Nové poznatky v SMAD dependentnej dráhe transformujúceho rastového faktora u pacientov s kolorektálnym karcinómom

 Eva Mechírová -Iveta Domoráková 

Mária Mareková  et al.

Predmet Lekárska biochémia plní v medicínskom štúdiu nezastupiteľnú úlohu, naučiť študentov vnímať prirodzené, fyziologické, ako aj chorobné procesy v organizme ako deje odohrávajúce sa na molekulovej úrovni. Na rozlíšenie patologických pochodov od normálnych je potrebné zvládnuť a pochopiť zmysel obrovského množstva biochemických reakcií prebiehajúcich v bunke (bunkový metabolizmus). Osvojenie si týchto faktov je hlavným cieľom predmetu Lekárska biochémia, ktorého zvládnutie je dobrým základom pre štúdium patobiochémie, fyziológie a klinickej biochémie, ako aj mnohých ďalších odborných predmetov medicínskeho štúdia. Pre lepšie zvládnutie a pochopenie biochemických procesov sme pre študentov pripravili vysokoškolskú učebnicu „Lekárska biochémia – Semináre“, ktorá poskytuje študentom okrem teoretických úvodov aj prehľadné schémy procesov a mnoho otázok, vypracovanie ktorých by malo študentom uľahčiť prípravu na skúšku.

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Ján Kučera - Eva Kovaľová - Juraj Strecha

Peri-implantation diseases such as peri-implantitis and mucositis have a wide range of prevalence. Several etiological factors and the interaction of risk factors influence their onset and development. Careful investigation determines the diagnosis and subsequent treatment. Treatment, depending on the condition, is either non-surgical or surgical. Systematic postoperative care, a recall system, and patient instruction and cooperation are essential, which create the preconditions for successful implant treatment.

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Ingrid Hodorová - Květuše Lovásová

The publication is a continuation of the already published university textbook"Ultrasound Anatomy 1" and fills the gap in the medical literary market concerning the ultrasound view of peripheral nerves and vessels of the limbs, and neck as well.

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Marianna Vitková

Current classification of demyelinating diseases of the central nervous system according to van der Knaap and Valko from 2005 includes 97 congenital and acquired diseases that cause demyelination of the white matter of the brain and spinal cord. Most of these disorders lacks any definitive diagnostic test, so the accurate diagnosis depends on upon clinical symptoms, course of the disease, neurological findings, and the results of neuroimaging and laboratory examinations.

The aim of this textbook is to provide an accurate overview of acquired demyelinating diseases of the CNS, their etiopathogenesis, clinical picture and diagnostic options.

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Andrea Madarasová Gecková - Daniela Husárová   a kol.

Národná správa o zdraví a so zdravím súvisiacom správaní 11-, 13-, a 15-ročných školákov na základe prieskumu uskutočneného v roku 2021/2022 v rámci medzinárodného projektu „Health Behaviour in School-aged Children“ (HBSC)

Štúdia nám už niekoľko rokov poskytuje kľúčové poznatky k lepšiemu pochopeniu správania našich mladých ľudí v súvislosti so zdravím. Skúma množstvo tém súvisiacich so zdravím, ako je spánok, duševná pohoda, nutričné správanie či fyzická aktivita. Dôležitou oblasťou skúmania je aj škola a sociálne vzťahy v nej, rodina a rodinné zázemie, či vzťahy s rovesníkmi.

Zistenia prehlbujú porozumenie mechanizmom ovplyvňujúcim rozdiely a zmeny v zdraví a rizikovom správaní mladých ľudí a sú kľúčom k tvorbe efektívnych programov podpory zdravia a so zdravím súvisiaceho správania, vzdelávacích programov v tejto oblasti, k sledovaniu ich účinnosti, a to nielen na národnej, ale i na medzinárodnej úrovni. Zistené poznatky sú dôležité pre lepšie pochopenie potrieb školákov a prispôsobenie služieb a systémovej podpory tak, aby boli tieto potreby v čo najvyššej možnej miere zohľadňované v súčasnom rýchlo meniacom sa svete.

Štúdia nám môže napomôcť porozumieť vplyvom pandémie COVID-19 na kvalitu duševného i fyzického zdravia. Pandémia a s ňou súvisiace epidemiologické a hygienické opatrenia za účelom obmedzenia šírenia vírusu znamenali významné obmedzenia v každodennom živote ľudí vo všetkých vekových kategóriách – vrátane detí a adolescentov. Štandardný výchovno-vzdelávací proces, sociálny kontakt s rovesníkmi, krúžková činnosť a ďalšie záujmové aktivity v škole i mimo nej boli výrazne narušené, čo výrazne ovplyvnilo prežívanie školákov.

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Erik Dosedla

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Tatiana Muchová

Medicína stále napreduje, je stále vo vývoji. Rádiologické zobrazovacie metódy prežívajú stále výrazný rozvoj vďaka prístrojovej technike, ktorá umožňuje zavádzať nové diagnostické metódy, ako sú USG vyšetrenia s kontrastnou látkou, špeciálne CT vyšetrenia, ku ktorým je potrebný viacradový CT prístroj – CT angiografia, CT enteroklýza, CT irigografia, CT virtuálna kolonoskopia. Magnetická rezonancia už v dnešnej dobe nie je nedostupné vyšetrenie, predstavuje výrazný pokrok v diagnostike.

Vďaka moderným prístrojom môžeme vykonávať rôzne intervenčné diagnostické aj terapeutické výkony, ako sú biopsie, drenáže...

Tieto učebné texty sú určené študentom lekárskych fakúlt, obsahuje základné poznatky z rádiológie.

Publikácia je rozdelená na všeobecnú a špeciálnu časť s následným delením podľa jednotlivých modalít a vyšetrovaných orgánov.

Rádiológia predstavuje prácu s obrazovou dokumentáciou, preto aj táto publikácia je obohatená veľkým počtom obrázkov z jednotlivých rádiologických vyšetrovacích modalít.

 Magdaléna Hagovská 

The presented material provides a complex view on rehabilitation of patients in neurology. It is a second completely elaborated and extended edition of the original textbook –Neurology overview for physiotherapists. It contains data on etiology of neurological diseases, pathophysiology, examination in physiotherapy and the possibilities of a conservative treatment. From special treatment methods the faciooral therapy, acral coactivation therapy are described in greater details and the possibilities of diagnosis and training of cognitive functions. In annexes standardized questionnaire methods are described, which can be used in degree (final) works. A part of the publication is the Chapter on vertebrogenic syndromes which are frequently observed in neurological disorders. 

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Lucia Dimunová, Jana Michalková, Gabriela Štefková, Mária Zamboriová

Following innovative trends in university education, this academic textbook offers guidance to update and make the educational process more attractive for all healthcare professions. It applies critical thinking and strategic method of concept mapping in teaching, which are suitable tools for the facilitator and the educant to achieve the desired goal. Critical thinking is an essential academic skill upon which other knowledge and intellectual virtues can be built. It is also an essential equipment for every graduate of the healthcare profession. The textbook is complemented by a chapter focusing on methods for structural and formative assessment of learning outcomes. The publication is also enriched with sample digital concept maps of which cognitive content can be edited and graphically modified. The aim of this academic textbook is to present a way of acquiring knowledge through critical thinking using concept mapping as a method, with the final goal of implementing the acquired knowledge into everyday practice.

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Tatiana Muchová

Tieto učebné texty sú určené študentom lekárskych fakúlt, obsahuje základné poznatky z rádiológie.

Rádiologické zobrazovacie metódy prežívajú stále výrazný rozvoj vďaka prístrojovej technike, ktorá umožňuje zavádzať nové diagnostické metódy, ako sú USG vyšetrenia s kontrastnou látkou, špeciálne CT vyšetrenia...

Vďaka moderným prístrojom môžeme vykonávať rôzne intervenčné diagnostické aj terapeutické výkony, ako sú biopsie, drenáže...

Publikácia je rozdelená na všeobecnú a špeciálnu časť s následným delením podľa jednotlivých modalít a vyšetrovaných orgánov. 

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Lucia Bosáková - Zuzana Dankulincová - Daniela Fiľakovská

Publication called Scientific communication and management of research projects serves as background and teaching material. Its aim is to help university students and researchers develop competencies important for scientific work, such as scientific integrity, critical work with literary sources, management of research projects and scientific communication. Publication is divided into four parts. The first part is focused on the preparation of a research project, where it is important to know the basic ethical principles applied in the research project, but also to be able to critically assess literary sources and process them. In the second part, it provides information on the preparation of research projects and their management, including their financing, from preparation and planning, through initialization to implementation, management, logistics, monitoring, evaluation and termination. The third part pays attention to the preparation, processing and presentation of scientific results in the form of a scientific article, presentation, poster or press release, thus covering not only a professional but also a lay audience. The final fourth part provides information about communication with a scientific journal, whether it is the process of sending, revising an article up to its publication, or the process of assessing scientific work by scientific journal editors in the process of screening and peer review.

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Ján Varga

The cancer is the second most common reason of the death in human population. lt is responsible for approximately 10 million of death every year. Oncogynecology represents · one of the most pr ogressive part of gynecology. The interest is focused on vulvar cancer, vaginal cancer, cervical cancer, uterine cancer, fallopian tube carcinoma, ovarian cancer as well as breast cancer. Due to the range of the issue there are own workplaces ta king care just for the patients with oncogyneco logical diseases. The knowledge from oncogynecology are inevitably needed to pass the state exam as well as specialization from Gynecology and obstetrics. The presented publication is focused to mentioned oncogynecological diseases. The anatomy and histology of the vulva, vagína, cervix, uterus, fallop ian tube and ovary are described in detail. Every described carcinoma contains part about etiopathogenesis, clinical presentation, diagnostic, classification and therapy. The paper contains information suitable for students of medical faculties as well as young doctors before specialization.

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Darina Kluchová a kol. 

At present, there is a wide range of anatomy textbooks for medical students but at the same time there is an absence of anatomy books suitable for dental students. This book was designed as a base for study of trunk and limbs for dental students which should gain a sense of anatomy structures, but they do not need know details from these regions.

The amount of information in the book was extensively discussed with colleagues from clinical departments and with anatomy specialists from Slovakia and from abroad as well. Because of serious diversity of opinions we took into consideration also opinions of our specialists from dental medicine. Final material is considered to be a key information required for future dental doctors.

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Vladimíra Tomečková

Nature, as well as the human body, contains an abundant quantity of organic molecules. This textbook describes selected oxygen, sulfur, nitrogen derivatives of hydrocarbons, heterocyclic compounds of their reactions, which are important in the human body or are found in pharmaceutical active substances, poisons, foodstuffs and heat-treated food. The last part of the textbook describes the isomerism of organic compounds, which enables dynamic changes in the structure of molecules that have different properties. Nature is filled with different plants and animals and is the first laboratory to produce bioactive organic natural compounds. These compounds are compatible with human cells and are applicable as therapeutic medicine. There is an effort to reproduce natural molecules in chemical laboratories, but they cannot be as perfect as the natural ones. Synthetic molecules can serve as a model for multiple studies, but there still does not exist a magic panacea pill or a perfect copy of nature, for the treatment of various diseases. Knowledge about the regenerative and toxic effect of medicinal substances in dependence on their structure (type and number of substituents) is very important for the understanding of their role in modulation of health and disease in dependence on their concentration. Compounds can be used daily only in recommended doses (higher doses can be toxic), but still will not replace a healthy diet. People need a varied diet to be healthy, in which are all necessary nutrients, what Hippocrates demonstrated long ago “Let food be the medicine, and let medicine be the food.” This book is written for students who select bioorganic chemistry subject during the study of general medicine or dentistry as well as for motivated students who would like to practice their knowledge and wish to improve in this subject and for students who would like to learn simplified basic organic reactions with their future application in biochemistry. Learn the simple models mainly through creative simple instruction by using different colours, by repetition, practice by drawing of formulas by hand (at least three times) and memorization of common names of compounds and their reactions which have application in biochemistry. Thus, establishing simple educational methods how to distinguish organic molecules according to the colours of a functional group can promote universal learning for all students who thought that chemistry is a difficult subject, but hopefully they change their opinion after study of this book.

Keywords: organic molecules, oxygen, sulfur, nitrogen derivatives of hydrocarbons, heterocyclic compounds, chemical reactions, isomerism of organic compounds

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Mária Sováriová Soósová, Renáta Suchanová, Libuša Tirpáková

Predkladaná vysokoškolská učebnica prináša poznatky z oblasti ošetrovateľskej starostlivosti u pacientov s ochoreniami srdcovo-cievneho systému. Je určená pre poslucháčov odboru ošetrovateľstvo v rámci pregraduálneho a postgraduálneho vzdelávania, sestrám pracujúcim v tejto oblasti, ako aj ďalším odborníkom z nelekárskych vedných disciplín, ktorí sa zaoberajú starostlivosťou o pacientov s kardio-vaskulárnymi chorobami.

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