UNINFOS 2014 • Univerzitné informačné systémy (Zborník abstraktov)

E-book

Terézia Kisková - Stanislav Matéffy - Františka Horváthová

The laboratory rat (Rattus norvegicus) is one of the most commonly used experimental animals. It serves as a model organism for analyzing numerous biological processes and pathological mechanisms, such as cardiovascular diseases, metabolic disorders (e.g., lipid metabolism, diabetes mellitus), neurological and neuropsychiatric conditions (e.g., stroke, epilepsy, or Alzheimer's disease), neurobehavioral research, autoimmune diseases (e.g., arthritis), cancer, and renal diseases. It offers many unique advantages for modeling human diseases, testing drugs and natural substances, and studying responses to environmental factors. The size of the laboratory rat, compared to the mouse, creates ideal conditions for physiological manipulations. Additionally, rats are used in clinical toxicology to test chemical substances (Hedrich, 2000).

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E-book

Karel Saksl

Solving crystal structures is the royal discipline of X-ray crystallography. Its primary task, with the exception of defects, is to describe the atomic structure of the motif that, by its repetition, fills the volume of the entire crystal or crystalline phase. This task is nowadays more or less routine for single-crystal X-ray diffraction, which can locate hundreds to thousands of non-hydrogen atoms in large unit cells. However, in real practice, we often have material available only in powder form instead of single crystals. Solving the atomic structure from its X-ray diffraction data is non-trivial, mainly because the three-dimensional diffraction space of a single crystal is reduced to one dimension by measuring a large number of randomly oriented microcrystals (crystallites). Therefore, the solution itself requires, in addition to proper measurement methodology, the selection of suitable tools, procedures, and strategies that, through optimization, will lead to the solution and refinement of the given crystalline phase. The current limit of this method is approximately 100 non-hydrogen atoms in the asymmetric part of the unit cell, which, however, is sufficient for most inorganic materials.

The goal of these educational texts is to provide students in the second and third levels of university studies with specific guidance on solving crystal structures from powder X-ray diffraction data. These scripts build upon my first monograph and require practical knowledge of its content. Similar to my previous monograph, I offer solved examples without a deep theoretical introduction, demonstrating procedures and strategies leading to the correct solution of crystalline phases using the freely available GSAS-II program. The examples are arranged from simpler to more complex, and the reader will find many useful pieces of information in the literature references as well as in the comments below the line. Part of these scripts are data intended for your individual practice of the described procedures. 

Karel Sakls

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Ján Kleban a kolektív

Predkladaný pracovný zošit na praktické cvičenia z cytológie je určený poslucháčom 1. ročníka bakalárskeho štúdia biológie a 1. ročníka bakalárskeho medziodborového štúdia v kombinácii s biológiou na Prírodovedeckej fakulte Univerzity Pavla Jozefa Šafárika v Košiciach. Slúži ako návod, ktorý má študentom uľahčiť prácu a umožniť rýchlejšiu orientáciu v zadanej úlohe. Úprava pracovného zošita do formy protokolov umožňuje študentom zakresliť vlastné pozorovanie a tým stimuluje študentov k presnejšiemu a trvalejšiemu zapamätaniu si precvičovanej úlohy a zároveň umožňuje spätnú kontrolu pedagógom. Počas cvičení sa študenti postupne oboznámia so základnými pojmami optiky, s aplikáciami využívajúcimi mikroskopickú techniku, ale aj so základnými rozdielmi medzi štruktúrou rastlinnej a živočíšnej bunky a ich organelami.

E-book

Erik Čižmár

The textbook "Special Practicum II" is dedicated to describing experimental methods used for studying the magnetic properties of solid materials, especially low-dimensional and molecular magnets. It subsequently contains instructions for the practical exercise "Special Practicum II," during which master's and doctoral students use state-of-the-art commercial equipment-an electron paramagnetic resonance (EPR) spectrometer and a SQUID magnetometer.

The introductory chapter briefly describes the origin of magnetism in solids, the role of the crystal field, and magnetic interactions in explaining their magnetic properties. This is followed by an explanation of the principles of EPR, the operation of the EPR spectrometer, and the optimization of its parameters for the specific practical exercise.

The next part of the textbook is devoted to an overview of the behavior of magnetic quantities with changes in magnetic field or temperature in various types of magnets. The textbook concludes with a description of the operating principle of the SQUID magnetometer and an example of its use in a practical exercise measuring the magnetic moment.

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