Laparoskopická hysterektómia

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Eva Slabá-Helena Mičková-Jozef Židzik-Lucia Klimčáková-Janka Vašková

Teaching texts „Practical Lessons in Medical biology“ provide the theoretical foundations of microscopy, various microscopic techniques and preparation of microscopic slides in an understandable form. The chapters of the teaching texts contain model questions and tasks from cytology, molecular biology and genetics enabling students to acquire new knowledge from individual thematic areas and provide instructions for the implementation of tasks during laboratory lessons in medical biology. Teaching texts are primarily intended for the practical lessons in the subjects Biology 1 and Biology 2 for foreign students of the first year of General Medicine and the subjects Medical Biology and Genetics and Regenerative Medicine for foreign students of the first and second year of Dental Medicine at P. J. Šafárik University in Košice – Faculty of Medicine.

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Lucia Bosáková - Zuzana Dankulincová - Daniela Fiľakovská

Publication called Scientific communication and management of research projects serves as background and teaching material. Its aim is to help university students and researchers develop competencies important for scientific work, such as scientific integrity, critical work with literary sources, management of research projects and scientific communication. Publication is divided into four parts.

The first part is focused on the preparation of a research project, where it is important to know the basic ethical principles applied in the research project, but also to be able to critically assess literary sources and process them. In the second part, it provides information on the preparation of research projects and their management, including their financing, from preparation and planning, through initialization to implementation, management, logistics, monitoring, evaluation and termination. The third part pays attention to the preparation, processing and presentation of scientific results in the form of a scientific article, presentation, poster or press release, thus covering not only a professional but also a lay audience.

The final fourth part provides information about communication with a scientific journal, whether it is the process of sending, revising an article up to its publication, or the process of assessing scientific work by scientific journal editors in the process of screening and peer review.

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Vincent Nagy

Predkladaná monografia sa komplexne venuje problematike urolitiázy. Má 19 kapitol, ktoré zahrňujú celú šírku problematiky urolitiázy a to epidemiológiu, etiológiu, typy konkrementov, osobitné situácie pri urolitiáze, diagnostiku urolitiázy, zobrazovacie vyšetrovacie metódy pri urolitiáze, konzervatívnu liečbu urolitiázy, chirurgické a endoskopické metódy liečby urolitiázy, metafylaxiu konkrementov a konkrementy v močovom mechúri. V monografii sa zdôrazňuje význam individuálneho rozhodovania o optimálnom spôsobe liečby. Do úvahy sa berie veľkosť konkrementov, ich počet, lokalizácia, anatomické predpoklady a röntgenologické charakteristiky. Pri plánovaní aktívnej liečby sa zdôrazňuje význam resp. potreba zobrazovacími metódami vyšetriť aj anatómiu vývodných močových ciest. Nezastupiteľné miesto, najmä v prípadoch viacpočetnej a opakujúcej sa urolitiázy a geneticky podmienenej urolitiázy, má kompletné metabolické vyšetrenie. Dokumentuje všetky moderné spôsoby diagnostiky a liečby urolitázy. Metodicky opisuje liečbu urolitiázy – akútny management pri renálnej kolike, pri urosepse pri konkrementom zablokovanej obličke a v tehotenstve. Prevažná väčšina pacientov s urolitiázou je liečená farmakologicky a semininvazívnymi technikami. Vychádza sa z vlastných skúseností, komentuje využitie extrakorporálnej litotripsie, endoskopických metód, stentov. Monografia venuje pozornosť aj auxiliárnym metódam, ktoré sa používajú v liečbe urolitiázy, liečbe sprievodnej infekcie, poranení obličiek a močových ciest, poranení okolitých orgánov, rôznych spôsobov derivácie moču, krvácania. V závere sú spomenuté kalcifikácie pri obličkových tumoroch.

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Peter Berek

With the development of endovascular surgery, there is a gradual advancement in ACI stenting. The minimally invasive approach has made this methodology suitable for patients with serious concomitant cardiac or pulmonary diseases. Another advantage compared to surgical treatment was better access to the ICA in patients after radiotherapy, after previous neck surgeries, as well as in patients with stenoses close to the skull base.

The comparison of CEA vs CAS is an interesting and debatable topic in many studies. However, despite the massive global development of endovascular treatment, carotid endarterectomy remains the gold standard for treating ICA stenosis in both symptomatic and asymptomatic patients. In this monograph, we would like to accentuate and systematize the issue of surgical stroke prevention from the perspective of a vascular surgeon.

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Ján Kučera - Eva Kovaľová - Juraj Strecha

Peri-implantation diseases such as peri-implantitis and mucositis have a wide range of prevalence. Several etiological factors and the interaction of risk factors influence their onset and development. Careful investigation determines the diagnosis and subsequent treatment. Treatment, depending on the condition, is either non-surgical or surgical. Systematic postoperative care, a recall system, and patient instruction and cooperation are essential, which create the preconditions for successful implant treatment.

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Libuša Tirpáková - Mária Sováriová Soósová a kol.

It is expected that nurses and professionals working in healthcare will be able to perform various specialized procedures, or assist with selected procedures, skillfully, confidently, and safely.

The university textbook of Nursing Techniques guides students through the most commonly performed nursing activities, reflecting the latest knowledge from the profession, evidence-based practice, and professional guidelines. A significant aspect of this publication is its emphasis on patient individuality and involvement in the planning and implementation of procedures, as well as the prevention of complications and the consistent performance of nursing interventions in accordance with the latest professional and scientific knowledge.

The textbook is divided into twelve chapters. In the introductory chapters, the authors address the organization of the nursing unit and infection control in healthcare facilities. Further chapters are devoted to patient assessment, especially vital functions, nutritional care, preparation and administration of various forms of medication, collection of biological material, care of urinary and bowel elimination, nurse assistance during punctures, wound care, and electrocardiographic examination.

The main aim is to address primarily nursing students, but also students of general and dental medicine and selected healthcare disciplines. We believe that both students and professionals will find in this textbook a guide and a practical assistant.

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Vladimíra Tomečková

Nature, as well as the human body, contains an abundant quantity of organic molecules. This textbook describes selected oxygen, sulfur, nitrogen derivatives of hydrocarbons, heterocyclic compounds of their reactions, which are important in the human body or are found in pharmaceutical active substances, poisons, foodstuffs and heat-treated food. The last part of the textbook describes the isomerism of organic compounds, which enables dynamic changes in the structure of molecules that have different properties. Nature is filled with different plants and animals and is the first laboratory to produce bioactive organic natural compounds. These compounds are compatible with human cells and are applicable as therapeutic medicine. There is an effort to reproduce natural molecules in chemical laboratories, but they cannot be as perfect as the natural ones. Synthetic molecules can serve as a model for multiple studies, but there still does not exist a magic panacea pill or a perfect copy of nature, for the treatment of various diseases. Knowledge about the regenerative and toxic effect of medicinal substances in dependence on their structure (type and number of substituents) is very important for the understanding of their role in modulation of health and disease in dependence on their concentration. Compounds can be used daily only in recommended doses (higher doses can be toxic), but still will not replace a healthy diet. People need a varied diet to be healthy, in which are all necessary nutrients, what Hippocrates demonstrated long ago “Let food be the medicine, and let medicine be the food.” This book is written for students who select bioorganic chemistry subject during the study of general medicine or dentistry as well as for motivated students who would like to practice their knowledge and wish to improve in this subject and for students who would like to learn simplified basic organic reactions with their future application in biochemistry. Learn the simple models mainly through creative simple instruction by using different colours, by repetition, practice by drawing of formulas by hand (at least three times) and memorization of common names of compounds and their reactions which have application in biochemistry. Thus, establishing simple educational methods how to distinguish organic molecules according to the colours of a functional group can promote universal learning for all students who thought that chemistry is a difficult subject, but hopefully they change their opinion after study of this book.

Keywords: organic molecules, oxygen, sulfur, nitrogen derivatives of hydrocarbons, heterocyclic compounds, chemical reactions, isomerism of organic compounds

Želmíra Macejová - Mundher Abdulkareem Salman Aljubouri

         Vysokoškolský učebný text: “ Selected  Rheumatology Topics for Medical Students“ je určený pre študentov lekárskych fakúlt študujúcich v anglickom jazyku v študijnom odbore: General medicine a Dental medicine. Rozsahom sú vhodné pre   pregraduálne štúdium predmetu  interná medicína 5.  Kapitoly uvedené v danom diele zahŕňajú základy reumatológie,  postačujúce  pre absolventov LF UPJŠ.

        Text je prehľadne rozčlenený na :  základné   vyšetrovacie metódy, rozdelenie chorôb na autoimunitné, infekčné artritídy, kryštálmi indukované artritídy,  nezápalové ochorenia v reumatológii, metabolické ochorenia kostí. Obsahom kapitol sú aj najnovšie liečebné možnosti daných ochorení.  V závere je obrazová príloha k ochoreniam spomínaným v samotnom texte.

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Jana Mašlanková

Colorectal carcinoma is the most common malignant tumor of the digestive system, and its rising incidence in Slovakia—particularly among the male population—is alarming. Although significant progress has been made in the diagnosis, screening, and treatment of patients with advanced colorectal cancer, therapeutic options remain limited, necessitating the discovery of additional markers to serve as prognostic predictors.

This monograph aims to draw the attention of the professional community to the critical role and significance of the TGF-β signaling pathway in the initiation, progression, and treatment of colorectal carcinoma. A substantial portion of the text focuses on lesser-known emerging trends and ongoing clinical trials for colorectal cancer patients.

The monograph aspires to provide a balanced resource that serves as an engaging informational tool not only for specialist physicians but also for medical faculty students. By integrating novel insights and clinical data, it seeks to bridge gaps in current understanding and highlight potential avenues for future research and therapy.

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Jozef Radoňak a kol.

Skriptá chirurgická propedeutika predstavujú učebné texty prinášajúce pohl'ad do histórie chirurgie cez všeobecne platné princípy chirurgie, moderné diagnostické a terapeutické metó­dy. Patričná pozornost' sa venuje základom chirurgickej onkológie, úrazovej chirurgie, anesteziológie a resuscitácie ako aj liečbe krvácania, infekcie, šoku či transplantáciám. Súčas­ťou textu sú aj kapitoly z vojnovej chirurgie.

Alžbeta Blichárová a kolektív

“Pathology Part 1 (winter semester) - Practical lessons for students of general medicine” represents the first half of the university textbook designed for the pregradual study of pathology. The textbook complements the lectures of pathology and serves as a source of information for students of general medicine, that are preparing for the practical as well as the final oral examination.

In this part of the “Pathology” series, seventy selected histopathological slides are presented. Each selected slide is provided with general information in relation to etiology and pathogenesis of the disease, as well as with corresponding morphological features, including the gross appearance and the most important histopathological characteristics. The textbook summarizes the basic concepts of general pathology that are necessary to master the broad field of systemic pathology in the second semester.

Keywords: general pathology – histopathological slides – general medicine – gross appearance – microscopic image

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Pavol Jarčuška - Daniel Pella - Ján Rosocha (eds.)

Proceedings of lectures from thematic conferences organized by UVP MediPark

UVP Medipark – the path to innovation in research, diagnostics, and treatment – was the title of the conference held on Tuesday, May 29, 2018, at the premises of the Faculty of Medicine, Pavol Jozef Šafárik University in Košice. The patronage of the event was taken over by the rector of UPJŠ, Prof. RNDr. Pavol Sovák, CSc. The conference program was divided into two main areas – Innovative scientific technologies, clinical research, and the path to the development of new drugs, and UVP Medipark – main research areas.

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Ladislav Kočan - Dušan Rybár - Róbert Rapčan

The autonomic nervous system is a vital component of the peripheral nervous system, responsible for maintaining homeostasis and regulating internal processes within the body. Unlike the voluntary control exerted by the central nervous system, the autonomic nervous system operates involuntarily, innervating smooth organs, vessels, skin glands, and even exerting some influence over skeletal muscles in connection with vegetative functions such as breathing, digestion, and the urinary and gonadal systems. Its impact extends crucially to the cardiac muscles of the heart and plays a significant role in endocrine and metabolic functions, thermoregulation, as well as emotional and behavioral responses, including adaptive reactions to stressors.

The aim of this publication is to provide a comprehensive and objective exploration of the anatomical and physiological intricacies of the autonomic nervous system, offering insights into its clinical applications. Within these pages, we meticulously delineate various interventional therapeutic procedures tailored to specific diagnoses related to the autonomic nervous system, aligning each intervention with the anatomical framework of the autonomic system. The efficacy of these procedures is evaluated based on the level of evidence, as per the current recommendations of Evidence-Based Medicine.

This publication is primarily crafted for fifth and sixth-year medical students and medical professionals specializing in anesthesiology, intensive care, and pain medicine. It serves as a valuable resource for gaining a deeper understanding of autonomic nervous system function and its clinical implications, facilitating informed decision-making in clinical practice.

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Terézia Kisková - Stanislav Matéffy - Františka Horváthová

The laboratory rat (Rattus norvegicus) is one of the most commonly used experimental animals. It serves as a model organism for analyzing numerous biological processes and pathological mechanisms, such as cardiovascular diseases, metabolic disorders (e.g., lipid metabolism, diabetes mellitus), neurological and neuropsychiatric conditions (e.g., stroke, epilepsy, or Alzheimer's disease), neurobehavioral research, autoimmune diseases (e.g., arthritis), cancer, and renal diseases. It offers many unique advantages for modeling human diseases, testing drugs and natural substances, and studying responses to environmental factors. The size of the laboratory rat, compared to the mouse, creates ideal conditions for physiological manipulations. Additionally, rats are used in clinical toxicology to test chemical substances (Hedrich, 2000).

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 Soňa Grešováa kol.

The object of the practical textbook is both theory and practice. The student is familiar with the investigative methods used in patients at different clinics as well as research institutes. Investigative methods are a source of knowledge about the state of the internal environment of an individual, the functionality of the various systems of the body, based on which it is possible to establish a conclusion on whether the individual is healthy or not. 

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Tatiana Kimáková - Štefan Tóth - Ivan Uher

The scientific monograph is devoted to active and healthy aging, its basic indicators, involutional changes, or the relationship between healthy aging and lifestyle. Adopting a healthy lifestyle and actively participating in health care for yourself are important elements in all stages of our lives, and therefore in healthy aging. We describe the possibilities of older people to slow down the adverse changes associated with aging through education and educational activities of various types.

The scientific monograph also includes our own research focused on overall health and selected lifestyle risk factors, especially consumption of various food groups, smoking, alcohol, physical activity and stress of participants at the University of the Third Age at Pavol Jozef Šafárik University in Košice, Slovak and foreign university students at the Medical Faculty of the Pavol Jozef Šafárik University in Košice. The scientific monograph is appropriate for the scientific community, students of medical and natural sciences, public health for all three degrees of university study.

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