Nové poznatky v SMAD dependentnej dráhe transformujúceho rastového faktora u pacientov s kolorektálnym karcinómom

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Erik Dosedla

A uterine scar is currently a significant medical problem. Uterine scars most commonly occur after a Cesarean section, which is one of the most frequent laparotomic surgeries (Yazicioglu et al., 2006). The frequency of Cesarean sections increased between 1990 and 2014 in the USA from 21.2% to 32.2% (Hamilton et al., 2015), in Great Britain from 12% to 26.2% (NHS Maternity Statistics - England, 2013-14: Summary Report, 2015), and in the Slovak Republic from 8.7% to 31% (Národné centrum zdravotníckych informácii, 2016).

After a Cesarean section (CS), there is a risk of abnormal healing of the uterotomic wound, which can result in the development of certain pathological conditions in consecutive pregnancies (uterine rupture, ectopic pregnancy in the Cesarean scar, placental disorders) (Seow et al., 2004; Oyelese and Smulian, 2006; Fitzpatrick et al., 2012). In addition, a defect in the Cesarean scar is associated with chronic dysmenorrhea, chronic pelvic pain, infertility, and postmenstrual spotting (Wang et al., 2009; Bij de Vaate et al., 2011).

Ultrasound is a valuable examination method in the diagnostic and therapeutic management of these pathological conditions.

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Ingrid Hodorová - Květuše Lovásová

The publication is a continuation of the already published university textbook"Ultrasound Anatomy 1" and fills the gap in the medical literary market concerning the ultrasound view of peripheral nerves and vessels of the limbs, and neck as well.

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Ján Kučera - Eva Kovaľová - Juraj Strecha

Peri-implantation diseases such as peri-implantitis and mucositis have a wide range of prevalence. Several etiological factors and the interaction of risk factors influence their onset and development. Careful investigation determines the diagnosis and subsequent treatment. Treatment, depending on the condition, is either non-surgical or surgical. Systematic postoperative care, a recall system, and patient instruction and cooperation are essential, which create the preconditions for successful implant treatment.

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Marianna Vitková

Current classification of demyelinating diseases of the central nervous system according to van der Knaap and Valko from 2005 includes 97 congenital and acquired diseases that cause demyelination of the white matter of the brain and spinal cord. Most of these disorders lacks any definitive diagnostic test, so the accurate diagnosis depends on upon clinical symptoms, course of the disease, neurological findings, and the results of neuroimaging and laboratory examinations.

The aim of this textbook is to provide an accurate overview of acquired demyelinating diseases of the CNS, their etiopathogenesis, clinical picture and diagnostic options.

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