English
E-book
Eva Ďurovcová - Mária Mareková
After 7 years, we finally reworked the textbook on the subject of clinical biochemistry at UPJŠ FM in Košice. We have innovated information in accordance with recommendations of professional medical societies and added new chapters. As the scope of the subject is limited, the textbook does not cover all issues of biochemical diagnostics. It focuses on disorders of water-ion and acid-base balance disorders, and basic laboratory diagnostics of diseases of selected organs.
The textbook of clinical biochemistry has the ambition to become a practical aid for senior medical students and beginning doctors in the study of laboratory medicine. It should make it easier for them to orientate themselves in routinely used clinical-biochemical examinations and could form a springboard for a more detailed studying of laboratory methods and their use in diagnostic and monitoring algorithms.
Like any medical discipline, clinical biochemistry is evolving rapidly and gradually integrating with other areas of laboratory medicine. New diagnostic methods penetrate deeper into the essence of the biochemical mechanisms of the human body, and "omic" methods are gaining ground. It is almost sure that in a few years, laboratory examination looks quite different from today. If this publication quite hypothetically reaches its next edition, many chapters will need to updated, and new chapters written following the up-to-date status.
Authors thanks to their colleagues and reviewers for their professional comments and constructive criticism of the text - prof. Jaroslav Racek, MD, DrSc. from FM UK in Pilsen.
Authors thanks very kindly too prof. MUDr. Dušan Dobrota, CSc. (JFM UK Martin) and doc. MVDr. Zuzana Kostecká, PhD. (UVMP, Košice), who read and wrote review of this textbook.
Data sheet
Marián Sabol - Helga Kostelná - Leonard Siegfried
Cieľom učebných textov je poskytnúť študentom medicíny a príbuzných odborov poznatky o základných imunologických metódach, ktoré sa využívajú v klinickej praxi. V učebných textoch sú zahrnuté metódy na vyšetrenie fagocytózy, komplementu, imunoglobulínov, autoprotilátok, HLA molekúl a T lymfocytov. Súčasťou textov sú aj postupy pre izoláciu a stanovenie počtu vybraných typov buniek imunitného systému. Kombinácia klasických metód (rozetové testy, fluorescenčná mikroskopia) a moderných metód (napríklad prietoková cytometria a ELISPOT) umožňuje orientáciu v základných laboratórnych metódach imunológie.
S vývojom endovaskulárnej chirurgie dochádza postupne k rozvoju stentingu ACI. Minimálne invazívny prístup spravil túto metodiku vhodnú pre pacientov s vážnymi konkomitatnými kardiálnymi alebo pľúcnymi ochoreniami. Ďalšou výhodou v porovnaní s chirurgickou liečbou bol lepší prístup k ACI u pacientov po rádioterapii, po predchádzajúcich operáciách na krku, ale aj u pacientov so stenózami blízko lebečnej bázy. Porovnanie CEA vs CAS je zaujímavou a diskutabilnou témou mnohých štúdií. Avšak, aj napriek celosvetovému mohutnému rozvoju endovaskulárnej liečby karotická endarterektómia ostáva zlatým štandardom liečby stenózy ACI u symptomatických aj asymptomatických pacientov.
V tejto monografii by sme radi akcentovali a systematizovali problematiku chirurgickej prevencie CMP z pohľadu cievneho chirurga.
E-book
A uterine scar is currently a significant medical problem. Uterine scars most commonly occur after a Cesarean section, which is one of the most frequent laparotomic surgeries (Yazicioglu et al., 2006). The frequency of Cesarean sections increased between 1990 and 2014 in the USA from 21.2% to 32.2% (Hamilton et al., 2015), in Great Britain from 12% to 26.2% (NHS Maternity Statistics - England, 2013-14: Summary Report, 2015), and in the Slovak Republic from 8.7% to 31% (Národné centrum zdravotníckych informácii, 2016).
After a Cesarean section (CS), there is a risk of abnormal healing of the uterotomic wound, which can result in the development of certain pathological conditions in consecutive pregnancies (uterine rupture, ectopic pregnancy in the Cesarean scar, placental disorders) (Seow et al., 2004; Oyelese and Smulian, 2006; Fitzpatrick et al., 2012). In addition, a defect in the Cesarean scar is associated with chronic dysmenorrhea, chronic pelvic pain, infertility, and postmenstrual spotting (Wang et al., 2009; Bij de Vaate et al., 2011).
Ultrasound is a valuable examination method in the diagnostic and therapeutic management of these pathological conditions.
Download e-book for free (pdf)
E-book
I. R. Mavlyanov - A. K. Ashirmetov - Z. I. Mavlyanov - G. J. Jarilkasinova
Need of carrying out a pharmacological genotyping for providing the individualized pharmacotherapy is shown in the monograph based on the analysis of own and literary data of the central link of drug pharmacokinetics– systems of cytochrome P-450, taking into account its genetic polymorphysm.
The monograph is intended for the clinical pharmacologists, geneticists and experts dealing with this problem.
Eva Ďurovcová - Mária Mareková
The presented textbook is intended for students of general medicine and should support their knowledge about indication and interpretation of basic biochemical tests. Clinical biochemistry continues to be one of the most rapidly advancing areas of laboratory medicine, which in line with using of modern technology more and more emphasizes the evidence-based medicine in order to improve diagnosis and monitoring of patients. Selected topics have an ambition to outline and explain the most common issues of biochemical diagnosis of in internal medicine. Individual chapters are devoted to disorders of water, electrolyte and acid-base balance, kidney and liver disease, diabetes mellitus, and biomarkers used in the diagnosis of cardiac necrosis and heart failure. Given the limited range, the textbook merely summarizes the basic knowledge that students have obtained during the study of other subjects, such as medical biochemistry, pathophysiology and internal medicine, and emphasis is given to laboratory diagnosis in accordance with the newer guidelines of professional societies. We hope that the textbook will be helpful in the study of clinical subjects and encourage students' interest in laboratory medicine.
Authors
Slovenčina
