Medical Chemistry

Magdaléna Hagovská a kol. 

Vysokoškolská učebnica Praktická kinezioterapia je určená fyzioterapeutom v rámci pregraduálneho, ale aj postgraduálneho vzdelávania. Je komplexne prepracovanou, opravenou a rozšírenou publikáciou pôvodného textu skrípt Najčastejšie používané liečebné metodiky pre fyzioterapeutov (Hagovská, Mihalečková, 2012).
Fyzioterapia sa dotýka takmer všetkých základných klinických odborov. Z toho vyplýva, že fyzioterapeuti by mali ovládať základné poznatky o špeciálnych metódach, ktoré sa zaoberajú fyzioterapiou vertebrologických a neurologických pacientov, pacientov s ortopedickým ochorením, s gynekologickými a urologickými problémami, a pacientov s psychosomatickou diagnózou. Väčšina popísaných najznámejších 44 liečebných metód obsahuje obrázkovú prílohu, na základe ktorej študenti dokážu lepšie pochopiť uvádzané techniky a predísť chybnému vykonávaniu jednotlivých techník.

Autori

E-book

Peter Berek

University scripts “Visceral pathology of vascular origin“analyze one of the most challenging vascular regions, the aorta and the visceral aortic branches, from the surgical perspective. The diagnostic and the treatment aneurysms of the abdominal aorta are dedicated to the first chapter. Early diagnostic and operative treatment is crucial in the treatment of ruptured aneurysms of the abdominal aorta. Shortening of the interval between the patient’s arrival with ruptured aneurysm of the abdominal aorta into the hospital and the beginning of the operation decreased the perioperative mortality. This shortening, together with the use of the cell savers, led to the dropping of perioperative mortality from 50% to 20%. The diagnostics and surgical treatment of the acute and chronic occlusion of the aorta and iliac arteries are analyzed in the second chapter. In this chapter, the focus is given to the aortobifemoral bypass as “the gold standard“ of the surgical therapy of aortoiliac atherosclerosis. The management of acute mesenteric ischemia is the content of the third chapter. Acute mesenteric ischemia is a severe condition with high mortality. The problem of acute mesenterial ischemia is a delayed diagnostic that is the reason for poor therapeutical outcomes of the disease. The possible imagine studies and operations used in treating acute mesenteric ischemia are brought in this chapter. Chronic mesenteric ischemia leads to cachexia. The diagnosis of chronic mesenterial ischemia is one of the most demanding, and surgical therapy used in the treatment of chronic mesenterial ischemia also belongs to the most challenging operations. Left-sided colon ischemia belongs to the severe complications of the aortoiliac reconstructions. Left-sided colon ischemia has a high mortality. In the prevention of the left-sided colon, ischemia is preserving at least one internal iliac artery. The complex diagnostics treatment of intraabdominal compressive syndromes as Dunbar syndróme, „Nutcracker“ syndróme a Wilkie syndróme, analyzed in the last chapter.

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Želmíra Macejová - Mundher Abdulkareem Salman Aljubouri

         Vysokoškolský učebný text: “ Selected  Rheumatology Topics for Medical Students“ je určený pre študentov lekárskych fakúlt študujúcich v anglickom jazyku v študijnom odbore: General medicine a Dental medicine. Rozsahom sú vhodné pre   pregraduálne štúdium predmetu  interná medicína 5.  Kapitoly uvedené v danom diele zahŕňajú základy reumatológie,  postačujúce  pre absolventov LF UPJŠ.

        Text je prehľadne rozčlenený na :  základné   vyšetrovacie metódy, rozdelenie chorôb na autoimunitné, infekčné artritídy, kryštálmi indukované artritídy,  nezápalové ochorenia v reumatológii, metabolické ochorenia kostí. Obsahom kapitol sú aj najnovšie liečebné možnosti daných ochorení.  V závere je obrazová príloha k ochoreniam spomínaným v samotnom texte.

E-book

Iveta Domoráková - Štefan Tóth - Zuzana Fagová - Eva Mechírová - Alexandra Kunová - Kristína Čurgali - Viera Eliášová - Monika Holodová - Marianna Danková

In our new electronic textbook, FUNDAMENTALS OF HISTOLOGY II – Textbook and Atlas of Microscopic Anatomy of Organs, we present students and the professional public with essential information about the microscopic structure of organs, accompanied by extensive visual documentation of organ structures and clear legends for the microphotographs.

All histological specimens come from the archive of the Institute of Histology and Embryology, are used in practical exercises, and are also included in teaching presentations. The electronic textbook is intended for undergraduate and postgraduate students of general medicine and dentistry at medical faculties, as well as for students of veterinary medicine and pharmacy, and biology students at faculties of natural sciences.

The textbook is designed so that students can find clear explanations of most medical terms and also reinforce their knowledge of professional terminology in Latin. An advantage of the electronic textbook is the ability to enlarge microscopic photographs, allowing detailed observation of structures without any qualitative loss of the viewed image. The microphotographs used in the atlas were taken with the following equipment: Zeiss Promicra and Olympus BX50 with a Canon EOS 2000D digital camera and QP Industrial 3.2 software.

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Helena Mičková -  Jozef Židzik -  Mária Mareková - Marek Stupák - 

Peter Urban

Modelové otázky na prijímacie skúšky pre bakalárske štúdium sú určené záujemcom o bakalárske študijné programy na Univerzite Pavla Jozefa Šafárika v Košiciach, Lekárskej fakulte. Publikácia obsahuje 500 otázok z biológie a 500 otázok z chémie, ktoré tvoria podklady písomných testov na prijímacie skúšky. Otázky na prijímacích skúškach však nemusia presne kopírovať modelové otázky. Testy z chémie a biológie pokrývajú tie okruhy učiva z predmetov biológia a chémia na slovenských gymnáziách, vedomosti z ktorých sú vyžadované od poslucháčov bakalárskych študijných smerov (napr. ošetrovateľstvo, fyzioterapia, verejné zdravotníctvo). Otázky z biológie a z chémie sú predkladané v dvoch samostatných celkoch. Odpovede na otázky sú riešené formou ponúkaných variantných odpovedí, obsahujúcich správne aj nesprávne možnosti. Správne odpovede sú vyznačené v kľúči na konci publikácie.

Príklady z chémie tvoria zvláštnu časť, v ktorej nie sú ponúkané variantné odpovede. Pre lepšiu kontrolu správnosti výpočtu je v zátvorke uvedený jeden správny výsledok (z viacerých možných – líšiacich sa napr. v jednotkách – gramy, miligramy, móly). Autori publikácie sa snažili minimalizovať možné chyby v texte a vyhnúť sa nejednoznačným formuláciám otázok a odpovedí. Modelové otázky sú okrem prípravy na prijímacie skúšky na UPJŠ LF v Košiciach vhodné aj na zopakovanie gymnaziálneho učiva z biológie a chémie pred maturitnou skúškou.

 Kvetoslava Rimárová 

The theme of the presented university textbook is a summary of selected basic knowledge of hygiene - environmental medicine. The script includes significant areas of environmental medicine as a science: the basics of environmental medicine, health and prevention issues of environmental health and risk assessment of potential exposure, the issue of air pollution, indoor pollution, problems of drinking water, the action of soil and solid waste, further issue of housing, nutrition and the impact of working conditions on health. Nutritional factors textbooks dealing with issues of rational nutrition, describe the individual components of nutrition, but also address the issue of food hygiene and the possibilities of foodborne infections. One chapter is also devoted to the impact of environmental conditions on health of children and youth. 

University textbook as a manuscript consists from 199 manuscript pages, is divided into 12 basic chapters, contains 36 citations in the literature.  In the Preface, the issue of categorization of diseases and define the basic concepts of health, prevention. Other chapters deal with the above selected chapters hygiene.

This university textbook comes as a basic university textbook for students of general  medicine in the English language, for students of bachelor's and master's studies  of medical schools - mainly bachelor's and master' program of  "Public health". Students of medicine and dentistry can also use these textbooks as an educational tool in the study of other subjects in the teaching of public health.

Autor

E-book

Iveta Cimbolákováa kol.

The premise “today’s research shapes the healthcare of tomorrow” expresses the importance of medical research and the reason for its pursuit. Scientific research and advances in biomedical sciences, as well as their application in medical practice and in the process of delivering healthcare, nevertheless bring new problems in the area of ethics.

Biomedical research itself requires the precise definition of hypotheses, which are tested both under laboratory conditions and on experimental animals. Although clinical studies on human subjects are expected to benefit individual participants and to advance fundamental biomedical knowledge, they also entail certain risks depending on the nature of the research. These risks must be minimized, and the experiment should be conducted freely while also taking place within specific measures to protect all involved-not only the test subjects, but also the researchers themselves.

The presented publication provides an overview of the general conditions and ethical principles of research involving laboratory animals and human subjects, the issue of professional and ethical assessment of projects, as well as fraud and the publication of results. At present, we are witnessing tremendous progress in molecular biological sciences, which brings ethical dilemmas also in the field of genetics. For this reason, one of the chapters is devoted to the latest findings in this area.

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Jozef Kafka

Behavior, in the slovak language expressed as an intention, belongs to basic mental processes of every individual. In this work I consider it as the basic component of an individual having two sides, outer- and inner side. I present it in the scheme No. 2.

The problem of behavior can not be fully covered, although there is a lot of writing, discussing and experimenting by ancient time.

The work may offer only few comments, approaching maily disorders of behavior. I present the original explanation of these disorders, dividing them on primary and derived ones. Primary disorders create the core of the disorder, derived disorders create a component of other disorders.

My classification of primary disorders is as follows:

1. age dependent disorders of behavior
2. disorders in the dynamical structure and in phases of behavior
3. integrative disorders of behavior, disorders of the will, which is the sign of the developed behavior of the individual.

The work is addresses to everone who is interested in his/her owm behavior, but especially for the Medical faculty and psychiatrists, for students of all our faculties.

Author 

Michal Legiňa kol.

Progress in biology and medicine has always been significantly related to advances in physics. Not only has physics supplied instruments and methods of measurement that have led to many discoveries in physiology and medicine, but methods of physical research have changed many of the older approaches to the biologic sciences. Such circumstances have even led to development of a new scientific field: biophysics, which uses to a great extent physical instrumentation procedures applied to an experimental system. Because any instrument is an additional factor in any experimental system, it may affect the data. To interpret physical data on biological material correctly then, it is necessary to consider the characteristics of instrument response.

A practical course enables a student to acquire some skills, experience and methodological knowledge for performance of experiments and evaluation of measured data. Due to the fast development of instrumentation technology, it is not possible to teach every operation and procedure upon instruments we may use in a future. Besides the basic physical principles, the aim of a practical course is to point out some general rules and skills for instrument operation and for the interpretation of the measured values derived from such operation.

There are two kinds of lessons in practical courses. The first one focuses on laboratory measurements of some important physical quantities and the evaluation of the measured data. These measured quantities are components of the subject “medical biophysics” or of the phenomena studied. Experience provided in managing various scales and tables, as well as in the construction of tables and graphs is substantial. Lessons also enable students to repeat and to strengthen their knowledge of secondary school physics, which is useful for understanding of many phenomena studied in medical biophysics. The second kind of lesson provides experience with some of the diagnostic and therapeutic medical instruments, which can be seen in practical medicine.

The understanding of basic physical principles of corresponding instruments is both recommended and demanded. Theoretical preparation is not only an appropriate condition for the practical managing of the whole lesson, but also helps to avoid injury. This textbook, therefore, intends to help students in preparing for both the practical lessons and the final exam.

Authors

H.Mičková - V.Habalová  - J.Židzik  - E.Slabá

Publikácia je určená záujemcom o štúdium na UPJŠ v Košiciach, Lekárskej fakulte v odbore všeobecné lekárstvo a zubné lekárstvo. Obsahuje 1500 modelových otázok z biológie, ktoré sú spracované v súlade so vzdelávacím programom na gymnáziách a ktoré tvoria podklady písomných testov na prijímacích skúškach. Otázky na prijímacích skúškach však nemusia presne kopírovať otázky v tejto publikácii. Odpovede na otázky sú riešené formou ponúkaných variantných odpovedí obsahujúcich správne aj nesprávne možností, pričom správne odpovede sú uvedené v kľúči na konci publikácie. Táto publikácia vám poskytne možnosť overiť si hĺbku a rozsah vašich vedomostí z biológie, ktoré ste nadobudli počas stredoškolského štúdia a zároveň vám uľahčí prípravu na úspešné absolvovanie prijímacej skúšky. Autori problematiku rozdelili do kapitol, čo vám umožní rýchlo sa zorientovať a zistiť, ktorej oblasti sa musíte v štúdiu viac venovať. Cieľom predkladanej publikácie je umožniť každému uchádzačovi, ktorý má o štúdium na lekárskej fakulte vážny záujem, dobre sa pripraviť na prijímacie konanie a v prípade prijatia, mať dobrý základ na štúdium daného odboru.

E-book

Nikita Bobrov et al.

History of ethics represents a search for basic principle, which would enable a distinction between moral and immoral, good and bad, right and wrong. The main problem lies in motives, methods and consequences of human conduct. The integrity of medical profession puts emphasis on life-long study and practice according to the professional competence, and last but not least on ethical principles and rules of medical ethics.
Medical ethics, as a part of bioethics, is currently taking on a huge importance in everyday clinical practice and must face many serious ethical issues regarding the whole system of health care. On general level the decision-making in medical practice is quite easy, based on the requirement to always act in the patient's best interest. However, it is often difficult to know exactly what is best for the patient, in a certain situation, for this particular patient. Also with each progress in medicine and its globalization, the more aspects of human lives are being affected.

Biomedical research, and the new treatment and diagnostic methods it provides are viewed differently in each country, therefore various cultural, religious, social and legal aspects must be considered in their assessment, as well as the basic principles of medical ethics. Worldwide effort on unifying ethical regulations on certain aspects of health care led to the establishment of many legally recognized documents the doctors must be familiar with.

Teaching ethics to students of medical school aims to educate the future doctors towards ethical decision-making, behaviour and professional conduct according to the basic principles of medical ethics.
This textbook provides the basic information on medical ethics for students of medical faculties and serves as a practical introduction to the most common ethical problems of health care provision for their future professional practise.

Authors

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Janette Baloghová

Všeobecná dermatovenerológia je nosnou časťou dermatovenerológie. Morfológia, popis a charakteristika jednotlivých eflorescencií sú kľúčové v diagnostike a diferenciácii kožných ochorení spolu s dobre odobratou anamnézou. Snahou bolo vytvoriť vysokoškolský učebný text, ktorý tvorí praktický návod ako vyšetrovať pacienta s kožným ochorením. Cieľom jednotlivých kapitol je dokonale si osvojiť dermatologickú terminológiu, fyzikálnym vyšetrením vnímať špeciálne kožné znaky a zmeny, vedieť sa orientovať v algoritme pomocných vyšetrovacích metód a testov a pochopiť rozdielne vlastnosti a charakteristiku kože vzhľadom na vek pacienta, vznik, priebeh a trvanie kožných prejavov. Posledná kapitola predstavuje praktickú topografiu kožných ochorení v tabuľkách. Dermatovenerológia patrí k interdisciplinárnym odborom, preto všeobecná dermatológia bude určite dobrým sprievodcom pri diagnostike kožných ochorení nielen študentov medicíny, ale aj lekárov prvého kontaktu a styčných odborov.

E-book

Miriam Kozárová

The publication "News in Diabetology and Lipidology" focuses on extremely relevant topics in diabetology and lipidology, reflecting the state of these issues in light of the recommendations from professional societies from 2019. In diabetology, it primarily addresses the intensification of antidiabetic treatment using modern drug classes—specifically, incretin enhancers and sodium-glucose cotransporter-2 (SGLT-2) inhibitors (gliflozins). Few medical fields have experienced such a development of new pharmacological options as diabetology has in the last two decades. While pharmacotherapy for type 2 diabetes (DM2) was limited to the use of biguanides, sulfonylurea derivatives, and insulin throughout the second half of the last century, recent years have introduced entirely new groups of oral antidiabetics with cardio- and nephroprotective effects. In lipidology, it pertains to the new recommendations from the European Atherosclerosis Society (EAS) with new treatment goals for serum lipids and lipoproteins, including the use of biological therapies.

This textbook is primarily intended for medical students in doctoral studies and doctoral candidates, as well as for physicians preparing for specialization exams in internal medicine, endocrinology, diabetology, metabolic disorders and nutrition, as well as cardiology and angiology. I believe that readers will find information in this publication that will aid them in their studies and translate into their daily clinical practice.

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Jana Raková et al.

The proposed university textbook focuses on topics related to nutrition and nutritional recommendations for patients with selected diseases.

The aim is to provide dietary recommendations for patients with cardiovascular diseases, obesity, metabolic syndrome, gastrointestinal and hepatobiliary disorders, and bone and joint diseases. An important part of the content includes nutrition in relation to cancer. Beneficial for the present time is also a chapter focused on food allergies and intolerances.

The publication highlights specific and targeted nutritional interventions as part of the treatment regimen, which is essential to know and follow in a patient's personal life.

PhDr. Jana Raková, PhD.
(on behalf of the authors' collective)

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Mária Frankovičová - Jana Kaťuchová - Jozef Radoňak a kol.

Vysokoškolská učebnica určená študentom všeobecného lekárstva, ktorá predstavuje kompaktný zdroj informácií nevyhnutných pre úspešné zvládnutie štúdia predmetu chirurgia. Obsahuje kapitoly z chirurgickej propedeutiky, chirurgie krku, hrudníka a brucha, ako aj nadstavbových chirurgických odborov, vrátane traumatológie, neurochirurgie, ortopédie, urológie, cievnej, plastickej, detskej chirurgie a kardiochirurgie.

Eva Mechírová - Iveta Domoráková

The content of this "Practical lessons" represents a record of the appearance, under the light microscope of the tissues, organs and systems of the human body. In addition, it provides visual guidelines during the practical phase of a histology course. It is hoped that this book will be especially useful to students to understand fully the microscopic structure of human tissues and organs.

Authors