of phthisiology

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Zora Lazúrová

This publication is intended for medical students and offers a systematic overview of anemia from the perspective of clinical practice. The publication includes a classification of anemias based on pathophysiological mechanisms, including impaired red blood cell production, increased destruction and blood loss. It provides detailed description of iron, vitamin B12, and folic acid deficiencies, as well as aplastic and hemolytic anemias, including some of the rare hereditary forms. The text features chapters on laboratory diagnostics, investigative methods, and interpretation of results. The publication is focused on clinical presentation, differential diagnostic approach, and the basic principles of treatment for each type of anemia. The material is supplemented with images and tables to help in the understanding of this complex topic. The fundamentals of clinical management are presented in schematic differential diagnostic algorithms. The aim of this publication is to provide a clear, didactically structured, and practically oriented resource that supports the teaching of internal medicine. It is suitable not only for exam preparation, but also as an introduction to the clinical practice.

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Darina Kluchová 

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Ján Kučera - Eva Kovaľová - Juraj Strecha

Peri-implantation diseases such as peri-implantitis and mucositis have a wide range of prevalence. Several etiological factors and the interaction of risk factors influence their onset and development. Careful investigation determines the diagnosis and subsequent treatment. Treatment, depending on the condition, is either non-surgical or surgical. Systematic postoperative care, a recall system, and patient instruction and cooperation are essential, which create the preconditions for successful implant treatment.

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Jozef Kafka

Behavior, in the slovak language expressed as an intention, belongs to basic mental processes of every individual. In this work I consider it as the basic component of an individual having two sides, outer- and inner side. I present it in the scheme No. 2.

The problem of behavior can not be fully covered, although there is a lot of writing, discussing and experimenting by ancient time.

The work may offer only few comments, approaching maily disorders of behavior. I present the original explanation of these disorders, dividing them on primary and derived ones. Primary disorders create the core of the disorder, derived disorders create a component of other disorders.

My classification of primary disorders is as follows:

1. age dependent disorders of behavior
2. disorders in the dynamical structure and in phases of behavior
3. integrative disorders of behavior, disorders of the will, which is the sign of the developed behavior of the individual.

The work is addresses to everone who is interested in his/her owm behavior, but especially for the Medical faculty and psychiatrists, for students of all our faculties.

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