Medical Chemistry

Alžbeta Blichárová a kolektív

“Pathology Part 1 (winter semester) - Practical lessons for students of dental medicine” represents the first half of the university textbook designed for the pregradual study of pathology. The textbook complements the lectures of pathology and serves as a source of information for students of dental medicine, that are preparing for the practical as well as the final oral examination.

In this part of the “Pathology” series, fifty-four selected histopathological slides are presented. Each selected slide is provided with general information in relation to etiology and pathogenesis of the disease, as well as with corresponding morphological features, including the gross appearance and the most important histopathological characteristics. The textbook summarizes the basic concepts of general pathology that are necessary to master the broad field of systemic pathology in the second semester.

E-book

Jana Mašlanková

Colorectal carcinoma is the most common malignant tumor of the digestive system, and its rising incidence in Slovakia—particularly among the male population—is alarming. Although significant progress has been made in the diagnosis, screening, and treatment of patients with advanced colorectal cancer, therapeutic options remain limited, necessitating the discovery of additional markers to serve as prognostic predictors.

This monograph aims to draw the attention of the professional community to the critical role and significance of the TGF-β signaling pathway in the initiation, progression, and treatment of colorectal carcinoma. A substantial portion of the text focuses on lesser-known emerging trends and ongoing clinical trials for colorectal cancer patients.

The monograph aspires to provide a balanced resource that serves as an engaging informational tool not only for specialist physicians but also for medical faculty students. By integrating novel insights and clinical data, it seeks to bridge gaps in current understanding and highlight potential avenues for future research and therapy.

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E-publication

Jaroslav Majerník - Andrea Kačmariková

The university textbook "Databases in MS Access – accompanying texts for practical exercises" is intended for medical students, students of non-technical universities, and all beginners in working with databases. It introduces the reader to the issues of database processing and explains the basic principles that need to be known when creating relational databases. It is therefore suitable for those who have not yet worked with databases or who are considering managing their data using their own database. However, even more experienced computer users can find useful information here. This university textbook is written in such a way that its content can be mastered with basic knowledge of working with computers and programs running in any version of the MS Windows operating system.

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Vladimíra Tomečková

Nature, as well as the human body, contains an abundant quantity of organic molecules. This textbook describes selected oxygen, sulfur, nitrogen derivatives of hydrocarbons, heterocyclic compounds of their reactions, which are important in the human body or are found in pharmaceutical active substances, poisons, foodstuffs and heat-treated food. The last part of the textbook describes the isomerism of organic compounds, which enables dynamic changes in the structure of molecules that have different properties. Nature is filled with different plants and animals and is the first laboratory to produce bioactive organic natural compounds. These compounds are compatible with human cells and are applicable as therapeutic medicine. There is an effort to reproduce natural molecules in chemical laboratories, but they cannot be as perfect as the natural ones. Synthetic molecules can serve as a model for multiple studies, but there still does not exist a magic panacea pill or a perfect copy of nature, for the treatment of various diseases. Knowledge about the regenerative and toxic effect of medicinal substances in dependence on their structure (type and number of substituents) is very important for the understanding of their role in modulation of health and disease in dependence on their concentration. Compounds can be used daily only in recommended doses (higher doses can be toxic), but still will not replace a healthy diet. People need a varied diet to be healthy, in which are all necessary nutrients, what Hippocrates demonstrated long ago “Let food be the medicine, and let medicine be the food.” This book is written for students who select bioorganic chemistry subject during the study of general medicine or dentistry as well as for motivated students who would like to practice their knowledge and wish to improve in this subject and for students who would like to learn simplified basic organic reactions with their future application in biochemistry. Learn the simple models mainly through creative simple instruction by using different colours, by repetition, practice by drawing of formulas by hand (at least three times) and memorization of common names of compounds and their reactions which have application in biochemistry. Thus, establishing simple educational methods how to distinguish organic molecules according to the colours of a functional group can promote universal learning for all students who thought that chemistry is a difficult subject, but hopefully they change their opinion after study of this book.

Keywords: organic molecules, oxygen, sulfur, nitrogen derivatives of hydrocarbons, heterocyclic compounds, chemical reactions, isomerism of organic compounds

E-book

Jana Raková - Mária Sováriová Soósová (eds.)

The profession of nursing and the development of the field of nursing care are influenced by international, societal, political, social, and cultural conditions. The result of the long-term evolution of nursing is today's network of universities and higher education institutions that prepare qualified nurses capable of providing high-quality nursing care. Healthcare professionals are trained to meet the new demands imposed by contemporary society and the labor market. Nurses are at the center of most healthcare teams, playing a key role in promoting and protecting health as well as providing nursing care across primary, secondary, and tertiary sectors.

The presented scientific anthology includes contributions of both professional and scientific nature from domestic and international authors (from the Czech Republic, Poland, and Lithuania), addressing current requirements for the development of the nursing profession. The central theme focuses on legislative changes concerning the nursing profession in Slovakia as well as in an international context. The connection between theory and practice encompasses topics related to community care, specifics of patient care, and the safety of both patients and healthcare workers.

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Gabriela Štefková - Mária Zamboriová - Mária Sováriová Soósová - Renáta Shafout

We would like to introduce the study material/textbook Nursing Care Clinical Procedures I, which was developed to cover the curriculum of Nursing Care 1 for medical students. Clinical procedures are an essential component of nursing practice. The textbook contains four main chapters. Each chapter begins with a general explanation of the topic, followed by detailed method description of procedures to help students deliver high - quality care to patients. Some chapters also include appendi xes in order to pick up some special examples from clinical practice. The textbook strongly describes bandages because a carelessly or improperly applied bandage can cause discomfort to the patient, in many cases it may expose the wound to the danger of infection. To the best of wound knowledge, these procedures reflect currently accepted clinical practice and up-to-date information. The textbook can be easily integrated into an educational programme and can be used in the laboratory as well as in clinical practice. During the preparation of this textbook the information, facts, notes, publications, books and literature presented in the references section were also used. The publication include DVD, which is concentrated on applying bandages from head to lower extremity. DVD was developed in cooperation during IRES project. The student can also find additional information to study by following references. The reading level of Nursing Care Clinical Procedures I is designed to be comprehensible to as many students as possible, including those for whom Engl ish is a second language. We hope that this textbook will be useful to all readers. The authors take no personal responsibility for applying this information to a particular clinical practice
situation.

E-book

Mária Sováriová Soósová, Renáta Suchanová, Libuša Tirpáková

Predkladaná vysokoškolská učebnica prináša poznatky z oblasti ošetrovateľskej starostlivosti u pacientov s ochoreniami srdcovo-cievneho systému. Je určená pre poslucháčov odboru ošetrovateľstvo v rámci pregraduálneho a postgraduálneho vzdelávania, sestrám pracujúcim v tejto oblasti, ako aj ďalším odborníkom z nelekárskych vedných disciplín, ktorí sa zaoberajú starostlivosťou o pacientov s kardio-vaskulárnymi chorobami.

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 Helena Mičková a kol. 

E-book

Jaroslava Kopčáková

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Darina Kluchová 

E-book

Marianna Vitková

Current classification of demyelinating diseases of the central nervous system according to van der Knaap and Valko from 2005 includes 97 congenital and acquired diseases that cause demyelination of the white matter of the brain and spinal cord. Most of these disorders lacks any definitive diagnostic test, so the accurate diagnosis depends on upon clinical symptoms, course of the disease, neurological findings, and the results of neuroimaging and laboratory examinations.

The aim of this textbook is to provide an accurate overview of acquired demyelinating diseases of the CNS, their etiopathogenesis, clinical picture and diagnostic options.

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E-book

Ladislav Kočan-Dušan Rybár-Róbert Rapčan

The autonomic nervous system is a vital component of the peripheral nervous system, responsible for maintaining homeostasis and regulating internal processes within the body. Unlike the voluntary control exerted by the central nervous system, the autonomic nervous system operates involuntarily, innervating smooth organs, vessels, skin glands, and even exerting some influence over skeletal muscles in connection with vegetative functions such as breathing, digestion, and the urinary and gonadal systems. Its impact extends crucially to the cardiac muscles of the heart and plays a significant role in endocrine and metabolic functions, thermoregulation, as well as emotional and behavioral responses, including adaptive reactions to stressors. The aim of this publication is to provide a comprehensive and objective exploration of the anatomical and physiological intricacies of the autonomic nervous system, offering insights into its clinical applications. Within these pages, we meticulously delineate various interventional therapeutic procedures tailored to specific diagnoses related to the autonomic nervous system, aligning each intervention with the anatomical framework of the autonomic system. The efficacy of these procedures is evaluated based on the level of evidence, as per the current recommendations of Evidence-Based Medicine. This publication is primarily crafted for fifth and sixth-year medical students and medical professionals specializing in anesthesiology, intensive care, and pain medicine. It serves as a valuable resource for gaining a deeper understanding of autonomic nervous system function and its clinical implications, facilitating informed decision-making in clinical practice.

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Alžbeta Blichárová - Ľudmila Verbóová - Zuzana Benetinová - Vladimír Tancoš  - Patrícia Kollárová  - Adam Nedoroščík - Erika Štammová  - Pavel Kočan

“Pathology Part 2 (summer semester) - Practical lessons for students of dental medicine” represents the second half of the university textbook designed for the pregradual study of pathology. The textbook complements the lectures of pathology and serves as a source of information for students of dental medicine, that are preparing for the practical credit, as well as the final oral examination.

In this part of the “Pathology” series, forty-four selected histopathological slides are presented. Each selected slide is provided with general information in relation to etiology and pathogenesis of the disease, as well as with corresponding morphological features, including the gross appearance and the most important histopathological characteristics. The textbook summarizes the basic concepts of systemic pathology (pathology of the heart, vessels, lungs, gastrointestinal, urogenital system, breast, musculoskeletal, nervous system, skin and infancy) and pathology of the orofacial region, that is logical continuation and completion of general pathology in the first semester.

Alžbeta Blichárová - Ľudmila Verbóová - Zuzana Benetinová - Vladimír Tancoš  - Patrícia Kollárová  - Adam Nedoroščík - Erika Štammová  - Pavel Kočan

„Patológia 2. časť (letný semester) - Praktické cvičenia pre študentov všeobecného lekárstva“ je druhou časťou vysokoškolskej učebnice predstavujúcou druhú polovicu výučby (letný semester). V tejto časti je popísaných 70 diagnóz, kde každej je venovaná jedna strana. V popise je uvedené poradové číslo zhodujúce sa s číslom preparátu a názov danej diagnózy. Študent sa pri každom preparáte oboznámi so základnými informáciami o danej chorobe, jej makroskopickým a mikroskopickým obrazom. Navyše je vytvorené miesto, v ktorom si študent môže zaznačiť (nakresliť) charakteristický mikroskopický obraz danej choroby. Preparáty v tejto učebnici sú zamerané na špeciálnu patológiu – patológiu pľúc, hematopatológiu, patológiu gastrointestinálneho, urogenitálneho systému, prsníka, endokrinného, pohybového  a nervového systému, kože, novorodeneckého a detského veku.

Tým, že učebnica umožňuje preparáty zakresľovať, vytvára študentom priestor pre trvalejšie zapamätanie si danej problematiky. Je vynikajúcim zdrojom pre prípravu študentov na kolokvium a ústnu skúšku.