NANOVIR – Nanočastice pre riešenie diagnosticko-terapeutických problémov s COVID-19

E-book

Mariana Budovská

The aim of writing the university textbook "Selected Heterocyclic Compounds" was to create a study aid for students of the Organic Chemistry program, which provides essential information in a clear format for the subject of Heterocyclic Compounds. In selecting the content of the textbook, the goal was to present basic information about the chemistry of the most significant heterocycles. Given that the summary of chemical knowledge about heterocycles is vast, it was not possible to include all heterocyclic compounds in the content.

The intention was for readers to orient themselves in the field of heterocyclic compounds. Separate chapters included in the content address the nomenclature of heterocycles, basic chemical properties of individual heterocycles, their synthesis and reactions, the occurrence of heterocycles in nature, and their practical applications (medications, dyes, pesticides, detergents, etc.).

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Marcel Uhrin - Petr Benda -  Peter Kaňuch

Bats represent a unique group of mammals, characterised by different life strategies. They are the only mammals capable of active flight, which, combined with their almost exclusively nocturnal activity, has led to the evolution of specific adaptations. One of the most striking is echolocation, which enables them to orientate themselves perfectly in their surroundings in the dark. Bats are mainly native to the tropics, but have also colonised areas outside the tropics, which, has led to a complex phenological cycle with active phases and interruptions during hibernation, especially in temperate zones. In this diverse and species-rich group (almost 1,500 known species), there is a wide range of social organisation as well as feeding and roosting strategies. The textbook "Fundamentals of Chiropterology" brings the current state of knowledge about these extraordinary animals in eleven chapters and two appendices for the first time in the Slovak language.

E-book

Michal Jaščur

This is a supporting text for the undergraduate students interested in quan- tum theory of magnetism. The text represents an introduction to various theoretical approaches used in this eld. It is an open material, in the sense that it will be supported by appropriate problems to be solved by student at seminars and also as a homework.

The text consists of four chapters that form closed themes of the in- troductory quantum theory of magnetism. In the rst part we explain the quantum origin of the magnetism illustrating the appearance of the ex- change interaction for the case of hydrogen molecule. The second chapter is devoted to the application of the Bogolyubov inequality to the Heisenberg model and it represents the part which is usually missing in the textbooks of magnetism. The third chapter deals with the standard spin wave-theory including the Bloch and Holstein-Primakoff a approach. Finally, we discuss the application of the Jordan-Wigner transformation to one-dimensional spin-1/2 XY model.

The primary ambition of this supportive text is to explain diverse math- ematical methods and their applications in the quantum theory of mag- netism. The text is written in the form which should be sufficient to de- velop the skills of the students up to the very high level. In fact, it is expected that students following this course will able to make their own original applications of the methods presented in this book.

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E-book

Erik Bruoth - Juraj Šebej - Ľubomír Antoni

In these university-level textbooks, we present the fundamental concepts of networks and graph theory. We explore breadth-first and depth-first graph searching. We present static and dynamic network models. We describe the issue of detecting overlapping and non-overlapping communities in directed and undirected networks. Various approaches to anomaly detection in networks also form an important part of this textbook. The final chapter is dedicated to spectral clustering, which plays a significant role in data mining in network graphs for various application domains.

These textbooks are suitable for first and second-year university students in computer science programs. The study materials are also suitable for students in non-computer science fields, with the aim of improving their knowledge and practical experience in computer science-related areas, and provide an opportunity for students to find employment in IT companies to solve practical tasks.

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E-book

Erik Sedlák - Rastislav Varhač -  Patrik Danko - Helena Paulíková - Dušan Podhradský

The presented scripts were created in an effort to update and especially clarify the tasks that are solved in the basic practical exercises in biochemistry students of the 2nd and 3rd year of the bachelor's degree in chemistry, biology and their combinations with other disciplines. Most of the tasks come from the original scripts "Podhradský, Mihalovová: Praktické cvičenia z biochémie, Košice 1989".

Some of them have been modified to a greater or lesser extent and adapted to current conditions in the laboratory. New tasks were also added, such as those dedicated to nucleic acids. The scripts are thematically divided into six separate units, each of which consists of several tasks. The names of the units correspond to the nature of the biomacromolecules, which form their central theme. Theoretical introductions at the beginning of the unit are newly constructed and their main goal is to provide a brief overview of the basic biochemical methods used in the study of biomacromolecules.

These scripts are intentionally only available in electronic form. The reason is the effort to continuously update and modernize individual tasks according to the changing possibilities of our laboratory. We hope that the scripts will fulfill their role and that students will have sufficient theoretical knowledge and practical skills in the field of basic biochemical methods after completing these laboratory exercises.

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E-book

Renáta Oriňaková(ed.)

Trends in chemistry, research and education at Faculty of Sciences of P.J. Šafárik University Košice

November 4, 2016, Faculty of Natural Sciences, Pavol Jozef Šafárik University, Košice, Slovakia

Organized by:
Faculty of Natural Sciences
Pavol Jozef Šafárik University in Košice
Slovak Chemical Society

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E-book

Ondrej Hutník

The concept of the integral is one of the most significant concepts in mathematics as a whole. In its most primitive form, it was already used by the ancient Greeks in the creation of Euclidean geometry. However, it was only after Descartes' work on analytical geometry in 1637 that mathematicians could begin to consider the integral as a subject of analysis. Descartes' work laid the groundwork for the discovery of infinitesimal calculus by Leibniz and Newton around 1665. At that time, a great dispute arose over the priority of this discovery, dividing scholars of Germany and England into two opposing camps, each favoring their own champion. Today, we know that Newton's work on fluxions and fluents was somewhat earlier, but Leibniz's notation and approach have gained more acceptance in the mathematical world, and the symbols ∫ ∫ and d d are still used today. A brief overview of the history of the integral will be presented in Chapter 1.

Today, there is a plethora of scripts, textbooks, and books dedicated to explaining the concept of the integral. Therefore, every potential author faces the initial question of whether to write another text on this topic. Our affirmative answer to this question was driven by the students' request to find the subject matter of a part of the winter semester of the second year presented in a coherent form. The second motivation is a slightly different approach to the topic. If we consider the methods typically used in solving problems and gaining routine with a certain integral, it mainly involves the Newton-Leibniz formula, and often there is little time left to compute the definite (Riemann) integral using its definition. Therefore, we included a discussion of the Newton integral in Chapter 2, which reflects this fact and is directly related to the indefinite integral, whose various calculation methods receive relatively much attention in the previous semester. Only after that, in Chapter 3, do we build the theory of the Riemann integral, present criteria for its existence, classes of integrable functions, basic properties, and finally its relationship with the Newton integral. Questions primarily concerning geometric applications are addressed in Chapter 4, and in the final chapter, we focus on extending the Riemann integral to unbounded functions and unbounded intervals.

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E-book

Miroslava Martinková

This electronic material focuses on the subject of secondary metabolism and its products - secondary metabolites. The material gives an overview of the basic building blocks and construction mechanisms through which molecules can be synthesized in living organisms (plants). The processes of formation of the mentioned metabolites are explained using the basic mechanisms of organic reactions. Several of the secondary metabolites presented have a remarkable biological profile and are used as therapeutics or serve as lead compounds for the development of novel pharmacological agents. This electronic document is primarily intended for students of the Master's degree programme in Organic Chemistry as supporting material for the profile subject Chemistry of Natural Products.

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E-book

Ivana Šišoláková - Radka Gorejová - Jana Shepa - Renáta Oriňaková

The university textbook "Advanced Electrochemical Methods" is a teaching aid intended for master's or doctoral students studying electrochemical subjects at the Department of Physical Chemistry, Faculty of Science, Pavol Jozef Šafárik University in Košice.

These textbooks follow and further develop textbooks focused on the basic electrochemical methods currently used in modern research. The presented teaching texts are processed in sixteen clear chapters, where they provide a theoretical principle and derivation of electrochemical processes and mechanisms in individual methods. Teaching texts also consist of practical laboratory exercises, in which students can try out the real application of the studied electrochemical methods.

The practical tasks are focused primarily on the demonstration of research that is carried out at our workplace. Students will be able to try, for example, electrochemical modification of the electrode surface, preparation of electrochemical sensors for the determination of analytes, preparation and characterization of a dye-sensitized solar cell or electrochemical evolution of hydrogen.

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E-book

Miroslava Martinková

This electronic material provides the basic principles of creating a systematic nomenclature of organic compounds, from the simplest hydrocarbons to the more complicated nomenclature of carbohydrates. For some groups of derivatives, alternative ways of generating system names are also mentioned, as well as the most common trivial names that are still in use in the literature and in practice, in some cases being the characteristic (dominant) ones. In the introductory section, the basic rules to be respected when writing names of organic compounds are discussed. This document is intended primarily for interdisciplinary undergraduate and graduate students as support material for the courses Organic Chemistry and Selected Chapters in Organic Chemistry and Biochemistry. In the final section of this document, solved examples are given so that the student can check how the rules for forming the names of organic compounds have been understood.

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 Andrej Oriňak - Renáta Oriňaková - Andrea Fedorková

Nanotechnology represent the fastest developing science in the present. They are based on the technologies that enable the matter manipulation at atomic level. Nanotechnology offer prepartion of the new materials with unknown and very specific properties and functions.Recent nanotechnology still stay in formative phase of their development. But more and more they are visible with nano-specific phenomenons in the fundamental control of the properties as well mater behaviour. This is quite possible that without nanotechnology will not work any science to the future, moreover that science will not exist anymore. Nanotechnolgy will give a chance and force to transform world to more environmental and comfortable. Expected is expansion of the nanotechnolgy to molecular nanosystems – heterogenous nets, in which molecules and supramolecules work as the nanodevices. The computers and robots will be reduced to the small and ultrasmall dimensions. In medicine will foremost the application of nanotechnology in genetic therapy and elimination of ageing. Nanosurgery will work at molecular level, cancer cells will be identified early and filtered , then substituted with healthy and unchanged. It is necessary to inform university or high school students  about principles of nanotechnolgy, preparation of the nanostructures, functionality of them and to offer full representation about molecular systems and nanodevices; the methods of nanostructures characterization and about application in miniaturized systems. 

Authors

E-book

Marián Kireš  (ed.)

Proceedings of Abstracts from the Student Scientific Conference of the Faculty of Science, Pavol Jozef Šafárik University in Košice

The Student Scientific Conference (SSC) represents the culmination of long-term and intensive work on a selected topic, collaboration with a supervisor, or a broader team at the workplace. In practice, however, it often marks the beginning of scientific research, focusing on a chosen subject, field, or close cooperation with a future supervisor of a bachelor's, master's, or doctoral thesis.

This year, the Student Scientific Conference took place on April 19, 2023, featuring 14 sections, a programming competition, and the IHRA contest. Bachelor’s and master’s students presented 101 contributions. Additionally, 8 high school students participated non-competitively, presenting their SOČ projects; 14 students took part in the programming competition, and 3 students competed in the IHRA contest.

We believe that the proceedings of abstracts and related documents serve not only as an archive but also as a dignified presentation of scientific activities at our faculty for the wider public.

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Adriana Zeleňáková

Magnetic nanoparticles are extremely interesting magnetic objects that still hide much that is undiscovered, both because of their physical properties and because of their diverse applications. Iron nanoparticles, or iron oxides, are used in medical diagnostics for magnetic resonance imaging, in the treatment of hyperthermia, and an important application is the use of magnetic particles for targeted drug delivery.

The textbook "Magnetic Nanoparticles: Nanomagnetism, Preparation and Advanced Applications" is intended primarily for students of the Master's programme in Physics and students of related disciplines at universities and faculties with a physical, chemical, metallurgical and biophysical focus. The motivation for writing this textbook was to develop study material that would contribute to improving the quality of teaching in the profile subject Nanomaterials and Nanotechnology at the Institute of Physical, Faculty of Sciences, UPJŠ, in the Master's programme Condensed Matter Physics, as well as in the profile subject in the PhD programme Advanced Materials.

The university textbook is divided into eight chapters. The first and second chapters are devoted to basic information about magnetism, the origin of nanomagnetism in nanoparticles and surface phenomena. The third and fourth chapters are devoted to nanomagnetism in nanoparticle systems. The fifth chapter describes in detail individual protocols for investigating the phenomenon of superparamagnetism and the phenomenon of superspin glass using the SQUID device. The sixth chapter describes individual procedures for the preparation of magnetic nanoparticles and the seventh chapter describes individual experimental techniques for the study of magnetic nanoparticles. The final eighth chapter describes the applications of nanoparticles in biomedicine.

During the writing of this textbook, the chapters were prepared using the foreign-language specialist literature listed in the recommended reading list.

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E-book

Juraj Černák

A significant part of inorganic chemistry is coordination chemistry, which deals with coordination compounds. Coordination compounds are numerous because they arise from the combination of central atoms, mostly metals, with ligands, and every organic compound is a potential ligand. This is confirmed by a recent report that American scientists M. Brookhart, C. Schauer, and their colleagues from universities in North Carolina and Washington described the preparation of a rhodium complex with methane as a ligand.

This textbook is based on the long-term experience of the author in teaching and testing this subject. The subject is well-covered in several textbooks of varying difficulty in English; their partial list can be found by readers in the list of used literature at the end of this textbook. On the other hand, in Slovak language, coordination chemistry issues are only marginally covered in several textbooks focused more on general inorganic chemistry but lack a comprehensive view on this topic. From this follows the goal of this proposed textbook - to cover the lack of study literature in this area for Slovak language.

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E-book

Marián Kireš - Renáta Orosová a kol.

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E-book

Jana Shepa (ed.)

The book of abstracts from the second year of the international conference Spring electrochemical meeting is composed of contributions from the participants of this student conference.

The conference consisted of one invited lecture and ten competing student lectures. The message of this meeting is to create a dialogue between students of electrochemistry and the mutual exchange of knowledge. All contributions are professionally processed and inspiring.

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E-book

Mariana Budovská

The aim of writing the university textbook "Selected Heterocyclic Compounds" was to create a study aid for students of the Organic Chemistry program, which provides essential information in a clear format for the subject of Heterocyclic Compounds. In selecting the content of the textbook, the goal was to present basic information about the chemistry of the most significant heterocycles. Given that the summary of chemical knowledge about heterocycles is vast, it was not possible to include all heterocyclic compounds in the content.

The intention was for readers to orient themselves in the field of heterocyclic compounds. Separate chapters included in the content address the nomenclature of heterocycles, basic chemical properties of individual heterocycles, their synthesis and reactions, the occurrence of heterocycles in nature, and their practical applications (medications, dyes, pesticides, detergents, etc.).

Download e-book for free (pdf)

Marcel Uhrin - Petr Benda -  Peter Kaňuch

Bats represent a unique group of mammals, characterised by different life strategies. They are the only mammals capable of active flight, which, combined with their almost exclusively nocturnal activity, has led to the evolution of specific adaptations. One of the most striking is echolocation, which enables them to orientate themselves perfectly in their surroundings in the dark. Bats are mainly native to the tropics, but have also colonised areas outside the tropics, which, has led to a complex phenological cycle with active phases and interruptions during hibernation, especially in temperate zones. In this diverse and species-rich group (almost 1,500 known species), there is a wide range of social organisation as well as feeding and roosting strategies. The textbook "Fundamentals of Chiropterology" brings the current state of knowledge about these extraordinary animals in eleven chapters and two appendices for the first time in the Slovak language.

E-book

Michal Jaščur

This is a supporting text for the undergraduate students interested in quan- tum theory of magnetism. The text represents an introduction to various theoretical approaches used in this eld. It is an open material, in the sense that it will be supported by appropriate problems to be solved by student at seminars and also as a homework.

The text consists of four chapters that form closed themes of the in- troductory quantum theory of magnetism. In the rst part we explain the quantum origin of the magnetism illustrating the appearance of the ex- change interaction for the case of hydrogen molecule. The second chapter is devoted to the application of the Bogolyubov inequality to the Heisenberg model and it represents the part which is usually missing in the textbooks of magnetism. The third chapter deals with the standard spin wave-theory including the Bloch and Holstein-Primakoff a approach. Finally, we discuss the application of the Jordan-Wigner transformation to one-dimensional spin-1/2 XY model.

The primary ambition of this supportive text is to explain diverse math- ematical methods and their applications in the quantum theory of mag- netism. The text is written in the form which should be sufficient to de- velop the skills of the students up to the very high level. In fact, it is expected that students following this course will able to make their own original applications of the methods presented in this book.

Download the e-book for free (pdf)

E-book

Erik Bruoth - Juraj Šebej - Ľubomír Antoni

In these university-level textbooks, we present the fundamental concepts of networks and graph theory. We explore breadth-first and depth-first graph searching. We present static and dynamic network models. We describe the issue of detecting overlapping and non-overlapping communities in directed and undirected networks. Various approaches to anomaly detection in networks also form an important part of this textbook. The final chapter is dedicated to spectral clustering, which plays a significant role in data mining in network graphs for various application domains.

These textbooks are suitable for first and second-year university students in computer science programs. The study materials are also suitable for students in non-computer science fields, with the aim of improving their knowledge and practical experience in computer science-related areas, and provide an opportunity for students to find employment in IT companies to solve practical tasks.

Download e-book for free (pdf)

E-book

Erik Sedlák - Rastislav Varhač -  Patrik Danko - Helena Paulíková - Dušan Podhradský

The presented scripts were created in an effort to update and especially clarify the tasks that are solved in the basic practical exercises in biochemistry students of the 2nd and 3rd year of the bachelor's degree in chemistry, biology and their combinations with other disciplines. Most of the tasks come from the original scripts "Podhradský, Mihalovová: Praktické cvičenia z biochémie, Košice 1989".

Some of them have been modified to a greater or lesser extent and adapted to current conditions in the laboratory. New tasks were also added, such as those dedicated to nucleic acids. The scripts are thematically divided into six separate units, each of which consists of several tasks. The names of the units correspond to the nature of the biomacromolecules, which form their central theme. Theoretical introductions at the beginning of the unit are newly constructed and their main goal is to provide a brief overview of the basic biochemical methods used in the study of biomacromolecules.

These scripts are intentionally only available in electronic form. The reason is the effort to continuously update and modernize individual tasks according to the changing possibilities of our laboratory. We hope that the scripts will fulfill their role and that students will have sufficient theoretical knowledge and practical skills in the field of basic biochemical methods after completing these laboratory exercises.

Download e-book for free (pdf)