Liekové formy a aplikačné cesty podávania liekov so zameraním na ich význam v humánnej medicíne

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Mária Sováriová Soósová, Renáta Suchanová, Libuša Tirpáková

Predkladaná vysokoškolská učebnica prináša poznatky z oblasti ošetrovateľskej starostlivosti u pacientov s ochoreniami srdcovo-cievneho systému. Je určená pre poslucháčov odboru ošetrovateľstvo v rámci pregraduálneho a postgraduálneho vzdelávania, sestrám pracujúcim v tejto oblasti, ako aj ďalším odborníkom z nelekárskych vedných disciplín, ktorí sa zaoberajú starostlivosťou o pacientov s kardio-vaskulárnymi chorobami.

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Denisa Harvanová (ed.)

The proceedings contain abstracts submitted by participants of the international scientific event entitled "MVDr. Ján Rosocha, CSc. Memorial" (3rd year). The event is part of a bilateral project named: "Extracellular vesicles: a promising cell-free therapy for cartilage repair (SK-AT-23-0005)", which is implemented within the framework of cooperation between Pavol Jozef Šafárik University in Košice, Slovakia, and the University for Continuing Education Krems in Austria. It is funded by the Slovak Research and Development Agency (APVV) under the bilateral call Slovakia-Austria 2023 and by OEAD – Agency for Education and Internationalisation under the project number SK11/2024. The MVDr. Ján Rosocha, CSc. Memorial (3rd year) was held on October 14, 2025, on the premises of the Faculty of Medicine, P. J. Šafárik University in Košice, Slovak Republic.

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Silvia Danková - Lucia Dimunová - Beáta Grešš Halász - Jana Sušinková

The present multimedia university textbook is intended for students of the bachelor's degree programme in nursing, not excluding both medical and nursing degree courses.

The purpose of the present publication is to provide a comprehensive view of the nature of surgical nursing, focusing on the method of providing nursing care - the nursing process. It comprehensively describes the individual steps of perioperative nursing care and the subsequent possible complications associated with surgical procedures. Documents the depth of knowledge and skills training in chronic wound care management issues. Respects the culture of patient and healthcare professional safety.

The college textbook uses e-learning methods in combination with traditional face-to-face education. Based on the latest resources, it respects the concept of health care delivery and professional training of nurses.

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Janette Baloghová

Všeobecná dermatovenerológia je nosnou časťou dermatovenerológie. Morfológia, popis a charakteristika jednotlivých eflorescencií sú kľúčové v diagnostike a diferenciácii kožných ochorení spolu s dobre odobratou anamnézou. Snahou bolo vytvoriť vysokoškolský učebný text, ktorý tvorí praktický návod ako vyšetrovať pacienta s kožným ochorením. Cieľom jednotlivých kapitol je dokonale si osvojiť dermatologickú terminológiu, fyzikálnym vyšetrením vnímať špeciálne kožné znaky a zmeny, vedieť sa orientovať v algoritme pomocných vyšetrovacích metód a testov a pochopiť rozdielne vlastnosti a charakteristiku kože vzhľadom na vek pacienta, vznik, priebeh a trvanie kožných prejavov. Posledná kapitola predstavuje praktickú topografiu kožných ochorení v tabuľkách. Dermatovenerológia patrí k interdisciplinárnym odborom, preto všeobecná dermatológia bude určite dobrým sprievodcom pri diagnostike kožných ochorení nielen študentov medicíny, ale aj lekárov prvého kontaktu a styčných odborov.

Miroslav Gajdoš - Vladimír Kaťuch

  „Neurochirurgia pre študentov medicíny“ je určená pre študentov lekárskych fakúlt. Základné informácie o neurochirurgii získajú aj študenti príbuzných odborov /zubné lekárstvo/, ale aj absolventi lekárskych fakúlt v začiatkoch svojej klinickej praxe.

Učebný text je rozdelený do desiatich kapitol. Tie sa ďalej delia na podkapitoly.

Prvá kapitola je zameraná na dejiny chirurgie, následne na dejiny neurochirurgie. V tejto kapitole autor pripomína, že operované lebky patria k najstarším dôkazom operačnej činnosti našich predkov. 

Druhá a tretia kapitola  je venovaná diagnostike a základným operačným výkonom.

Pre pochopenie patologicko-fyziologických dejov je potrebné pozorne preštudovať štvrtú kapitolu, v ktorej autor popisuje základné patologické mechanizmy, ktoré pôsobia na povrchu ale aj v hĺbke mozgových tkanív.

Piata kapitola je venovaná závažnej problematike  -  vrodeným chybám mozgu, miechy a ich podporných štruktúr.

Nie menej závažnou problematikou pre neurochirurgov sú nádory CNS,  periférnych nervov, lebky a chrbtice. Tie sú popísané v šiestej kapitole.                 

V siedmej kapitole sú popísané cievne ochorenia CNS: autor popisuje aneuryzmy mozgových ciev, ich diagnostiku a liečbu, ďalej cievne malformácie mozgu, artériovenózne malformácie mozgu a v neposlednom rade spinálne artériovenózne malformácie.

8. kapitola je čo do obsahu najrozsiahlejšia. Prináša informácie o poranení pacientov pri úraze. O ich závažnosti, diagnostike a možnej liečbe – konzervatívnej a chirurgickej.

9. kapitola je venovaná nie menej závažnej problematike, a to degeneratívnym ochoreniam chrbtice.

V 10. kapitole sa autor venuje najnovším metódam liečby chronickej bolesti a epileptochirurgii.

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Mária Rašiová

Cardiovascular diseases are among the main causes of morbidity and mortality in developed countries. Academic textbook: Selected Chapters from Angiology is devoted to the most common vascular diseases that the angiologist encounters on a daily basis.

Dilated artery diseases (abdominal aortic aneurysm), as well as stenotizing diseases of peripheral arteries, are described. Diseases such as deep vein thrombosis, thrombophlebitis and chronic venous insufficiency are discussed in the venous vascular system section. I also deal with the most common lymphatic vascular system disease ˗ lymphoedema.

In the individual chapters the risk factors of the diseases, symptoms and signs, diagnostics, treatment modalities (pharmacological therapy, endovascular therapy, angiosurgical therapy) and possible complications of the therapy are briefly analyzed.

My priority was to present the information in a logical, interesting and comprehensible form for students and for common clinical practice.

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Štefan Tóth

Dyslipidemia is one of the main risk factors for the development of cardiovascular diseases. In recent years, extensive research has been conducted, leading to changes in therapeutic recommendations for dyslipidemia. These scripts aim to provide readers in the introductory chapters with information on the basic management of patients with dyslipidemia, procedures, target levels, and available medications and their combinations for achieving target levels, focusing on the practical aspect of dyslipidemia treatment. In the special section of the script, an overview is provided of the basic characteristics, studies of individual available hypolipemics, as well as hypolipemics that are not yet on our market or are still in the stage of clinical trials

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Martina Chylová - Lívia Peštová

Učebné texty Psychológia v medicíne prezentujú základné poznatky o správaní sa a prežívaní človeka nielen v chorobe, približujú psychodiagnostické postupy a psychoterapeutickú liečbu pacientov. Podstatnou súčasťou práce je kapitola, ktorá pojednáva o lekárskej psychológii. Táto časť práce poukazuje na význam komunikácie a interakcie medzi lekárom a pacientom a nutnosť zohľadnenia významných vzťahových aspektov medzi nimi. Kapitola sa ďalej venuje psychosomatickému rozmeru vybraných chorôb v kontexte rôznych medicínskych odborov. Zároveň je analyzovaná psychologická problematika pacientov s telesným, zmyslovým postihnutím a duševne zaostalých osôb, záver učebnice predstavuje opis špecifík práce s detským pacientom. Pomocou týchto učebných textov si študenti medicíny majú osvojiť základné psychologické poznatky, získať vedomosti o efektívnej komunikácii s pacientmi, príbuznými a ostatným zdravotníckym personálom, tvorivo pristupovať k riešeniu problémov pri práci. Zároveň práca zdôrazňuje potrebu duševnej hygieny a starostlivosti o seba, ktorá je v práci lekára nevyhnutná.

Marek Stupák et al.

Medical Chemistry presents an overview of the most important topics of general, organic and bioinorganic chemistry for students of General and Dental Medicine study programs. Its aim is to provide a theoretical basis for the study of the subject Medical Chemistry and for understanding processes and chemical reactions which are taking place in the human body.

Each topic directly links chemical principles to the processes in living organisms and thus can help the students to clearly see the application of the presented information. Therefore, it also provides a good starting point for further study of Medical Biochemistry, for which the knowledge of these principles is necessary.

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Rastislav Dudič

Vysokoškolská učebnica je svojim rozsahom, obsahom, formou a spôsobom spracovania určená pre študentov bakalárskeho študijného programu Fyzioterapia. Je zameraná na získanie základných vedomostí z oblasti gynekológie a pôrodníctva.

Učebnica pozostáva z dvoch hlavných kapitol: vybrané kapitoly z gynekológie a vybrané kapitoly z pôrodníctva. Prvá kapitola je členená na 6 podkapitol. Autor v nich uvádza anatómiu ženských genitálií, základy gynekologického vyšetrenia, zápaly ženských pohlavných orgánov a sexuálne prenosné ochorenia. Záver prvej kapitoly je venovaný benígnym a malígnym nádorovým ochoreniam ženských genitálií. Druhá kapitola je členená tiež na 6 podkapitol, v ktorých autor sa venuje prenatálnej starostlivosti, uloženiu plodu v maternici, pôrodu, pridruženým ochoreniam v tehotenstve a potratom.

Učebnica je napísaná v rozsahu 83 strán. Uvedený text obsahuje 35 obrázkov, 9 tabuliek, zoznam skratiek a značiek a zoznam použitej literatúry. Autor cituje 35 prevažne zahraničných citácií.

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Terézia Kisková - Stanislav Matéffy - Františka Horváthová

The laboratory rat (Rattus norvegicus) is one of the most commonly used experimental animals. It serves as a model organism for analyzing numerous biological processes and pathological mechanisms, such as cardiovascular diseases, metabolic disorders (e.g., lipid metabolism, diabetes mellitus), neurological and neuropsychiatric conditions (e.g., stroke, epilepsy, or Alzheimer's disease), neurobehavioral research, autoimmune diseases (e.g., arthritis), cancer, and renal diseases. It offers many unique advantages for modeling human diseases, testing drugs and natural substances, and studying responses to environmental factors. The size of the laboratory rat, compared to the mouse, creates ideal conditions for physiological manipulations. Additionally, rats are used in clinical toxicology to test chemical substances (Hedrich, 2000).

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Tatiana Kimáková

This scientific monograph is a comprehensive scientific work focused on the presence and effects of mercury in the environment, as well as the health risk factors associated with it.

The monograph presents a characterization of mercury in a multidisciplinary scope, discusses its use in industry and healthcare, and describes the negative impacts of mercury on the environment and public health. It also provides proposals and recommendations for at-risk groups. The monograph includes a comprehensive study of mercury concentration in samples of domestic and foreign production commodities and plant samples using the atomic absorption spectrometer AMA 254.

This scientific monograph is suitable for the scientific community, students of medical, veterinary, natural sciences, and agricultural fields, as well as public health students at all three levels of university study. It is also intended for all interested members of the informed public.

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Zuzana Dankulincová a kol.

The scientific monograph is the output of the Care4Youth project, which aimed to map the current system of care for adolescents with emotional and behavioral problems (EBP) in Slovakia. It captures what the care system is and what its possible shortcomings are from the perspective of all those affected (adolescents with problems, their parents, care providers and other institutions involved).

It also looks at the trajectory of adolescents with EBP in the care system, i.e. when and how adolescents with problems enter and leave the care system, or pass from one type of care to another and what impact different trajectories have on them.

Last but not least, the aim of the monograph was to provide expert information on what are the risk and protective factors that will affect their success in the care system or, conversely, that threaten them. All this in order to support the proposal for improvements in the care system that would benefit all stakeholders.

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Katarína Tokarčíková

The university textbook entitled "Vasculitis" provides a systematic overview of vasculitis encountered in clinical practice. The text is supplemented with tables reflecting the latest recommendations of professional societies and illustrations that aid in understanding the subject matter. The individual chapters analyze the etiopathogenesis of individual types of vasculitis, their epidemiology, clinical symptoms, diagnosis, differential diagnosis, treatment, prognosis and also prevention and screening options. The publication is intended for doctoral students at medical faculties, but it can also be used by doctors in specialist training in internal medicine, angiology, cardiology, rheumatology, nephrology and general medicine.

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Radoslav Morochovič - Rastislav Burda -

Ľuboš Tomčovčík - Peter Cibur - Štefan Ivanecký

Vysokoškolský učebný text určený pre študentov všeobecného lekárstva, zubného lekárstva a fyzioterapie, ktorý obsahuje podstatné časti z predmetu úrazová chirurgia potrebných na zvládnutie vysokoškolského štúdia.

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Ladislav Kočan-Dušan Rybár-Róbert Rapčan

The autonomic nervous system is a vital component of the peripheral nervous system, responsible for maintaining homeostasis and regulating internal processes within the body. Unlike the voluntary control exerted by the central nervous system, the autonomic nervous system operates involuntarily, innervating smooth organs, vessels, skin glands, and even exerting some influence over skeletal muscles in connection with vegetative functions such as breathing, digestion, and the urinary and gonadal systems. Its impact extends crucially to the cardiac muscles of the heart and plays a significant role in endocrine and metabolic functions, thermoregulation, as well as emotional and behavioral responses, including adaptive reactions to stressors. The aim of this publication is to provide a comprehensive and objective exploration of the anatomical and physiological intricacies of the autonomic nervous system, offering insights into its clinical applications. Within these pages, we meticulously delineate various interventional therapeutic procedures tailored to specific diagnoses related to the autonomic nervous system, aligning each intervention with the anatomical framework of the autonomic system. The efficacy of these procedures is evaluated based on the level of evidence, as per the current recommendations of Evidence-Based Medicine. This publication is primarily crafted for fifth and sixth-year medical students and medical professionals specializing in anesthesiology, intensive care, and pain medicine. It serves as a valuable resource for gaining a deeper understanding of autonomic nervous system function and its clinical implications, facilitating informed decision-making in clinical practice.

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