ABSTRACT BOOK - 72nd Czech-Slovak Pharmacological Days

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Tatiana Kimáková

This scientific monograph is a comprehensive scientific work focused on the presence and effects of mercury in the environment, as well as the health risk factors associated with it.

The monograph presents a characterization of mercury in a multidisciplinary scope, discusses its use in industry and healthcare, and describes the negative impacts of mercury on the environment and public health. It also provides proposals and recommendations for at-risk groups. The monograph includes a comprehensive study of mercury concentration in samples of domestic and foreign production commodities and plant samples using the atomic absorption spectrometer AMA 254.

This scientific monograph is suitable for the scientific community, students of medical, veterinary, natural sciences, and agricultural fields, as well as public health students at all three levels of university study. It is also intended for all interested members of the informed public.

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Tatiana Muchová

Ochorenia a poškodenia pečene, žlčníka, žlčových ciest a pankreasu predstavujú závažný diagnostický, klinický aj liečebný problém.

Táto publikácia sa zaoberá diagnostikou ochorení a traumatických poškodení pečene, žlčníka, žlčových ciest a pankreasu.

Medzi zobrazovacie diagnostické modality patrí konvenčná rádiológia – rentgen, ultrasonografia - USG, počítačová tomografia - CT a magnetická rezonancia - MR.

Keďže pojednávam o zobrazovacích modalitách, publikácia je obohatená o množstvo obrazovej dokumentácie (vlastné aj internetové zdroje) ktorá názorne ukazuje jednotlivé ochorenia, poškodenia popisovaných orgánov.

Táto publikácia je venovaná všetkým medikom, kolegom, lekárom, či už z oblasti rádiológie, ale aj pre klinikov z radov chirurgov, internistov, či gastroenterológov.

Publikácia je rozdelená na jednotlivé časti podľa orgánov a podčasti podľa zobrazovacej modality a druhov ochorenia.

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Jana Raková et al.

The proposed university textbook focuses on topics related to nutrition and nutritional recommendations for patients with selected diseases.

The aim is to provide dietary recommendations for patients with cardiovascular diseases, obesity, metabolic syndrome, gastrointestinal and hepatobiliary disorders, and bone and joint diseases. An important part of the content includes nutrition in relation to cancer. Beneficial for the present time is also a chapter focused on food allergies and intolerances.

The publication highlights specific and targeted nutritional interventions as part of the treatment regimen, which is essential to know and follow in a patient's personal life.

PhDr. Jana Raková, PhD.
(on behalf of the authors' collective)

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Nikita Bobrova kol.

The concept of medical ethics is interpreted as both applied and professional ethics. As a bioethical discipline, it consists of three normative parts: biogenesis, biotherapy, and thanatology. From an ethical perspective, medicine is part of clinical bioethics; however, at the current stage, “evidence-based ethics” is still lacking.

In the context of standardizing health care, there is an excessive development of certain components of bioethics (such as ethical codes and the concept of patient autonomy), but also a reduction, especially of its clinical component (such as communication, thanatology, euthanasia, dysthanasia, and futile treatment). Current legislative efforts are leading to a reduction in the rights of health care workers, particularly in terms of corporate autonomy.

The fundamental task of medical ethics is the cultivation of medical professionalism, which is defined as the professional alignment of expert, ethical, and legal reasoning, and as a starting point for thinking in terms of values, with reflection on the bioethical space in clinical and professional practice.

Since society declares health as its priority, this priority should positively influence the entire health care system, and its basic idea should be a health care system based on a humanistic ethical paradigm with social and professional application.

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Monika Halánová-Leonard Siegfried

Although chronic non-communicable diseases currently dominate overall morbidity and mortality in developed countries, epidemics of infectious diseases, especially those caused by new or emerging pathogens, occur more frequently and spread faster and further in new territories. The starting factors of this threat are mainly ecological and climatic changes and changes in human demography and behaviour. The growing resistance to ATB is also very serious, as a result of which there is a significant increase in the incidence of infectious diseases and their spread to new geographical locations. Current problems of epidemiology and microbiology in research and clinical practice are mainly focused on rapid detection and subsequent response to diagnosed diseases. The correct diagnosis of an infectious disease is the result of a clinical picture, knowledge of the current epidemiological situation and laboratory confirmation of the etiological agent. The identification of microorganisms allows us to establish the correct definitive diagnosis and subsequent targeted therapy, but also to start immediately with appropriate anti-epidemic measures to control the spread of the infectious agent.

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Mária Rašiová

Cardiovascular diseases are among the main causes of morbidity and mortality in developed countries. Academic textbook: Selected Chapters from Angiology is devoted to the most common vascular diseases that the angiologist encounters on a daily basis.

Dilated artery diseases (abdominal aortic aneurysm), as well as stenotizing diseases of peripheral arteries, are described. Diseases such as deep vein thrombosis, thrombophlebitis and chronic venous insufficiency are discussed in the venous vascular system section. I also deal with the most common lymphatic vascular system disease ˗ lymphoedema.

In the individual chapters the risk factors of the diseases, symptoms and signs, diagnostics, treatment modalities (pharmacological therapy, endovascular therapy, angiosurgical therapy) and possible complications of the therapy are briefly analyzed.

My priority was to present the information in a logical, interesting and comprehensible form for students and for common clinical practice.

Author

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Magdaléna Hagovská - Alena Buková - Ľubomír Lachváč

Overweight as a risk factor for the development of civilization diseases and urogenital dysfunctions

Overweight and obesity represent a significant risk factor for the development of several diseases of civilisation, such as cardiovascular disease, type 2 diabetes mellitus and various forms of cancer. They also contribute significantly to urogenital dysfunctions such as urinary incontinence, overactive bladder and pelvic organ prolapse. Mechanisms that link excess weight to these dysfunctions include increased intra-abdominal pressure, hormonal changes, and chronic inflammatory processes that negatively affect the structure and function of the urogenital system. Prevention and treatment of overweight and obesity are therefore crucial not only in terms of reducing the risk of civilization diseases, but also in improving the quality of life through the prevention and treatment of urogenital dysfunctions.

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Peter Berek 

S vývojom endovaskulárnej chirurgie dochádza postupne k rozvoju stentingu ACI. Minimálne invazívny prístup spravil túto metodiku vhodnú pre pacientov s vážnymi konkomitatnými kardiálnymi alebo pľúcnymi ochoreniami. Ďalšou výhodou v porovnaní s chirurgickou liečbou bol lepší prístup k ACI u pacientov po rádioterapii, po predchádzajúcich operáciách na krku, ale aj u pacientov so stenózami blízko lebečnej bázy. Porovnanie CEA vs CAS je zaujímavou a diskutabilnou témou mnohých štúdií. Avšak, aj napriek celosvetovému mohutnému rozvoju endovaskulárnej liečby karotická endarterektómia ostáva zlatým štandardom liečby stenózy ACI u symptomatických aj asymptomatických pacientov.

V tejto monografii by sme radi akcentovali a systematizovali problematiku chirurgickej prevencie CMP z pohľadu cievneho chirurga.

Michal Legiňa kol.

Progress in biology and medicine has always been significantly related to advances in physics. Not only has physics supplied instruments and methods of measurement that have led to many discoveries in physiology and medicine, but methods of physical research have changed many of the older approaches to the biologic sciences. Such circumstances have even led to development of a new scientific field: biophysics, which uses to a great extent physical instrumentation procedures applied to an experimental system. Because any instrument is an additional factor in any experimental system, it may affect the data. To interpret physical data on biological material correctly then, it is necessary to consider the characteristics of instrument response.

A practical course enables a student to acquire some skills, experience and methodological knowledge for performance of experiments and evaluation of measured data. Due to the fast development of instrumentation technology, it is not possible to teach every operation and procedure upon instruments we may use in a future. Besides the basic physical principles, the aim of a practical course is to point out some general rules and skills for instrument operation and for the interpretation of the measured values derived from such operation.

There are two kinds of lessons in practical courses. The first one focuses on laboratory measurements of some important physical quantities and the evaluation of the measured data. These measured quantities are components of the subject “medical biophysics” or of the phenomena studied. Experience provided in managing various scales and tables, as well as in the construction of tables and graphs is substantial. Lessons also enable students to repeat and to strengthen their knowledge of secondary school physics, which is useful for understanding of many phenomena studied in medical biophysics. The second kind of lesson provides experience with some of the diagnostic and therapeutic medical instruments, which can be seen in practical medicine.

The understanding of basic physical principles of corresponding instruments is both recommended and demanded. Theoretical preparation is not only an appropriate condition for the practical managing of the whole lesson, but also helps to avoid injury. This textbook, therefore, intends to help students in preparing for both the practical lessons and the final exam.

Authors

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Terézia Kisková - Stanislav Matéffy - Františka Horváthová

The laboratory rat (Rattus norvegicus) is one of the most commonly used experimental animals. It serves as a model organism for analyzing numerous biological processes and pathological mechanisms, such as cardiovascular diseases, metabolic disorders (e.g., lipid metabolism, diabetes mellitus), neurological and neuropsychiatric conditions (e.g., stroke, epilepsy, or Alzheimer's disease), neurobehavioral research, autoimmune diseases (e.g., arthritis), cancer, and renal diseases. It offers many unique advantages for modeling human diseases, testing drugs and natural substances, and studying responses to environmental factors. The size of the laboratory rat, compared to the mouse, creates ideal conditions for physiological manipulations. Additionally, rats are used in clinical toxicology to test chemical substances (Hedrich, 2000).

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Silvia Danková - Valéria Parová - Gabriela Štefková - Libuša Tirpáková

This university textbook is intended for students of the field of nursing and brings closer the issues in selected clinical fields of nursing, namely dermatovenerology, ophthalmology, otorhinolaryngology and dentistry.

It focuses on the characterization, management of care, reporting and dispensing of specific diseases and nursing care of selected diseases in these fields. It provides important information on the implementation of specific investigative methods and nursing activities that reflect the latest knowledge of the profession, professional guidelines and evidence-based practice.

The authors used relevant sources of domestic and foreign literature as well as electronic sources, which are listed at the end of individual chapters, when processing individual topics. The aim of the authors was to create a university textbook that would help nursing students to orientate themselves in the mentioned clinical fields, or could also be beneficial for nurses in practice.

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Tatiana Kimáková

The scientific monograph focuses on health determinants, healthy nutrition, its fundamental components, the consequences of unhealthy nutrition, and alternative dietary trends. The work also includes research targeting selected lifestyle factors among university students, particularly nutrition, eating habits, and physical activity.

This scientific monograph is suitable for the scientific community, students of medical and natural sciences, and public health professionals at all three levels of higher education. It is equally valuable for members of the informed general public interested in the subject.

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Ingrid Hodorová a kolektív

                Vysokoškolská učebnica „Ultrasonografická anatómia 1“ je určená predovšetkým študentom lekárskych fakúlt. Publikácia dopĺňa medzeru na medicínskom literárnom trhu, na ktorom takýto druh literatúry doteraz absentuje. V učebnici sa čitateľ oboznámi s koreláciou anatomického a ultrasonografického obrazu orgánov a štruktúr za fyziologického stavu. Táto korelácia poukazuje na úzke prepojenie teoretického predmetu anatómia s klinickou praxou s ultrasonografickým vyšetrením, ktoré je dnes neoddeliteľnou súčasťou základných vyšetrovacích metód v mnohých medicínskych odboroch.

                Učebnica pozostáva z anatomickej časti, ktorá sa venuje základnému anatomickému popisu jednotlivých orgánov brucha a panvy. Nosnou časťou učebnice je sonografická časť, ktorá popisuje a charakterizuje jednotlivé ultrasonografické snímky. Čitateľ môže priamo porovnať vzhľad a prípadné rozdiely orgánov a štruktúr získaných dvomi úplne odlišnými zobrazeniami.

                Veríme, že nová vysokoškolská učebnica splní očakávania študentov, ako aj všetkých tých, pre ktorých je oblasť ultrasonografického zobrazenia z pohľadu anatóma predmetom záujmu – bude tak prospešná nielen pre anatómov, ale aj pre začínajúcich sonografistov.

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Eva Slabá-Helena Mičková-Jozef Židzik-Lucia Klimčáková-Janka Vašková

Teaching texts „Practical Lessons in Medical biology“ provide the theoretical foundations of microscopy, various microscopic techniques and preparation of microscopic slides in an understandable form. The chapters of the teaching texts contain model questions and tasks from cytology, molecular biology and genetics enabling students to acquire new knowledge from individual thematic areas and provide instructions for the implementation of tasks during laboratory lessons in medical biology. Teaching texts are primarily intended for the practical lessons in the subjects Biology 1 and Biology 2 for foreign students of the first year of General Medicine and the subjects Medical Biology and Genetics and Regenerative Medicine for foreign students of the first and second year of Dental Medicine at P. J. Šafárik University in Košice – Faculty of Medicine.

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Darina Kluchová a kol. 

An illustrated text for dental students