Liekové formy a aplikačné cesty podávania liekov so zameraním na ich význam v humánnej medicíne

E-book

Pavol Jarčuška - Pavol Kristian - Ivan Schréter (eds.)

The abstract almanac was issued at the occasion of XXII. Slovak – Czech congress on infectoius diseases held in Jasná.

Overall it contains 70 reports that cover current issues in infectology. Contributions are focused on patients with infections caused by multidrug resistant organisms, HIV infected patients, patients with hepatitis and infections in immunocompromised patients.

Thers is a special section dedicated to new aspects in nursing care.

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Jozef Firment a kolektív

The textbook provides a clear view of the importance of respiratory care, with an emphasis on prevention and treatment procedures. The introductory chapters present the anatomical and physiological principles of respiratory function necessary for understanding further contexts of the issue. Methods for facilitating expectoration of mucus and foreign bodies are explained. Great emphasis is placed on correct procedures for humidifying and warming the inhaled mixture, including the basics of aerosol therapy. This is an issue that is particularly important in invasive, but also non-invasive methods of ventilation therapy. The work also contains more detailed physical justifications for the explained principles. From a practical perspective, the chapters that draw attention to frequent errors in the use of humidification and aerosol technologies are also important. The texts are supplemented with many illustrative original images and explanations.

The textbook is intended primarily for doctors, nurses and physiotherapists working in the fields of anaesthesiology and intensive care, emergency medicine, in all workplaces that are dedicated to the treatment and care of patients with respiratory problems, such as pneumology, internal medicine, surgical units treating patients in the postoperative period. Last but not least, it is also an excellent supplementary study material for medical students, nursing students and paramedics.

Eva Mechírová - Iveta Domoráková

The content of this "Practical lessons" represents a record of the appearance, under the light microscope of the tissues, organs and systems of the human body. In addition, it provides visual guidelines during the practical phase of a histology course. It is hoped that this book will be especially useful to students to understand fully the microscopic structure of human tissues and organs.

Authors

E-book

Peter Berek

University scripts “Visceral pathology of vascular origin“analyze one of the most challenging vascular regions, the aorta and the visceral aortic branches, from the surgical perspective. The diagnostic and the treatment aneurysms of the abdominal aorta are dedicated to the first chapter. Early diagnostic and operative treatment is crucial in the treatment of ruptured aneurysms of the abdominal aorta. Shortening of the interval between the patient’s arrival with ruptured aneurysm of the abdominal aorta into the hospital and the beginning of the operation decreased the perioperative mortality. This shortening, together with the use of the cell savers, led to the dropping of perioperative mortality from 50% to 20%. The diagnostics and surgical treatment of the acute and chronic occlusion of the aorta and iliac arteries are analyzed in the second chapter. In this chapter, the focus is given to the aortobifemoral bypass as “the gold standard“ of the surgical therapy of aortoiliac atherosclerosis. The management of acute mesenteric ischemia is the content of the third chapter. Acute mesenteric ischemia is a severe condition with high mortality. The problem of acute mesenterial ischemia is a delayed diagnostic that is the reason for poor therapeutical outcomes of the disease. The possible imagine studies and operations used in treating acute mesenteric ischemia are brought in this chapter. Chronic mesenteric ischemia leads to cachexia. The diagnosis of chronic mesenterial ischemia is one of the most demanding, and surgical therapy used in the treatment of chronic mesenterial ischemia also belongs to the most challenging operations. Left-sided colon ischemia belongs to the severe complications of the aortoiliac reconstructions. Left-sided colon ischemia has a high mortality. In the prevention of the left-sided colon, ischemia is preserving at least one internal iliac artery. The complex diagnostics treatment of intraabdominal compressive syndromes as Dunbar syndróme, „Nutcracker“ syndróme a Wilkie syndróme, analyzed in the last chapter.

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Eva Slabá - Jozef Židzik a kolektív

Vysokoškolská učebnica „Lekárska biológia a genetika“ poskytuje v zrozumiteľnej podobe teoretické základy bunkovej biológie, molekulovej biológie a genetiky. Obsahuje najnovšie poznatky z relevantných odborov doplnené názornými obrázkami, tabuľkami a grafmi. Prehľadne členené kapitoly zoznámia študentov s problematikou bunkovej biológie, procesov molekulovej biológie a zákonitosťami genetiky. Vysokoškolská učebnica je určená predovšetkým pre slovenských študentov I. ročníka lekárskych fakúlt. Jej obsah je podkladom pre úspešné zvládnutie obsahovej náplne predmetu biológia. Učebnica je vhodná aj ako hlavný zdroj informácií pre študentov prírodovedeckých fakúlt. Okrem základných údajov obsahujú niektoré kapitoly aj doplňujúce informácie pre lepšie pochopenie jednotlivých tematických okruhov. Tieto podrobnejšie údaje sú odlíšené veľkosťou písma a nie sú nevyhnutné pre zvládnutie skúšky z biológie. Príslušné informácie však môžu využiť i študenti vyšších ročníkov lekárskych fakúlt či študenti postgraduálneho štúdia.

E-publication

Eva Slabá-Helena Mičková-Jozef Židzik-Lucia Klimčáková-Janka Vašková

Teaching texts „Practical Lessons in Medical biology“ provide the theoretical foundations of microscopy, various microscopic techniques and preparation of microscopic slides in an understandable form. The chapters of the teaching texts contain model questions and tasks from cytology, molecular biology and genetics enabling students to acquire new knowledge from individual thematic areas and provide instructions for the implementation of tasks during laboratory lessons in medical biology. Teaching texts are primarily intended for the practical lessons in the subjects Biology 1 and Biology 2 for foreign students of the first year of General Medicine and the subjects Medical Biology and Genetics and Regenerative Medicine for foreign students of the first and second year of Dental Medicine at P. J. Šafárik University in Košice – Faculty of Medicine.

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 Miroslav Mydlík - Július Vajó (eds.) 

 Helena Mičková a kol. 

František Sabola kol.

Although we are not really sure if “Love is coming from the Heart” and nor we know where “the Residence of Soul” is, we are still overwhelmed by its unprecedented effort to keep us alive. Our lives are nowadays fulfilled with enormous chances to satisfy our needs and wishes. Hand in hand is changing our way of life, the intake of calories is growing and the amount of physical activity decreasing. We live longer and maybe happier but our hearts
and vessels are like mirrors showing us how we live. Diseases of the Heart and vessels have become the number one cause of death in highly developed countries including our homeland.
Prevention of cardiovascular diseases has become and an important social and health care system issue. The knowledge requirement of basic principles of cardiology and heart surgery is increasing. Without an understanding of basic principles a good clinical practice is hardly possible.
Together with my Colleagues of Heart surgery department of VÚSCH and LF UPJŠ we prepared this short overview of basic knowledge about surgery of the human heart. We hope that reading it will be more an adventure than a painful journey. If you find some answers to your unanswered questions our effort was not a waste of time.

Authors

Jozef Kafka 

Otázky človeka, jeho bytia, násilie znepokojujú ľudí od najdávnejších čias ľudskej spoločnosti a sú nemalými problémami aj v prítomnosti. V tejto pôvodnej práci, ktorej predchádzali viaceré štúdie autora (najpodrobnejšie Kafka, 2002), sa zameriavam na opísanie násilia vo všetkých základných formách, čo je jednou z jej osobitostí. Podávam operačný výmer násilia:

Násilie je vedomá ľudská činnosť využívajúca ako prostriedok násilného činu fyzickú alebo psychickú silu na ovplyvnenie druhého človeka (pri pôsobení na seba ide o zvláštny prípad násilia), ktorý potom koná pod vplyvom tohto pôsobenia nedobrovoľne, z donútenia.

Nazdávam sa, že násilie charakterizuje určitá situácia, v ktorej sa stretávajú najmenej dvaja ľudia: aktér násilia a obeť násilia, alebo sa stretajú dvaja aktéri a jeden z nich sa zvyčajne stane obeťou. To je však osobitný prípad, ktorým sa teraz nebudem zaoberať. Ak je násilie zamerané proti vlastnej osobe, je aktér násilia súčasne aj obeťou. Aktér, ktorého osobnosť a motívy bývajú rôzne, začína násilný čin využívajúc pritom viaceré prostriedky a pôsobí nimi na druhého človeka, ktorého núti vykonávať svoju vôľu, čím sa tento stáva obeťou. Celý akt má určité následky. Napadnutý sa môže brániť tak, že násilie zvládne alebo to môže skončiť tragicky, keď násiliu podľahne. Táto relatívne jednoduchá reakcia sa stáva zložitejšou pri skupinovej forme násilia a celkom neprehľadnou pri hromadnom násilí.

Opisujem tieto základné formy násilia:

• - násilie proti vlastnej osobe vrátane samovraždy,
• - násilie individuálne, spôsobené jedným aktérom násilia,
• - násilie skupinové, charakterizované malými skupinami,
• - násilie hromadné alebo kolektívne medzi veľkými skupinami, vrátane vojen a revolúcií,
• - násilie proti neživej a živej prírode.

Práca končí krátkou analýzou liečby násilného správania a dôsledkov násilia s možnosťami jej prevencie. Opieram sa aj o vlastné skúsenosti s prejavmi násilia v psychiatrických zariadeniach. Nazdávam sa, že je to práca veľmi aktuálna, informatívna, ale aj pôvodná, lebo podáva v koncentrovanej podobe celý rozsiahly fenomén násilia s jeho základnými charakteristikami. Podobnú prácu v našej literatúre nemáme.

Autor

Michal Legiňa kol.

Progress in biology and medicine has always been significantly related to advances in physics. Not only has physics supplied instruments and methods of measurement that have led to many discoveries in physiology and medicine, but methods of physical research have changed many of the older approaches to the biologic sciences. Such circumstances have even led to development of a new scientific field: biophysics, which uses to a great extent physical instrumentation procedures applied to an experimental system. Because any instrument is an additional factor in any experimental system, it may affect the data. To interpret physical data on biological material correctly then, it is necessary to consider the characteristics of instrument response.

A practical course enables a student to acquire some skills, experience and methodological knowledge for performance of experiments and evaluation of measured data. Due to the fast development of instrumentation technology, it is not possible to teach every operation and procedure upon instruments we may use in a future. Besides the basic physical principles, the aim of a practical course is to point out some general rules and skills for instrument operation and for the interpretation of the measured values derived from such operation.

There are two kinds of lessons in practical courses. The first one focuses on laboratory measurements of some important physical quantities and the evaluation of the measured data. These measured quantities are components of the subject “medical biophysics” or of the phenomena studied. Experience provided in managing various scales and tables, as well as in the construction of tables and graphs is substantial. Lessons also enable students to repeat and to strengthen their knowledge of secondary school physics, which is useful for understanding of many phenomena studied in medical biophysics. The second kind of lesson provides experience with some of the diagnostic and therapeutic medical instruments, which can be seen in practical medicine.

The understanding of basic physical principles of corresponding instruments is both recommended and demanded. Theoretical preparation is not only an appropriate condition for the practical managing of the whole lesson, but also helps to avoid injury. This textbook, therefore, intends to help students in preparing for both the practical lessons and the final exam.

Authors

E-booka

Denisa Harvanová (ed.)

The proceedings contain abstracts submitted by participants of the international scientific event entitled "MVDr. Ján Rosocha, CSc. Memorial" (3rd year). The event is part of a bilateral project named: "Extracellular vesicles: a promising cell-free therapy for cartilage repair (SK-AT-23-0005)", which is implemented within the framework of cooperation between Pavol Jozef Šafárik University in Košice, Slovakia, and the University for Continuing Education Krems in Austria. It is funded by the Slovak Research and Development Agency (APVV) under the bilateral call Slovakia-Austria 2023 and by OEAD – Agency for Education and Internationalisation under the project number SK11/2024. The MVDr. Ján Rosocha, CSc. Memorial (3rd year) was held on October 14, 2025, on the premises of the Faculty of Medicine, P. J. Šafárik University in Košice, Slovak Republic.

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E-book

Kvetoslava Rimarová a kol.

Učebnica poskytuje komplexný a interdisciplinárny pohľad na problematiku humánnej výživy v kontexte verejného zdravotníctva, hygieny výživy a prevencie ochorení. Je koncipovaná ako základný aj rozširujúci študijný materiál pre študentov zdravotníckych, biomedicínskych a verejno-zdravotníckych odborov, ako aj pre odborníkov pôsobiacich v oblasti výživy, hygieny, potravinárstva a zdravotnej politiky. Publikácia systematicky pokrýva všetky kľúčové oblasti výživy človeka – od základných zložiek potravy (bielkoviny, sacharidy, tuky, vitamíny, minerálne látky), ich biologickej a energetickej hodnoty, cez odporúčané výživové dávky a tvorbu racionálneho jedálnička, až po hodnotenie nutričného stavu populácie. Osobitná pozornosť je venovaná antioxidantom, probiotikám a funkčným potravinám, ktoré predstavujú moderný a dynamicky sa rozvíjajúci segment výživovej vedy.

Učebnica reflektuje aktuálne trendy v stravovaní vrátane alternatívnych spôsobov výživy, prerušovaného pôstu, vysokoproteínových diét a konzumácie spracovaných a ultraprocesovaných potravín, pričom ich hodnotí z hľadiska vedeckých dôkazov, zdravotných prínosov aj rizík. Dôležitou súčasťou je problematika cudzorodých látok v potravinách, potravinárskych aditív a legislatívnych rámcov ich používania, ako aj význam pitnej vody, jej kvalita, úprava a zdravotné riziká spojené s kontamináciou. Publikácia sa venuje aj špecifickým oblastiam, ako sú alimentárne nákazy, výživa v jednotlivých vývinových obdobiach detí, nemocničné stravovanie a diétne systémy.

Praktickú hodnotu učebnice zvyšuje zaradenie metodicky spracovanej praktickej časti zameranej na mikrobiologické hodnotenie pokrmov rýchleho občerstvenia, založenej na reálnych dátach regionálnych úradov verejného zdravotníctva. Text je spracovaný prehľadne, s využitím tabuliek, obrázkov a aktuálnej odbornej literatúry, čo umožňuje čitateľovi nielen osvojenie teoretických poznatkov, ale aj ich aplikáciu v praxi. Učebnica predstavuje ucelený, moderný a vedecky podložený zdroj poznatkov o výžive ako jednom zo základných determinantov zdravia populácie.

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Alžbeta Blichárová a kolektív

“Pathology Part 1 (winter semester) - Practical lessons for students of general medicine” represents the first half of the university textbook designed for the pregradual study of pathology. The textbook complements the lectures of pathology and serves as a source of information for students of general medicine, that are preparing for the practical as well as the final oral examination.

In this part of the “Pathology” series, seventy selected histopathological slides are presented. Each selected slide is provided with general information in relation to etiology and pathogenesis of the disease, as well as with corresponding morphological features, including the gross appearance and the most important histopathological characteristics. The textbook summarizes the basic concepts of general pathology that are necessary to master the broad field of systemic pathology in the second semester.

Keywords: general pathology – histopathological slides – general medicine – gross appearance – microscopic image

 Kvetoslava Rimárová 

The theme of the presented university textbook is a summary of selected basic knowledge of hygiene - environmental medicine. The script includes significant areas of environmental medicine as a science: the basics of environmental medicine, health and prevention issues of environmental health and risk assessment of potential exposure, the issue of air pollution, indoor pollution, problems of drinking water, the action of soil and solid waste, further issue of housing, nutrition and the impact of working conditions on health. Nutritional factors textbooks dealing with issues of rational nutrition, describe the individual components of nutrition, but also address the issue of food hygiene and the possibilities of foodborne infections. One chapter is also devoted to the impact of environmental conditions on health of children and youth. 

University textbook as a manuscript consists from 199 manuscript pages, is divided into 12 basic chapters, contains 36 citations in the literature.  In the Preface, the issue of categorization of diseases and define the basic concepts of health, prevention. Other chapters deal with the above selected chapters hygiene.

This university textbook comes as a basic university textbook for students of general  medicine in the English language, for students of bachelor's and master's studies  of medical schools - mainly bachelor's and master' program of  "Public health". Students of medicine and dentistry can also use these textbooks as an educational tool in the study of other subjects in the teaching of public health.

Autor

Jozef Mihalik - Silvia Rybárová

Vysokoškolské učebné texty sú určené pre študentov 1. ročníka odboru Všeobecné lekárstvo, pričom pozostávajú zo všeobecnej a špeciálnej časti. Vo všeobecnej časti sa študenti oboznámia so základnými pitevnými nástrojmi a pracovným postupom používanými pri pitve ľudského tela. V špeciálnej časti je horná končatina opísaná podľa jednotlivých krajín. V tejto časti učebných textov sú podrobne opísané hranice jednotlivých oblastí, kožné rezy, ako aj podkožné a hĺbkové štruktúry ktoré sa tu nachádzajú.