Pathology Part 2 Practical lessons for students of general medicine

Gabriela Štefková - Mária Zamboriová - Mária Sováriová Soósová - Renáta Shafout

We would like to introduce the study material/textbook Nursing Care Clinical Procedures I, which was developed to cover the curriculum of Nursing Care 1 for medical students. Clinical procedures are an essential component of nursing practice. The textbook contains four main chapters. Each chapter begins with a general explanation of the topic, followed by detailed method description of procedures to help students deliver high - quality care to patients. Some chapters also include appendi xes in order to pick up some special examples from clinical practice. The textbook strongly describes bandages because a carelessly or improperly applied bandage can cause discomfort to the patient, in many cases it may expose the wound to the danger of infection. To the best of wound knowledge, these procedures reflect currently accepted clinical practice and up-to-date information. The textbook can be easily integrated into an educational programme and can be used in the laboratory as well as in clinical practice. During the preparation of this textbook the information, facts, notes, publications, books and literature presented in the references section were also used. The publication include DVD, which is concentrated on applying bandages from head to lower extremity. DVD was developed in cooperation during IRES project. The student can also find additional information to study by following references. The reading level of Nursing Care Clinical Procedures I is designed to be comprehensible to as many students as possible, including those for whom Engl ish is a second language. We hope that this textbook will be useful to all readers. The authors take no personal responsibility for applying this information to a particular clinical practice
situation.

 Eva Ďurovcová - Mária Mareková 

The presented textbook is intended for students of general medicine and should support their knowledge about indication and interpretation of basic biochemical tests. Clinical biochemistry continues to be one of the most rapidly advancing areas of laboratory medicine, which in line with using of modern technology more and more emphasizes the evidence-based medicine in order to improve diagnosis and monitoring of patients. Selected topics have an ambition to outline and explain the most common issues of biochemical diagnosis of in internal medicine. Individual chapters are devoted to disorders of water, electrolyte and acid-base balance, kidney and liver disease, diabetes mellitus, and biomarkers used in the diagnosis of cardiac necrosis and heart failure. Given the limited range, the textbook merely summarizes the basic knowledge that students have obtained during the study of other subjects, such as medical biochemistry, pathophysiology and internal medicine, and emphasis is given to laboratory diagnosis in accordance with the newer guidelines of professional societies. We hope that the textbook will be helpful in the study of clinical subjects and encourage students' interest in laboratory medicine.

Authors

Mária Frankovičová - Jana Kaťuchová - Jozef Radoňak a kol.

Vysokoškolská učebnica určená študentom všeobecného lekárstva, ktorá predstavuje kompaktný zdroj informácií nevyhnutných pre úspešné zvládnutie štúdia predmetu chirurgia. Obsahuje kapitoly z chirurgickej propedeutiky, chirurgie krku, hrudníka a brucha, ako aj nadstavbových chirurgických odborov, vrátane traumatológie, neurochirurgie, ortopédie, urológie, cievnej, plastickej, detskej chirurgie a kardiochirurgie.

Marek Šoltés - Jozef Radoňak

Laparoskopická chirurgia dnes predstavuje štandardnú a v mnohých ohľadoch preferovanú modalitu chirurgickej liečby. Dynamika jej celosvetového rozšírenia, umožnená pokrokom v biomedicínskych technológiách a rozvojom globálnych informačných a komunikačných kanálov, nemá v histórii chirurgie obdobu. V súčasnosti už prakticky neexistuje žiadna brušná operácia, ktorá by sa nevykonávala laparoskopickým spôsobom, pričom v mnohých prípadoch je už laparoskopický postup metódou voľby.

Napriek, a možno práve vďaka bezprecedentne rýchlej penetrácii laparoskopických operácií do každodennej chirurgickej praxe naďalej v mnohých ohľadoch absentujú všeobecne akceptované technické štandardy. Vysoká variabilita procesných postupov v rámci jednotlivých laparoskopických operácií vychádza skôr zo zvyklostí daného pracoviska ako z medicíny založenej na dôkazoch. Táto situácia je ďalej modifi kovaná rozvojom nových a staronových koncepcií charakteru minilaparoskopie, SILS či NOTES a ich hybridných kombinácií s klasickou laparoskopiou.

Cieľom monografi e je pritiahnuť pozornosť odbornej verejnosti späť k základným princípom laparoskopickej chirurgie, ktoré by mali byť základňou pre efektívne a bezpečné vykonávanie laparoskopických operácií, ako aj bázou pre kritický postoj k módnym inovatívnym trendom. Obsahovo sa sústredí skôr na všeobecne menej známe a v našich podmienkach zriedkavo diskutované témy, ktorých význam sa hlbšie analyzoval len v nedávnej minulosti. Našou ambíciou bolo vytvoriť vyvážený materiál, ktorý by bol zaujímavým primárnym informačným zdrojom nielen pre lekárov špecialistov, ale aj pre poslucháčov lekárskych fakúlt a kolegov v špecializačnej príprave v chirurgických odboroch.

Autori

Alžbeta Blichárová - Ľudmila Verbóová - Zuzana Benetinová - Vladimír Tancoš  - Patrícia Kollárová  - Adam Nedoroščík - Erika Štammová  - Pavel Kočan

„Patológia 2. časť (letný semester) - Praktické cvičenia pre študentov zubného lekárstva“ je druhou časťou vysokoškolskej učebnice predstavujúcou druhú polovicu výučby (letný semester). V tejto časti je popísaných 44 diagnóz, kde každej je venovaná jedna strana. V popise je uvedené poradové číslo zhodujúce sa s číslom preparátu a názov danej diagnózy. Študent sa pri každom preparáte oboznámi so základnými informáciami o danej chorobe, jej makroskopickým a mikroskopickým obrazom. Navyše je vytvorené miesto, v ktorom si študent môže zaznačiť (nakresliť) charakteristický obraz danej choroby. Preparáty v tejto učebnici sú zamerané na špeciálnu patológiu – patológiu srdca a ciev, pľúc, gastrointestinálneho, urogenitálneho systému, prsníka, pohybového  a nervového systému, kože a novorodeneckého veku. 20 diagnóz je venovaných iba patológii orofaciálnej oblasti.

Tým, že učebnica umožňuje preparáty zakresľovať, vytvára študentom priestor pre trvalejšie zapamätanie si danej problematiky. Je vynikajúcim zdrojom pre prípravu študentov na kolokvium a ústnu skúšku.

Alžbeta Blichárová - Ľudmila Verbóová - Zuzana Benetinová - Vladimír Tancoš  - Patrícia Kollárová  - Adam Nedoroščík - Erika Štammová  - Pavel Kočan

“Pathology Part 2 (summer semester) - Practical lessons for students of dental medicine” represents the second half of the university textbook designed for the pregradual study of pathology. The textbook complements the lectures of pathology and serves as a source of information for students of dental medicine, that are preparing for the practical credit, as well as the final oral examination.

In this part of the “Pathology” series, forty-four selected histopathological slides are presented. Each selected slide is provided with general information in relation to etiology and pathogenesis of the disease, as well as with corresponding morphological features, including the gross appearance and the most important histopathological characteristics. The textbook summarizes the basic concepts of systemic pathology (pathology of the heart, vessels, lungs, gastrointestinal, urogenital system, breast, musculoskeletal, nervous system, skin and infancy) and pathology of the orofacial region, that is logical continuation and completion of general pathology in the first semester.

Mária Mareková a kol.

Predkladaná vysokoškolská učebnica predstavuje základy biochémie a je určená predovšetkým pre bakalárske  študijné programy (napr. ošetrovateľstvo, fyzioterapia, verejné zdravotníctvo). Vysokoškolská učebnica predstavuje zjednodušenú alternatívu lekárskej biochémie a je svojím obsahom aj rozsahom vhodná pre študentov nelekárskych študijných odborov. Okrem priblíženia základných metabolických dejov prebiehajúcich v organizme človeka, ponúka aj stručný prehľad klinicko-biochemických parametrov štandardne vyšetrovaných pri podozrení na ich poruchy. Snaží sa poskytnúť študentom, predovšetkým zdravotníckych študijných programov, základy lekárskej a klinickej biochémie a oboznámiť ich s najčastejšie používanými metódami v biochemickom laboratóriu v primeranom rozsahu. Chce prispieť k prehĺbeniu vedomostí o metabolizme zdravého, ale i chorého človeka, resp. o klinicko-biochemických diagnostických postupoch a laboratórnych vyšetreniach a vzbudiť záujem o ďalšie vzdelávanie. Budeme radi, ak poslúži nielen ako príprava na skúšku, ale bude inšpiráciou napr. pre realizáciu diplomových prác zameraných na vedecko-výskumnú oblasť klinickej biochémie či laboratórnej medicíny. 

Autorky

Mária Mareková a kol. 

Medical biochemistry is integral parts of basic theoretic knowledge of contemporary graduate at medical faculties. This textbook intends to help the undergraduate students of study branches General Medicine and Dental Medicine for the course of “Medical Biochemistry”. It is structured into 10 chapters concerning several topics: enzymology, cells membrane, metabolism, biochemistry of blood and organs, as well as some parts of clinical biochemistry.

The theoretical knowledge of this subject, which student obtains in the lectures, is verified in laboratory practices and is expanded in seminaries. Our selection of topics makes the text especially appropriate for medical students and managing of problems gives the students satisfactory ground for effective study of medical biochemistry and other related study subjects (e.g. clinical biochemistry, physiology, pathophysiology) in the sense of comprehension of relative continuity and interdependence of biochemical process or their function respectively.

Since the textbook brings only the skeleton survey on the biochemical problematic concerning medicine, students should broaden presented facts by additional study from lectures and/or from other sources. We expect this study literature to serve as a basic study material for mentioned medical study branches for preparation to written part of exam from “Medical Biochemistry”.

Authors

E-book

Tatiana Kimáková - Vladimír Pavlík

The scientific monograph focuses on the characteristics of free radicals, reactive oxygen and nitrogen species, oxidative stress, and its impact on various diseases. A significant portion is dedicated to antioxidants, their classification based on multiple criteria, the characteristics of selected antioxidants in terms of their functions, manifestations of their deficiency and excess, and the overall antioxidant capacity of the body.

A special section is devoted to enzyme-based antioxidants, natural sources of antioxidants in the form of vitamins, trace elements, flavonoids, polyphenols, and coenzyme Q10. To provide a clearer understanding of antioxidants and their influence on population health, the monograph presents results from a research project included in the program "Research Support for Enhancing the Defense Capabilities of the Czech Republic in NATO Structures."

The research was conducted between 2010 and 2012 as part of preventive rehabilitation programs for professional soldiers with a sports component. The study involved 218 professional soldiers, including 180 men and 38 women, with an average age of 33.3 years. The current health status and dietary habits of the soldiers were assessed using questionnaires.

The study described the saturation of the observed group with antioxidant vitamins and statistically evaluated the relationship between their levels and the risk indicators for the development of cardiovascular diseases. Individual analyses were performed using the Reflotron device calibrated with Reflotron Precinorm control serum. Following blood collection, all participants underwent anthropometric examinations (body weight, height, waist circumference), blood pressure measurements, heart rate monitoring, and physical fitness assessments through simple functional tests.

This scientific monograph is suitable for the scientific community, students of medical, veterinary, and natural sciences, as well as public health students at all levels of university education. It is also intended for informed members of the public.

Authors

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E-publication

Štefan Tóth a kol.

After several years of teaching experience in the compulsory subject of histology and histological techniques, it became clear that there was a need to refine, standardize, and facilitate the study of bachelor's degree students. We therefore decided to develop university textbooks for the theory of general histology in bachelor's degree programs: Laboratory Examination Methods in Healthcare, Physiotherapy, and Nursing. The new textbooks are based on the syllabi for the subjects "Histology and Pathology" and "Fundamentals of Histology" for the given study programs. The content is designed to make the study of histology as easy as possible and to help students quickly orient themselves in the given topic. At the same time, the texts aim to streamline cooperation between students and teachers in lectures and practical exercises, emphasizing the important structures of individual cell and tissue types in light microscope images, which is the primary goal and task of general histology.

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Erik Dosedla

A uterine scar is currently a significant medical problem. Uterine scars most commonly occur after a Cesarean section, which is one of the most frequent laparotomic surgeries (Yazicioglu et al., 2006). The frequency of Cesarean sections increased between 1990 and 2014 in the USA from 21.2% to 32.2% (Hamilton et al., 2015), in Great Britain from 12% to 26.2% (NHS Maternity Statistics - England, 2013-14: Summary Report, 2015), and in the Slovak Republic from 8.7% to 31% (Národné centrum zdravotníckych informácii, 2016).

After a Cesarean section (CS), there is a risk of abnormal healing of the uterotomic wound, which can result in the development of certain pathological conditions in consecutive pregnancies (uterine rupture, ectopic pregnancy in the Cesarean scar, placental disorders) (Seow et al., 2004; Oyelese and Smulian, 2006; Fitzpatrick et al., 2012). In addition, a defect in the Cesarean scar is associated with chronic dysmenorrhea, chronic pelvic pain, infertility, and postmenstrual spotting (Wang et al., 2009; Bij de Vaate et al., 2011).

Ultrasound is a valuable examination method in the diagnostic and therapeutic management of these pathological conditions.

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 Terézia Hudáková - Jozef Židzik 

Pomocné učebné texty Biológia a genetika – pracovný zošit pre bakalárske študijné programy na praktické cvičenia z lekárskej biológie a genetiky sú určené predovšetkým pre študentov 1. ročníka bakalárskych odborov na UPJŠ LF v Košiciach (ošetrovateľstvo, fyzioterapia a verejné zdravotníctvo). Sú zamerané tak, aby vybranými praktickými úlohami a modelovými príkladmi vhodne dopĺňali, prehlbovali a ilustrovali látku, ktorú si študent vypočuje na prednáškach, alebo prečíta v učebnici. Dve základné oblasti pokryté v textoch sú cytológia a genetika.

Autori

E-book

Ladislav Kočan - Dušan Rybár - Róbert Rapčan

The autonomic nervous system is a vital component of the peripheral nervous system, responsible for maintaining homeostasis and regulating internal processes within the body. Unlike the voluntary control exerted by the central nervous system, the autonomic nervous system operates involuntarily, innervating smooth organs, vessels, skin glands, and even exerting some influence over skeletal muscles in connection with vegetative functions such as breathing, digestion, and the urinary and gonadal systems. Its impact extends crucially to the cardiac muscles of the heart and plays a significant role in endocrine and metabolic functions, thermoregulation, as well as emotional and behavioral responses, including adaptive reactions to stressors.

The aim of this publication is to provide a comprehensive and objective exploration of the anatomical and physiological intricacies of the autonomic nervous system, offering insights into its clinical applications. Within these pages, we meticulously delineate various interventional therapeutic procedures tailored to specific diagnoses related to the autonomic nervous system, aligning each intervention with the anatomical framework of the autonomic system. The efficacy of these procedures is evaluated based on the level of evidence, as per the current recommendations of Evidence-Based Medicine.

This publication is primarily crafted for fifth and sixth-year medical students and medical professionals specializing in anesthesiology, intensive care, and pain medicine. It serves as a valuable resource for gaining a deeper understanding of autonomic nervous system function and its clinical implications, facilitating informed decision-making in clinical practice.

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E-book

Jozef Židzik - Terézia Hudáková - Martina Šemeláková - Ján Šalagovič

Methods in human genetics and molecular biology encompass various experimental, diagnostic and analytical techniques used to investigate the structure, function, expression, and regulation of genes, as well as general molecular processes in human cells. The university textbook Methods in Human Genetics and Molecular Biology provides a comprehensive overview of classical and modern experimental and analytical procedures. In fifteen chapters, it addresses methods such as PCR, RFLP, FISH, Western blot, DNA sequencing, DNA microarrays, molecular cloning, cytogenetic analysis, and forensic genetic analysis. The book is primarily intended as study material for the course of the same name taught in the 2nd year of study at the UPJŠ Faculty of Medicine, but it can also be used by all university students in the fields of biology, biotechnology, and related disciplines.

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Alžbeta Blichárová - Ľudmila Verbóová - Zuzana Benetinová - Vladimír Tancoš  - Patrícia Kollárová  - Adam Nedoroščík - Erika Štammová  - Pavel Kočan

„Patológia 2. časť (letný semester) - Praktické cvičenia pre študentov všeobecného lekárstva“ je druhou časťou vysokoškolskej učebnice predstavujúcou druhú polovicu výučby (letný semester). V tejto časti je popísaných 70 diagnóz, kde každej je venovaná jedna strana. V popise je uvedené poradové číslo zhodujúce sa s číslom preparátu a názov danej diagnózy. Študent sa pri každom preparáte oboznámi so základnými informáciami o danej chorobe, jej makroskopickým a mikroskopickým obrazom. Navyše je vytvorené miesto, v ktorom si študent môže zaznačiť (nakresliť) charakteristický mikroskopický obraz danej choroby. Preparáty v tejto učebnici sú zamerané na špeciálnu patológiu – patológiu pľúc, hematopatológiu, patológiu gastrointestinálneho, urogenitálneho systému, prsníka, endokrinného, pohybového  a nervového systému, kože, novorodeneckého a detského veku.

Tým, že učebnica umožňuje preparáty zakresľovať, vytvára študentom priestor pre trvalejšie zapamätanie si danej problematiky. Je vynikajúcim zdrojom pre prípravu študentov na kolokvium a ústnu skúšku.

Peter Berek 

S vývojom endovaskulárnej chirurgie dochádza postupne k rozvoju stentingu ACI. Minimálne invazívny prístup spravil túto metodiku vhodnú pre pacientov s vážnymi konkomitatnými kardiálnymi alebo pľúcnymi ochoreniami. Ďalšou výhodou v porovnaní s chirurgickou liečbou bol lepší prístup k ACI u pacientov po rádioterapii, po predchádzajúcich operáciách na krku, ale aj u pacientov so stenózami blízko lebečnej bázy. Porovnanie CEA vs CAS je zaujímavou a diskutabilnou témou mnohých štúdií. Avšak, aj napriek celosvetovému mohutnému rozvoju endovaskulárnej liečby karotická endarterektómia ostáva zlatým štandardom liečby stenózy ACI u symptomatických aj asymptomatických pacientov.

V tejto monografii by sme radi akcentovali a systematizovali problematiku chirurgickej prevencie CMP z pohľadu cievneho chirurga.