Praktický sprievodca k hypolipemickej terapii

František Sabola kol.

Although we are not really sure if “Love is coming from the Heart” and nor we know where “the Residence of Soul” is, we are still overwhelmed by its unprecedented effort to keep us alive. Our lives are nowadays fulfilled with enormous chances to satisfy our needs and wishes. Hand in hand is changing our way of life, the intake of calories is growing and the amount of physical activity decreasing. We live longer and maybe happier but our hearts
and vessels are like mirrors showing us how we live. Diseases of the Heart and vessels have become the number one cause of death in highly developed countries including our homeland.
Prevention of cardiovascular diseases has become and an important social and health care system issue. The knowledge requirement of basic principles of cardiology and heart surgery is increasing. Without an understanding of basic principles a good clinical practice is hardly possible.
Together with my Colleagues of Heart surgery department of VÚSCH and LF UPJŠ we prepared this short overview of basic knowledge about surgery of the human heart. We hope that reading it will be more an adventure than a painful journey. If you find some answers to your unanswered questions our effort was not a waste of time.

Authors

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Kvetoslava Rimárová

This manual is published as an auxiliary methodological script for students of bachelor and master courses of medical faculties - especially bachelor and master courses of ‘Public Health’.

Students of general medicine and dentistry can also use these teaching texts as an educational aid when studying the subject “Hygiene”, which is taught either on its own or as part of broader subjects, e.g. “Public Health”. 

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Ingrid Hodorová - Květuše Lovásová

The publication is a continuation of the already published university textbook"Ultrasound Anatomy 1" and fills the gap in the medical literary market concerning the ultrasound view of peripheral nerves and vessels of the limbs, and neck as well.

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Erik Dosedla

Laparoscopic surgical techniques are among the most frequently performed operations today. Throughout their short history, they have undergone many modifications, mainly related to miniaturization and the development of computer technology. The rapid development of laparoscopy over the last twenty years has led to changes in the indications, with minimally invasive procedures gradually replacing standard classical procedures.

Laparoscopic surgery offers significant benefits to the patient, but it also increases the demands on the surgical team.

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Andrea Madarasová Gecková - Daniela Husárová   a kol.

National Report on the Health and Health-Related Behaviour of 11-, 13-, and 15-Year-Old Schoolchildren Based on the Survey Conducted in 2021/2022 within the International Project “Health Behaviour in School-aged Children” (HBSC)

For several years, this study has provided us with key insights for a better understanding of the health-related behaviour of our young people. It examines a range of health-related topics such as sleep, mental well-being, nutritional behaviour, and physical activity. Important areas of research also include school and social relationships within it, family and family background, as well as peer relationships.

The findings deepen our understanding of the mechanisms influencing differences and changes in young people’s health and risk behaviours. They are crucial for the development of effective health promotion programmes and health-related behavioural interventions, educational programmes in this field, and for monitoring their effectiveness—not only at the national but also at the international level. The knowledge gained is important for a better understanding of the needs of schoolchildren and for adapting services and systemic support so that these needs are taken into account to the greatest possible extent in today’s rapidly changing world. The study can help us understand the impact of the COVID-19 pandemic on the quality of both mental and physical health.

The pandemic and the related epidemiological and hygiene measures aimed at limiting the spread of the virus have meant significant restrictions in the daily lives of people of all ages—including children and adolescents. The standard educational process, social contact with peers, extracurricular activities, and other interests both in and out of school were severely disrupted, which had a significant impact on the experiences of schoolchildren.

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Vladimíra Tomečková

Nature, as well as the human body, contains an abundant quantity of organic molecules. This textbook describes selected oxygen, sulfur, nitrogen derivatives of hydrocarbons, heterocyclic compounds of their reactions, which are important in the human body or are found in pharmaceutical active substances, poisons, foodstuffs and heat-treated food. The last part of the textbook describes the isomerism of organic compounds, which enables dynamic changes in the structure of molecules that have different properties. Nature is filled with different plants and animals and is the first laboratory to produce bioactive organic natural compounds. These compounds are compatible with human cells and are applicable as therapeutic medicine. There is an effort to reproduce natural molecules in chemical laboratories, but they cannot be as perfect as the natural ones. Synthetic molecules can serve as a model for multiple studies, but there still does not exist a magic panacea pill or a perfect copy of nature, for the treatment of various diseases. Knowledge about the regenerative and toxic effect of medicinal substances in dependence on their structure (type and number of substituents) is very important for the understanding of their role in modulation of health and disease in dependence on their concentration. Compounds can be used daily only in recommended doses (higher doses can be toxic), but still will not replace a healthy diet. People need a varied diet to be healthy, in which are all necessary nutrients, what Hippocrates demonstrated long ago “Let food be the medicine, and let medicine be the food.” This book is written for students who select bioorganic chemistry subject during the study of general medicine or dentistry as well as for motivated students who would like to practice their knowledge and wish to improve in this subject and for students who would like to learn simplified basic organic reactions with their future application in biochemistry. Learn the simple models mainly through creative simple instruction by using different colours, by repetition, practice by drawing of formulas by hand (at least three times) and memorization of common names of compounds and their reactions which have application in biochemistry. Thus, establishing simple educational methods how to distinguish organic molecules according to the colours of a functional group can promote universal learning for all students who thought that chemistry is a difficult subject, but hopefully they change their opinion after study of this book.

Keywords: organic molecules, oxygen, sulfur, nitrogen derivatives of hydrocarbons, heterocyclic compounds, chemical reactions, isomerism of organic compounds

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Dominika Jarčušková

The script deals with the issue of harmful alcohol use and its consequences on individuals’ cognitive abilities. The first part is devoted to the diagnosis of dependence syndrome and the assessment of risky drinking according to internationally recognized classifications (ICD, DSM). The following chapters explain the concept of cognition and its main components. Attention is also given to changes in cognitive functions during long-term alcohol abuse. The reader is introduced to the anatomical changes in the brain caused by alcohol. Damage to white matter and disorders of neurotransmission are described. Special focus is placed on diagnoses associated with alcohol use, such as Korsakoff syndrome, Wernicke’s encephalopathy, demyelinating disorders, and hepatic encephalopathy. Attention is also paid to the possibilities of diagnosing cognitive dysfunction. General screening tests such as MMSE or MoCA are presented. More specific tools, such as PHES or BEARNI, are described in greater detail. The script also points out the possibilities of pharmacological treatment. Non-pharmacological approaches, including cognitive remediation therapy and computer-based training, are also discussed. The conclusion is devoted to modern neuromodulation methods, in particular transcranial magnetic stimulation and transcranial direct current stimulation. This university textbook is primarily intended for students of medicine, psychology, and related health sciences.

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Sylvia Dražilová - Laura Gombošová - Martin Janičko - Ľubomír Skladaný - Eduard Veseliny

University textbooks are focused on undergraduate medical students and young doctors engaged in specialized training in gastroenterology, hepatology, and internal medicine.

The authors aimed to somewhat replace the lack of a concise and straightforward textbook on gastroenterology and hepatology for medical students, while also providing specific, directly applicable information for young doctors in inpatient departments caring for these patients.

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Pavol Pobeha - Ivana Paraničová - Pavol Joppa

The publication "Respiratory Medicine and Tuberculosis—Selected Chapters" is an anticipated study material intended for medical students at medical faculties and can also serve as supplementary literature in the framework of postgraduate education for specialist doctors. By compiling chapters and content, it builds upon the Slovak version of the publication "Selected Chapters from Pneumology and Phthisiology" (edited by Pavol Joppa), but the new publication expands pneumology with additional nosological units and issues in the context of current evidence-based medicine.

This book adds topics such as Sleep Breathing Disorders and Respiratory Failure to standard pneumology topics like asthma, chronic obstructive pulmonary disease, lung cancer, pneumonia, interstitial diseases, and tuberculosis. These topics are often mentioned only marginally in pneumological publications and within internal diseases. A significant contribution is the comprehensively processed chapter on Cor pulmonale chronicum, which connects several clinical fields including pneumology, internal medicine, and cardiology. We believe that the prepared publication will find favor among readers and will be beneficial in educating students and practitioners.

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Miroslav Gajdoš - Vladimír Kaťuch

  „Neurochirurgia pre študentov medicíny“ je určená pre študentov lekárskych fakúlt. Základné informácie o neurochirurgii získajú aj študenti príbuzných odborov /zubné lekárstvo/, ale aj absolventi lekárskych fakúlt v začiatkoch svojej klinickej praxe.

Učebný text je rozdelený do desiatich kapitol. Tie sa ďalej delia na podkapitoly.

Prvá kapitola je zameraná na dejiny chirurgie, následne na dejiny neurochirurgie. V tejto kapitole autor pripomína, že operované lebky patria k najstarším dôkazom operačnej činnosti našich predkov. 

Druhá a tretia kapitola  je venovaná diagnostike a základným operačným výkonom.

Pre pochopenie patologicko-fyziologických dejov je potrebné pozorne preštudovať štvrtú kapitolu, v ktorej autor popisuje základné patologické mechanizmy, ktoré pôsobia na povrchu ale aj v hĺbke mozgových tkanív.

Piata kapitola je venovaná závažnej problematike  -  vrodeným chybám mozgu, miechy a ich podporných štruktúr.

Nie menej závažnou problematikou pre neurochirurgov sú nádory CNS,  periférnych nervov, lebky a chrbtice. Tie sú popísané v šiestej kapitole.                 

V siedmej kapitole sú popísané cievne ochorenia CNS: autor popisuje aneuryzmy mozgových ciev, ich diagnostiku a liečbu, ďalej cievne malformácie mozgu, artériovenózne malformácie mozgu a v neposlednom rade spinálne artériovenózne malformácie.

8. kapitola je čo do obsahu najrozsiahlejšia. Prináša informácie o poranení pacientov pri úraze. O ich závažnosti, diagnostike a možnej liečbe – konzervatívnej a chirurgickej.

9. kapitola je venovaná nie menej závažnej problematike, a to degeneratívnym ochoreniam chrbtice.

V 10. kapitole sa autor venuje najnovším metódam liečby chronickej bolesti a epileptochirurgii.

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Jaroslava Kopčáková

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Eva Ďurovcová - Mária Mareková

Clinical Biochemistry - selected chapters - MEFANET >>> 

After 7 years, we finally reworked the textbook on the subject of clinical biochemistry at UPJŠ FM in Košice. We have innovated information in accordance with recommendations of professional medical societies and added new chapters. As the scope of the subject is limited, the textbook does not cover all issues of biochemical diagnostics. It focuses on disorders of water-ion and acid-base balance disorders, and basic laboratory diagnostics of diseases of selected organs.

The textbook of clinical biochemistry has the ambition to become a practical aid for senior medical students and beginning doctors in the study of laboratory medicine. It should make it easier for them to orientate themselves in routinely used clinical-biochemical examinations and could form a springboard for a more detailed studying of laboratory methods and their use in diagnostic and monitoring algorithms.
Like any medical discipline, clinical biochemistry is evolving rapidly and gradually integrating with other areas of laboratory medicine. New diagnostic methods penetrate deeper into the essence of the biochemical mechanisms of the human body, and "omic" methods are gaining ground. It is almost sure that in a few years, laboratory examination looks quite different from today. If this publication quite hypothetically reaches its next edition, many chapters will need to updated, and new chapters written following the up-to-date status.
Authors thanks to their colleagues and reviewers for their professional comments and constructive criticism of the text - prof. Jaroslav Racek, MD, DrSc. from FM UK in Pilsen.
Authors thanks very kindly too prof. MUDr. Dušan Dobrota, CSc. (JFM UK Martin) and doc. MVDr. Zuzana Kostecká, PhD. (UVMP, Košice), who read and wrote review of this textbook.

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Martina Čižmáriková a kol. 

The textbook "The Pharmaceutical Compounding Propedeutics for Medical Fields" provides a systematic and comprehensive overview in the field of drug prescription, which is a very important part of pharmacology education for medical and pharmaceutical faculties. In addition to prescribing prescription drugs it also addresses the prescription of dietary foods and medical devices. A significant part of the text is dedicated to the prescription of compounded (extemporaneous) preparations which we consider irreplaceable in many fields of medicine including e. g. paediatrics or dermatology enabling personalized pharmacotherapy.

Importantly, the authors have taken into account recent changes in legislation of the Slovak Republic, including the gradual acceptance of the European Pharmacopoeia since 1995 and the introduction of generic prescription in 2011.

The book consists of the general and special section including 19 pictures, 13 tables and 11 supplements. The great contribution of the publication are abundant examples, quiz questions and tasks which help reader to better understand the particular theoretical basis. The textbook is primary intended for the student of medical and pharmaceutical faculties but it also serves as a great source of information in postgradual education of physicians and pharmacists.

Authors

Gabriela Štefková - Mária Zamboriová - Mária Sováriová Soósová - Renáta Shafout

We would like to introduce the study material/textbook Nursing Care Clinical Procedures I, which was developed to cover the curriculum of Nursing Care 1 for medical students. Clinical procedures are an essential component of nursing practice. The textbook contains four main chapters. Each chapter begins with a general explanation of the topic, followed by detailed method description of procedures to help students deliver high - quality care to patients. Some chapters also include appendi xes in order to pick up some special examples from clinical practice. The textbook strongly describes bandages because a carelessly or improperly applied bandage can cause discomfort to the patient, in many cases it may expose the wound to the danger of infection. To the best of wound knowledge, these procedures reflect currently accepted clinical practice and up-to-date information. The textbook can be easily integrated into an educational programme and can be used in the laboratory as well as in clinical practice. During the preparation of this textbook the information, facts, notes, publications, books and literature presented in the references section were also used. The publication include DVD, which is concentrated on applying bandages from head to lower extremity. DVD was developed in cooperation during IRES project. The student can also find additional information to study by following references. The reading level of Nursing Care Clinical Procedures I is designed to be comprehensible to as many students as possible, including those for whom Engl ish is a second language. We hope that this textbook will be useful to all readers. The authors take no personal responsibility for applying this information to a particular clinical practice
situation.

Martina Vidová Ugurbas

Plastická chirurgia je vysoko špecializovaný medicínsky odbor, ktorý sa zaoberá korekciou defektov, rekonštrukciou a zdokonaľovaním ľudského tela.

Náplňou plastickej chirurgie je korekcia rôznych defektov, vrodených i získaných. Medzi vrodené chyby patria deformity tváre, rázštepy pery a podnebia, deformity ušnice, vrodené vývojové chyby končatín. Najčastejšie získané defekty sú po poraneniach, po chirurgických výkonoch, po fyzikálnych poškodeniach kože a štruktúr krytých kožou.

Do plastickej chirurgie patrí i estetická chirurgia, onkochirurgia a mikrochirurgia, ktorá si zaslúži osobitnú pozornosť. Novými trendami v estetickej chirurgii je rekonštrukcia pomocou tukového tkaniva, kmeňových buniek, používanie rôznych umelých materiálov a implantátov.

Predložené učebné texty v jednotlivých kapitolách popisujú základné princípy plastickej chirurgie, používanie lalokových plastík a iné možnosti krytia defektov. V ôsmych kapitolách sú jednotlivo popísané chirurgické možnosti rekonštrukcie tváre, trupu a končatín. Učebné texty venujú pozornosť malígnym a benígnym kožným tumorom a ich liečbe. Posledná kapitola sa zaoberá najčastejšími estetickými operáciami ako sú augmentácia a redukcia prsníkov, facelifting či blefaroplastika.

 Miroslav Mydlík - Július Vajó (eds.)