BIOLÓGIA LIŠAJNÍKOV. Časť C: Identifikácia metabolitov pomocou NMR spektroskopie

E-book

Martin Bačkor - Miriam Bačkorová

The proposed text focuses on the history of studying biology, medicine, and pharmacy as scientific disciplines from prehistoric times through antiquity, the Middle Ages, and the modern era. The text chronologically organizes the most significant figures in the history of biological scientific disciplines, outlines key characteristics of major historical discoveries, and reevaluates their significance from the perspective of 21st-century science.

The educational text is chronologically divided into the most significant periods of civilization development. The last two completed centuries—the 19th and 20th—are subdivided into major life science fields due to the unprecedented growth of biological disciplines and the resulting volume of acquired information.

Since it can sometimes be challenging in science to define what constitutes the past versus the present of a particular discipline, we have excluded significant biological discoveries from the early 21st century, which are typically regarded as the “present” of biology.

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E-book

Vladislav Kolarčik

Flow cytometry is a diagnostic and research technique that enables rapid analysis of cells, nuclei and organelles of plants and other organisms. In plant biology, it is most often used for DNA content analysis in a wide range of applications. It is the method of first choice and its importance is even increasing compared to competing technologies. It is unrivaled in speed, accuracy, repeatability and low cost. Flow cytometry has become a standard tool in laboratories focused on biological-ecological plant research.

This textbook provides information on the historical development of flow cytometry and its establishment in the analysis of the plant genome. It describes the procedure of sample analysis to determine the nuclear DNA content and presents the basic applications, such as determination of genome size, ploidy level and reproduction modes of plants and determination of endopolyploidy level in plant tissues. These college textbooks are intended for students, teachers and anyone interested in the use of flow cytometry in scientific work with plant cells.

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Norbert Kopčo - Frederick Gallun - Beáta Tomoriová - Ľuboš Hládek(eds.)

Cognitive neuroscience is a fast developing scientific field which aims at uncovering the neural basis of human perception and cognition. To achieve this goal, cognitive neuroscience uses a variety of tools and approaches ranging from non-invasive brain imaging to psychophysics and neural modeling. Mastering such tools requires skills and knowledge from multiple scientific domains, including neurophysiology, cognitive psychology, and several computational fields.

Access on request via email: kogneuro (@) gmail.com

http://pcl.upjs.sk/workshopcd 

https://sites.google.com/site/kogneuro/

E-book

Kveta Markušová - Daniela Kladeková

Electrochemistry is the science that studies ionic systems and the processes or phenomena that occur at the interface between ionic systems and metals or semiconductors. At the current stage of development, electrochemistry can be divided into two main areas based on its focus. The first one - ionics - deals with the properties of ionic systems (solutions, melts, solid electrolytes). The second area - electrodeics - focuses on phenomena at the electrode/ionic system interface.

Both ionics and electrodeics investigate equilibrium and non-equilibrium phenomena and processes. Research into the properties of ionic systems under equilibrium conditions provides information and insights into the structure and composition of electrolyte solutions, melts, and solid electrolytes, while measurements under non-equilibrium conditions provide data on the electrical conductivity of ionic systems. In the field of electrodeics, the study of equilibria at the electrode/solution (or melt) interface is the domain of electrochemical thermodynamics. Measuring the rates of processes occurring at this phase interface and explaining the principles governing these processes fall under the scope of electrode process kinetics or electrochemical kinetics.

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E-book

Vladimír Komanický

The aim of this textbook is to acquaint students in physics, chemistry and material science on both undergraduate and graduate level, with the techniques used to prepare micro-electromechanical devices, nanoobjects and nanostructures using the so called top down methodologies. The is no requirement for this course to pass any prior courses. The introduction part of the text defines the forces that affect nanoobjects and the interactions between them. Reader can understand in detail why properties of nanomaterials and nanostructures are so different when comprared to their macroscopic counterparts. Text gives also an overview of thin film preparation technologies as precursors for the preparation of nanostructures. The main emphasis in Volume I is on conventional lithographic technologies for the preparation and shaping of nanostructures, methods for characterization of thin films, nanoparticles and nanomaterials. Unconventional lithographic methods will also be discussed in the prepared upcoming Volume II. Student will also get acquainted with the applications of nanostructures in research focused on nanophysics, nanocatalysis and nanoelectronics. The textbook is used as a study material for the course ÚFV / MPN / 14 - Methods of preparation and characterization of nanostructures. Part of the course is also a laboratory exercise in which the student gets acquainted with the techiques used for the preparation and characterization of thin films and top-down technologies used for the preparation of nanostructures.

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E-publication

Denisa Maceková-Monika Václavková-Marek Kvet-Ivana Sotáková

The publication Digiform: A Supporting Application to Digilib – User Guide, Part B presents the Digiform web application as a tool that extends the functionality of the Digilib digital library of formative assessment tools. The application enables the creation and editing of formative assessment tool templates, which can be adapted to the specificities of individual subjects and levels of education and subsequently imported into the Digilib environment for use in the teaching process. The guide provides a detailed description of how to work with the Digiform application, from creating new templates, editing and personalising them, through to their export and implementation in the main Digilib application. Attention is also given to the interconnection with the Digilib Images application, which enables the integration of visual elements into the assessment tools, thereby enhancing their didactic effectiveness and visual appeal. The guide is intended for teachers at all levels of education, student teachers, school administrators, and digital coordinators who are interested in the systematic use of the Digilib digital library to support the implementation of formative assessment, enhance the quality of the educational process, and foster the development of students’ self-assessment and reflective competences.

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E-book

Andrea Morovská Turoňová

The discovery of radioactivity at the turn of the 19th and 20th centuries stimulated the rapid development of nuclear sciences. At the interface between nuclear physics and chemistry, disciplines such as radiochemistry, radiation chemistry and nuclear chemistry were formed.

The aim of the Nuclear Chemistry course which is taught at the PF UPJŠ is to provide basic knowledge, with an emphasis on the general value of the subject. It is important to make available the basics of various methods, techniques and their specifics in the application of nuclear phenomena in chemistry and related fields. Emphasis is also placed on the use of correct terminology, knowledge of the context of relationships and basic principles, supplemented by illustrative concrete cases.

The choice of material is rather difficult, but we count on additional monographs and textbooks to fill in the gaps of these teaching texts.

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E-book

Marek Bombara

The collection of exercises summarises and supplements the exercises realised at the Pavol Jozef Šafárik in Košice within the lecture course Elementary Particle Physics. The collection is intended for the master students of the Nuclear and Subnuclear Physics subject, but it could be beneficial also for other physics subjects or even for interdisciplinary study. 

The division of chapters roughly copies the order of lectures. At the beginning, students will briefly familiarize themselves with the basics of special relativity and its practical use in particle physics.

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E-publication

Beáta Valkay ed.
Ivana Slepáková-Monika Balogová a kol.

EFFUSE - Scientific Education for Advanced is an educational material designed for university students interested in ecological sciences, biology and environmental protection. The publication was developed as part of the EFFUSE project and focuses on the scientific investigation of living organisms in the river ecosystem, with an emphasis on their ecological role and importance as bioindicators. The river ecosystem is a dynamic environment where a wide range of organisms can be studied, from algae and phytoplankton to aquatic invertebrates, fish, amphibians and reptiles. This publication presents a detailed study of their adaptations, life cycles, reproductive strategies and their importance for ecological balance. Particular attention is paid to fish and amphibians, whose environmental demands and sensitivity to pollution make them important indicators of water quality and environmental status. The publication also provides guidance on how to integrate their study into university education in the form of practical research. It also includes a chapter on science education in the context of sustainable development, which is often absent from university curricula in Slovakia and Ukraine. This material promotes the link between theory and practice and develops students' scientific thinking in order to prepare them to meet the environmental challenges of the future.

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E-book

Terézia Kisková - Stanislav Matéffy - Františka Horváthová

The laboratory rat (Rattus norvegicus) is one of the most commonly used experimental animals. It serves as a model organism for analyzing numerous biological processes and pathological mechanisms, such as cardiovascular diseases, metabolic disorders (e.g., lipid metabolism, diabetes mellitus), neurological and neuropsychiatric conditions (e.g., stroke, epilepsy, or Alzheimer's disease), neurobehavioral research, autoimmune diseases (e.g., arthritis), cancer, and renal diseases. It offers many unique advantages for modeling human diseases, testing drugs and natural substances, and studying responses to environmental factors. The size of the laboratory rat, compared to the mouse, creates ideal conditions for physiological manipulations. Additionally, rats are used in clinical toxicology to test chemical substances (Hedrich, 2000).

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Mária Reháková 

Vysokoškolský učebný text určený pre poslucháčov vyšších ročníkov z bioanorganickej chémie. Štúdium bioanorganickej chémie si vyžaduje vedomosti z predchádzajúcich chemický disciplín nižších ročníkov - všeobecnej, anorganickej, organickej, fyzikálnej chémie a biochémie.

Autorka

E-book

Miroslav Repčák - Martin Bačkor - Peter Paľove-Balang - Silvia Gajdošová

The establishment of the Plant Physiology Laboratory at the Department of Botany, Faculty of Arts, Pavol Jozef Šafárik University in Košice in 1969 was associated with the name of Ing. Štefan Kocúrik, CSc. (1923–2006), who also prepared the first "Instructions for Exercises in Plant Physiology" (Košice 1972, 1976).

Since 1980, the manual by Associate Professor RNDr. Karol Erdelský, CSc., and Ing. Fridrich Frič, DrSc., titled "Practicum and Analytical Methods in Plant Physiology" (Bratislava 1980) has been used. With the increase in the number of students, it became relevant in 1991 to publish the "Instructions for Exercises in Plant Physiology" again to improve preparation and the efficient organization of practical work. Associate Professor RNDr. A. Košturiak, CSc., contributed significantly to the expansion of the introductory part of the instructions with his valuable advice, for which the authors are grateful. For the fourth edition, some tasks were updated and modernized, taking into account the possibilities of the renovated laboratory. The selection of tasks was adapted to the current scope of exercises for individual plant physiology subjects within the bachelor's and master's study programs in biology and ecology. These subjects include: Plant Physiology, Plant Metabolism, Mineral Nutrition of Plants, Plant Growth and Development, and Plant Ecology. Some tasks are also suitable for high school experiments.

The choice of topics was influenced by the research focus of our workplace on secondary metabolism, ecophysiology, and medicinal plants. The instructions generally adhere to the SI unit system, occasionally including other commonly used units.

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E-book

Jozef Kováčik

These "Exercise Manuals" present a concise overview of commonly used methodologies as well as progressive techniques, such as the use of liquid chromatography and fluorescence microscopy. Individual tasks were selected based on the research focus of the Department of Botany at the Faculty of Science, Pavol Jozef Šafárik University in Košice, particularly in the context of "stress physiology."

Some tasks can also be utilized within the subject "Plant Ecology." Chamomile (Matricaria chamomilla) is typically used as a model plant for individual tasks due to its long-standing history of research at the Department of Botany and its ease of cultivation under laboratory conditions. The chapters also briefly discuss the significance of monitored parameters, principles of their determination, and metabolism (formation or degradation), aiming to indicate their mutual context.

This approach highlights that determining an individual parameter cannot provide a general explanation for the overall causes and impacts of observed changes; however, it can serve as a basis for testing hypotheses at the level of other parameters.

For deeper study of specific issues, there is an abundance of high-quality international monographs and review articles available.

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E-book

Lucia Andrezálová, Zdeňka Ďuračková,Mária Chomová,Vladimír Jakuš, Miriam Ježovičová, Jana Muchová, Zuzana Országhová,Ingrid Žitňanová

Chemistry and biochemistry at medical faculties are integral parts of basic theoretic knowledge of contemporary graduate. Educational book “Textbook of Medical Chemistry” is destined to students of study branches General Medicine and Dentistry for the course “Medical Chemistry”.

It is structured into 13 chapters concerning several topics: general and physical chemistry, organic chemistry, chemistry of natural substances (static biochemistry), enzymology and oxidative stress.

Individual chapters provide comprehensible explanation of the fundamentals of physico-chemical, chemical and biochemical relationships applying in living systems as well as the knowledge of the structure of biologically important molecules (simple molecules and macromolecules) related to their properties and biological function.

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E-book

Peter Fedoročko (ed.)

Proceedings of the 7th Annual Doctoral Spring School 2020

From November 10 to November 11, 2020, the 7th annual Spring School for Doctoral Students at Pavol Jozef Šafárik University in Košice will take place in Košice in a modified mode in the on-line space. The scientific program of the spring school will comprise 2 plenary lectures by leading scientific experts of Pavol Jozef Šafárik University in Košice. Doctoral students will present their research papers in two sections: 24 doctoral students of Faculty of Public Administration, Faculty of Law and Faculty of Arts, and 22 doctoral students of Faculty of Medicine and Faculty of Science.

The scientific programme of the spring school will also include a panel discussion with the management of Pavol Jozef Šafárik University in Košice.

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E-book

Miroslava Martinková

This electronic material provides the basic principles of creating a systematic nomenclature of organic compounds, from the simplest hydrocarbons to the more complicated nomenclature of carbohydrates. For some groups of derivatives, alternative ways of generating system names are also mentioned, as well as the most common trivial names that are still in use in the literature and in practice, in some cases being the characteristic (dominant) ones. In the introductory section, the basic rules to be respected when writing names of organic compounds are discussed. This document is intended primarily for interdisciplinary undergraduate and graduate students as support material for the courses Organic Chemistry and Selected Chapters in Organic Chemistry and Biochemistry. In the final section of this document, solved examples are given so that the student can check how the rules for forming the names of organic compounds have been understood.

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