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Colorectal carcinoma is the most common malignant tumor of the digestive system, and its rising incidence in Slovakia—particularly among the male population—is alarming. Although significant progress has been made in the diagnosis, screening, and treatment of patients with advanced colorectal cancer, therapeutic options remain limited, necessitating the discovery of additional markers to serve as prognostic predictors.
This monograph aims to draw the attention of the professional community to the critical role and significance of the TGF-β signaling pathway in the initiation, progression, and treatment of colorectal carcinoma. A substantial portion of the text focuses on lesser-known emerging trends and ongoing clinical trials for colorectal cancer patients.
The monograph aspires to provide a balanced resource that serves as an engaging informational tool not only for specialist physicians but also for medical faculty students. By integrating novel insights and clinical data, it seeks to bridge gaps in current understanding and highlight potential avenues for future research and therapy.
Data sheet
Gabriela Štefková - Mária Zamboriová - Mária Sováriová Soósová - Renáta Shafout
We would like to introduce the study material/textbook Nursing Care Clinical Procedures I, which was developed to cover the curriculum of Nursing Care 1 for medical students. Clinical procedures are an essential component of nursing practice. The textbook contains four main chapters. Each chapter begins with a general explanation of the topic, followed by detailed method description of procedures to help students deliver high - quality care to patients. Some chapters also include appendi xes in order to pick up some special examples from clinical practice. The textbook strongly describes bandages because a carelessly or improperly applied bandage can cause discomfort to the patient, in many cases it may expose the wound to the danger of infection. To the best of wound knowledge, these procedures reflect currently accepted clinical practice and up-to-date information. The textbook can be easily integrated into an educational programme and can be used in the laboratory as well as in clinical practice. During the preparation of this textbook the information, facts, notes, publications, books and literature presented in the references section were also used. The publication include DVD, which is concentrated on applying bandages from head to lower extremity. DVD was developed in cooperation during IRES project. The student can also find additional information to study by following references. The reading level of Nursing Care Clinical Procedures I is designed to be comprehensible to as many students as possible, including those for whom Engl ish is a second language. We hope that this textbook will be useful to all readers. The authors take no personal responsibility for applying this information to a particular clinical practice
situation.
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Jana Raková - Mária Sováriová Soósová (eds.)
The profession of nursing and the development of the field of nursing care are influenced by international, societal, political, social, and cultural conditions. The result of the long-term evolution of nursing is today's network of universities and higher education institutions that prepare qualified nurses capable of providing high-quality nursing care. Healthcare professionals are trained to meet the new demands imposed by contemporary society and the labor market. Nurses are at the center of most healthcare teams, playing a key role in promoting and protecting health as well as providing nursing care across primary, secondary, and tertiary sectors.
The presented scientific anthology includes contributions of both professional and scientific nature from domestic and international authors (from the Czech Republic, Poland, and Lithuania), addressing current requirements for the development of the nursing profession. The central theme focuses on legislative changes concerning the nursing profession in Slovakia as well as in an international context. The connection between theory and practice encompasses topics related to community care, specifics of patient care, and the safety of both patients and healthcare workers.
Marek Stupák et al.
Medical Chemistry presents an overview of the most important topics of general, organic and bioinorganic chemistry for students of General and Dental Medicine study programs. Its aim is to provide a theoretical basis for the study of the subject Medical Chemistry and for understanding processes and chemical reactions which are taking place in the human body.
Each topic directly links chemical principles to the processes in living organisms and thus can help the students to clearly see the application of the presented information. Therefore, it also provides a good starting point for further study of Medical Biochemistry, for which the knowledge of these principles is necessary.
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Mária Mareková - Marek Stupák - Peter Urban - Jana Mašlanková -
Beáta Hupková - Miroslava Rabajdová
Publikácia je určená záujemcom o štúdium na UPJŠ v Košiciach, Lekárskej fakulte v odbore všeobecné lekárstvo a zubné lekárstvo. Obsahuje 1500 modelových otázok z chémie, ktoré sú spracované v súlade so vzdelávacím programom na gymnáziách a ktoré tvoria podklady písomných testov na prijímacích skúškach. Otázky na prijímacích skúškach však nemusia presne kopírovať otázky v tejto publikácii. Odpovede na otázky sú riešené formou ponúkaných variantných odpovedí obsahujúcich správne aj nesprávne možností, pričom správne odpovede sú uvedené v kľúči na konci publikácie. Táto publikácia vám poskytne možnosť overiť si hĺbku a rozsah vašich vedomostí z chémie, ktoré ste nadobudli počas stredoškolského štúdia a zároveň vám uľahčí prípravu na úspešné absolvovanie prijímacej skúšky. Autori problematiku rozdelili do kapitol, čo vám umožní rýchlo sa zorientovať a zistiť, ktorej oblasti sa musíte v štúdiu viac venovať. Cieľom predkladanej publikácie je umožniť každému uchádzačovi, ktorý má o štúdium na lekárskej fakulte vážny záujem, dobre sa pripraviť na prijímacie konanie a v prípade prijatia, mať dobrý základ na štúdium daného odboru.
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Jaroslav Majerník - Andrea Kačmariková
The university textbook "Databases in MS Access - accompanying texts for practical exercises" is intended for students of medical faculties, students of non-technical universities and all beginners in working with databases. It introduces the reader to the issue of database data processing and explains the basic principles that need to be known when creating relational databases. It is therefore suitable for those who have not yet worked with databases, or who have started thinking about managing their data using their own database.
However, even more "experienced" computer users can find useful information here. The university textbook is written in the way that its content can be mastered with basic knowledge of working with computers and programs running in the environment of MS Windows operating system.
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Terézia Kisková - Stanislav Matéffy - Františka Horváthová
The laboratory rat (Rattus norvegicus) is one of the most commonly used experimental animals. It serves as a model organism for analyzing numerous biological processes and pathological mechanisms, such as cardiovascular diseases, metabolic disorders (e.g., lipid metabolism, diabetes mellitus), neurological and neuropsychiatric conditions (e.g., stroke, epilepsy, or Alzheimer's disease), neurobehavioral research, autoimmune diseases (e.g., arthritis), cancer, and renal diseases. It offers many unique advantages for modeling human diseases, testing drugs and natural substances, and studying responses to environmental factors. The size of the laboratory rat, compared to the mouse, creates ideal conditions for physiological manipulations. Additionally, rats are used in clinical toxicology to test chemical substances (Hedrich, 2000).
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The script deals with the issue of harmful alcohol use and its consequences on individuals’ cognitive abilities. The first part is devoted to the diagnosis of dependence syndrome and the assessment of risky drinking according to internationally recognized classifications (ICD, DSM). The following chapters explain the concept of cognition and its main components. Attention is also given to changes in cognitive functions during long-term alcohol abuse. The reader is introduced to the anatomical changes in the brain caused by alcohol. Damage to white matter and disorders of neurotransmission are described. Special focus is placed on diagnoses associated with alcohol use, such as Korsakoff syndrome, Wernicke’s encephalopathy, demyelinating disorders, and hepatic encephalopathy. Attention is also paid to the possibilities of diagnosing cognitive dysfunction. General screening tests such as MMSE or MoCA are presented. More specific tools, such as PHES or BEARNI, are described in greater detail. The script also points out the possibilities of pharmacological treatment. Non-pharmacological approaches, including cognitive remediation therapy and computer-based training, are also discussed. The conclusion is devoted to modern neuromodulation methods, in particular transcranial magnetic stimulation and transcranial direct current stimulation. This university textbook is primarily intended for students of medicine, psychology, and related health sciences.
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Zuzana Dankulincová, Daniela Husárová
In the context of the deteriorating state of adolescent mental health, it is extremely important to optimize the existing mental health care system in Slovakia. There is still little comprehensive and coherent information about the functioning of the system and the process of providing assistance within professional care, its shortcomings or suggestions for improvement. This is not possible without a deep knowledge of the perspective and experiences of adolescents with mental problems themselves. The aim of this publication is therefore to present adolescents' views on the professional assistance provided as a result of experienced mental problems within the existing care system in Slovakia.
The findings from a qualitative study that focused on the views of young people themselves are presented. The chapters of the monograph capture their views on the perception of mental health problems in society, their experiences with identifying emerging problems and seeking professional help, and their experiences with the care process itself and its forms. They also capture their overall experience with both care and care providers, as well as with leaving care and its impacts in various areas. Finally, a view is presented of possible recommendations that could improve the mental health care provided from the adolescents' perspective.
This publication is intended primarily for all professionals working with adolescents with mental health problems in all branches of care, teachers and other educational staff who are in contact with them every day at school, and last but not least, all competent policy makers who care about the mental health of adolescents and have the power to improve the care provided to them.
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Behavior, in the slovak language expressed as an intention, belongs to basic mental processes of every individual. In this work I consider it as the basic component of an individual having two sides, outer- and inner side. I present it in the scheme No. 2.
The problem of behavior can not be fully covered, although there is a lot of writing, discussing and experimenting by ancient time.
The work may offer only few comments, approaching maily disorders of behavior. I present the original explanation of these disorders, dividing them on primary and derived ones. Primary disorders create the core of the disorder, derived disorders create a component of other disorders.
My classification of primary disorders is as follows:
The work is addresses to everone who is interested in his/her owm behavior, but especially for the Medical faculty and psychiatrists, for students of all our faculties.
Author
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A uterine scar is currently a significant medical problem. Uterine scars most commonly occur after a Cesarean section, which is one of the most frequent laparotomic surgeries (Yazicioglu et al., 2006). The frequency of Cesarean sections increased between 1990 and 2014 in the USA from 21.2% to 32.2% (Hamilton et al., 2015), in Great Britain from 12% to 26.2% (NHS Maternity Statistics - England, 2013-14: Summary Report, 2015), and in the Slovak Republic from 8.7% to 31% (Národné centrum zdravotníckych informácii, 2016).
After a Cesarean section (CS), there is a risk of abnormal healing of the uterotomic wound, which can result in the development of certain pathological conditions in consecutive pregnancies (uterine rupture, ectopic pregnancy in the Cesarean scar, placental disorders) (Seow et al., 2004; Oyelese and Smulian, 2006; Fitzpatrick et al., 2012). In addition, a defect in the Cesarean scar is associated with chronic dysmenorrhea, chronic pelvic pain, infertility, and postmenstrual spotting (Wang et al., 2009; Bij de Vaate et al., 2011).
Ultrasound is a valuable examination method in the diagnostic and therapeutic management of these pathological conditions.
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František Sabola kol.
Although we are not really sure if “Love is coming from the Heart” and nor we know where “the Residence of Soul” is, we are still overwhelmed by its unprecedented effort to keep us alive. Our lives are nowadays fulfilled with enormous chances to satisfy our needs and wishes. Hand in hand is changing our way of life, the intake of calories is growing and the amount of physical activity decreasing. We live longer and maybe happier but our hearts
and vessels are like mirrors showing us how we live. Diseases of the Heart and vessels have become the number one cause of death in highly developed countries including our homeland.
Prevention of cardiovascular diseases has become and an important social and health care system issue. The knowledge requirement of basic principles of cardiology and heart surgery is increasing. Without an understanding of basic principles a good clinical practice is hardly possible.
Together with my Colleagues of Heart surgery department of VÚSCH and LF UPJŠ we prepared this short overview of basic knowledge about surgery of the human heart. We hope that reading it will be more an adventure than a painful journey. If you find some answers to your unanswered questions our effort was not a waste of time.
Authors
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A.A. Ahmetova - A.A. Seidakhmetova - N.D. Kalmenov et al.
Improving the best practices in the provision of the first pre-medical care is one of the priority areas of clinical medicine in most countries of the world. Despite the success in improving the provision of medical care at the level of FPMA and emergency medical care, it is the provision of skilled care at the earliest stages of the disease or emergency conditions that determines the quality of all medical care and the future of the patient.
When rendering emergency care to the sick and injured, the time factor is very important, it prevents irreversible disturbances in the body and creates a good help for the complete cure of the patient. Textbook is designed to improve awareness of the importance of pre-medical aid to non-medical students in central Asian countries.
Mária Frankovičová - Jana Kaťuchová
Dear readers and students,
The book “Surgery for Medical Students“ is a textbook intended to be used by those studying at medical faculties and in other healthcare fields. In this textbook, the authors, encompassing all surgical specialties, have tried to provide the reader with a holistic context of the study material intended to be used in preparation for the state exam from surgery. I thank all the co-authors for their willingness and cooperation. To the students I hope you have a pleasant time reading and studying the book.
Prof. MUDr. Mária Frankovičová, PhD
E-book
Libuša Tirpáková a kol.
Primary care is the first level of the health system where people come with their health problems and where the health promotion and preventive care treatments and needs of the majority of the population are implemented.
The university textbook, which is organized in nine chapters, offers an overview of general outpatient health care from a nursing perspective. It characterizes the nursing process in ambulatory health care and models of nursing care. It addresses the implementation of advanced practice nursing in ambulatory health care and the role of the nurse in prevention and health promotion.
The textbook is intended for nursing students in both undergraduate and postgraduate education, as well as those interested in other health professions.
E-kniha
Silvia Farkašová Iannaccone a kol.
The history of ethics represents the search for a fundamental principle that would enable a person to distinguish between moral and immoral, good and evil, or right and wrong. The main issues are the motives, methods, and consequences of human actions.
The integrity of the medical profession emphasizes lifelong study and practice according to professional competence, and, last but not least, adherence to ethical principles and standards of medical ethics. Medical ethics and the related communication in the process of providing healthcare are becoming increasingly relevant topics. Communication between doctor and patient itself constitutes a very important part of the diagnostic process and treatment; it significantly contributes to the creation of a mutual relationship and, to a considerable extent, ensures patient cooperation.
The development of various information and network technologies allows for rapid communication even in medicine; however, a kind word and real contact with the patient, with an appropriate choice of verbal and nonverbal communication tools in personal contact, cannot be replaced by modern technology. The present era places demands on certain communication skills of the physician. Another ethical and legal issue is informed consent, which brings the patient’s active participation in the process of providing healthcare.
The presented publication provides basic information about medical ethics, communication in medicine in general, and communication skills in medical practice. Further chapters are devoted to the issue of informed consent, ethics, and the specifics of communication with selected groups of patients. We believe that this publication will clarify for the reader the basic ethical pillars and will be helpful for basic orientation in the issues of medical communication.
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