Rádiológia pre lekárske fakulty

E-book

Tatiana Kimáková a kol.

Ethics, as the science of the proper realization of human potential in various areas of life, also extends into the environment. For understanding the ethical aspects in this field, a thorough knowledge of the individual components of the environment, as well as their impact not only on humans but on all living nature, is very important. Therefore, questions concerning the influence of the environment are increasingly at the forefront of interest from an ethical perspective, also in connection with existing legal norms.

The modern process of civilization is characterized by rapid development of science and technology. However, this development, while raising the standard of living on one hand, also brings negative side effects on the other. The result is the disruption of ecological, biological, and natural life conditions, especially in the areas of industrial centers. The development of individual branches of industry leads to the production of liquid, gaseous, and solid wastes, the emergence of harmful risk factors threatening various components of living nature, including humans. There may be increased bioaccumulation of hazardous chemical elements in organisms, which, through their effects, represent a potential risk also in terms of carcinogenesis and mutagenesis.

For this reason, an important role of society is to create conditions to prevent the release of emissions and to reduce their concentration to the lowest possible, socially and biologically acceptable level. The assessment of the biological effects of harmful substances is based on experimental and epidemiological studies. Knowledge of concentration and duration of exposure is crucial for applying dose-effect relationships and for determining the highest permissible concentrations of pollutants. The health of the population, as a universal value and a primary human right, represents a fundamental economic resource not only for the individual, but also for society as a whole.

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Lucia Dimunová - Jana Michalková - Gabriela Štefková - Mária Zamboriová

Following innovative trends in university education, this academic textbook offers guidance to update and make the educational process more attractive for all healthcare professions. It applies critical thinking and strategic method of concept mapping in teaching, which are suitable tools for the facilitator and the educant to achieve the desired goal. Critical thinking is an essential academic skill upon which other knowledge and intellectual virtues can be built. It is also an essential equipment for every graduate of the healthcare profession.

The textbook is complemented by a chapter focusing on methods for structural and formative assessment of learning outcomes. The publication is also enriched with sample digital concept maps of which cognitive content can be edited and graphically modified.

The aim of this academic textbook is to present a way of acquiring knowledge through critical thinking using concept mapping as a method, with the final goal of implementing the acquired knowledge into everyday practice.

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Ján Varga

The cancer is the second most common reason of the death in human population. lt is responsible for approximately 10 million of death every year. Oncogynecology represents · one of the most pr ogressive part of gynecology. The interest is focused on vulvar cancer, vaginal cancer, cervical cancer, uterine cancer, fallopian tube carcinoma, ovarian cancer as well as breast cancer. Due to the range of the issue there are own workplaces ta king care just for the patients with oncogyneco logical diseases. The knowledge from oncogynecology are inevitably needed to pass the state exam as well as specialization from Gynecology and obstetrics. The presented publication is focused to mentioned oncogynecological diseases.

The anatomy and histology of the vulva, vagína, cervix, uterus, fallop ian tube and ovary are described in detail. Every described carcinoma contains part about etiopathogenesis, clinical presentation, diagnostic, classification and therapy. The paper contains information suitable for students of medical faculties as well as young doctors before specialization.

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E-book

Peter Fedoročko (eds.)

From June 14 to June 17, 2022, the 8th annual Spring School for Doctoral Students at Pavol Jozef Šafárik University in Košice will take place in Liptovský Ján. The scientific program of the spring school will comprise 3 plenary lectures by leading scientific experts and 1 workshop. Doctoral students will present their research papers in two sections: 22 doctoral students of Faculty of Public Administration, Faculty of Law and Faculty of Arts, and 26 doctoral students of Faculty of Medicine and Faculty of Science. The scientific programme of the spring school will also include a panel discussion with the management of Pavol Jozef Šafárik University in Košice.

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Magdaléna Hagovská - Alena Buková - Ľubomír Lachváč

Overweight as a risk factor for the development of civilization diseases and urogenital dysfunctions

Overweight and obesity represent a significant risk factor for the development of several diseases of civilisation, such as cardiovascular disease, type 2 diabetes mellitus and various forms of cancer. They also contribute significantly to urogenital dysfunctions such as urinary incontinence, overactive bladder and pelvic organ prolapse. Mechanisms that link excess weight to these dysfunctions include increased intra-abdominal pressure, hormonal changes, and chronic inflammatory processes that negatively affect the structure and function of the urogenital system. Prevention and treatment of overweight and obesity are therefore crucial not only in terms of reducing the risk of civilization diseases, but also in improving the quality of life through the prevention and treatment of urogenital dysfunctions.

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Radoslav Morochovič - Rastislav Burda -

Ľuboš Tomčovčík - Peter Cibur - Štefan Ivanecký

Vysokoškolský učebný text určený pre študentov všeobecného lekárstva, zubného lekárstva a fyzioterapie, ktorý obsahuje podstatné časti z predmetu úrazová chirurgia potrebných na zvládnutie vysokoškolského štúdia.

E-book

Peter Berek

University scripts “Visceral pathology of vascular origin“analyze one of the most challenging vascular regions, the aorta and the visceral aortic branches, from the surgical perspective. The diagnostic and the treatment aneurysms of the abdominal aorta are dedicated to the first chapter. Early diagnostic and operative treatment is crucial in the treatment of ruptured aneurysms of the abdominal aorta. Shortening of the interval between the patient’s arrival with ruptured aneurysm of the abdominal aorta into the hospital and the beginning of the operation decreased the perioperative mortality. This shortening, together with the use of the cell savers, led to the dropping of perioperative mortality from 50% to 20%. The diagnostics and surgical treatment of the acute and chronic occlusion of the aorta and iliac arteries are analyzed in the second chapter. In this chapter, the focus is given to the aortobifemoral bypass as “the gold standard“ of the surgical therapy of aortoiliac atherosclerosis. The management of acute mesenteric ischemia is the content of the third chapter. Acute mesenteric ischemia is a severe condition with high mortality. The problem of acute mesenterial ischemia is a delayed diagnostic that is the reason for poor therapeutical outcomes of the disease. The possible imagine studies and operations used in treating acute mesenteric ischemia are brought in this chapter. Chronic mesenteric ischemia leads to cachexia. The diagnosis of chronic mesenterial ischemia is one of the most demanding, and surgical therapy used in the treatment of chronic mesenterial ischemia also belongs to the most challenging operations. Left-sided colon ischemia belongs to the severe complications of the aortoiliac reconstructions. Left-sided colon ischemia has a high mortality. In the prevention of the left-sided colon, ischemia is preserving at least one internal iliac artery. The complex diagnostics treatment of intraabdominal compressive syndromes as Dunbar syndróme, „Nutcracker“ syndróme a Wilkie syndróme, analyzed in the last chapter.

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Lucia Dimunová et al.

Nutrition is among the fundamental needs of humans. A good nutritional status directly impacts an individual’s growth and development, health maintenance, and quality of life. This university textbook addresses nutrition in the context of dietetics and therapeutic nutrition, offering an overview of basic food components such as proteins, fats, carbohydrates, vitamins, and minerals.

It provides detailed insights into nutritional requirements across different developmental stages. In assessing nutritional status, it explores evaluation methods, including nutritional screening, anthropometric measurements, clinical assessments, and laboratory tests.

The text clarifies the structure of nutritional care systems for patients in home settings, healthcare facilities, and social institutions through a unified dietary system that defines basic and specialized diets. Alternative nutrition methods are discussed separately, with enteral and parenteral nutrition serving as alternatives during unfavorable health conditions.

The authors focus on application techniques and complications associated with these methods. The book concludes with food safety considerations and foundational principles of the European Union’s food policy. Currently, dietetics and therapeutic nutrition form a critical component of professional training for healthcare students in both undergraduate and postgraduate education, for whom this textbook is designed.

Authors’ Collective

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Martina Vidová Ugurbas

Plastická chirurgia je vysoko špecializovaný medicínsky odbor, ktorý sa zaoberá korekciou defektov, rekonštrukciou a zdokonaľovaním ľudského tela.

Náplňou plastickej chirurgie je korekcia rôznych defektov, vrodených i získaných. Medzi vrodené chyby patria deformity tváre, rázštepy pery a podnebia, deformity ušnice, vrodené vývojové chyby končatín. Najčastejšie získané defekty sú po poraneniach, po chirurgických výkonoch, po fyzikálnych poškodeniach kože a štruktúr krytých kožou.

Do plastickej chirurgie patrí i estetická chirurgia, onkochirurgia a mikrochirurgia, ktorá si zaslúži osobitnú pozornosť. Novými trendami v estetickej chirurgii je rekonštrukcia pomocou tukového tkaniva, kmeňových buniek, používanie rôznych umelých materiálov a implantátov.

Predložené učebné texty v jednotlivých kapitolách popisujú základné princípy plastickej chirurgie, používanie lalokových plastík a iné možnosti krytia defektov. V ôsmych kapitolách sú jednotlivo popísané chirurgické možnosti rekonštrukcie tváre, trupu a končatín. Učebné texty venujú pozornosť malígnym a benígnym kožným tumorom a ich liečbe. Posledná kapitola sa zaoberá najčastejšími estetickými operáciami ako sú augmentácia a redukcia prsníkov, facelifting či blefaroplastika.

E-book

Jozef Židzik - Terézia Hudáková - Martina Šemeláková - Ján Šalagovič

Methods in human genetics and molecular biology encompass various experimental, diagnostic and analytical techniques used to investigate the structure, function, expression, and regulation of genes, as well as general molecular processes in human cells. The university textbook Methods in Human Genetics and Molecular Biology provides a comprehensive overview of classical and modern experimental and analytical procedures. In fifteen chapters, it addresses methods such as PCR, RFLP, FISH, Western blot, DNA sequencing, DNA microarrays, molecular cloning, cytogenetic analysis, and forensic genetic analysis. The book is primarily intended as study material for the course of the same name taught in the 2nd year of study at the UPJŠ Faculty of Medicine, but it can also be used by all university students in the fields of biology, biotechnology, and related disciplines.

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Iveta Domoráková - Štefan Tóth - Zuzana Fagová - Eva Mechírová - Alexandra Kunová - Kristína Čurgali - Viera Eliášová - Monika Holodová - Marianna Danková

In our new electronic textbook, FUNDAMENTALS OF HISTOLOGY II – Textbook and Atlas of Microscopic Anatomy of Organs, we present students and the professional public with essential information about the microscopic structure of organs, accompanied by extensive visual documentation of organ structures and clear legends for the microphotographs.

All histological specimens come from the archive of the Institute of Histology and Embryology, are used in practical exercises, and are also included in teaching presentations. The electronic textbook is intended for undergraduate and postgraduate students of general medicine and dentistry at medical faculties, as well as for students of veterinary medicine and pharmacy, and biology students at faculties of natural sciences.

The textbook is designed so that students can find clear explanations of most medical terms and also reinforce their knowledge of professional terminology in Latin. An advantage of the electronic textbook is the ability to enlarge microscopic photographs, allowing detailed observation of structures without any qualitative loss of the viewed image. The microphotographs used in the atlas were taken with the following equipment: Zeiss Promicra and Olympus BX50 with a Canon EOS 2000D digital camera and QP Industrial 3.2 software.

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Eva Slabá - Jozef Židzik a kolektív

Vysokoškolská učebnica „Lekárska biológia a genetika“ poskytuje v zrozumiteľnej podobe teoretické základy bunkovej biológie, molekulovej biológie a genetiky. Obsahuje najnovšie poznatky z relevantných odborov doplnené názornými obrázkami, tabuľkami a grafmi. Prehľadne členené kapitoly zoznámia študentov s problematikou bunkovej biológie, procesov molekulovej biológie a zákonitosťami genetiky. Vysokoškolská učebnica je určená predovšetkým pre slovenských študentov I. ročníka lekárskych fakúlt. Jej obsah je podkladom pre úspešné zvládnutie obsahovej náplne predmetu biológia. Učebnica je vhodná aj ako hlavný zdroj informácií pre študentov prírodovedeckých fakúlt. Okrem základných údajov obsahujú niektoré kapitoly aj doplňujúce informácie pre lepšie pochopenie jednotlivých tematických okruhov. Tieto podrobnejšie údaje sú odlíšené veľkosťou písma a nie sú nevyhnutné pre zvládnutie skúšky z biológie. Príslušné informácie však môžu využiť i študenti vyšších ročníkov lekárskych fakúlt či študenti postgraduálneho štúdia.

Ingrid Babinská - Monika Halánová

Epidemiológia je samostatný vedný odbor, ktorý sa zaoberá štúdiom procesu vzniku a šírenia ochorení, navrhuje opatrenia na ochranu a zlepšenie zdravia a kontroluje ich účinnosť. Jej hlavným cieľom je prispievať k znižovaniu chorobnosti a úmrtnosti, k ochrane a upevňovaniu zdravia, ako aj k predĺženiu života a zlepšeniu jeho kvality u jednotlivcov a v populácii.

Aj napriek tomu, že dominantné postavenie v celkovej morbidite a mortalite vo vyspelých krajinách majú v súčasnosti chronické neinfekčné ochorenia, epidémie infekčných ochorení sa vyskytujú stále. Dnešná doba so sebou prináša nové hrozby, ktorým musí epidemiológia, ale aj iné vedné odbory (napr. verejné zdravotníctvo, infektológia, cestovná medicína a pod.) čeliť. Ide najmä o infekcie vyvolané novými alebo novo sa objavujúcimi patogénmi, zmeny životného prostredia a životného štýlu, klimatické zmeny, rastúca rezistencia na antibiotiká, odmietanie očkovania, chudoba a pod.

Prvý diel predkladaných učebných textov prináša informácie týkajúce sa epidemiologického vyšetrovania v ohnisku nákazy, prehľad o klasifikácii infekčných chorôb z pohľadu epidemiológa a podrobnejšie sa venuje problematike črevných nákaz. Samostatná kapitola je venovaná modelovým situáciám, ktoré prispejú k pochopeniu danej problematiky a zvládnutiu obdobných situácií priamo v praxi.    

Učebné texty sú prioritne určené študentom bakalárskeho a magisterského štúdia odboru Verejné zdravotníctvo, ale určite si v ňom množstvo informácii nájdu aj študenti Všeobecného lekárstva a študenti ďalších bakalárskych a magisterských odborov Lekárskej fakulty UPJŠ v Košiciach.

Mária Frankovičová - Jana Kaťuchová - Jozef Radoňak a kol.

Vysokoškolská učebnica určená študentom všeobecného lekárstva, ktorá predstavuje kompaktný zdroj informácií nevyhnutných pre úspešné zvládnutie štúdia predmetu chirurgia. Obsahuje kapitoly z chirurgickej propedeutiky, chirurgie krku, hrudníka a brucha, ako aj nadstavbových chirurgických odborov, vrátane traumatológie, neurochirurgie, ortopédie, urológie, cievnej, plastickej, detskej chirurgie a kardiochirurgie.

Alžbeta Blichárová a kolektív

“Pathology Part 1 (winter semester) - Practical lessons for students of general medicine” represents the first half of the university textbook designed for the pregradual study of pathology. The textbook complements the lectures of pathology and serves as a source of information for students of general medicine, that are preparing for the practical as well as the final oral examination.

In this part of the “Pathology” series, seventy selected histopathological slides are presented. Each selected slide is provided with general information in relation to etiology and pathogenesis of the disease, as well as with corresponding morphological features, including the gross appearance and the most important histopathological characteristics. The textbook summarizes the basic concepts of general pathology that are necessary to master the broad field of systemic pathology in the second semester.

Keywords: general pathology – histopathological slides – general medicine – gross appearance – microscopic image

Miroslav Gajdoš - Igor J.Šulla a kol. 

Učebnica pre lekárov a študentov všeobecného lekárstva

Medicína je neprestajne sa vyvíjajúca vedná disciplína. Základný výskum v spojení s klinickou praxou rozširujú súčasné vedomosti, čo sa veľmi výrazne prejavuje aj v neurovedách, v praktickej podobe hlavne v neurofyziológii, neurofarmakológii, neurológii, diagnostickej aj intervenčnej neurorádiológii a v neurochirurgii. V priebehu ostatných troch desaťročí neurovedy prekonali pozoruhodný vývoj. Podnietili ho potreby praxe a umožnilo využitie poznatkov biológie, chémie, biochémie, aplikovanej matematiky, výpočtovej techniky a fyzikálnych objavov realizovaných v moderných prístrojoch i liečebných postupoch. To všetko podstatne uľahčilo, spresnilo a urýchlilo diagnostiku ochorení nervového systému, umožnilo relatívne bezpečné chirurgické zásahy na štruktúrach v minulosti nedostupných a otvorilo nové perspektívy, hlavne v oblasti reparácie poškodených tkanív, respektíve ich funkcií autotransplantáciou kmeňových/progenitorových buniek, terapeutickými zásahmi na genómovej, prípadne proteómovej úrovni. Ako vysokoškolskí učitelia sa každodenne stretávame nielen s mimoriadnym záujmom študentov i zdravotníckych pracovníkov o nové poznatky, ale aj s určitou neistotou pri posudzovaní možností, ktoré jednotlivé disciplíny patriace do skupiny neurovied ponúkajú. Jednou z príčin spomenutého javu je pravdepodobne časový faktor, keď najnovšie poznatky ešte nestačili preniknúť do odbornej literatúry, alebo v nej nie sú dostatočne zdôraznené. Druhou príčinou môže byť pomerne malá skúsenosť s niektorými ochoreniami nervového systému, ktoré sa síce vyskytujú zriedkavejšie, ale ich následky sú závažné. Cieľ, ktorý sme sledovali napísaním tejto učebnice, bolo aspoň čiastočne odstrániť spomenuté nedostatky všetkých odborných publikácií.

Počas prípravy rukopisu sme sa snažili, aby terapeutické postupy, názvy liekov a ich dávkovanie boli v súlade s najnovšími poznatkami vedy a klinickej praxe. Oprávnene však môžeme predpokladať, že budúce objavy zmenia súčasný pohľad na problematiku diagnostiky aj liečby ochorení nervového systému.

Vysokoškolská učebnica je určená študentom všeobecného lekárstva UPJŠ Lekárskej fakulty v Košiciach a lekárom, zameraným hlavne na všeobecné lekárstvo.

Kolektív autorov