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TEXTBOOK OF MEDICAL CHEMISTRY

TEXTBOOK OF MEDICAL CHEMISTRY

E-book

E-book

Lucia Andrezálová, Zdeňka Ďuračková,Mária Chomová,Vladimír Jakuš, Miriam Ježovičová, Jana Muchová, Zuzana Országhová,Ingrid Žitňanová

Chemistry and biochemistry at medical faculties are integral parts of basic theoretic knowledge of contemporary graduate. Educational book “Textbook of Medical Chemistry” is destined to students of study branches General Medicine and Dentistry for the course “Medical Chemistry”.

It is structured into 13 chapters concerning several topics: general and physical chemistry, organic chemistry, chemistry of natural substances (static biochemistry), enzymology and oxidative stress.

Individual chapters provide comprehensible explanation of the fundamentals of physico-chemical, chemical and biochemical relationships applying in living systems as well as the knowledge of the structure of biologically important molecules (simple molecules and macromolecules) related to their properties and biological function.

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Štruktúra a fyzikálno-chemické vlastnosti imunoglobulínov

Štruktúra a fyzikálno-chemické vlastnosti...

E-book

E-book

Gabriel Žoldák

The textbook is intended as background material for university students and for education in science, biotechnology, and medicine. During the textbook conception, the emphasis was on recent trends and development in the understanding of the physicochemical properties of immunoglobulins.

The textbook is divided into ten chapters and 294 pages dealing with the following topics: Immune system and immunoglobulins, General properties of immunoglobulins, Chemical and proteolytic cleavage of immunoglobulins, Structure of immunoglobulins I, Structure of immunoglobulins II, Detection of immunoglobulins, Post-purification and purification immunoglobulin modifications, Immunoglobulin stability and aggregation, Therapeutic immunoglobulins. In addition to the summary of the established knowledge about the properties of immunoglobulins, the textbook also contains new information collected from recent scientific publications.

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Základné laboratórne cvičenia z anorganickej chémie

Základné laboratórne cvičenia z anorganickej...

E-book

E-book

Zuzana VargováMiroslav Almáši - Juraj KuchárJana Dinajová 

The script „Základné laboratórne praktikum z anorganickej chémie“ builds on previous editions of the script, with some thematic units updated and supplemented with new knowledge, principles, and detailed work procedures.

This script is intended as a teaching aid for first-year students of the chemistry and interdisciplinary study programs at the Faculty of Science, Pavol Jozef Šafárik University in Košice. The introductory part of the volume acquaints students with safety regulations that they should follow during work in a chemical laboratory. Subsequently, in five chapters, basic laboratory techniques are described in detail, which students will use in the further part of the practices for preparing inorganic compounds. These chapters are enriched with illustrative images created using the freely distributable ACDFreeLabs 10 program or taken from literature listed at the end of the script. Some images were created by the authors, and others were taken from the catalog of Fisher Slovakia, s.r.o., which provided written permission for their use. The chapters describing the preparation of inorganic compounds are organized according to their composition, from simple elements or molecules, through binary compounds, acids, and salts, to complex compounds.

Within this subject, students should apply their theoretical knowledge gained during lectures on General Chemistry and Inorganic Chemistry and thereby acquire basic practical experience and skills that they will use in further studies.

The last two chapters were developed based on cooperation with Duslo a.s., Production Plant Strážske, which participates in the innovation of practical teaching through direct involvement of experts from practice as part of the KEGA project No. 008UPJŠ-4/2018.

Authors

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Praktikum z molekulového modelingu

Praktikum z molekulového modelingu

E-book

E-book

Ladislav Janovec

An enormous progress in computer technology, closely linked with advances in computational chemistry, has enabled the user to exploit the principles of quantum chemistry to elucidate the chemical phenomena.

Computational chemistry is the branch of science that requires, except an academic knowledge, software skills to fully exploit a potential of theoretical methods. The aim of this textbook is to help the user take the legendary first step in the field of computational chemistry to opening a new horizon of knowledge.

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Book of abstracts - New trends in chemistry, research and education 2019

Book of abstracts - New trends in chemistry,...

E-book

E-book

Zuzana Orságová Králová (ed.)

The scientific book of abstracts is a summary of the contributions of teachers, scientists and other conference participants, which contain the original results of their scientific and research activities. Their work will be the subject of the next domestic conference "New trends in chemistry, research and education 2019". The conference is a space for dialogue between scientific academics on the one hand and professional staff and students on the other.

The contributions published in this volume can be divided according to content into the field of analytical, inorganic, physical, organic chemistry, biochemistry and didactics of chemistry. All contributions are interesting and can be used in further creative scientific and research work, in the process of education and in practical work.

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Študentská vedecká konferencia PF UPJŠ 2019

Študentská vedecká konferencia PF UPJŠ 2019

E-book

E-book

Katarína Cechlárová (ed.)

This year, the Student Scientific Conference was held on April 24, 2019, across 17 sections in disciplines such as biology and ecology, chemistry, physics, geography, mathematics, informatics, and their didactics. Bachelor’s and master’s students presented a total of 124 contributions. The most successful participants advanced to national or traditional Czech-Slovak student scientific showcases in fields like physics, chemistry, mathematics, informatics, and mathematics didactics.

In addition to faculty students, 10 high school students participated outside the competition. They were invited based on their achievements in subject-specific Olympiads or because they were already engaged with the faculty under the guidance of dedicated teachers in laboratory work as part of their preparation for future studies. The day also featured a programming competition with 23 participants, an IHRA contest involving 16 teams of high school students and 15 teams from elementary schools, and a new Puzzle section where 72 high school students from the region competed.

The abstracts from the Student Scientific Conference demonstrate that our faculty's students not only absorb theoretical knowledge delivered in lectures but also actively engage in solving partial scientific problems that align with research objectives at the institutes of PF UPJŠ. This collection serves as both a record of scientific activity at the faculty and a dignified presentation for the broader public.

Prof. RNDr. Katarína Cechlárová, DrSc.

Vice-Dean for Education

Doc. RNDr. Gabriel Semanišin, PhD.

Dean of the Faculty

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Študentská vedecká konferencia PF UPJŠ 2018

Študentská vedecká konferencia PF UPJŠ 2018

E-book

E-book

Katarína Cechlárová (ed.)

In 2018, the Student Scientific Conference was held on April 18, 2018, in 16 sections covering biology and ecology, chemistry, physics, geography, mathematics, computer science, and their subject didactics. There were 110 registered contributions from bachelor's and master's students. Additionally, eight high school students participated outside of the competition; these students already visit our alma mater at a young age, work in our laboratories, and prepare for further studies under the guidance of our enthusiastic teachers. The day also included a programming competition and the IHRA competition in three categories, where students from PF UPJŠ competed alongside pupils from elementary and secondary schools.

The abstracts of the Student Scientific Conference contributions convincingly demonstrate that PF UPJŠ students study their field not only theoretically but also actively engage in solving partial scientific problems that are part of the research goals at PF UPJŠ institutes. This collection provides an overview of scientific activity at the faculty, which we believe will be interesting for the broader public as well.

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Študentská vedecká konferencia PF UPJŠ 2017

Študentská vedecká konferencia PF UPJŠ 2017

E-book

E-book

Katarína CechlárováEva Pitoňáková (eds.)

Proceedings of Abstracts from Contributions by Participants of the Student Scientific Conference at the Faculty of Science, UPJŠ in Košice, Held on April 26, 2017

This is the fifth edition of the proceedings from the Student Scientific Conference (ŠVK) at the Faculty of Science, Pavol Jozef Šafárik University in Košice. We are pleased that ŠVK has become an integral part of faculty life and a showcase for the quality of education provided. In 2017, ŠVK took place as part of the traditional Science Days on April 26, 2017. 105 students from the Faculty of Science presented their work. Contributions were organized into 15 sections, supplemented by an open programming competition involving 17 students and the final round of the IHRA competition, which included 27 teams from across Slovakia.

The abstracts in this proceedings demonstrate that students at the Faculty of Science, UPJŠ, acquire knowledge and skills in their field not only through theoretical study of disciplines but also through active engagement in solving partial scientific problems aligned with research goals at the faculty’s institutes. These abstracts also provide an overview of the faculty’s scientific activity, which we believe will be of interest to the broader public.

doc. RNDr. Gabriel Semanišin, PhD.

Dean of the Faculty

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Antioxidanty a ich význam v prevencii chronických ochorení

Antioxidanty a ich význam v prevencii...

E-book

E-book

Tatiana Kimáková - Vladimír Pavlík

The scientific monograph focuses on the characteristics of free radicals, reactive oxygen and nitrogen species, oxidative stress, and its impact on various diseases. A significant portion is dedicated to antioxidants, their classification based on multiple criteria, the characteristics of selected antioxidants in terms of their functions, manifestations of their deficiency and excess, and the overall antioxidant capacity of the body.

A special section is devoted to enzyme-based antioxidants, natural sources of antioxidants in the form of vitamins, trace elements, flavonoids, polyphenols, and coenzyme Q10. To provide a clearer understanding of antioxidants and their influence on population health, the monograph presents results from a research project included in the program "Research Support for Enhancing the Defense Capabilities of the Czech Republic in NATO Structures."

The research was conducted between 2010 and 2012 as part of preventive rehabilitation programs for professional soldiers with a sports component. The study involved 218 professional soldiers, including 180 men and 38 women, with an average age of 33.3 years. The current health status and dietary habits of the soldiers were assessed using questionnaires.

The study described the saturation of the observed group with antioxidant vitamins and statistically evaluated the relationship between their levels and the risk indicators for the development of cardiovascular diseases. Individual analyses were performed using the Reflotron device calibrated with Reflotron Precinorm control serum. Following blood collection, all participants underwent anthropometric examinations (body weight, height, waist circumference), blood pressure measurements, heart rate monitoring, and physical fitness assessments through simple functional tests.

This scientific monograph is suitable for the scientific community, students of medical, veterinary, and natural sciences, as well as public health students at all levels of university education. It is also intended for informed members of the public.

Authors

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Chemické výpočty vo všeobecnej a anorganickej chémii

Chemické výpočty vo všeobecnej a anorganickej...

E-book

E-book

Ivan Potočňák

The script is a study literature for the subject Chemical Calculations, which is a mandatory course in the bachelor's degree programs in Chemistry and Chemistry – Interdisciplinary Studies, first year. The script contains 10 chapters with a total of 207 pages, guiding students through solved and unsolved examples to help them understand the subject matter.

Author

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Ortuť v životnom prostredí ako rizikový faktor zdravia

Ortuť v životnom prostredí ako rizikový faktor...

E-book

E-book

Tatiana Kimáková

This scientific monograph is a comprehensive scientific work focused on the presence and effects of mercury in the environment, as well as the health risk factors associated with it.

The monograph presents a characterization of mercury in a multidisciplinary scope, discusses its use in industry and healthcare, and describes the negative impacts of mercury on the environment and public health. It also provides proposals and recommendations for at-risk groups. The monograph includes a comprehensive study of mercury concentration in samples of domestic and foreign production commodities and plant samples using the atomic absorption spectrometer AMA 254.

This scientific monograph is suitable for the scientific community, students of medical, veterinary, natural sciences, and agricultural fields, as well as public health students at all three levels of university study. It is also intended for all interested members of the informed public.

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Vybrané kapitoly z elektrochémie

Vybrané kapitoly z elektrochémie

E-book

E-book

Kveta Markušová - Daniela Kladeková

Electrochemistry is the science that studies ionic systems and the processes or phenomena that occur at the interface between ionic systems and metals or semiconductors. At the current stage of development, electrochemistry can be divided into two main areas based on its focus. The first one - ionics - deals with the properties of ionic systems (solutions, melts, solid electrolytes). The second area - electrodeics - focuses on phenomena at the electrode/ionic system interface.

Both ionics and electrodeics investigate equilibrium and non-equilibrium phenomena and processes. Research into the properties of ionic systems under equilibrium conditions provides information and insights into the structure and composition of electrolyte solutions, melts, and solid electrolytes, while measurements under non-equilibrium conditions provide data on the electrical conductivity of ionic systems. In the field of electrodeics, the study of equilibria at the electrode/solution (or melt) interface is the domain of electrochemical thermodynamics. Measuring the rates of processes occurring at this phase interface and explaining the principles governing these processes fall under the scope of electrode process kinetics or electrochemical kinetics.

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Študentská vedecká konferencia PF UPJŠ 2013

Študentská vedecká konferencia PF UPJŠ 2013

E-book

E-book

Vladimír Zeleňák (ed.)

The publication contains abstracts of contributions presented at the Student Scientific Conference of the Faculty of Natural Sciences at UPJŠ in Košice, held on April 25, 2013. The event was marked by the celebration of the 50th anniversary of the Faculty of Natural Sciences at UPJŠ and was part of a series of events called ScienceFest.

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Študentská vedecká konferencia PF UPJŠ 2016

Študentská vedecká konferencia PF UPJŠ 2016

E-book

E-book

Vladimír Zeleňák (ed.)

Proceedings of Abstracts of the Student Scientific Conference of the Faculty of Science, Pavol Jozef Šafárik University in Košice

A characteristic feature of education at high-quality universities — among which the Faculty of Science at Pavol Jozef Šafárik University (UPJŠ) in Košice proudly belongs — is the close connection between education and scientific research. Students gain knowledge in their field of study not only through theoretical coursework in individual disciplines, but also through active involvement in solving specific scientific tasks as part of research teams. This can occur during the development of final theses or through participation in the Student Research Assistant Program (ŠPVS), which was revitalized at the faculty in 2015.

The Student Scientific Conference (ŠVK) is one of the faculty’s traditional events, organized during the Faculty’s Science Days as part of Sciencefest. By its very nature, it fits seamlessly into the aforementioned framework of combining education with research, and it has long enjoyed great popularity and student interest. In 2016, the conference featured presentations by 125 students of the Faculty of Science at UPJŠ in Košice, across 16 thematic sections. This collection of abstracts provides an overview of the focus and goals of the student projects. We believe it will serve as inspiration for other potential participants of future conferences and will also be of interest to the broader public, offering additional insight into the faculty's activities.

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Študentská vedecká konferencia PF UPJŠ 2015

Študentská vedecká konferencia PF UPJŠ 2015

E-book

E-book

Vladimír Zeleňák(ed.)

The proceedings contain abstracts of contributions from participants of the Student Scientific Conference of the Faculty of Science, Pavol Jozef Šafárik University in Košice, which took place on April 22, 2015.

The Student Scientific Conference (SSC) enjoys long-term popularity among the faculty's students and teachers, and we are pleased that this was no different this year, with 128 contributions submitted to the SSC.

The contributions were organized into 19 sections, additionally complemented by an open programming competition and the final of the IHRA contest. For many students, presenting at the SSC is one of the first opportunities to gain experience in presenting their results before a professional audience. Considering the number of submitted contributions, along with the members of the expert juries from the faculty's teaching staff and the audience who came to support their classmates' presentations, the SSC is an event where a large part of the student and academic community of the faculty meets at one place and time. Many abstracts presented in this proceedings were developed as part of students' work on partial tasks that are components of research projects at the departments of the Faculty of Science, Pavol Jozef Šafárik University.

The abstracts represent, in a way, an overview of research topics at the individual workplaces of the faculty. The SSC proceedings thus serve as a useful tool that students and faculty teachers can use to present the faculty externally to partners, employers, and potential collaborators. Partners from practice have shown interest in cooperating in organizing the SSC for a long time. Since 2005, the association of IT companies has awarded a Prize for the Most Original Work and a Prize for the Work with the Best Prospects for Practical Application.

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Metodika tvorby učebných úloh a didaktických testov pre chémiu

Metodika tvorby učebných úloh a didaktických...

E-book

E-book

Mária Ganajová

The current teaching of chemistry has its specific problems. On one hand, due to the shift of the focus of chemistry curriculum towards theoretical content, the difficulty of chemistry material has increased, and in connection with this, students' interest in chemistry has decreased.

The lack of student interest in chemistry is mostly supported by the opinion that it is precisely chemistry that significantly contributes to the deterioration of environmental quality. On the other hand, we live in an era where we encounter chemical products practically everywhere. It is necessary to learn the basics of chemistry as well as possible, which makes the question of increasing interest in chemistry education and improving its effectiveness very relevant. State educational programs have been introduced into Slovak schools as a foundation for the creation of school educational programs. These emphasize not only acquiring a certain amount of knowledge but also the development and enhancement of key and specific competencies of students, preparing them for lifelong learning and their application in life.

Therefore, increasing attention is being paid to one of the fundamental didactic tools for raising student activity in teaching, and thus improving the effectiveness of chemistry education – learning tasks. From both theory and practice of chemistry teaching, we know that learning tasks, questions, examples, exercises, etc., are among the important components of every teaching lesson. Learning tasks are applied in all phases of teaching – in the motivational phase, the phase of acquiring knowledge, the phase of consolidating knowledge, and the phase of checking the acquired knowledge. It is therefore clear that every teacher will sooner or later find themselves in a situation where they will have to select learning tasks from textbooks, workbooks, collections of problems and examples, or create them themselves.

This scientific monograph is intended for educational specialists and chemistry teachers, aiming to familiarize them with examples of various types and forms of learning tasks and the basics of their creation in chemistry. It can also be helpful for them in preparing certification works focused on test creation and their statistical evaluation.

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50 rokov katedry organickej chémie

50 rokov katedry organickej chémie

E-book

E-book

Zuzana Kudličková(ed.)

Proceedings of Abstracts from the Scientific Conference with International Participation Organized on the Occasion of the 50th Anniversary of the Establishment of the Department of Organic Chemistry, Faculty of Science, Pavol Jozef Šafárik University in Košice, held on June 8–10, 2016 in Košice.

The Department of Organic Chemistry was established on February 1, 1966. From its inception, the department’s development prospects have been linked to high-quality scientific research focused on the synthesis of isothiocyanates and the products of their nucleophilic additions. In addition, studies were conducted on the use of cycloaddition, cyclocondensation, and photocyclization reactions of heterocumulenes in the synthesis of heterocycles.

Currently, research at the Department of Organic Chemistry is concentrated on stereoselective syntheses of iminosugars and γ-lactam-β-lactone antibiotics, total synthesis of natural compounds and their analogues possessing a sphingoid structure, research into the synthesis of indole alkaloids from the phytoalexin group, and the synthesis of acetylcholinesterase inhibitors based on acridine and coumarin derivatives.

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