Cvičenia z imunológie

E-book

Mária Vilková - Zuzana Kudličková - Aneta Salayová - Tomáš Ján Liška

The Nuclear Magnetic Resonance Practicum – Part 1: Quantitative NMR is designed for students taking the NMR Practicals course, which focuses on the practical aspects of quantitative nuclear magnetic resonance (qNMR). This publication builds on previous NMR courses and assumes basic theoretical knowledge of the method, emphasizing experimental procedures, data processing, and result interpretation. qNMR is a precise analytical technique with broad applications in analytical chemistry, pharmaceutical research, biomedicine, and quality control. The script provides a detailed guide to conducting experiments, as well as procedures for analyzing and evaluating acquired data. This publication offers students methodological guidance and support in mastering qNMR analysis and serves as a valuable resource not only during their studies but also for further research in NMR spectroscopy.

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Martin Bačkor - Miriam Bačkorová

The proposed text focuses on the history of studying biology, medicine, and pharmacy as scientific disciplines from prehistoric times through antiquity, the Middle Ages, and the modern era. The text chronologically organizes the most significant figures in the history of biological scientific disciplines, outlines key characteristics of major historical discoveries, and reevaluates their significance from the perspective of 21st-century science.

The educational text is chronologically divided into the most significant periods of civilization development. The last two completed centuries—the 19th and 20th—are subdivided into major life science fields due to the unprecedented growth of biological disciplines and the resulting volume of acquired information.

Since it can sometimes be challenging in science to define what constitutes the past versus the present of a particular discipline, we have excluded significant biological discoveries from the early 21st century, which are typically regarded as the “present” of biology.

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Jozef Strečka- Katarína Karl’ová (eds.)

Zborník obsahuje program a abstrakty workshopu s názvom: 1st Workshop on Perspective Electron Spin Systems for Future Quantum Technologies, ktorý sa bude konať 28.-29. júna 2022 v Košiciach. Workshop je organizovaný Prírodovedeckou fakultou Pavla Jozefa Šafárika v Košiciach a Ústavom experimentálnej fyziky Slovenskej akadémie vied v Košiciach s finančnou podporou Agentúry na podporu výskumu a vývoja. Ústrednými témami konferencie budú súčasné problémy kvantovej fyziky - kvantovej teórie magnetizmu spinových a elektrónových štruktúr, exotických kvantových spinových stavov, kvantového previazania, kvantových fázových prechodov, topologického kvantového počítania a kvantového spracovania informácie. Účastníci workshopu budú prezentovať originálne pôvodné výsledky svojho výskumu, ktoré môžu zásadným spôsobom ovplyvniť vývoj budúcich kvantových technológií.   

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Gabriela Andrejková - Ľubomír Antoni

Machine learning addresses the issues of how computer programs recognize complex patterns and make decisions based on data. In these university textbooks, we focus on theoretical knowledge in the field of machine learning in which we present the creation of concepts for objects, the preparation of concepts, hypotheses and the process of learning from examples. We describe Boolean formulas and their representations, probabilistic learning, linear and logistic regression, linear modeling and classification. Clustering and the Bayesian approach to machine learning conclude this publication.

University textbooks are intended for students of master's degree programs in computer science.

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Mária Kožurková

Tieto vysokoškolské učebné texty sú určené poslucháčom prvého ročníka magisterského štúdia na Prírodovedeckej fakulte UPJŠ v Košiciach. Rozsah a náplň prác zahrnutých v týchto skriptách vychádza hlavne z časových a priestorových možností s prihliadnutím na materiálovú náročnosť prác. Cieľom týchto skrípt je naučiť študentov základné mikrobiologické techniky a ukázať im význam mikroorganizmov v bežnom živote a ich dôležitú úlohu v prírode. Cvičenia sú zamerané tak, aby si študenti zvýšili svoju technickú zručnosť, naučili sa pracovať podľa bezpečnostných zásad. Text je rozdelený do 13 častí. V úvode každej z nich je uvedená teória k precvičovanej téme. V prílohe je návrh na vypracovanie protokolov k jednotlivým cvičeniam.

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Zuzana Vargová - Miroslav Almáši - Juraj Kuchár - Jana Dinajová 

The script „Základné laboratórne praktikum z anorganickej chémie“ builds on previous editions of the script, with some thematic units updated and supplemented with new knowledge, principles, and detailed work procedures.

This script is intended as a teaching aid for first-year students of the chemistry and interdisciplinary study programs at the Faculty of Science, Pavol Jozef Šafárik University in Košice. The introductory part of the volume acquaints students with safety regulations that they should follow during work in a chemical laboratory. Subsequently, in five chapters, basic laboratory techniques are described in detail, which students will use in the further part of the practices for preparing inorganic compounds. These chapters are enriched with illustrative images created using the freely distributable ACDFreeLabs 10 program or taken from literature listed at the end of the script. Some images were created by the authors, and others were taken from the catalog of Fisher Slovakia, s.r.o., which provided written permission for their use. The chapters describing the preparation of inorganic compounds are organized according to their composition, from simple elements or molecules, through binary compounds, acids, and salts, to complex compounds.

Within this subject, students should apply their theoretical knowledge gained during lectures on General Chemistry and Inorganic Chemistry and thereby acquire basic practical experience and skills that they will use in further studies.

The last two chapters were developed based on cooperation with Duslo a.s., Production Plant Strážske, which participates in the innovation of practical teaching through direct involvement of experts from practice as part of the KEGA project No. 008UPJŠ-4/2018.

Authors

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Erik Sedlák - Rastislav Varhač -  Patrik Danko - Helena Paulíková - Dušan Podhradský

The presented scripts were created in an effort to update and especially clarify the tasks that are solved in the basic practical exercises in biochemistry students of the 2nd and 3rd year of the bachelor's degree in chemistry, biology and their combinations with other disciplines. Most of the tasks come from the original scripts "Podhradský, Mihalovová: Praktické cvičenia z biochémie, Košice 1989".

Some of them have been modified to a greater or lesser extent and adapted to current conditions in the laboratory. New tasks were also added, such as those dedicated to nucleic acids. The scripts are thematically divided into six separate units, each of which consists of several tasks. The names of the units correspond to the nature of the biomacromolecules, which form their central theme. Theoretical introductions at the beginning of the unit are newly constructed and their main goal is to provide a brief overview of the basic biochemical methods used in the study of biomacromolecules.

These scripts are intentionally only available in electronic form. The reason is the effort to continuously update and modernize individual tasks according to the changing possibilities of our laboratory. We hope that the scripts will fulfill their role and that students will have sufficient theoretical knowledge and practical skills in the field of basic biochemical methods after completing these laboratory exercises.

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Ján Guniš - Ľubomír Šnajder

Prílohy

College scripts Programming in Python 1 are intended for future teachers of computer science. The content of the course is related to the teaching of programming in Scratch and is an introduction to text-based programming in Python.

Programming is introduced as a means of developing problem-solving skills. The first chapter is devoted to problem solving. The next 12 chapters sequentially introduce basic language constructions, data structures, and selected types of algorithms. Each of these chapters begins with an introduction to the problem. This section is primarily intended for self-study, to prepare students for the exercises. The following subchapter summarizes and completes the knowledge, and additional insights and approaches related to the chapter topic are presented. The chapters include a collection of exercises designed to practice and deepen knowledge and skills on the topic.

The final part of the chapter presents the solved problems. This section serves as a guide to solving the problems in the collection.

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Gregor Bánó

Photonics is an application-oriented discipline at the interface of optics, opto-electronics and quantum optics. It includes classical optics extended by the description of physical phenomena and optical devices that rely on quantum (photon) nature of light.
The main objective of the Photonics course is to provide a comprehensive overview of essential optical and photonic phenomena routinely applied in experimental scientific research while working with various light sources (e.g. in the field of biophotonics). The first chapters are devoted to the description of light at different levels. The logical order of subsections in this part corresponds to the structure of the textbook: B. E. A. Saleh, M. C. Teich, Fundamentals of Photonics. The following chapters contain a description of laser operation and an overview of selected optical instruments and their applications.
The body text is complemented by practical notes on the use of theoretical knowledge during daily work in the laboratory. The course of Photonics requires a basic knowledge of mathematics, electromagnetism and optics, and thus it is recommended to students who previously passed through the courses of the Bachelor's program in Physics.

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Monika Tvrdoňová, Miroslava Martinková

The scientific book of abstracts from conference „Novel Trends in Chemistry, Research and Education 2022“ is a summary of the contributions of conference participants, which contain the original results of their scientific and research activities. The contributions published in this volume can be divided according to content into the field of analytical, inorganic, organic, physical chemistry, biochemistry, didactics of chemistry and NMR spectroscopy.

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Mária Reháková 

Vysokoškolský učebný text určený pre poslucháčov vyšších ročníkov z bioanorganickej chémie. Štúdium bioanorganickej chémie si vyžaduje vedomosti z predchádzajúcich chemický disciplín nižších ročníkov - všeobecnej, anorganickej, organickej, fyzikálnej chémie a biochémie.

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E-book

Božena Mihalíková - Ján Ohriska

Tento učebný text je určený poslucháčom prvého ročníka študijného odboru 76–12–8 „Učiteľstvo všeobecnovzdelávacích predmetov“ v kombináciách s matematikou. Je vyhotovený na základe prednášok autorov a ich viac ako desaťročných skúseností z výučby tohoto predmetu na PF UPJŠ. Pri jeho písaní sa autori snažili zohľadniť špecifickosť učiteľského štúdia matematiky. Predkladaný učebný text nebol písaný pre nedostatok učebníc matematickej analýzy. Dôvodom pre jeho napísanie boli zistenia autorov, že poslucháči nemajú zo strednej školy dostatočné skúsenosti v práci s odbornou literatúrou, ťažkosti mnohým spôsobuje (najmä v prvých semestroch) čo i len trochu odlišný výklad, nie zriedka aj zmena v označovaní, čím im uniká podstata študovanej problematiky. Autori textu si nekládli za ciel byt originálni. Ich snahou bolo urobiť taký výber tém, aký je nutný pre budúceho učiteľa matematiky a zvoliť takú metódu výkladu, ktorá je podla ich názoru vhodná pre poslucháčov prvého ročníka. Dobré zvládnutie učiva (rozšírenie matematického aparátu a s tým súvisiace možnosti uplatnenia iných dokazovacích metód ako aj získanie potrebných početných schopností) predpokladá použitie aj ďalších literárnych prameňov (učebníc, zbierok úloh) podla odporúčania vyučujúceho.

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Terézia Kisková - Stanislav Matéffy - Františka Horváthová

The laboratory rat (Rattus norvegicus) is one of the most commonly used experimental animals. It serves as a model organism for analyzing numerous biological processes and pathological mechanisms, such as cardiovascular diseases, metabolic disorders (e.g., lipid metabolism, diabetes mellitus), neurological and neuropsychiatric conditions (e.g., stroke, epilepsy, or Alzheimer's disease), neurobehavioral research, autoimmune diseases (e.g., arthritis), cancer, and renal diseases. It offers many unique advantages for modeling human diseases, testing drugs and natural substances, and studying responses to environmental factors. The size of the laboratory rat, compared to the mouse, creates ideal conditions for physiological manipulations. Additionally, rats are used in clinical toxicology to test chemical substances (Hedrich, 2000).

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Jozef Strečka

The present textbook deals with exactly solved models and their diverse applications in several branches of physics such as mathematical physics, statistical physics, condensed matter physics and so on. Exactly soluble models are currently considered as an inspiring research field in its own right, which regrettably requires a considerable knowledge of sophisticated mathematics. Accordingly, my primary ambition was to provide an intro- ductory course for undergraduate students that would cover the simplest exactly solved models, whose rigorous solutions are available even after modest calculation. The present textbook should be therefore regarded as an auxiliary graduate-level textbook, which should serve as the student’s guide on this beautiful but surely intricate subject.

Even although I attempted to write largely self-contained textbook for undergraduate students, it is worthy of notice that the course on Exactly Solvable Models in Statistical Physics demands essential knowledges from the quantum mechanics, statistical physics, phase transitions and critical phenomena, which are its indispensable prerequisities. The most crucial fundamentals of these theories are briefly recalled in introductory remarks just for remembering and not for substituting those comprehensive courses. The rest of this textbook is entirely devoted to exactly solved lattice-statistical models with the main emphasis laid on their possible applications in the condensed matter physics. It is the author’s hope that the presented exact solutions are detailed enough in order to be easily followed by undergraduate students even without a support of tedious proofs, cumbersome theorems, longer argumentations, or obvious facts. This rather necessary compromise has of course a certain unadvisable impact on ’exactness’ of the presented solutions.

Finally, it is worthwhile to remark that the present textbook makes just a slight introduction into the simplest exactly solvable models and thus, the interested reader is referred for the follow-up study to several excellent books on exactly solved models quoted in the bibliography list on the next page. Note that the listed books were the major knowledge sources used by creating this textbook and they might be regarded as more advanced literature on this exciting research field.

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Daniela Kladeková

Práca s učebným textom predpokladá primerané znalosti z oblasti fyzikálnej chémie, fyziky a biológie, bez ktorých je orientácia v predkladanom študijnom materiáli zložitá. Solídne znalosti z matematiky sú nevyhnutné a pomáhajú pri pochopení problémov koloidnej chémie. V skriptách, ktoré sa členia na jednotlivé kapitoly, po klasifikácii a charakterizácii disperzných sústav sa najprv rozoberajú optické a molekulovo-kinetické vlastnosti. 
Mimoriadne veľký medzifázový povrch, ktorý je charakteristický hlavne pre koloidne disperzné sústavy, pripisuje zvlášť dôležitú úlohu javom, ktoré prebiehajú na fázovom rozhraní, t.j. povrchovým javom. V súvislosti s týmto poznatkom diskutujú sa vlastnosti mobilných fázových rozhraní a fázového rozhrania tuhá látka/plyn a tuhá látka/kvapalina. Významná je následne zaradená kapitola o elektrických vlastnostiach disperzných sústav. Táto kapitola je tesne spojená s otázkami vzniku, štruktúry, stability a deštrukcie disperzií; pozornosť sa venuje predovšetkým koloidným sústavám. Neoddeliteľnou súčasťou je aj kapitola, ktorá popisuje reologické vlastnosti disperzných sústav. Ďalšie kapitoly uvádzajú jednotlivé typy disperzných sústav.

Tento vysokoškolský učebný text je určený najmä študentom chemických a ekologických odborov na Prírodovedeckej fakulte Univerzity P. J. Šafárika v Košiciach. Nekladie si za cieľ vyčerpávajúco rozoberať do detailov celú problematiku, lebo o nej pojednávajú monografie nielen z koloidnej a makromolekulovej chémie, často možno nájsť detailné rozpracovanie aj v základných učebniciach fyzikálnej chémie.

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Tatiana Kimáková

Táto vedecká monografia je komplexnou vedeckou prácou zameranou na prítomnosť a pôsobenie ortuti v životnom prostredí, ale aj na rizikové faktory zdravia, ktoré sú s ňou spojené. Monografia predstavuje charakteristiku ortuti v multidisciplinárnom zábere, prezentuje využitie v priemysle a v zdravotníctve, popisuje negatívne vplyvy ortuti v životnom prostredí, na zdravotný stav obyvateľstva. Zároveň prináša návrhy a odporúčania pre rizikové skupiny ľudí. Súčasťou monografie je komplexný výskum koncentrácie ortuti vo vzorkách komodít domácej i zahraničnej produkcie a vo vzorkách rastlín pomocou atómového absorpčného spektrometra AMA 254. Vedecká monografia je vhodná pre vedeckú komunitu, študentov medicínskych, veterinárnych, prírodovedných a poľnohospodárskych odborov ako aj pre študentov verejného zdravotníctva všetkých troch stupňov vysokoškolského štúdia. Monografia je učená aj pre všetkých záujemcov z radov informovanej verejnosti.

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