Prehľad dejín biológie, lekárstva a farmácie

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Zuzana Kudličková(ed.)

Proceedings of Abstracts from the Scientific Conference with International Participation Organized on the Occasion of the 50th Anniversary of the Establishment of the Department of Organic Chemistry, Faculty of Science, Pavol Jozef Šafárik University in Košice, held on June 8–10, 2016 in Košice.

The Department of Organic Chemistry was established on February 1, 1966. From its inception, the department’s development prospects have been linked to high-quality scientific research focused on the synthesis of isothiocyanates and the products of their nucleophilic additions. In addition, studies were conducted on the use of cycloaddition, cyclocondensation, and photocyclization reactions of heterocumulenes in the synthesis of heterocycles.

Currently, research at the Department of Organic Chemistry is concentrated on stereoselective syntheses of iminosugars and γ-lactam-β-lactone antibiotics, total synthesis of natural compounds and their analogues possessing a sphingoid structure, research into the synthesis of indole alkaloids from the phytoalexin group, and the synthesis of acetylcholinesterase inhibitors based on acridine and coumarin derivatives.

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Natália Raschmanová - Ľubomír Kováč

The text summarizes the basic knowledge about the functioning of the soil ecosystem with a focus on soil protists and dominant groups of soil animals. Characteristics of each soil animal group include basic morphology, ecology, distribution, population dynamics and their importance in the soil ecosystem. The aim of the text is to gain a basic understanding of the diversity and interactions of soil fauna with the soil environment. It deals with the ecological classification of soil fauna on the basis of body size, presence in the soil during the life cycle, food preference and by locomotion. It highlights important morphological and ecophysiological adaptations of soil fauna to physical and chemical environmental factors. The text also gives an overview of the basic methods in the field collection of soil fauna and their extraction from soil samples under laboratory conditions. It further informs on the method of taxonomic identification and ecological evaluation of soil fauna communities. Discusses the soil fauna of different types of ecosystems. It highlights the differences in soil fauna communities that inhabit grassland and forest habitats, and agricultural soils. This teaching material is intended for students in biology degree programmes.

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Ivana Sotáková-Martin Vavra-Mária Ganajová

This textbook has been designed for the master students of chemistry teaching (combined) at the Faculty of Science, Pavol Jozef Šafárik University in Košice as a source of model school experiments in general and inorganic chemistry. It will be used for teaching the Special Practice of School Experiments I compulsory course. It consists of instructions for experiments related to the selected topics in general and inorganic chemistry as well as the didactic and technical aspects of their performance. Each experiment includes an explanation of the principle, specification of the tools and chemicals needed, working procedure, and the respective apparatus assembly scheme. At the end of each experiment, the observation and explanation necessary for the correct interpretation of the results of the chemical experiment performed are provided. To follow the requirements for the digital transformation of education, selected computer-aided experiments and visualiser projections have been included as well. The next part is focused on the work with the monitoring suitcase, which can be used for making simple field experiments related to environmental topics. The final part is dedicated to attractive experiments that complement the topics in inorganic chemistry and can be used to motivate students. All experiment instructions are in line with the requirements specified by the state educational programmes for primary and grammar schools. This book allows teachers to select appropriate demonstrative experiments or experiments for laboratory classes performed by students themselves. The videos of selected experiments are also available as part of the interactive periodical table of elements operated by the Institute of Chemistry, Faculty of Science, Pavol Jozef Šafárik University in Košice.

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Nataša Tomášková

Selected tasks and problems from biochemistry – metabolism follow biochemistry lectures on metabolism and individual metabolic pathways for students of the second and third year of the bachelor’s degree in the fields of chemistry, biology and their combinations with other fields. Scripts provide an opportunity to better understand the lectured subject matter of metabolism through the solution of tasks and problems as serve as a basis for one-hour exercises. The scripts are divided thematically into eleven chapters, and each chapter contains 10 tasks and 7 problems. At the beginning of the chapters there is a short description and explanation of the given metabolic pathway. However, when solving the tasks, the student must focus mainly on the curriculum that was presented on the given topic in the lecture. Subsequently, at the end of chapter, answers to problems are also presented. These scripts are intentionally accessible only in electronic form. The reason is the effort to continuously update and modernize individual tasks.

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Katarína Cechlárová - Eva Pitoňáková (eds.)

Proceedings of Abstracts from Contributions by Participants of the Student Scientific Conference at the Faculty of Science, UPJŠ in Košice, Held on April 26, 2017

This is the fifth edition of the proceedings from the Student Scientific Conference (ŠVK) at the Faculty of Science, Pavol Jozef Šafárik University in Košice. We are pleased that ŠVK has become an integral part of faculty life and a showcase for the quality of education provided. In 2017, ŠVK took place as part of the traditional Science Days on April 26, 2017. 105 students from the Faculty of Science presented their work. Contributions were organized into 15 sections, supplemented by an open programming competition involving 17 students and the final round of the IHRA competition, which included 27 teams from across Slovakia.

The abstracts in this proceedings demonstrate that students at the Faculty of Science, UPJŠ, acquire knowledge and skills in their field not only through theoretical study of disciplines but also through active engagement in solving partial scientific problems aligned with research goals at the faculty’s institutes. These abstracts also provide an overview of the faculty’s scientific activity, which we believe will be of interest to the broader public.

doc. RNDr. Gabriel Semanišin, PhD.

Dean of the Faculty

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Michal Hnatič - Tomáš Lučivjanský

This textbook is primarily intended for first-year master's degree students at Pavol Jozef Šafárik University in Košice, especially those in the nuclear physics, subnuclear physics, and theoretical physics programs. For many years, these lectures were taught by one of the authors at this university, and naturally, over time, there arose an effort to provide these lectures to students in printed form.

In this textbook, we will focus mainly on classical field theory, its quantization based on the operator approach, and the introduction of interactions. Descriptions based on functional integration, Feynman diagram techniques, and more advanced parts will be covered in a subsequent volume of the textbook. In this context, we want to emphasize that in many modern quantum field theory textbooks, the operator approach is used to a lesser extent and is replaced by the approach using (functional) path integrals.

This is probably due to time considerations, as the functional approach leads much faster to practical calculations. On the other hand, we believe that the operator approach is better from a pedagogical point of view. It is much closer to the traditional quantum mechanics course, which is often based on the Schrödinger or Heisenberg formalism. Therefore, students can much more easily follow the flow of ideas that led to the construction of quantum field theory and its fundamental concepts.

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Mariana Budovská

The aim of writing the university textbook "Selected Heterocyclic Compounds" was to create a study aid for students of the Organic Chemistry program, which provides essential information in a clear format for the subject of Heterocyclic Compounds. In selecting the content of the textbook, the goal was to present basic information about the chemistry of the most significant heterocycles. Given that the summary of chemical knowledge about heterocycles is vast, it was not possible to include all heterocyclic compounds in the content.

The intention was for readers to orient themselves in the field of heterocyclic compounds. Separate chapters included in the content address the nomenclature of heterocycles, basic chemical properties of individual heterocycles, their synthesis and reactions, the occurrence of heterocycles in nature, and their practical applications (medications, dyes, pesticides, detergents, etc.).

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Adela Kravčáková - Stanislav Vokál - Janka Vrláková 

The presented “General Physics IV, Part 1: Atomic Physics” is intended as a basic study material for lectures from General Physics IV in the second year of bachelor-level study of physics and interdisciplinary study in combination with physics at the Faculty of Science, P. J. Šafárik University in Košice. The content covers the first part of the given course of physics, devoted to atomic physics.

The aim of the course is to obtain basic information about the structure of the atom and the electron shell of the atom.

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Gabriela Andrejková - Ľubomír Antoni

Machine learning addresses the issues of how computer programs recognize complex patterns and make decisions based on data. In these university textbooks, we focus on theoretical knowledge in the field of machine learning in which we present the creation of concepts for objects, the preparation of concepts, hypotheses and the process of learning from examples. We describe Boolean formulas and their representations, probabilistic learning, linear and logistic regression, linear modeling and classification. Clustering and the Bayesian approach to machine learning conclude this publication.

University textbooks are intended for students of master's degree programs in computer science.

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Mária Ganajová - Jozef Hanč - Ivana Sotáková - Petra Letošníková (eds.)

The International Conference on Research in Didactics of the Science – DidSci+ 2022, continues in the educational legacy of the successful series of the previous DidSci conferences held from 2004 in Krakow, Prague, Brno, or Trnava. The DidSci+ conferences present a platform for enduring international cooperation, focusing on the frontiers and current challenges in science education research. This special edition of DidSci conferences, celebrating its 10th anniversary, was held in Košice, at the Faculty of Science of Pavol Jozef Šafárik University, from June 26 to 29, 2022. The careful double-blind review process has led to two major publications offering a comprehensive look at the latest advances in STEM and science subjects education. The first volume of selected papers is published as the IOP Conference Series proceedings, Vol. 3037 with open access at https://iopscience.iop.org/issue/1742-6596/3037/1, and is primarily devoted to STEM education, assessment, evaluation, feedback strategies, and teacher development. The second volume of selected papers, published by ŠafárikPress, focuses more on curriculum development, educational innovation, and digital technologies, primarily in chemistry and biology. Both publications are intended for a wide audience, including in-service and pre-service teachers of science subjects, university students in scientific disciplines, researchers in science education, professionals in pedagogical and methodological centers, curriculum developers, and textbook authors.

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Ivan Potočňák a kol.

The textbook represents a study literature on the subject of General chemistry, which is a compulsory subject of bachelor courses in Chemistry and Chemistry -  interdisciplinary study, the first year. This textbook contains 15 + 2 chapters in the whole range of 170 pages that follow the content of lectures and by means of examples and theoretical tasks consolidate and extend knowledge gained from lectures.

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Alena Gessert

Caves have always been very specific places throughout history. In some cultures, they served as sites for sacrifices or remembrance, while in others, they were seen as places where one could cross to the "other side of life." People used caves for shelter, as places to leave messages, to wait out bad weather, and in some cases, even lived in them. During wars in our region, entire families or villages would hide from enemies in caves, or they would use them to conceal weapons.

Today, in most countries, caves are destinations for tourists who want to experience something new and unknown: darkness, high humidity, and the fascinating beauty of underground formations. They are also sought after by cavers who long to explore caves, enter worlds where no human has set foot before, find evidence of previous habitation, or conduct research that continually advances our knowledge.

In the publication you are holding, we present both traditional and less conventional topics about the formation of karst and caves, selected ecological aspects, maps and their creation, significant caves of the world, and the life of people in such areas. We also offer an overview of important karst locations that are definitely worth learning more about or visiting in person. This publication is intended for readers among pupils, students, teachers, and the general public, and we believe it will draw you into this mysterious world.

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Jozef Bednarčík (ed.)

The SFEL school is continuation of the Winter Schools of Synchrotron radiation held in 2011, 2013, 2014 and SFEL 2017, 2018 and 2019. All schools of the series were held here, in Liptovský Ján, where our conference venue offers conditions for friendly and creative atmosphere.

The aim of the SFEL 2022 school is to facilitate the growth of a new Slovak research community with high expertise in the area of high-efficiency RTG laser, synchrotron and neutron sources. The SFEL school is designed for efficient transfer of the rapidly developing know-howin these areas to young generation – researchers and university students. The next aim of the SFEL2022 is strengthening of personal connections between the local Slovak research community and actually forming scientific teams of XFEL users, scientific teams of synchrotron or neutron sources users, respectively.

Slovak research community thus can take advantage of the fact that Slovakia is a shareholder of the European XFEL GmbH company in Hamburg, but also makes more efficient use of other closely related scientific facilities, including ILL and ESRF in Grenoble and DESY in Hamburg.

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Erik Sedlák - Rastislav Varhač -  Patrik Danko - Helena Paulíková - Dušan Podhradský

The presented scripts were created in an effort to update and especially clarify the tasks that are solved in the basic practical exercises in biochemistry students of the 2nd and 3rd year of the bachelor's degree in chemistry, biology and their combinations with other disciplines. Most of the tasks come from the original scripts "Podhradský, Mihalovová: Praktické cvičenia z biochémie, Košice 1989".

Some of them have been modified to a greater or lesser extent and adapted to current conditions in the laboratory. New tasks were also added, such as those dedicated to nucleic acids. The scripts are thematically divided into six separate units, each of which consists of several tasks. The names of the units correspond to the nature of the biomacromolecules, which form their central theme. Theoretical introductions at the beginning of the unit are newly constructed and their main goal is to provide a brief overview of the basic biochemical methods used in the study of biomacromolecules.

These scripts are intentionally only available in electronic form. The reason is the effort to continuously update and modernize individual tasks according to the changing possibilities of our laboratory. We hope that the scripts will fulfill their role and that students will have sufficient theoretical knowledge and practical skills in the field of basic biochemical methods after completing these laboratory exercises.

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Mária Vilková - Zuzana Kudličková - Aneta Salayová - Tomáš Ján Liška

The Nuclear Magnetic Resonance Practicum – Part 1: Quantitative NMR is designed for students taking the NMR Practicals course, which focuses on the practical aspects of quantitative nuclear magnetic resonance (qNMR). This publication builds on previous NMR courses and assumes basic theoretical knowledge of the method, emphasizing experimental procedures, data processing, and result interpretation. qNMR is a precise analytical technique with broad applications in analytical chemistry, pharmaceutical research, biomedicine, and quality control. The script provides a detailed guide to conducting experiments, as well as procedures for analyzing and evaluating acquired data. This publication offers students methodological guidance and support in mastering qNMR analysis and serves as a valuable resource not only during their studies but also for further research in NMR spectroscopy.

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Ondrej Krídlo - Gabriel Semanišin

For computer scientists, the constant challenge is to seek efficient algorithms and various technical and implementation possibilities to improve the computational complexity of currently known algorithms. Partial solutions are offered by approaches such as grid-based methods and parallelization of computation. Quantum computers represent a significant but still unfulfilled promise. From a theoretical perspective, probabilistic and approximation approaches provide very effective solutions, and these are the methods we aim to explore in detail.

These electronic university textbooks serve as supplementary materials for the course Approximation and Probabilistic Algorithms. They were developed from the authors' materials and contributions by Prof. RNDr. Viliam Geffert, DrSc., whom the authors thank for providing the manuscript. Acknowledgments also extend to RNDr. Ján Katrenič, PhD., who prepared the first set of exercises for the course, and Žaneta Semanišinová, who reviewed large portions of the text and contributed suggestions for its improvement.

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