Medical Chemistry

E-book

Erik Dosedla

Laparoscopic surgical techniques are among the most frequently performed operations today. Throughout their short history, they have undergone many modifications, mainly related to miniaturization and the development of computer technology. The rapid development of laparoscopy over the last twenty years has led to changes in the indications, with minimally invasive procedures gradually replacing standard classical procedures.

Laparoscopic surgery offers significant benefits to the patient, but it also increases the demands on the surgical team.

Download e-book for free (pdf)

E-book

Terézia Kisková - Stanislav Matéffy - Františka Horváthová

The laboratory rat (Rattus norvegicus) is one of the most commonly used experimental animals. It serves as a model organism for analyzing numerous biological processes and pathological mechanisms, such as cardiovascular diseases, metabolic disorders (e.g., lipid metabolism, diabetes mellitus), neurological and neuropsychiatric conditions (e.g., stroke, epilepsy, or Alzheimer's disease), neurobehavioral research, autoimmune diseases (e.g., arthritis), cancer, and renal diseases. It offers many unique advantages for modeling human diseases, testing drugs and natural substances, and studying responses to environmental factors. The size of the laboratory rat, compared to the mouse, creates ideal conditions for physiological manipulations. Additionally, rats are used in clinical toxicology to test chemical substances (Hedrich, 2000).

Download the e-book for free (pdf)

E-publication

Beáta Grešš HalászMária Sováriová SoósováMartin ČervenýJana Michalková

The aim of this university textbook is to provide a systematically structured teaching text focused on research in health sciences and, at the same time, to offer a practical methodological manual for writing final theses intended for students of medical and non-medical fields of study. The first chapter introduces the topic, maps the historical development of research in medical and non-medical sciences, and explains the concept of evidence-based practice (EBP) in the context of research activities. It also highlights the importance of research for these fields and describes the individual steps, principles, and methodological procedures of scientific work. The second chapter focuses on the basic attributes of research in health sciences, with an emphasis on key definitions, basic research designs, the typology of scientific studies, and the possibilities for using the relevant methodologies. It also includes the interpretation and analytical processing of quantitative data, while the third chapter analogously elaborates on the qualitative research approach. The fourth chapter is devoted to the ethical aspects of scientific research. The fifth chapter focuses on the evaluation of research papers in terms of their quality, structure, content coherence, reliability, and validity. The final sixth chapter provides methodological guidelines for planning, implementing, and processing individual types of final theses, with the aim of offering students practical and clearly structured instructions for their preparation. The publication also includes questions, tasks, and exercises that supplement theoretical knowledge with practical examples. These cases are intended to develop students' ability to design research studies and methodologically correctly prepare final theses.

Download the e-book for free

M.Stupák - P.Urban - J.Mašlanková - M.Mareková