Ochorenia obličiek v detskom veku vybrané kapitoly

E-book

Peter Berek

University scripts “Visceral pathology of vascular origin“analyze one of the most challenging vascular regions, the aorta and the visceral aortic branches, from the surgical perspective. The diagnostic and the treatment aneurysms of the abdominal aorta are dedicated to the first chapter. Early diagnostic and operative treatment is crucial in the treatment of ruptured aneurysms of the abdominal aorta. Shortening of the interval between the patient’s arrival with ruptured aneurysm of the abdominal aorta into the hospital and the beginning of the operation decreased the perioperative mortality. This shortening, together with the use of the cell savers, led to the dropping of perioperative mortality from 50% to 20%. The diagnostics and surgical treatment of the acute and chronic occlusion of the aorta and iliac arteries are analyzed in the second chapter. In this chapter, the focus is given to the aortobifemoral bypass as “the gold standard“ of the surgical therapy of aortoiliac atherosclerosis. The management of acute mesenteric ischemia is the content of the third chapter. Acute mesenteric ischemia is a severe condition with high mortality. The problem of acute mesenterial ischemia is a delayed diagnostic that is the reason for poor therapeutical outcomes of the disease. The possible imagine studies and operations used in treating acute mesenteric ischemia are brought in this chapter. Chronic mesenteric ischemia leads to cachexia. The diagnosis of chronic mesenterial ischemia is one of the most demanding, and surgical therapy used in the treatment of chronic mesenterial ischemia also belongs to the most challenging operations. Left-sided colon ischemia belongs to the severe complications of the aortoiliac reconstructions. Left-sided colon ischemia has a high mortality. In the prevention of the left-sided colon, ischemia is preserving at least one internal iliac artery. The complex diagnostics treatment of intraabdominal compressive syndromes as Dunbar syndróme, „Nutcracker“ syndróme a Wilkie syndróme, analyzed in the last chapter.

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E-book

Monika Halánová-Leonard Siegfried

Although chronic non-communicable diseases currently dominate overall morbidity and mortality in developed countries, epidemics of infectious diseases, especially those caused by new or emerging pathogens, occur more frequently and spread faster and further in new territories. The starting factors of this threat are mainly ecological and climatic changes and changes in human demography and behaviour. The growing resistance to ATB is also very serious, as a result of which there is a significant increase in the incidence of infectious diseases and their spread to new geographical locations. Current problems of epidemiology and microbiology in research and clinical practice are mainly focused on rapid detection and subsequent response to diagnosed diseases. The correct diagnosis of an infectious disease is the result of a clinical picture, knowledge of the current epidemiological situation and laboratory confirmation of the etiological agent. The identification of microorganisms allows us to establish the correct definitive diagnosis and subsequent targeted therapy, but also to start immediately with appropriate anti-epidemic measures to control the spread of the infectious agent.

Download e-book for free (pdf)

E-book

Ladislav Kočan-Dušan Rybár-Róbert Rapčan

The autonomic nervous system is a vital component of the peripheral nervous system, responsible for maintaining homeostasis and regulating internal processes within the body. Unlike the voluntary control exerted by the central nervous system, the autonomic nervous system operates involuntarily, innervating smooth organs, vessels, skin glands, and even exerting some influence over skeletal muscles in connection with vegetative functions such as breathing, digestion, and the urinary and gonadal systems. Its impact extends crucially to the cardiac muscles of the heart and plays a significant role in endocrine and metabolic functions, thermoregulation, as well as emotional and behavioral responses, including adaptive reactions to stressors. The aim of this publication is to provide a comprehensive and objective exploration of the anatomical and physiological intricacies of the autonomic nervous system, offering insights into its clinical applications. Within these pages, we meticulously delineate various interventional therapeutic procedures tailored to specific diagnoses related to the autonomic nervous system, aligning each intervention with the anatomical framework of the autonomic system. The efficacy of these procedures is evaluated based on the level of evidence, as per the current recommendations of Evidence-Based Medicine. This publication is primarily crafted for fifth and sixth-year medical students and medical professionals specializing in anesthesiology, intensive care, and pain medicine. It serves as a valuable resource for gaining a deeper understanding of autonomic nervous system function and its clinical implications, facilitating informed decision-making in clinical practice.

Download e-book for free (pdf)

Mária Mareková a kol.

Predkladaná vysokoškolská učebnica predstavuje základy biochémie a je určená predovšetkým pre bakalárske  študijné programy (napr. ošetrovateľstvo, fyzioterapia, verejné zdravotníctvo). Vysokoškolská učebnica predstavuje zjednodušenú alternatívu lekárskej biochémie a je svojím obsahom aj rozsahom vhodná pre študentov nelekárskych študijných odborov. Okrem priblíženia základných metabolických dejov prebiehajúcich v organizme človeka, ponúka aj stručný prehľad klinicko-biochemických parametrov štandardne vyšetrovaných pri podozrení na ich poruchy. Snaží sa poskytnúť študentom, predovšetkým zdravotníckych študijných programov, základy lekárskej a klinickej biochémie a oboznámiť ich s najčastejšie používanými metódami v biochemickom laboratóriu v primeranom rozsahu. Chce prispieť k prehĺbeniu vedomostí o metabolizme zdravého, ale i chorého človeka, resp. o klinicko-biochemických diagnostických postupoch a laboratórnych vyšetreniach a vzbudiť záujem o ďalšie vzdelávanie. Budeme radi, ak poslúži nielen ako príprava na skúšku, ale bude inšpiráciou napr. pre realizáciu diplomových prác zameraných na vedecko-výskumnú oblasť klinickej biochémie či laboratórnej medicíny. 

Autorky

Jozef Kafka

Význam vedomia pre každého človeka ale aj pre pozná­vanie je taký rozhodujúci, že by bolo nesprávne hovoriť o ňom iba pri psychických procesoch, lebo je jadrom ľudskej individuality a práve vedomím sa človek odlišuje od ostat­ných živých tvorov.

Je potešujúce, že nová oblasť poznávania označovaná ako veda o mysli začína sa vedomím zaoberať podrobnejšie a vylučuje tvrdenia, že vedomie nejestvuje hoci zatiaľ hovorí podľa mojej mienky iba o bazálnom vedomí a jej inter­pretácie prekračujú zistené fakty.

V svojej odbornej činnosti a aj v učebniciach som rozlišoval dve cesty poznávania vedomia a  iba postupne som si uvedomil, že mám pred sebou dva úrovne vedomia. V tejto práci  rozlišujem tieto dve úrovne:

• bazálne vedomie,
• rozvinuté vedomie.

Ak bazálne vedomie vyjadruje bdenie a spánok, tiež po­zornosť a gnostické rozpoznávanie, teda  idiognózia a somatognózia, rozvinuté vedomie predpokladá reč a vytvára také prejavy, ktoré označujeme ako duševné, teda identita, sebareali­záciu, čo vyjadruje schopnosť uvedomovania si seba, okolia, spoločnosti ale aj všetkého čo sme schopní poznať.

Také chápanie je blízke výkladu fyziológa Pavlova o dvoch signálnych sústavách a chápaniu Poppera o treťom sve­te ale aj ďalšie náhľady, nikto však neurobil určitejšie závery a nedošiel k náhľadu, že naše vedomie má dvojvrstevnú podobu, dve úrovne.

Napriek rozsiahlej a takmer neprehľadnej literatúre vieme o vedomí málo, okrem toho, že je to schopnosť uvedomo­vania, teda schopnosť uvedomiť si, že jestvujem, že som, že jest­vujú aj iní ľudia, že jestvuje niečo čo označujeme ako svet ako nepredstaviteľný vesmír. Uvedomujem si, že som individua­litou jedinečnou, ale limitovanou narodením a smrťou a že mám aj zmysel svojho bytia. Toto uvedomovanie, akokoľvek spo­chybňované je pre človeka prítomné v jeho poznávaní, hoci nemáme zmysly, ktorými by sme vedeli lokalizovať jeho prí­tomnosť v mozgu, ale svojou charakteristikou s dynamikou a integráciou má však duševný charakter, odlišný od    ostatných preja­vov mozgovej činnosti.

Práca sa pokúša v deviatich kapitolách osvetliť, čo sa chápe pojmom bazálne a rozvinuté vedomie    a možno ju rozdeliť do troch okruhov:

V prvých šiestich kapitolách diela hovorí o vedomí ako o doméne bytia človeka, podáva sa preto výklad vedomia a jeho rozlíšenie, potom sa hovorí o kolobehu života a rozvoji ve­domia, kladie sa otázka vedomia u stavovcov, potom náhľady filozofické a metodológia skúmania vedomia. Nasledujú ďalšie kapitoly, ktoré analyzujú podrobnejšie dve formy, úrovne vedomia, sú to kapitoly 7-9, začínajú ana­lýzou individuality človeka, lebo to je báza vedomia aj je­ho foriem, ďalej kapitoly o bazálnom vedomí a rozvinu­tom vedomí, čo považujem za jadro predkladanej práce. Napokon sa opisujú niektoré poruchy vedomia, ktoré dokladajú realitu vedomia v podobe  jej porúch ale aj možnosti rozlí­šenia dvoch úrovní, ktoré sa dajú zistiť pri starostlivom štúdiu a pri práci s chorými.

Roman Beňačka  a kolektív

Obsahovo i formou nová učebnica všeobecnej patofyziológie v slovenskom jazyku pre štúdium predmetu Patologická fyziológia pre odbor Všeobecné lekrástvo na lekárskych fakultách na Slovensku resp. v zahraniční. Nadväzuje na pedagogické skúsenosti s výučbou klasickej a molekulárnej patofyziológie a tradíciu vysokoškolských učebníc vydávaných Ústavom patofyziológie Lekárskej fakulty v Košiciach (prvá slovenská učebnica i učebnica Všeobecnej patofyziológie). Učebnica popisuje všetky základné témy z nozológie, etiológie a patogenzéy, ktoré sú tradične  predmetom výučby patofyziológie na lekárskych fakultách v európskom priestore. Prináša najnovšie poznatky štýlom i obsahovo v priamej konfrontácii s obdobnou cudzojazyčnou literatúrou a tp v čitateľsky rovnako atraktívnej prezentačnej forme s početnými obrázkami a tabuľkami.

E-book

Ján Varga

The cancer is the second most common reason of the death in human population. lt is responsible for approximately 10 million of death every year. Oncogynecology represents · one of the most pr ogressive part of gynecology. The interest is focused on vulvar cancer, vaginal cancer, cervical cancer, uterine cancer, fallopian tube carcinoma, ovarian cancer as well as breast cancer. Due to the range of the issue there are own workplaces ta king care just for the patients with oncogyneco logical diseases. The knowledge from oncogynecology are inevitably needed to pass the state exam as well as specialization from Gynecology and obstetrics. The presented publication is focused to mentioned oncogynecological diseases.

The anatomy and histology of the vulva, vagína, cervix, uterus, fallop ian tube and ovary are described in detail. Every described carcinoma contains part about etiopathogenesis, clinical presentation, diagnostic, classification and therapy. The paper contains information suitable for students of medical faculties as well as young doctors before specialization.

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Darina Kluchová 

E-book

A.A. Ahmetova - A.A. Seidakhmetova - N.D. Kalmenov et al.

Improving the best practices in the provision of the first pre-medical care is one of the priority areas of clinical medicine in most countries of the world. Despite the success in improving the provision of medical care at the level of FPMA and emergency medical care, it is the provision of skilled care at the earliest stages of the disease or emergency conditions that determines the quality of all medical care and the future of the patient.

When rendering emergency care to the sick and injured, the time factor is very important, it prevents irreversible disturbances in the body and creates a good help for the complete cure of the patient. Textbook is designed to improve awareness of the importance of pre-medical aid to non-medical students in central Asian countries.

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E-book

I. R. Mavlyanov - A. K. Ashirmetov - Z. I. Mavlyanov - G. J. Jarilkasinova

Need of carrying out a pharmacological genotyping for providing the individualized pharmacotherapy is shown in the monograph based on the analysis of own and literary data of the central link of drug pharmacokinetics– systems of cytochrome P-450, taking into account its genetic polymorphysm.
The monograph is intended for the clinical pharmacologists, geneticists and experts dealing with this problem.

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 John B. West - Andrej Andrašovský

West’s Respiratory Physiology: The Essentials is the gold standard text for learning respiratory physiology quickly and easily. This highly readable, must-have text serves as an introduction to students and a review for licensing and other exams. The Tenth Edition features the addition of Dr. Andrew M. Luks as co-author along with new clinical vignettes, additional multiple-choice review questions, and updated information on key topics in respiratory physiology, such as blood flow and metabolism, gas transport by the blood, and the physiology of high altitude.

• New! Clinical vignettes with questions emphasize how the physiology described can be applied to clinical situations and reinforce reasoning and critical thinking.
• More than 100 multiple-choice questions with full explanations provide self-testing of key concepts for comprehension and exam preparation.
• Clinical boxes and Key Concepts summaries provide bullet-point reviews.
• Appendices of important equations and answers to all questions are easily referenced.
• Online resources include animations that expand on and clarify challenging topics, an interactivequestion bank, and lectures by Dr. West.

Martina Zavacká a kolektív

Kniha „DIABETICKÁ NOHA Z POHĽADU CIEVNEHO CHIRURGA“ obsahuje 14 kapitol. Pojednáva o syndróme diabetickej nohy z multidisciplinárneho pohľadu viacerých odborníkov: angiochirurga, diabetológa, chirurga, podiatra, röntgenológa, neurológa a algeziológa. Úvodné kapitoly majú charakter propedeutiky, čo má taktiež význam aj pre pregraduálnu výchovu. Nasledujúce kapitoly sa zaoberajú vznikom syndrómu, výskytom, jeho diagnostikou, terapeutickými postupmi, pridruženými postihnutiami neurologického charakteru, starostlivosťou podiatra a algeziológa pri pretrvávaní bolestí. Ďalšie časti sú vyhradené chirurgickej a endovaskulárnej liečbe tepien cestou cievneho chirurga a intervenčných angiológov. Nezabúdajúc na problematiku amputácií a správnu rehabilitáciu pacientov s diabetom.  V knihe nájdu poučenie cievni chirurgovia, angiológovia, všeobecní chirurgovia, diabetológovia, neurológia, röntgenológovia, podiatri  a všeobecní lekári.

Kniha je zdrojom najnovších teoretických i praktických informácií pre postgraduálnu výchovu vyššie spomenutých odborníkov.

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E-book

Magdaléna Hagovská - Alena Buková - Ľubomír Lachváč

Overweight as a risk factor for the development of civilization diseases and urogenital dysfunctions

Overweight and obesity represent a significant risk factor for the development of several diseases of civilisation, such as cardiovascular disease, type 2 diabetes mellitus and various forms of cancer. They also contribute significantly to urogenital dysfunctions such as urinary incontinence, overactive bladder and pelvic organ prolapse. Mechanisms that link excess weight to these dysfunctions include increased intra-abdominal pressure, hormonal changes, and chronic inflammatory processes that negatively affect the structure and function of the urogenital system. Prevention and treatment of overweight and obesity are therefore crucial not only in terms of reducing the risk of civilization diseases, but also in improving the quality of life through the prevention and treatment of urogenital dysfunctions.

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E-book

Eva Ďurovcová - Mária Mareková

Clinical Biochemistry - selected chapters - MEFANET >>> 

After 7 years, we finally reworked the textbook on the subject of clinical biochemistry at UPJŠ FM in Košice. We have innovated information in accordance with recommendations of professional medical societies and added new chapters. As the scope of the subject is limited, the textbook does not cover all issues of biochemical diagnostics. It focuses on disorders of water-ion and acid-base balance disorders, and basic laboratory diagnostics of diseases of selected organs.

The textbook of clinical biochemistry has the ambition to become a practical aid for senior medical students and beginning doctors in the study of laboratory medicine. It should make it easier for them to orientate themselves in routinely used clinical-biochemical examinations and could form a springboard for a more detailed studying of laboratory methods and their use in diagnostic and monitoring algorithms.
Like any medical discipline, clinical biochemistry is evolving rapidly and gradually integrating with other areas of laboratory medicine. New diagnostic methods penetrate deeper into the essence of the biochemical mechanisms of the human body, and "omic" methods are gaining ground. It is almost sure that in a few years, laboratory examination looks quite different from today. If this publication quite hypothetically reaches its next edition, many chapters will need to updated, and new chapters written following the up-to-date status.
Authors thanks to their colleagues and reviewers for their professional comments and constructive criticism of the text - prof. Jaroslav Racek, MD, DrSc. from FM UK in Pilsen.
Authors thanks very kindly too prof. MUDr. Dušan Dobrota, CSc. (JFM UK Martin) and doc. MVDr. Zuzana Kostecká, PhD. (UVMP, Košice), who read and wrote review of this textbook.

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E-book

Mária Sováriová Soósová a kol.

The proposed university textbook provides knowledge in the field of nursing in internal medicine. It is intended primarily for students of the nursing program, but also for nurses working in this specialization. The textbook builds on the previous two parts: Nursing Process in Internal Medicine I (Sováriová Soósová, 2006) and Nursing Process in Internal Medicine II (Suchanová, 2007). It is divided into four chapters, focusing on disorders of water and electrolyte balance and acid-base equilibrium, kidney and urinary tract diseases, endocrine system diseases, and musculoskeletal disorders.

Each chapter is similarly structured, beginning with diagnostic methods commonly used in the respective area. Subsequent subchapters address nursing care for selected diseases of specific bodily systems. Each subchapter consists of a clinical introduction (characteristics of the disease, its etiology, clinical presentation, diagnosis, and treatment) and nursing care for the given disease. This includes assessment, formulation of nursing diagnoses, and planning nursing care (setting goals, outcome criteria, and planning possible interventions).

The textbook serves as a model framework and algorithm for managing nursing care using the nursing process method.

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E-book

Peter Berek

University scripts “Visceral pathology of vascular origin“analyze one of the most challenging vascular regions, the aorta and the visceral aortic branches, from the surgical perspective. The diagnostic and the treatment aneurysms of the abdominal aorta are dedicated to the first chapter. Early diagnostic and operative treatment is crucial in the treatment of ruptured aneurysms of the abdominal aorta. Shortening of the interval between the patient’s arrival with ruptured aneurysm of the abdominal aorta into the hospital and the beginning of the operation decreased the perioperative mortality. This shortening, together with the use of the cell savers, led to the dropping of perioperative mortality from 50% to 20%. The diagnostics and surgical treatment of the acute and chronic occlusion of the aorta and iliac arteries are analyzed in the second chapter. In this chapter, the focus is given to the aortobifemoral bypass as “the gold standard“ of the surgical therapy of aortoiliac atherosclerosis. The management of acute mesenteric ischemia is the content of the third chapter. Acute mesenteric ischemia is a severe condition with high mortality. The problem of acute mesenterial ischemia is a delayed diagnostic that is the reason for poor therapeutical outcomes of the disease. The possible imagine studies and operations used in treating acute mesenteric ischemia are brought in this chapter. Chronic mesenteric ischemia leads to cachexia. The diagnosis of chronic mesenterial ischemia is one of the most demanding, and surgical therapy used in the treatment of chronic mesenterial ischemia also belongs to the most challenging operations. Left-sided colon ischemia belongs to the severe complications of the aortoiliac reconstructions. Left-sided colon ischemia has a high mortality. In the prevention of the left-sided colon, ischemia is preserving at least one internal iliac artery. The complex diagnostics treatment of intraabdominal compressive syndromes as Dunbar syndróme, „Nutcracker“ syndróme a Wilkie syndróme, analyzed in the last chapter.

Download e-book for free (pdf)

E-book

Monika Halánová-Leonard Siegfried

Although chronic non-communicable diseases currently dominate overall morbidity and mortality in developed countries, epidemics of infectious diseases, especially those caused by new or emerging pathogens, occur more frequently and spread faster and further in new territories. The starting factors of this threat are mainly ecological and climatic changes and changes in human demography and behaviour. The growing resistance to ATB is also very serious, as a result of which there is a significant increase in the incidence of infectious diseases and their spread to new geographical locations. Current problems of epidemiology and microbiology in research and clinical practice are mainly focused on rapid detection and subsequent response to diagnosed diseases. The correct diagnosis of an infectious disease is the result of a clinical picture, knowledge of the current epidemiological situation and laboratory confirmation of the etiological agent. The identification of microorganisms allows us to establish the correct definitive diagnosis and subsequent targeted therapy, but also to start immediately with appropriate anti-epidemic measures to control the spread of the infectious agent.

Download e-book for free (pdf)

E-book

Ladislav Kočan-Dušan Rybár-Róbert Rapčan

The autonomic nervous system is a vital component of the peripheral nervous system, responsible for maintaining homeostasis and regulating internal processes within the body. Unlike the voluntary control exerted by the central nervous system, the autonomic nervous system operates involuntarily, innervating smooth organs, vessels, skin glands, and even exerting some influence over skeletal muscles in connection with vegetative functions such as breathing, digestion, and the urinary and gonadal systems. Its impact extends crucially to the cardiac muscles of the heart and plays a significant role in endocrine and metabolic functions, thermoregulation, as well as emotional and behavioral responses, including adaptive reactions to stressors. The aim of this publication is to provide a comprehensive and objective exploration of the anatomical and physiological intricacies of the autonomic nervous system, offering insights into its clinical applications. Within these pages, we meticulously delineate various interventional therapeutic procedures tailored to specific diagnoses related to the autonomic nervous system, aligning each intervention with the anatomical framework of the autonomic system. The efficacy of these procedures is evaluated based on the level of evidence, as per the current recommendations of Evidence-Based Medicine. This publication is primarily crafted for fifth and sixth-year medical students and medical professionals specializing in anesthesiology, intensive care, and pain medicine. It serves as a valuable resource for gaining a deeper understanding of autonomic nervous system function and its clinical implications, facilitating informed decision-making in clinical practice.

Download e-book for free (pdf)

Mária Mareková a kol.

Predkladaná vysokoškolská učebnica predstavuje základy biochémie a je určená predovšetkým pre bakalárske  študijné programy (napr. ošetrovateľstvo, fyzioterapia, verejné zdravotníctvo). Vysokoškolská učebnica predstavuje zjednodušenú alternatívu lekárskej biochémie a je svojím obsahom aj rozsahom vhodná pre študentov nelekárskych študijných odborov. Okrem priblíženia základných metabolických dejov prebiehajúcich v organizme človeka, ponúka aj stručný prehľad klinicko-biochemických parametrov štandardne vyšetrovaných pri podozrení na ich poruchy. Snaží sa poskytnúť študentom, predovšetkým zdravotníckych študijných programov, základy lekárskej a klinickej biochémie a oboznámiť ich s najčastejšie používanými metódami v biochemickom laboratóriu v primeranom rozsahu. Chce prispieť k prehĺbeniu vedomostí o metabolizme zdravého, ale i chorého človeka, resp. o klinicko-biochemických diagnostických postupoch a laboratórnych vyšetreniach a vzbudiť záujem o ďalšie vzdelávanie. Budeme radi, ak poslúži nielen ako príprava na skúšku, ale bude inšpiráciou napr. pre realizáciu diplomových prác zameraných na vedecko-výskumnú oblasť klinickej biochémie či laboratórnej medicíny. 

Autorky