27.KOŠICKÝ MORFOLOGICKÝ DEŇ: Miesto morfológie v súčasnej medicíne

Helena Mičková -  Jozef Židzik -  Mária Mareková - Marek Stupák - 

Peter Urban

Modelové otázky na prijímacie skúšky pre bakalárske štúdium sú určené záujemcom o bakalárske študijné programy na Univerzite Pavla Jozefa Šafárika v Košiciach, Lekárskej fakulte. Publikácia obsahuje 500 otázok z biológie a 500 otázok z chémie, ktoré tvoria podklady písomných testov na prijímacie skúšky. Otázky na prijímacích skúškach však nemusia presne kopírovať modelové otázky. Testy z chémie a biológie pokrývajú tie okruhy učiva z predmetov biológia a chémia na slovenských gymnáziách, vedomosti z ktorých sú vyžadované od poslucháčov bakalárskych študijných smerov (napr. ošetrovateľstvo, fyzioterapia, verejné zdravotníctvo). Otázky z biológie a z chémie sú predkladané v dvoch samostatných celkoch. Odpovede na otázky sú riešené formou ponúkaných variantných odpovedí, obsahujúcich správne aj nesprávne možnosti. Správne odpovede sú vyznačené v kľúči na konci publikácie.

Príklady z chémie tvoria zvláštnu časť, v ktorej nie sú ponúkané variantné odpovede. Pre lepšiu kontrolu správnosti výpočtu je v zátvorke uvedený jeden správny výsledok (z viacerých možných – líšiacich sa napr. v jednotkách – gramy, miligramy, móly). Autori publikácie sa snažili minimalizovať možné chyby v texte a vyhnúť sa nejednoznačným formuláciám otázok a odpovedí. Modelové otázky sú okrem prípravy na prijímacie skúšky na UPJŠ LF v Košiciach vhodné aj na zopakovanie gymnaziálneho učiva z biológie a chémie pred maturitnou skúškou.

E-book

Jana Mašlanková

Colorectal carcinoma is the most common malignant tumor of the digestive system, and its rising incidence in Slovakia—particularly among the male population—is alarming. Although significant progress has been made in the diagnosis, screening, and treatment of patients with advanced colorectal cancer, therapeutic options remain limited, necessitating the discovery of additional markers to serve as prognostic predictors.

This monograph aims to draw the attention of the professional community to the critical role and significance of the TGF-β signaling pathway in the initiation, progression, and treatment of colorectal carcinoma. A substantial portion of the text focuses on lesser-known emerging trends and ongoing clinical trials for colorectal cancer patients.

The monograph aspires to provide a balanced resource that serves as an engaging informational tool not only for specialist physicians but also for medical faculty students. By integrating novel insights and clinical data, it seeks to bridge gaps in current understanding and highlight potential avenues for future research and therapy.

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Erik Dosedla

A uterine scar is currently a significant medical problem. Uterine scars most commonly occur after a Cesarean section, which is one of the most frequent laparotomic surgeries (Yazicioglu et al., 2006). The frequency of Cesarean sections increased between 1990 and 2014 in the USA from 21.2% to 32.2% (Hamilton et al., 2015), in Great Britain from 12% to 26.2% (NHS Maternity Statistics - England, 2013-14: Summary Report, 2015), and in the Slovak Republic from 8.7% to 31% (Národné centrum zdravotníckych informácii, 2016).

After a Cesarean section (CS), there is a risk of abnormal healing of the uterotomic wound, which can result in the development of certain pathological conditions in consecutive pregnancies (uterine rupture, ectopic pregnancy in the Cesarean scar, placental disorders) (Seow et al., 2004; Oyelese and Smulian, 2006; Fitzpatrick et al., 2012). In addition, a defect in the Cesarean scar is associated with chronic dysmenorrhea, chronic pelvic pain, infertility, and postmenstrual spotting (Wang et al., 2009; Bij de Vaate et al., 2011).

Ultrasound is a valuable examination method in the diagnostic and therapeutic management of these pathological conditions.

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Iveta Domoráková - Štefan Tóth - Zuzana Fagová - Eva Mechírová - Alexandra Kunová - Kristína Čurgali - Viera Eliášová - Monika Holodová - Marianna Danková

In our new electronic textbook, FUNDAMENTALS OF HISTOLOGY II – Textbook and Atlas of Microscopic Anatomy of Organs, we present students and the professional public with essential information about the microscopic structure of organs, accompanied by extensive visual documentation of organ structures and clear legends for the microphotographs.

All histological specimens come from the archive of the Institute of Histology and Embryology, are used in practical exercises, and are also included in teaching presentations. The electronic textbook is intended for undergraduate and postgraduate students of general medicine and dentistry at medical faculties, as well as for students of veterinary medicine and pharmacy, and biology students at faculties of natural sciences.

The textbook is designed so that students can find clear explanations of most medical terms and also reinforce their knowledge of professional terminology in Latin. An advantage of the electronic textbook is the ability to enlarge microscopic photographs, allowing detailed observation of structures without any qualitative loss of the viewed image. The microphotographs used in the atlas were taken with the following equipment: Zeiss Promicra and Olympus BX50 with a Canon EOS 2000D digital camera and QP Industrial 3.2 software.

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Miriam Kozárová

The publication "News in Diabetology and Lipidology" focuses on extremely relevant topics in diabetology and lipidology, reflecting the state of these issues in light of the recommendations from professional societies from 2019. In diabetology, it primarily addresses the intensification of antidiabetic treatment using modern drug classes—specifically, incretin enhancers and sodium-glucose cotransporter-2 (SGLT-2) inhibitors (gliflozins). Few medical fields have experienced such a development of new pharmacological options as diabetology has in the last two decades. While pharmacotherapy for type 2 diabetes (DM2) was limited to the use of biguanides, sulfonylurea derivatives, and insulin throughout the second half of the last century, recent years have introduced entirely new groups of oral antidiabetics with cardio- and nephroprotective effects. In lipidology, it pertains to the new recommendations from the European Atherosclerosis Society (EAS) with new treatment goals for serum lipids and lipoproteins, including the use of biological therapies.

This textbook is primarily intended for medical students in doctoral studies and doctoral candidates, as well as for physicians preparing for specialization exams in internal medicine, endocrinology, diabetology, metabolic disorders and nutrition, as well as cardiology and angiology. I believe that readers will find information in this publication that will aid them in their studies and translate into their daily clinical practice.

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Magdaléna Hagovská - Alena Buková - Ľubomír Lachváč

Overweight as a risk factor for the development of civilization diseases and urogenital dysfunctions

Overweight and obesity represent a significant risk factor for the development of several diseases of civilisation, such as cardiovascular disease, type 2 diabetes mellitus and various forms of cancer. They also contribute significantly to urogenital dysfunctions such as urinary incontinence, overactive bladder and pelvic organ prolapse. Mechanisms that link excess weight to these dysfunctions include increased intra-abdominal pressure, hormonal changes, and chronic inflammatory processes that negatively affect the structure and function of the urogenital system. Prevention and treatment of overweight and obesity are therefore crucial not only in terms of reducing the risk of civilization diseases, but also in improving the quality of life through the prevention and treatment of urogenital dysfunctions.

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 Miroslav Mydlík - Július Vajó (eds.) 

Miroslav Gajdoš - Igor J.Šulla a kol. 

Učebnica pre lekárov a študentov všeobecného lekárstva

Medicína je neprestajne sa vyvíjajúca vedná disciplína. Základný výskum v spojení s klinickou praxou rozširujú súčasné vedomosti, čo sa veľmi výrazne prejavuje aj v neurovedách, v praktickej podobe hlavne v neurofyziológii, neurofarmakológii, neurológii, diagnostickej aj intervenčnej neurorádiológii a v neurochirurgii. V priebehu ostatných troch desaťročí neurovedy prekonali pozoruhodný vývoj. Podnietili ho potreby praxe a umožnilo využitie poznatkov biológie, chémie, biochémie, aplikovanej matematiky, výpočtovej techniky a fyzikálnych objavov realizovaných v moderných prístrojoch i liečebných postupoch. To všetko podstatne uľahčilo, spresnilo a urýchlilo diagnostiku ochorení nervového systému, umožnilo relatívne bezpečné chirurgické zásahy na štruktúrach v minulosti nedostupných a otvorilo nové perspektívy, hlavne v oblasti reparácie poškodených tkanív, respektíve ich funkcií autotransplantáciou kmeňových/progenitorových buniek, terapeutickými zásahmi na genómovej, prípadne proteómovej úrovni. Ako vysokoškolskí učitelia sa každodenne stretávame nielen s mimoriadnym záujmom študentov i zdravotníckych pracovníkov o nové poznatky, ale aj s určitou neistotou pri posudzovaní možností, ktoré jednotlivé disciplíny patriace do skupiny neurovied ponúkajú. Jednou z príčin spomenutého javu je pravdepodobne časový faktor, keď najnovšie poznatky ešte nestačili preniknúť do odbornej literatúry, alebo v nej nie sú dostatočne zdôraznené. Druhou príčinou môže byť pomerne malá skúsenosť s niektorými ochoreniami nervového systému, ktoré sa síce vyskytujú zriedkavejšie, ale ich následky sú závažné. Cieľ, ktorý sme sledovali napísaním tejto učebnice, bolo aspoň čiastočne odstrániť spomenuté nedostatky všetkých odborných publikácií.

Počas prípravy rukopisu sme sa snažili, aby terapeutické postupy, názvy liekov a ich dávkovanie boli v súlade s najnovšími poznatkami vedy a klinickej praxe. Oprávnene však môžeme predpokladať, že budúce objavy zmenia súčasný pohľad na problematiku diagnostiky aj liečby ochorení nervového systému.

Vysokoškolská učebnica je určená študentom všeobecného lekárstva UPJŠ Lekárskej fakulty v Košiciach a lekárom, zameraným hlavne na všeobecné lekárstvo.

Kolektív autorov

E-kniha

Silvia Farkašová Iannaccone a kol.

The history of ethics represents the search for a fundamental principle that would enable a person to distinguish between moral and immoral, good and evil, or right and wrong. The main issues are the motives, methods, and consequences of human actions.

The integrity of the medical profession emphasizes lifelong study and practice according to professional competence, and, last but not least, adherence to ethical principles and standards of medical ethics. Medical ethics and the related communication in the process of providing healthcare are becoming increasingly relevant topics. Communication between doctor and patient itself constitutes a very important part of the diagnostic process and treatment; it significantly contributes to the creation of a mutual relationship and, to a considerable extent, ensures patient cooperation.

The development of various information and network technologies allows for rapid communication even in medicine; however, a kind word and real contact with the patient, with an appropriate choice of verbal and nonverbal communication tools in personal contact, cannot be replaced by modern technology. The present era places demands on certain communication skills of the physician. Another ethical and legal issue is informed consent, which brings the patient’s active participation in the process of providing healthcare.

The presented publication provides basic information about medical ethics, communication in medicine in general, and communication skills in medical practice. Further chapters are devoted to the issue of informed consent, ethics, and the specifics of communication with selected groups of patients. We believe that this publication will clarify for the reader the basic ethical pillars and will be helpful for basic orientation in the issues of medical communication.

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E-publication

Eva Slabá-Helena Mičková- Terézia Hudáková-Janka Vašková

Teaching texts „Praktické cvičenia z lekárskej biológie“ provide the theoretical foundations of microscopy, various microscopic techniques and preparation of microscopic slides in an understandable form. The chapters of the teaching texts contain model questions and tasks from cytology, molecular biology and genetics enabling students to acquire new knowledge from individual thematic areas and provide instructions for the implementation of tasks during laboratory lessons in medical biology. Teaching texts are primarily intended for the practical lessons in the subjects Biológia 1 and Biológia 2 for Slovak students of the first year of General Medicine and the subjects Lekárska biológia and Genetika a regeneratívna medicína for Slovak students of the first and second year of Dental Medicine at P. J. Šafárik University in Košice – Faculty of Medicine.

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Darina Kluchová a kol. 

An illustrated text for dental students

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Ladislav Kočan - Dušan Rybár - Róbert Rapčan

The autonomic nervous system is a vital component of the peripheral nervous system, responsible for maintaining homeostasis and regulating internal processes within the body. Unlike the voluntary control exerted by the central nervous system, the autonomic nervous system operates involuntarily, innervating smooth organs, vessels, skin glands, and even exerting some influence over skeletal muscles in connection with vegetative functions such as breathing, digestion, and the urinary and gonadal systems. Its impact extends crucially to the cardiac muscles of the heart and plays a significant role in endocrine and metabolic functions, thermoregulation, as well as emotional and behavioral responses, including adaptive reactions to stressors.

The aim of this publication is to provide a comprehensive and objective exploration of the anatomical and physiological intricacies of the autonomic nervous system, offering insights into its clinical applications. Within these pages, we meticulously delineate various interventional therapeutic procedures tailored to specific diagnoses related to the autonomic nervous system, aligning each intervention with the anatomical framework of the autonomic system. The efficacy of these procedures is evaluated based on the level of evidence, as per the current recommendations of Evidence-Based Medicine.

This publication is primarily crafted for fifth and sixth-year medical students and medical professionals specializing in anesthesiology, intensive care, and pain medicine. It serves as a valuable resource for gaining a deeper understanding of autonomic nervous system function and its clinical implications, facilitating informed decision-making in clinical practice.

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Ivana Skoumalová - Zuzana Dankulincová

The publication entitled Competencies for clinical practice in the field of communication with the patient serves as the background and teaching material.

The text is structured to bring theoretical knowledge about the topic, current research findings in the field and practical tips for training skills in practice. It provides clear information on individual parts of the training and is designed to acquire knowledge that is the basis for practical skills in medical communication, especially in communication with patients.

It is intended for general and dental students to deepen their knowledge and acquire missing skills in medical communication, which are evidence-based and research-validated skills that have a demonstrable positive impact on patient communication.

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Silvia Timková - Marcel Riznič - Jozef Minčík 

 Eugen Ďurovič - Peter Kizek

Vysokoškolský učebný text Ochorenia jazyka sa zameriava na anomálie a choroby postihujúce jazyk.  V jednotlivých kapitolách opisuje vrodené stavy, s ktorými sa na jazyku stretávame, ich diagnostiku ako aj možnosti liečby, ako aj jednotlivé samostatné chorobné jednotky. Úvodnú kapitolu tvoria lokálne ochorenia jazyka, kedy ochorenie nemá prejavy na iných ústnych slizniciach. Ďalšou skupinou sú ochorenia, kde je symptomatológia choroby prítomná na jazyku, ale aj na ostatných ústnych slizniciach. Okrem týchto stavov vznikajúcich priamo v ústnej dutine sú v ďalších kapitolách rozobraté stavy, kde celkové ochorenia, akými sú infekčné, endokrinologické, krvné a dermatologické ochorenia vyvolávajú zmeny na jazyku. Samostatné kapitoly sú venované prekanceróznym stavom a benígnym a tumoriformným léziam.  Poslednú kapitolu tvoria ochorenia jazyka u detskej populácie.

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Mária Sováriová Soósová, Renáta Suchanová, Libuša Tirpáková

Predkladaná vysokoškolská učebnica prináša poznatky z oblasti ošetrovateľskej starostlivosti u pacientov s ochoreniami srdcovo-cievneho systému. Je určená pre poslucháčov odboru ošetrovateľstvo v rámci pregraduálneho a postgraduálneho vzdelávania, sestrám pracujúcim v tejto oblasti, ako aj ďalším odborníkom z nelekárskych vedných disciplín, ktorí sa zaoberajú starostlivosťou o pacientov s kardio-vaskulárnymi chorobami.

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