Nové poznatky v SMAD dependentnej dráhe transformujúceho rastového faktora u pacientov s kolorektálnym karcinómom

Alžbeta Blichárová - Ľudmila Verbóová - Zuzana Benetinová - Vladimír Tancoš  - Patrícia Kollárová  - Adam Nedoroščík - Erika Štammová  - Pavel Kočan

“Pathology Part 2 (summer semester) - Practical lessons for students of dental medicine” represents the second half of the university textbook designed for the pregradual study of pathology. The textbook complements the lectures of pathology and serves as a source of information for students of dental medicine, that are preparing for the practical credit, as well as the final oral examination.

In this part of the “Pathology” series, forty-four selected histopathological slides are presented. Each selected slide is provided with general information in relation to etiology and pathogenesis of the disease, as well as with corresponding morphological features, including the gross appearance and the most important histopathological characteristics. The textbook summarizes the basic concepts of systemic pathology (pathology of the heart, vessels, lungs, gastrointestinal, urogenital system, breast, musculoskeletal, nervous system, skin and infancy) and pathology of the orofacial region, that is logical continuation and completion of general pathology in the first semester.

E-book

Tatiana Kimáková

The scientific monograph focuses on health determinants, healthy nutrition, its fundamental components, the consequences of unhealthy nutrition, and alternative dietary trends. The work also includes research targeting selected lifestyle factors among university students, particularly nutrition, eating habits, and physical activity.

This scientific monograph is suitable for the scientific community, students of medical and natural sciences, and public health professionals at all three levels of higher education. It is equally valuable for members of the informed general public interested in the subject.

Download the e-book for free (pdf)

Tatiana Kimáková

Táto vedecká monografia je komplexnou vedeckou prácou zameranou na prítomnosť a pôsobenie ortuti v životnom prostredí, ale aj na rizikové faktory zdravia, ktoré sú s ňou spojené. Monografia predstavuje charakteristiku ortuti v multidisciplinárnom zábere, prezentuje využitie v priemysle a v zdravotníctve, popisuje negatívne vplyvy ortuti v životnom prostredí, na zdravotný stav obyvateľstva. Zároveň prináša návrhy a odporúčania pre rizikové skupiny ľudí. Súčasťou monografie je komplexný výskum koncentrácie ortuti vo vzorkách komodít domácej i zahraničnej produkcie a vo vzorkách rastlín pomocou atómového absorpčného spektrometra AMA 254. Vedecká monografia je vhodná pre vedeckú komunitu, študentov medicínskych, veterinárnych, prírodovedných a poľnohospodárskych odborov ako aj pre študentov verejného zdravotníctva všetkých troch stupňov vysokoškolského štúdia. Monografia je učená aj pre všetkých záujemcov z radov informovanej verejnosti.

Autorka

E-book

Martina Šemeláková (ed.)

Proceedings contain abstracts from participants of the scientific conference with international participation under the name: Student scientific international conference GenICa”, supported by the project "Bilateral relations and common knowledge between Slovakia and Iceland research at Universities on the topic "Genomic instability and cancer "GenICa", funded under the EEA and Norwegian 2014-2021 Financial Mechanism Programme (FBR02, bilateral initiatives under the Fund for Bilateral Relations at national level co-financed by EEA and Norwegian Financial Mechanism 2014-2021) which took place on 19 - 21 June 2024 in the premises of Hotel Sorea Trigan, Štrbské Pleso, Slovakia.

Download e-book for free (pdf)

E-book

Eva Ďurovcová - Mária Mareková

Clinical Biochemistry - selected chapters - MEFANET >>> 

After 7 years, we finally reworked the textbook on the subject of clinical biochemistry at UPJŠ FM in Košice. We have innovated information in accordance with recommendations of professional medical societies and added new chapters. As the scope of the subject is limited, the textbook does not cover all issues of biochemical diagnostics. It focuses on disorders of water-ion and acid-base balance disorders, and basic laboratory diagnostics of diseases of selected organs.

The textbook of clinical biochemistry has the ambition to become a practical aid for senior medical students and beginning doctors in the study of laboratory medicine. It should make it easier for them to orientate themselves in routinely used clinical-biochemical examinations and could form a springboard for a more detailed studying of laboratory methods and their use in diagnostic and monitoring algorithms.
Like any medical discipline, clinical biochemistry is evolving rapidly and gradually integrating with other areas of laboratory medicine. New diagnostic methods penetrate deeper into the essence of the biochemical mechanisms of the human body, and "omic" methods are gaining ground. It is almost sure that in a few years, laboratory examination looks quite different from today. If this publication quite hypothetically reaches its next edition, many chapters will need to updated, and new chapters written following the up-to-date status.
Authors thanks to their colleagues and reviewers for their professional comments and constructive criticism of the text - prof. Jaroslav Racek, MD, DrSc. from FM UK in Pilsen.
Authors thanks very kindly too prof. MUDr. Dušan Dobrota, CSc. (JFM UK Martin) and doc. MVDr. Zuzana Kostecká, PhD. (UVMP, Košice), who read and wrote review of this textbook.

Download the e-book for free (pdf)

Marek Šoltés - Jozef Radoňak

Laparoskopická chirurgia dnes predstavuje štandardnú a v mnohých ohľadoch preferovanú modalitu chirurgickej liečby. Dynamika jej celosvetového rozšírenia, umožnená pokrokom v biomedicínskych technológiách a rozvojom globálnych informačných a komunikačných kanálov, nemá v histórii chirurgie obdobu. V súčasnosti už prakticky neexistuje žiadna brušná operácia, ktorá by sa nevykonávala laparoskopickým spôsobom, pričom v mnohých prípadoch je už laparoskopický postup metódou voľby.

Napriek, a možno práve vďaka bezprecedentne rýchlej penetrácii laparoskopických operácií do každodennej chirurgickej praxe naďalej v mnohých ohľadoch absentujú všeobecne akceptované technické štandardy. Vysoká variabilita procesných postupov v rámci jednotlivých laparoskopických operácií vychádza skôr zo zvyklostí daného pracoviska ako z medicíny založenej na dôkazoch. Táto situácia je ďalej modifi kovaná rozvojom nových a staronových koncepcií charakteru minilaparoskopie, SILS či NOTES a ich hybridných kombinácií s klasickou laparoskopiou.

Cieľom monografi e je pritiahnuť pozornosť odbornej verejnosti späť k základným princípom laparoskopickej chirurgie, ktoré by mali byť základňou pre efektívne a bezpečné vykonávanie laparoskopických operácií, ako aj bázou pre kritický postoj k módnym inovatívnym trendom. Obsahovo sa sústredí skôr na všeobecne menej známe a v našich podmienkach zriedkavo diskutované témy, ktorých význam sa hlbšie analyzoval len v nedávnej minulosti. Našou ambíciou bolo vytvoriť vyvážený materiál, ktorý by bol zaujímavým primárnym informačným zdrojom nielen pre lekárov špecialistov, ale aj pre poslucháčov lekárskych fakúlt a kolegov v špecializačnej príprave v chirurgických odboroch.

Autori

E-book

Tomáš Toporcer - Adrián Kolesár

The textbook "Heart surgery for medics" was created in response to repeated requests from students of the Faculty of Medicine P.J.Šafárik University, for the surgery state exam study material. In terms of content, the text corresponds to the required knowledges in cardiac surgery, needed to pass the state exam in surgery. Orientation in the issue of cardiac surgery is not only necessary for students whose specialization will be closely related to the given field. Basic knowledge of cardiac surgery is necessary for every medical faculty graduate. Knowing the treatment options, but also the possible complications of individual cardiac surgical procedures, is necessary for most medical specialties. Only by mastering the basics of each medical field can the patient be properly, adequately and modernly managed.

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Peter Berek 

S vývojom endovaskulárnej chirurgie dochádza postupne k rozvoju stentingu ACI. Minimálne invazívny prístup spravil túto metodiku vhodnú pre pacientov s vážnymi konkomitatnými kardiálnymi alebo pľúcnymi ochoreniami. Ďalšou výhodou v porovnaní s chirurgickou liečbou bol lepší prístup k ACI u pacientov po rádioterapii, po predchádzajúcich operáciách na krku, ale aj u pacientov so stenózami blízko lebečnej bázy. Porovnanie CEA vs CAS je zaujímavou a diskutabilnou témou mnohých štúdií. Avšak, aj napriek celosvetovému mohutnému rozvoju endovaskulárnej liečby karotická endarterektómia ostáva zlatým štandardom liečby stenózy ACI u symptomatických aj asymptomatických pacientov.

V tejto monografii by sme radi akcentovali a systematizovali problematiku chirurgickej prevencie CMP z pohľadu cievneho chirurga.

H.Mičková - V.Habalová - J.Židzik - E.Slabá

E-book

Peter Lengyel - Eugen Frišman (eds.)

Zborník abstraktov

TÉMY KONGRESU

Lekárska sekcia
• Chirurgická liečba popálenín
• Popáleniny elektrickým prúdom
• Termické úrazy u detí
• Vojenské termické úrazy
• Varia
• Posterová sekcia

Sekcia zdravotných sestier
• Starostlivosť o detského pacienta s termickým úrazom
• Starostlivosť dospelých pacientov s rozsiahlymi popáleninami
• Význam práce sestier na operačných sálach
• Liečba pacientov v hyperbarickej komore

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 Ingrid Dravecká 

College textbook "Investigation methods in Diabetology" is designed for students of medicine. It can help them in preparing for an exam from internal medicine but specially in preparing for a state exam from internal medicine. The introduction is devoted to classification and diagnostic criteria of diabetes mellitus. Further It describes investigation options (clinical, laboratory, imaging) of different types of diabetes mellitus as well as its acute and chronic complications. At the end there are given diagnostics and classification of the individual components of the metabolic syndrome, obesity and dyslipidemia.

Author

Mária Pallayová - Štefan Kujaník

The “Textbook of Practical Physiology, Part I - Cardiovascular Physiology” by Mária Pallayová and Štefan Kujaník is a practical textbook of Human Physiology intended for English speaking medical students from general medicine and dentistry curricula.

The textbook covers basic principles in cardiovascular physiology and methods of the cardiovascular examination. Adequate knowledge of the cardiovascular physiology is important for the understanding of cardiovascular system function, as well as for the diagnosis and proper treatment of cardiovascular and other diseases. The practical tasks are constructed to facilitate knowledge acquisition and encourage students to develop practical skills, for instance the ability to follow experimental protocols, to work as part of a team, and to interpret data.

The textbook is written in English and comprises 91 pages in B5 format, grouped into twelve chapters. Each chapter is divided into six sections (Introduction, Principle, Importance, Materials, Procedure, and Protocol) to facilitate students’ understanding of the topics and assist them with preparation of the laboratory reports. The text is accompanied by explanatory figures, graphs, and tables that contribute to the learning experience.

Authors

Miroslav Gajdoš - Vladimír Kaťuch

  „Neurochirurgia pre študentov medicíny“ je určená pre študentov lekárskych fakúlt. Základné informácie o neurochirurgii získajú aj študenti príbuzných odborov /zubné lekárstvo/, ale aj absolventi lekárskych fakúlt v začiatkoch svojej klinickej praxe.

Učebný text je rozdelený do desiatich kapitol. Tie sa ďalej delia na podkapitoly.

Prvá kapitola je zameraná na dejiny chirurgie, následne na dejiny neurochirurgie. V tejto kapitole autor pripomína, že operované lebky patria k najstarším dôkazom operačnej činnosti našich predkov. 

Druhá a tretia kapitola  je venovaná diagnostike a základným operačným výkonom.

Pre pochopenie patologicko-fyziologických dejov je potrebné pozorne preštudovať štvrtú kapitolu, v ktorej autor popisuje základné patologické mechanizmy, ktoré pôsobia na povrchu ale aj v hĺbke mozgových tkanív.

Piata kapitola je venovaná závažnej problematike  -  vrodeným chybám mozgu, miechy a ich podporných štruktúr.

Nie menej závažnou problematikou pre neurochirurgov sú nádory CNS,  periférnych nervov, lebky a chrbtice. Tie sú popísané v šiestej kapitole.                 

V siedmej kapitole sú popísané cievne ochorenia CNS: autor popisuje aneuryzmy mozgových ciev, ich diagnostiku a liečbu, ďalej cievne malformácie mozgu, artériovenózne malformácie mozgu a v neposlednom rade spinálne artériovenózne malformácie.

8. kapitola je čo do obsahu najrozsiahlejšia. Prináša informácie o poranení pacientov pri úraze. O ich závažnosti, diagnostike a možnej liečbe – konzervatívnej a chirurgickej.

9. kapitola je venovaná nie menej závažnej problematike, a to degeneratívnym ochoreniam chrbtice.

V 10. kapitole sa autor venuje najnovším metódam liečby chronickej bolesti a epileptochirurgii.

E-book

Pavol Jarčuška - Daniel Pella - Ján Rosocha (eds.)

Proceedings of lectures from thematic conferences organized by UVP MediPark

UVP Medipark – the path to innovation in research, diagnostics, and treatment – was the title of the conference held on Tuesday, May 29, 2018, at the premises of the Faculty of Medicine, Pavol Jozef Šafárik University in Košice. The patronage of the event was taken over by the rector of UPJŠ, Prof. RNDr. Pavol Sovák, CSc. The conference program was divided into two main areas – Innovative scientific technologies, clinical research, and the path to the development of new drugs, and UVP Medipark – main research areas.

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Andrea Madarasová Gecková - Daniela Husárová a kol.

The aim of this publication is to present the latest findings of the international study Health Behavior in School-aged Children (HBSC), regarding the health and health-related behavior of school-aged children in Slovakia.After four years, it again brings information on various topics covering physical and mental health, nutritional behavior, leisure-time activities, use of psychoactive substances, within social environment of school-aged children, including family, school and peers. The publication also presents newfindings connected to objectively measured physical fitness of these children. Finally, data about school-aged children with special educational needs are also presented.The findings play an important role in understanding the needs of the new generation of adolescents and are an important source of information for all those who work with them, not only professionals but also parents.Last but not least, they are also beneficial for all stakeholders and institutions who participate in the preparing of policies and strategies focused on supporting the health of school-aged children.

Mária Mareková a kol. 

Medical biochemistry is integral parts of basic theoretic knowledge of contemporary graduate at medical faculties. This textbook intends to help the undergraduate students of study branches General Medicine and Dental Medicine for the course of “Medical Biochemistry”. It is structured into 10 chapters concerning several topics: enzymology, cells membrane, metabolism, biochemistry of blood and organs, as well as some parts of clinical biochemistry.

The theoretical knowledge of this subject, which student obtains in the lectures, is verified in laboratory practices and is expanded in seminaries. Our selection of topics makes the text especially appropriate for medical students and managing of problems gives the students satisfactory ground for effective study of medical biochemistry and other related study subjects (e.g. clinical biochemistry, physiology, pathophysiology) in the sense of comprehension of relative continuity and interdependence of biochemical process or their function respectively.

Since the textbook brings only the skeleton survey on the biochemical problematic concerning medicine, students should broaden presented facts by additional study from lectures and/or from other sources. We expect this study literature to serve as a basic study material for mentioned medical study branches for preparation to written part of exam from “Medical Biochemistry”.

Authors

Alžbeta Blichárová - Ľudmila Verbóová - Zuzana Benetinová - Vladimír Tancoš  - Patrícia Kollárová  - Adam Nedoroščík - Erika Štammová  - Pavel Kočan

“Pathology Part 2 (summer semester) - Practical lessons for students of dental medicine” represents the second half of the university textbook designed for the pregradual study of pathology. The textbook complements the lectures of pathology and serves as a source of information for students of dental medicine, that are preparing for the practical credit, as well as the final oral examination.

In this part of the “Pathology” series, forty-four selected histopathological slides are presented. Each selected slide is provided with general information in relation to etiology and pathogenesis of the disease, as well as with corresponding morphological features, including the gross appearance and the most important histopathological characteristics. The textbook summarizes the basic concepts of systemic pathology (pathology of the heart, vessels, lungs, gastrointestinal, urogenital system, breast, musculoskeletal, nervous system, skin and infancy) and pathology of the orofacial region, that is logical continuation and completion of general pathology in the first semester.

E-book

Tatiana Kimáková

The scientific monograph focuses on health determinants, healthy nutrition, its fundamental components, the consequences of unhealthy nutrition, and alternative dietary trends. The work also includes research targeting selected lifestyle factors among university students, particularly nutrition, eating habits, and physical activity.

This scientific monograph is suitable for the scientific community, students of medical and natural sciences, and public health professionals at all three levels of higher education. It is equally valuable for members of the informed general public interested in the subject.

Download the e-book for free (pdf)

Tatiana Kimáková

Táto vedecká monografia je komplexnou vedeckou prácou zameranou na prítomnosť a pôsobenie ortuti v životnom prostredí, ale aj na rizikové faktory zdravia, ktoré sú s ňou spojené. Monografia predstavuje charakteristiku ortuti v multidisciplinárnom zábere, prezentuje využitie v priemysle a v zdravotníctve, popisuje negatívne vplyvy ortuti v životnom prostredí, na zdravotný stav obyvateľstva. Zároveň prináša návrhy a odporúčania pre rizikové skupiny ľudí. Súčasťou monografie je komplexný výskum koncentrácie ortuti vo vzorkách komodít domácej i zahraničnej produkcie a vo vzorkách rastlín pomocou atómového absorpčného spektrometra AMA 254. Vedecká monografia je vhodná pre vedeckú komunitu, študentov medicínskych, veterinárnych, prírodovedných a poľnohospodárskych odborov ako aj pre študentov verejného zdravotníctva všetkých troch stupňov vysokoškolského štúdia. Monografia je učená aj pre všetkých záujemcov z radov informovanej verejnosti.

Autorka

E-book

Martina Šemeláková (ed.)

Proceedings contain abstracts from participants of the scientific conference with international participation under the name: Student scientific international conference GenICa”, supported by the project "Bilateral relations and common knowledge between Slovakia and Iceland research at Universities on the topic "Genomic instability and cancer "GenICa", funded under the EEA and Norwegian 2014-2021 Financial Mechanism Programme (FBR02, bilateral initiatives under the Fund for Bilateral Relations at national level co-financed by EEA and Norwegian Financial Mechanism 2014-2021) which took place on 19 - 21 June 2024 in the premises of Hotel Sorea Trigan, Štrbské Pleso, Slovakia.

Download e-book for free (pdf)

E-book

Eva Ďurovcová - Mária Mareková

Clinical Biochemistry - selected chapters - MEFANET >>> 

After 7 years, we finally reworked the textbook on the subject of clinical biochemistry at UPJŠ FM in Košice. We have innovated information in accordance with recommendations of professional medical societies and added new chapters. As the scope of the subject is limited, the textbook does not cover all issues of biochemical diagnostics. It focuses on disorders of water-ion and acid-base balance disorders, and basic laboratory diagnostics of diseases of selected organs.

The textbook of clinical biochemistry has the ambition to become a practical aid for senior medical students and beginning doctors in the study of laboratory medicine. It should make it easier for them to orientate themselves in routinely used clinical-biochemical examinations and could form a springboard for a more detailed studying of laboratory methods and their use in diagnostic and monitoring algorithms.
Like any medical discipline, clinical biochemistry is evolving rapidly and gradually integrating with other areas of laboratory medicine. New diagnostic methods penetrate deeper into the essence of the biochemical mechanisms of the human body, and "omic" methods are gaining ground. It is almost sure that in a few years, laboratory examination looks quite different from today. If this publication quite hypothetically reaches its next edition, many chapters will need to updated, and new chapters written following the up-to-date status.
Authors thanks to their colleagues and reviewers for their professional comments and constructive criticism of the text - prof. Jaroslav Racek, MD, DrSc. from FM UK in Pilsen.
Authors thanks very kindly too prof. MUDr. Dušan Dobrota, CSc. (JFM UK Martin) and doc. MVDr. Zuzana Kostecká, PhD. (UVMP, Košice), who read and wrote review of this textbook.

Download the e-book for free (pdf)