ABSTRACT BOOK - 72nd Czech-Slovak Pharmacological Days

E-book

Nikita Bobrova kol.

The concept of medical ethics is interpreted as both applied and professional ethics. As a bioethical discipline, it consists of three normative parts: biogenesis, biotherapy, and thanatology. From an ethical perspective, medicine is part of clinical bioethics; however, at the current stage, “evidence-based ethics” is still lacking.

In the context of standardizing health care, there is an excessive development of certain components of bioethics (such as ethical codes and the concept of patient autonomy), but also a reduction, especially of its clinical component (such as communication, thanatology, euthanasia, dysthanasia, and futile treatment). Current legislative efforts are leading to a reduction in the rights of health care workers, particularly in terms of corporate autonomy.

The fundamental task of medical ethics is the cultivation of medical professionalism, which is defined as the professional alignment of expert, ethical, and legal reasoning, and as a starting point for thinking in terms of values, with reflection on the bioethical space in clinical and professional practice.

Since society declares health as its priority, this priority should positively influence the entire health care system, and its basic idea should be a health care system based on a humanistic ethical paradigm with social and professional application.

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Mária Frankovičová - Jana Kaťuchová - Jozef Radoňak a kol.

Vysokoškolská učebnica určená študentom všeobecného lekárstva, ktorá predstavuje kompaktný zdroj informácií nevyhnutných pre úspešné zvládnutie štúdia predmetu chirurgia. Obsahuje kapitoly z chirurgickej propedeutiky, chirurgie krku, hrudníka a brucha, ako aj nadstavbových chirurgických odborov, vrátane traumatológie, neurochirurgie, ortopédie, urológie, cievnej, plastickej, detskej chirurgie a kardiochirurgie.

E-book

Štefan Tóth

Dyslipidemia is one of the main risk factors for the development of cardiovascular diseases. In recent years, extensive research has been conducted, leading to changes in therapeutic recommendations for dyslipidemia. These scripts aim to provide readers in the introductory chapters with information on the basic management of patients with dyslipidemia, procedures, target levels, and available medications and their combinations for achieving target levels, focusing on the practical aspect of dyslipidemia treatment. In the special section of the script, an overview is provided of the basic characteristics, studies of individual available hypolipemics, as well as hypolipemics that are not yet on our market or are still in the stage of clinical trials

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Lucia Dimunová et al.

Nutrition is among the fundamental needs of humans. A good nutritional status directly impacts an individual’s growth and development, health maintenance, and quality of life. This university textbook addresses nutrition in the context of dietetics and therapeutic nutrition, offering an overview of basic food components such as proteins, fats, carbohydrates, vitamins, and minerals.

It provides detailed insights into nutritional requirements across different developmental stages. In assessing nutritional status, it explores evaluation methods, including nutritional screening, anthropometric measurements, clinical assessments, and laboratory tests.

The text clarifies the structure of nutritional care systems for patients in home settings, healthcare facilities, and social institutions through a unified dietary system that defines basic and specialized diets. Alternative nutrition methods are discussed separately, with enteral and parenteral nutrition serving as alternatives during unfavorable health conditions.

The authors focus on application techniques and complications associated with these methods. The book concludes with food safety considerations and foundational principles of the European Union’s food policy. Currently, dietetics and therapeutic nutrition form a critical component of professional training for healthcare students in both undergraduate and postgraduate education, for whom this textbook is designed.

Authors’ Collective

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Radoslav Morochovič - Rastislav Burda -

Ľuboš Tomčovčík - Peter Cibur - Štefan Ivanecký

Vysokoškolský učebný text určený pre študentov všeobecného lekárstva, zubného lekárstva a fyzioterapie, ktorý obsahuje podstatné časti z predmetu úrazová chirurgia potrebných na zvládnutie vysokoškolského štúdia.

E-book

Terézia Kisková - Stanislav Matéffy - Františka Horváthová

The laboratory rat (Rattus norvegicus) is one of the most commonly used experimental animals. It serves as a model organism for analyzing numerous biological processes and pathological mechanisms, such as cardiovascular diseases, metabolic disorders (e.g., lipid metabolism, diabetes mellitus), neurological and neuropsychiatric conditions (e.g., stroke, epilepsy, or Alzheimer's disease), neurobehavioral research, autoimmune diseases (e.g., arthritis), cancer, and renal diseases. It offers many unique advantages for modeling human diseases, testing drugs and natural substances, and studying responses to environmental factors. The size of the laboratory rat, compared to the mouse, creates ideal conditions for physiological manipulations. Additionally, rats are used in clinical toxicology to test chemical substances (Hedrich, 2000).

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E-book

Adriana Boleková et al.

The book is primarily intended for first-year university students, but it is suitable for anyone who needs to learn. Students can find here the basic principles of learning, principles of how to preserve knowledge, how to concentrate without wasting time, how not to stress before a test or exam and many other practical tips. By acquiring simple knowledge, students will be able to learn effectively with the principles of brain-compatible learning in a way that they will acquire as much information as possible in the shortest period of time with maximum retention; that is minimal forgetting.

The book can serve not only as a theoretical background, but also as a practical tool for mastering university education.

The goal was to create a balanced material that would be an interesting source not only for first-year university students, but also for students of higher years and for everyone with a need of lifelong learning.

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E-book

Silvia Mišíková

This learning text deals with heart rhythm disorders. The book is intended for medical students. There are in a simple way characterized bradycardic and tachycardic heart rhythm disorders. The script explains mechanism of arrhythmias, symptoms, diagnostics, and differential diagnostics and treatment. The greatest emphasis is focused on detection of the arrhythmias based on the surface ECG. All arrhythmias are explained by clinical ECG.

In conclusion, there is ECG quiz which consists of 27 clinical ECG records.

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E-book

Erik Dosedla

A uterine scar is currently a significant medical problem. Uterine scars most commonly occur after a Cesarean section, which is one of the most frequent laparotomic surgeries (Yazicioglu et al., 2006). The frequency of Cesarean sections increased between 1990 and 2014 in the USA from 21.2% to 32.2% (Hamilton et al., 2015), in Great Britain from 12% to 26.2% (NHS Maternity Statistics - England, 2013-14: Summary Report, 2015), and in the Slovak Republic from 8.7% to 31% (Národné centrum zdravotníckych informácii, 2016).

After a Cesarean section (CS), there is a risk of abnormal healing of the uterotomic wound, which can result in the development of certain pathological conditions in consecutive pregnancies (uterine rupture, ectopic pregnancy in the Cesarean scar, placental disorders) (Seow et al., 2004; Oyelese and Smulian, 2006; Fitzpatrick et al., 2012). In addition, a defect in the Cesarean scar is associated with chronic dysmenorrhea, chronic pelvic pain, infertility, and postmenstrual spotting (Wang et al., 2009; Bij de Vaate et al., 2011).

Ultrasound is a valuable examination method in the diagnostic and therapeutic management of these pathological conditions.

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E-book

Peter Olexa

Učebné texty „Vybrané kapitoly z gerontológie a geriatrie" sú určené pre štúdium študentov medicíny na Lekárskej fakulty UPJŠ v odbore Všeobecné lekárstvo v rámci výučby klinických špecializačných blokov v odbore Interná medicína - Geriatria .

Vo svojom úvode sa učebné texty venujú demografii z pohľadu starnutia populácie, vysvetľujú základné pojmy ako gerontológia, jej rozdelenie a následne sa zaoberajú aj úlohou a poslaním klinického odboru geriatria. Následne zrozumiteľne opisujú a vysvetľujú základné piliere geriatrickej medicíny, ktorými sú komplexné geriatrické vyšetrenie, základné geriatrické syndrómy, kam patrí krehkosť, malnutrícia, sarkopénia, kognitívne poruchy, a polyfarmácia . V závere sa venujú ageizmu, ktorý je tiež dôležitým javom v dnešnej klinickej medicíne.

MUDr. Peter Olexa, PhD.

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E-book

Magdaléna Hagovská - Alena Buková - Ľubomír Lachváč

Overweight as a risk factor for the development of civilization diseases and urogenital dysfunctions

Overweight and obesity represent a significant risk factor for the development of several diseases of civilisation, such as cardiovascular disease, type 2 diabetes mellitus and various forms of cancer. They also contribute significantly to urogenital dysfunctions such as urinary incontinence, overactive bladder and pelvic organ prolapse. Mechanisms that link excess weight to these dysfunctions include increased intra-abdominal pressure, hormonal changes, and chronic inflammatory processes that negatively affect the structure and function of the urogenital system. Prevention and treatment of overweight and obesity are therefore crucial not only in terms of reducing the risk of civilization diseases, but also in improving the quality of life through the prevention and treatment of urogenital dysfunctions.

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 Helena Mičková a kol. 

Mária Mareková a kol.

Predkladaná vysokoškolská učebnica predstavuje základy biochémie a je určená predovšetkým pre bakalárske  študijné programy (napr. ošetrovateľstvo, fyzioterapia, verejné zdravotníctvo). Vysokoškolská učebnica predstavuje zjednodušenú alternatívu lekárskej biochémie a je svojím obsahom aj rozsahom vhodná pre študentov nelekárskych študijných odborov. Okrem priblíženia základných metabolických dejov prebiehajúcich v organizme človeka, ponúka aj stručný prehľad klinicko-biochemických parametrov štandardne vyšetrovaných pri podozrení na ich poruchy. Snaží sa poskytnúť študentom, predovšetkým zdravotníckych študijných programov, základy lekárskej a klinickej biochémie a oboznámiť ich s najčastejšie používanými metódami v biochemickom laboratóriu v primeranom rozsahu. Chce prispieť k prehĺbeniu vedomostí o metabolizme zdravého, ale i chorého človeka, resp. o klinicko-biochemických diagnostických postupoch a laboratórnych vyšetreniach a vzbudiť záujem o ďalšie vzdelávanie. Budeme radi, ak poslúži nielen ako príprava na skúšku, ale bude inšpiráciou napr. pre realizáciu diplomových prác zameraných na vedecko-výskumnú oblasť klinickej biochémie či laboratórnej medicíny. 

Autorky

Roman Beňačka  a kolektív

Obsahovo i formou nová učebnica všeobecnej patofyziológie v slovenskom jazyku pre štúdium predmetu Patologická fyziológia pre odbor Všeobecné lekrástvo na lekárskych fakultách na Slovensku resp. v zahraniční. Nadväzuje na pedagogické skúsenosti s výučbou klasickej a molekulárnej patofyziológie a tradíciu vysokoškolských učebníc vydávaných Ústavom patofyziológie Lekárskej fakulty v Košiciach (prvá slovenská učebnica i učebnica Všeobecnej patofyziológie). Učebnica popisuje všetky základné témy z nozológie, etiológie a patogenzéy, ktoré sú tradične  predmetom výučby patofyziológie na lekárskych fakultách v európskom priestore. Prináša najnovšie poznatky štýlom i obsahovo v priamej konfrontácii s obdobnou cudzojazyčnou literatúrou a tp v čitateľsky rovnako atraktívnej prezentačnej forme s početnými obrázkami a tabuľkami.

E-book

Eva Ďurovcová - Mária Mareková

Clinical Biochemistry - selected chapters - MEFANET >>> 

After 7 years, we finally reworked the textbook on the subject of clinical biochemistry at UPJŠ FM in Košice. We have innovated information in accordance with recommendations of professional medical societies and added new chapters. As the scope of the subject is limited, the textbook does not cover all issues of biochemical diagnostics. It focuses on disorders of water-ion and acid-base balance disorders, and basic laboratory diagnostics of diseases of selected organs.

The textbook of clinical biochemistry has the ambition to become a practical aid for senior medical students and beginning doctors in the study of laboratory medicine. It should make it easier for them to orientate themselves in routinely used clinical-biochemical examinations and could form a springboard for a more detailed studying of laboratory methods and their use in diagnostic and monitoring algorithms.
Like any medical discipline, clinical biochemistry is evolving rapidly and gradually integrating with other areas of laboratory medicine. New diagnostic methods penetrate deeper into the essence of the biochemical mechanisms of the human body, and "omic" methods are gaining ground. It is almost sure that in a few years, laboratory examination looks quite different from today. If this publication quite hypothetically reaches its next edition, many chapters will need to updated, and new chapters written following the up-to-date status.
Authors thanks to their colleagues and reviewers for their professional comments and constructive criticism of the text - prof. Jaroslav Racek, MD, DrSc. from FM UK in Pilsen.
Authors thanks very kindly too prof. MUDr. Dušan Dobrota, CSc. (JFM UK Martin) and doc. MVDr. Zuzana Kostecká, PhD. (UVMP, Košice), who read and wrote review of this textbook.

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Roman Beňačka a kolektív

Prvé vydanie zborníka vybraných kapitol z Patologickej fyziológie pre zdravotnícke odbory, ktorý má slúžiť pre prípravu patofyziológie študentov Ošetrovateľstva, Verejného zdravotníctva, Fyzioterapie a iných podobných odborov bakalárskeho a magisterského štúdia na Lekárskych fakultách a vysokých školách zdravotného zamerania. Prednosťou učebnice oproti doterajším titulom je zameranie na modernú pedagogickú prezentáciu a štrukturalizáciu textu, pomáhajúcu pri rýchlej orientácii a zapamätaní s ilustratívnymi obrázkami a dátovo bohatými tabuľkami. Kniha je vo formáte obdobnom u zahraničných titulov.