Vybrané úlohy a výpočty z biochémie – metabolizmus

E-book

Mária Vilková - Zuzana Kudličková - Aneta Salayová - Tomáš Ján Liška

The Nuclear Magnetic Resonance Practicum – Part 1: Quantitative NMR is designed for students taking the NMR Practicals course, which focuses on the practical aspects of quantitative nuclear magnetic resonance (qNMR). This publication builds on previous NMR courses and assumes basic theoretical knowledge of the method, emphasizing experimental procedures, data processing, and result interpretation. qNMR is a precise analytical technique with broad applications in analytical chemistry, pharmaceutical research, biomedicine, and quality control. The script provides a detailed guide to conducting experiments, as well as procedures for analyzing and evaluating acquired data. This publication offers students methodological guidance and support in mastering qNMR analysis and serves as a valuable resource not only during their studies but also for further research in NMR spectroscopy.

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E-book

Peter Fedoročko (ed.)

Proceedings of the 7th Annual Doctoral Spring School 2020

From November 10 to November 11, 2020, the 7th annual Spring School for Doctoral Students at Pavol Jozef Šafárik University in Košice will take place in Košice in a modified mode in the on-line space. The scientific program of the spring school will comprise 2 plenary lectures by leading scientific experts of Pavol Jozef Šafárik University in Košice. Doctoral students will present their research papers in two sections: 24 doctoral students of Faculty of Public Administration, Faculty of Law and Faculty of Arts, and 22 doctoral students of Faculty of Medicine and Faculty of Science.

The scientific programme of the spring school will also include a panel discussion with the management of Pavol Jozef Šafárik University in Košice.

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 Andrej Oriňak - Renáta Oriňaková - Andrea Fedorková

Nanotechnology represent the fastest developing science in the present. They are based on the technologies that enable the matter manipulation at atomic level. Nanotechnology offer prepartion of the new materials with unknown and very specific properties and functions.Recent nanotechnology still stay in formative phase of their development. But more and more they are visible with nano-specific phenomenons in the fundamental control of the properties as well mater behaviour. This is quite possible that without nanotechnology will not work any science to the future, moreover that science will not exist anymore. Nanotechnolgy will give a chance and force to transform world to more environmental and comfortable. Expected is expansion of the nanotechnolgy to molecular nanosystems – heterogenous nets, in which molecules and supramolecules work as the nanodevices. The computers and robots will be reduced to the small and ultrasmall dimensions. In medicine will foremost the application of nanotechnology in genetic therapy and elimination of ageing. Nanosurgery will work at molecular level, cancer cells will be identified early and filtered , then substituted with healthy and unchanged. It is necessary to inform university or high school students  about principles of nanotechnolgy, preparation of the nanostructures, functionality of them and to offer full representation about molecular systems and nanodevices; the methods of nanostructures characterization and about application in miniaturized systems. 

Authors

E-book

Miroslava Martinková

This electronic material focuses on the subject of secondary metabolism and its products - secondary metabolites. The material gives an overview of the basic building blocks and construction mechanisms through which molecules can be synthesized in living organisms (plants). The processes of formation of the mentioned metabolites are explained using the basic mechanisms of organic reactions. Several of the secondary metabolites presented have a remarkable biological profile and are used as therapeutics or serve as lead compounds for the development of novel pharmacological agents. This electronic document is primarily intended for students of the Master's degree programme in Organic Chemistry as supporting material for the profile subject Chemistry of Natural Products.

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Matúš Harminc

Učebný text je určený poslucháčom medziodborového štúdia v kombinácii s matematikou, jednoodborového štúdia matematiky ako aj rozširujúceho štúdia matematiky. Je zameraný na základné poznatky o deliteľnosti celých čísel, kongruenciách a aritmetických funkciách.

Autor

E-book

Valéria Skřivánková - Martina Hančová

The publication is focused on discrete random processes, primarily on Markov chains, which have wide application in the field of economics and finance.

The textbook is divided into five chapters, the first of which serves as an introduction to random processes and provides definition, properties and classification of random processes in general. The second chapter discusses Markov chains with discrete time, including valuation of transitions between states and their optimal management. The third chapter focuses on special Markov chains with continuous time and emphasizes construction and solution to the system of Kolmogorov differential equations, which describe the dynamics of the process development. The last two chapters illustrate applications of Markov chains using examples of queuing system modeling and renewal theory.

Besides the explanation of basic terms, definitions and theorems with proofs, this textbook also provides number of solved examples to illustrate the discussed theory. Problem assignments are placed at the end of each chapter, so that readers can test their understanding of the content as they progress through the book. Solutions to all the problems and the list of references are provided at the end of the publication.

This textbook is primarily intented for students majoring in Economics and Financial Mathematics at the Faculty of Science of Pavol Jozef Šafárik University in Košice, and it covers content of the course “Random Proceses 1“ thought there. It might however serve also students from other schools in similar progams or professionals interested in this topic.

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E-book

Daniel Klein

Statistics is defined as a scientific discipline based on learning from data and on finding, controlling, and presenting uncertainty. In these university textbooks we present the history of statistics, basic concepts of statistical modeling, measurement of dependencies, regression models, analysis of variance. We describe simple sorting, multiple comparisons, assumptions of the ANOVA model, Kruskal-Wallis test.

University textbooks are suitable for students of mathematics and computer science at the first and second level of universities. Study materials are also suitable for students of non-informatics disciplines with a view to improving their knowledge and practical experience in the fields of informatics and provide an opportunity for students to apply in IT companies in solving practical tasks.

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E-book

Gabriel Semanišin - Emil Hutňan - Jana Oleničová

The proceedings contain abstracts of contributions from participants of the UNIFOS 2014 conference, University Information Systems in Košice, which took place from October 27 to 29, 2014.

ICT centers are important element that provide functioning and development hardware and software infrastructure at Slovak Universities. There are more differences between them in real position, management, personal sources and financing. ICT centers provide a wide range of services to large number of university users and they implement the policy of information security recently.

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Peter Kollár a kol. 

Skriptá Základné fyzikálne praktikum II. sú určené pre študentov Prírodovedeckej fakulty UPJŠ v Košiciach študujúcich na študijných programoch fyzika a medziodborových programoch v kombinácii s fyzikou. Obsahom skrípt sú úlohy z elektriny, magnetizmu a optiky. Podľa študijných programov sú zaradené do 3.semestra bakalárskeho štúdia, v ktorom by už študenti mali mať absolvovaný predmet všeobecná fyzika II. (elektrina a magnetizmus). Súčasťou každej úlohy sú základné poznatky venované javom, ktoré sú obsahom samotnej úlohy.

Autori

E-book

Vladimír Sedlák

The university textbooks entitled Global Navigation Satellite Systems: GPS, GLONAS, Galileo, Compass present four navigation systems of the GNSS (Global Navigation Satellite Systems): American NAVSTAR GPS, Russian GLONASS, European Galileo and Chinese Compass. The Satellite-Based Augmentation Systems (SBAS) are also briefly explained. They provide regional service in augmenting the reach and support of signals from satellites of the GNSS (GPS, GLONASS, Galileo, Compass). Each satellite navigation system in the frame of GNSS is elucidated in terms of its principles of operation, structure, specificities, applications, and future perspectives.

The university textbook aims to improve the reader’s understanding of the principles and activities of the presented GNSS. The book emphasizes the possibilities of GNSS applications in geodesy and geography. The university textbook constitutes the basic study literature for the class Global Navigation Satellite Systems within the study program Geography and Geoinformatics at the Faculty of Science of the Pavol Jozef Šafárik University in Košice. For a deeper study of the GNSS issue, it is necessary to extend the study materials to include other educational scientific literature dealing with navigation satellite systems and their applications.

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E-book

Terézia Kisková - Stanislav Matéffy - Františka Horváthová

The laboratory rat (Rattus norvegicus) is one of the most commonly used experimental animals. It serves as a model organism for analyzing numerous biological processes and pathological mechanisms, such as cardiovascular diseases, metabolic disorders (e.g., lipid metabolism, diabetes mellitus), neurological and neuropsychiatric conditions (e.g., stroke, epilepsy, or Alzheimer's disease), neurobehavioral research, autoimmune diseases (e.g., arthritis), cancer, and renal diseases. It offers many unique advantages for modeling human diseases, testing drugs and natural substances, and studying responses to environmental factors. The size of the laboratory rat, compared to the mouse, creates ideal conditions for physiological manipulations. Additionally, rats are used in clinical toxicology to test chemical substances (Hedrich, 2000).

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Danica Studenovská - Tomáš Madaras 

Táto publikácia je určená pre študentov nematematických odborov na Prírodovedeckej fakulte UPJŠ v Košiciach. Jej obsahom je látka preberaná v prvom semestri v rámci predmetu Matematika I..

Publikácia nadväzuje na učivo stredných škôl a nevyžaduje žiadne predbežné špeciálne znalosti. Môže slúžiť ako základ na ďalšie samostatné štúdium a môže byť užitočná aj pre iných záujemcov o matematiku a jej aplikácie.

Vyriešené príklady v jednotlivých kapitolách majú pomôcť čitateľovi pri zvládnutí štúdia. Tomu napomáhajú aj ilustratívne obrázky.

Autori

E-book

Ján Füzer

Auxiliary teaching material for the course General Physics III – Oscillations, Waves, and Optics is intended for students of single-subject and interdisciplinary studies of physics.

The content provides a basic outline of the material covered, without detailed explanations, with an emphasis on the physical method of thinking using the simplest elements of higher mathematics. The presented text does not aim to replace the recommended textbooks, but rather to help students navigate the subject matter. Recommended literature can be found at the end of the text.

The teaching material contains the basic framework of the lectures and is supplemented and revised each year, with lectures enriched by supporting demonstration experiments.

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E-book

Danica Sabolová

This university textbook is intended for students of the Faculty of Science of the University of Applied Sciences in Košice who have enrolled in practical exercises in Biotechnology, but also for all other students who are interested in learning about the practical applications of biotechnology.

The aim of the practical course is to familiarize students with basic biotechnological methods and their applications. The students will verify in practice the theoretical knowledge acquired in the Biotechnology lectures such as the course of fermentation processes, wine production, preparation of fermented milk products and cheese, preparation of culture media, inoculation and cultivation of microorganisms, etc. The practical exercises also include the use of analytical and spectral methods, which are an integral part of biochemistry.

The scripts are published only in electronic form and are available on the University's website: http://kosice.upjs.sk/~kbch/sk, for the reason that it will always be possible to update and modernize the content of the laboratory exercises.

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E-book

Stanislav Lukáč - Ľubomír Šnajder - Ján Guniš - Zuzana Ješková

The publication is intended for researchers in didactics and teachers of mathematics and computer science. Our aim is to provide readers with a basic orientation in the issue of inquiry-based teaching, to explain and demonstrate several levels of student inquiry through examples, and to offer a classification of inquiry skills.

The core part of the publication consists of methodologies for inquiry-based teaching of specific topics from school mathematics and computer science. We present ideas for implementing inquiry activities, active work with information in solving various types of problems, and the application of modern digital technologies in exploring and discovering patterns.

The publication includes seven methodologies for teaching mathematics and eight methodologies for teaching computer science in the 1st and 2nd years of secondary school.

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Prílohy

E-book

Vladimír Zeleňák (ed.)

Proceedings of Abstracts of the Student Scientific Conference of the Faculty of Science, Pavol Jozef Šafárik University in Košice

A characteristic feature of education at high-quality universities — among which the Faculty of Science at Pavol Jozef Šafárik University (UPJŠ) in Košice proudly belongs — is the close connection between education and scientific research. Students gain knowledge in their field of study not only through theoretical coursework in individual disciplines, but also through active involvement in solving specific scientific tasks as part of research teams. This can occur during the development of final theses or through participation in the Student Research Assistant Program (ŠPVS), which was revitalized at the faculty in 2015.

The Student Scientific Conference (ŠVK) is one of the faculty’s traditional events, organized during the Faculty’s Science Days as part of Sciencefest. By its very nature, it fits seamlessly into the aforementioned framework of combining education with research, and it has long enjoyed great popularity and student interest. In 2016, the conference featured presentations by 125 students of the Faculty of Science at UPJŠ in Košice, across 16 thematic sections. This collection of abstracts provides an overview of the focus and goals of the student projects. We believe it will serve as inspiration for other potential participants of future conferences and will also be of interest to the broader public, offering additional insight into the faculty's activities.

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E-book

Mária Vilková - Zuzana Kudličková - Aneta Salayová - Tomáš Ján Liška

The Nuclear Magnetic Resonance Practicum – Part 1: Quantitative NMR is designed for students taking the NMR Practicals course, which focuses on the practical aspects of quantitative nuclear magnetic resonance (qNMR). This publication builds on previous NMR courses and assumes basic theoretical knowledge of the method, emphasizing experimental procedures, data processing, and result interpretation. qNMR is a precise analytical technique with broad applications in analytical chemistry, pharmaceutical research, biomedicine, and quality control. The script provides a detailed guide to conducting experiments, as well as procedures for analyzing and evaluating acquired data. This publication offers students methodological guidance and support in mastering qNMR analysis and serves as a valuable resource not only during their studies but also for further research in NMR spectroscopy.

Download the e-book for free (pdf)

E-book

Peter Fedoročko (ed.)

Proceedings of the 7th Annual Doctoral Spring School 2020

From November 10 to November 11, 2020, the 7th annual Spring School for Doctoral Students at Pavol Jozef Šafárik University in Košice will take place in Košice in a modified mode in the on-line space. The scientific program of the spring school will comprise 2 plenary lectures by leading scientific experts of Pavol Jozef Šafárik University in Košice. Doctoral students will present their research papers in two sections: 24 doctoral students of Faculty of Public Administration, Faculty of Law and Faculty of Arts, and 22 doctoral students of Faculty of Medicine and Faculty of Science.

The scientific programme of the spring school will also include a panel discussion with the management of Pavol Jozef Šafárik University in Košice.

Download the e-book for free  (pdf)

 Andrej Oriňak - Renáta Oriňaková - Andrea Fedorková

Nanotechnology represent the fastest developing science in the present. They are based on the technologies that enable the matter manipulation at atomic level. Nanotechnology offer prepartion of the new materials with unknown and very specific properties and functions.Recent nanotechnology still stay in formative phase of their development. But more and more they are visible with nano-specific phenomenons in the fundamental control of the properties as well mater behaviour. This is quite possible that without nanotechnology will not work any science to the future, moreover that science will not exist anymore. Nanotechnolgy will give a chance and force to transform world to more environmental and comfortable. Expected is expansion of the nanotechnolgy to molecular nanosystems – heterogenous nets, in which molecules and supramolecules work as the nanodevices. The computers and robots will be reduced to the small and ultrasmall dimensions. In medicine will foremost the application of nanotechnology in genetic therapy and elimination of ageing. Nanosurgery will work at molecular level, cancer cells will be identified early and filtered , then substituted with healthy and unchanged. It is necessary to inform university or high school students  about principles of nanotechnolgy, preparation of the nanostructures, functionality of them and to offer full representation about molecular systems and nanodevices; the methods of nanostructures characterization and about application in miniaturized systems. 

Authors

E-book

Miroslava Martinková

This electronic material focuses on the subject of secondary metabolism and its products - secondary metabolites. The material gives an overview of the basic building blocks and construction mechanisms through which molecules can be synthesized in living organisms (plants). The processes of formation of the mentioned metabolites are explained using the basic mechanisms of organic reactions. Several of the secondary metabolites presented have a remarkable biological profile and are used as therapeutics or serve as lead compounds for the development of novel pharmacological agents. This electronic document is primarily intended for students of the Master's degree programme in Organic Chemistry as supporting material for the profile subject Chemistry of Natural Products.

Download e-book for free (pdf)

Matúš Harminc

Učebný text je určený poslucháčom medziodborového štúdia v kombinácii s matematikou, jednoodborového štúdia matematiky ako aj rozširujúceho štúdia matematiky. Je zameraný na základné poznatky o deliteľnosti celých čísel, kongruenciách a aritmetických funkciách.

Autor