Elementary organic molecules in biochemistry

Mária Pallayová - Soňa Grešová - Pavol Švorc - Ivana Bačová

Adekvátne vedomosti z lekárskej fyziológie sú dôležité pre správne porozumenie funkcií jednotlivých orgánových systémov, ako aj pre diagnostiku a správnu liečbu ochorení. Vysokoškolský učebný text Praktické cvičenia z fyziológie je navrhnutý tak, aby dopĺňal prednášky a semináre z Lekárskej fyziológie. Každá kapitola je rozdelená do niekoľkých častí (Úvod, Princíp, Materiál, Postup, Protokol), aby študentom uľahčila porozumenie jednotlivých tém a bola nápomocná pri vypracovávaní laboratórnych protokolov. Jednotlivé kapitoly zahŕňajú ochranu a bezpečnosť pri práci, úvod do fyziológie, hematológiu, kardiovaskulárny systém, respiračný systém a vylučovací systém. Od študentov sa očakáva, že počas praktických cvičení získajú praktické skúsenosti pri riešení jednotlivých úloh zameraných na oblasť lekárskej fyziológie a budú rozvíjať aj dôležité analytické a komunikačné zručnosti, ktoré im pomôžu analyzovať a prezentovať vedecké dáta.

Andrea Madarasová Gecková - Daniela Husárová a kol.

The aim of this publication is to present the latest findings of the international study Health Behavior in School-aged Children (HBSC), regarding the health and health-related behavior of school-aged children in Slovakia.After four years, it again brings information on various topics covering physical and mental health, nutritional behavior, leisure-time activities, use of psychoactive substances, within social environment of school-aged children, including family, school and peers. The publication also presents newfindings connected to objectively measured physical fitness of these children. Finally, data about school-aged children with special educational needs are also presented.The findings play an important role in understanding the needs of the new generation of adolescents and are an important source of information for all those who work with them, not only professionals but also parents.Last but not least, they are also beneficial for all stakeholders and institutions who participate in the preparing of policies and strategies focused on supporting the health of school-aged children.

E-book

Magdaléna Hagovská - Alena Buková - Ľubomír Lachváč

Overweight as a risk factor for the development of civilization diseases and urogenital dysfunctions

Overweight and obesity represent a significant risk factor for the development of several diseases of civilisation, such as cardiovascular disease, type 2 diabetes mellitus and various forms of cancer. They also contribute significantly to urogenital dysfunctions such as urinary incontinence, overactive bladder and pelvic organ prolapse. Mechanisms that link excess weight to these dysfunctions include increased intra-abdominal pressure, hormonal changes, and chronic inflammatory processes that negatively affect the structure and function of the urogenital system. Prevention and treatment of overweight and obesity are therefore crucial not only in terms of reducing the risk of civilization diseases, but also in improving the quality of life through the prevention and treatment of urogenital dysfunctions.

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Alžbeta Blichárová a kolektív

“Pathology Part 1 (winter semester) - Practical lessons for students of dental medicine” represents the first half of the university textbook designed for the pregradual study of pathology. The textbook complements the lectures of pathology and serves as a source of information for students of dental medicine, that are preparing for the practical as well as the final oral examination.

In this part of the “Pathology” series, fifty-four selected histopathological slides are presented. Each selected slide is provided with general information in relation to etiology and pathogenesis of the disease, as well as with corresponding morphological features, including the gross appearance and the most important histopathological characteristics. The textbook summarizes the basic concepts of general pathology that are necessary to master the broad field of systemic pathology in the second semester.

František Sabola kol.

Although we are not really sure if “Love is coming from the Heart” and nor we know where “the Residence of Soul” is, we are still overwhelmed by its unprecedented effort to keep us alive. Our lives are nowadays fulfilled with enormous chances to satisfy our needs and wishes. Hand in hand is changing our way of life, the intake of calories is growing and the amount of physical activity decreasing. We live longer and maybe happier but our hearts
and vessels are like mirrors showing us how we live. Diseases of the Heart and vessels have become the number one cause of death in highly developed countries including our homeland.
Prevention of cardiovascular diseases has become and an important social and health care system issue. The knowledge requirement of basic principles of cardiology and heart surgery is increasing. Without an understanding of basic principles a good clinical practice is hardly possible.
Together with my Colleagues of Heart surgery department of VÚSCH and LF UPJŠ we prepared this short overview of basic knowledge about surgery of the human heart. We hope that reading it will be more an adventure than a painful journey. If you find some answers to your unanswered questions our effort was not a waste of time.

Authors

E-book

Adriana Boleková - Natália Hvizdošová (eds.)

Košický morfologický deň je každoročné májové stretnutie morfológov, ktorého sa zúčastňujú najmä košické morfologické pracoviská. Pri tejto príležitosti sa pravidelne vydáva zborník vedeckých prác. Tohoročný zborník je vydaný pri príležitosti 27. košického morfologického dňa. V zborníku autori prezentujú výsledky svojej vedecko-výskumnej a pedagogickej činnosti, ktoré majú charakter teoretických prehľadových štúdií a výskumných prác.

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E-book

Jana Mašlanková

Colorectal carcinoma is the most common malignant tumor of the digestive system, and its rising incidence in Slovakia—particularly among the male population—is alarming. Although significant progress has been made in the diagnosis, screening, and treatment of patients with advanced colorectal cancer, therapeutic options remain limited, necessitating the discovery of additional markers to serve as prognostic predictors.

This monograph aims to draw the attention of the professional community to the critical role and significance of the TGF-β signaling pathway in the initiation, progression, and treatment of colorectal carcinoma. A substantial portion of the text focuses on lesser-known emerging trends and ongoing clinical trials for colorectal cancer patients.

The monograph aspires to provide a balanced resource that serves as an engaging informational tool not only for specialist physicians but also for medical faculty students. By integrating novel insights and clinical data, it seeks to bridge gaps in current understanding and highlight potential avenues for future research and therapy.

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 Ingrid Schusterová 

To offer our medical students of 5th and 6th classes as well as to professional public (pediatrics, pediatric cardiologists) integrated information from pediatric cardiology, which is based on scientific knowledge of experts and practical requirements including our experiences. The publication will extend given the discipline of cardiovascular risk factors of cardiovascular heart disease and acquired heart diseases, which are more actual at the present time in the children as we as bring the new didactic methods in pediatric cardiology teaching.

Autor

Miroslav Gajdoš - Vladimír Kaťuch

  „Neurochirurgia pre študentov medicíny“ je určená pre študentov lekárskych fakúlt. Základné informácie o neurochirurgii získajú aj študenti príbuzných odborov /zubné lekárstvo/, ale aj absolventi lekárskych fakúlt v začiatkoch svojej klinickej praxe.

Učebný text je rozdelený do desiatich kapitol. Tie sa ďalej delia na podkapitoly.

Prvá kapitola je zameraná na dejiny chirurgie, následne na dejiny neurochirurgie. V tejto kapitole autor pripomína, že operované lebky patria k najstarším dôkazom operačnej činnosti našich predkov. 

Druhá a tretia kapitola  je venovaná diagnostike a základným operačným výkonom.

Pre pochopenie patologicko-fyziologických dejov je potrebné pozorne preštudovať štvrtú kapitolu, v ktorej autor popisuje základné patologické mechanizmy, ktoré pôsobia na povrchu ale aj v hĺbke mozgových tkanív.

Piata kapitola je venovaná závažnej problematike  -  vrodeným chybám mozgu, miechy a ich podporných štruktúr.

Nie menej závažnou problematikou pre neurochirurgov sú nádory CNS,  periférnych nervov, lebky a chrbtice. Tie sú popísané v šiestej kapitole.                 

V siedmej kapitole sú popísané cievne ochorenia CNS: autor popisuje aneuryzmy mozgových ciev, ich diagnostiku a liečbu, ďalej cievne malformácie mozgu, artériovenózne malformácie mozgu a v neposlednom rade spinálne artériovenózne malformácie.

8. kapitola je čo do obsahu najrozsiahlejšia. Prináša informácie o poranení pacientov pri úraze. O ich závažnosti, diagnostike a možnej liečbe – konzervatívnej a chirurgickej.

9. kapitola je venovaná nie menej závažnej problematike, a to degeneratívnym ochoreniam chrbtice.

V 10. kapitole sa autor venuje najnovším metódam liečby chronickej bolesti a epileptochirurgii.

E-book

Adriana Boleková a kol.

The book is primarily intended for first-year university students, but it is suitable for anyone who needs to learn. Students can find here the basic principles of learning, principles of how to preserve knowledge, how to concentrate without wasting time, how not to stress before a test or exam and many other practical tips. By acquiring simple knowledge, students will be able to learn effectively with the principles of brain-compatible learning in a way that they will acquire as much information as possible in the shortest period of time with maximum retention; that is minimal forgetting.

The book can serve not only as a theoretical background, but also as a practical tool for mastering university education. The goal was to create a balanced material that would be an interesting source not only for first-year university students, but also for students of higher years and for everyone with a need of lifelong learning.

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Peter Berek 

S vývojom endovaskulárnej chirurgie dochádza postupne k rozvoju stentingu ACI. Minimálne invazívny prístup spravil túto metodiku vhodnú pre pacientov s vážnymi konkomitatnými kardiálnymi alebo pľúcnymi ochoreniami. Ďalšou výhodou v porovnaní s chirurgickou liečbou bol lepší prístup k ACI u pacientov po rádioterapii, po predchádzajúcich operáciách na krku, ale aj u pacientov so stenózami blízko lebečnej bázy. Porovnanie CEA vs CAS je zaujímavou a diskutabilnou témou mnohých štúdií. Avšak, aj napriek celosvetovému mohutnému rozvoju endovaskulárnej liečby karotická endarterektómia ostáva zlatým štandardom liečby stenózy ACI u symptomatických aj asymptomatických pacientov.

V tejto monografii by sme radi akcentovali a systematizovali problematiku chirurgickej prevencie CMP z pohľadu cievneho chirurga.

E-book

Nikita Bobrova kol.

The concept of medical ethics is interpreted as both applied and professional ethics. As a bioethical discipline, it consists of three normative parts: biogenesis, biotherapy, and thanatology. From an ethical perspective, medicine is part of clinical bioethics; however, at the current stage, “evidence-based ethics” is still lacking.

In the context of standardizing health care, there is an excessive development of certain components of bioethics (such as ethical codes and the concept of patient autonomy), but also a reduction, especially of its clinical component (such as communication, thanatology, euthanasia, dysthanasia, and futile treatment). Current legislative efforts are leading to a reduction in the rights of health care workers, particularly in terms of corporate autonomy.

The fundamental task of medical ethics is the cultivation of medical professionalism, which is defined as the professional alignment of expert, ethical, and legal reasoning, and as a starting point for thinking in terms of values, with reflection on the bioethical space in clinical and professional practice.

Since society declares health as its priority, this priority should positively influence the entire health care system, and its basic idea should be a health care system based on a humanistic ethical paradigm with social and professional application.

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E-book

Iveta Domoráková - Štefan Tóth - Zuzana Fagová - Eva Mechírová - Alexandra Kunová - Kristína Čurgali - Viera Eliášová - Monika Holodová - Marianna Danková

In our new electronic textbook, FUNDAMENTALS OF HISTOLOGY II – Textbook and Atlas of Microscopic Anatomy of Organs, we present students and the professional public with essential information about the microscopic structure of organs, accompanied by extensive visual documentation of organ structures and clear legends for the microphotographs.

All histological specimens come from the archive of the Institute of Histology and Embryology, are used in practical exercises, and are also included in teaching presentations. The electronic textbook is intended for undergraduate and postgraduate students of general medicine and dentistry at medical faculties, as well as for students of veterinary medicine and pharmacy, and biology students at faculties of natural sciences.

The textbook is designed so that students can find clear explanations of most medical terms and also reinforce their knowledge of professional terminology in Latin. An advantage of the electronic textbook is the ability to enlarge microscopic photographs, allowing detailed observation of structures without any qualitative loss of the viewed image. The microphotographs used in the atlas were taken with the following equipment: Zeiss Promicra and Olympus BX50 with a Canon EOS 2000D digital camera and QP Industrial 3.2 software.

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Marián Sabol - Helga Kostelná - Leonard Siegfried

Cieľom učebných textov je poskytnúť študentom medicíny a príbuzných odborov   poznatky o základných imunologických metódach, ktoré sa využívajú v klinickej praxi. V učebných textoch sú zahrnuté metódy na vyšetrenie fagocytózy, komplementu, imunoglobulínov, autoprotilátok,  HLA molekúl a T lymfocytov.  Súčasťou textov sú aj  postupy pre izoláciu a stanovenie počtu vybraných  typov buniek imunitného systému. Kombinácia klasických  metód (rozetové testy, fluorescenčná mikroskopia) a moderných metód   (napríklad prietoková cytometria a  ELISPOT) umožňuje orientáciu v základných laboratórnych metódach imunológie.

Martina Čižmáriková a kol. 

The textbook "The Pharmaceutical Compounding Propedeutics for Medical Fields" provides a systematic and comprehensive overview in the field of drug prescription, which is a very important part of pharmacology education for medical and pharmaceutical faculties. In addition to prescribing prescription drugs it also addresses the prescription of dietary foods and medical devices. A significant part of the text is dedicated to the prescription of compounded (extemporaneous) preparations which we consider irreplaceable in many fields of medicine including e. g. paediatrics or dermatology enabling personalized pharmacotherapy.

Importantly, the authors have taken into account recent changes in legislation of the Slovak Republic, including the gradual acceptance of the European Pharmacopoeia since 1995 and the introduction of generic prescription in 2011.

The book consists of the general and special section including 19 pictures, 13 tables and 11 supplements. The great contribution of the publication are abundant examples, quiz questions and tasks which help reader to better understand the particular theoretical basis. The textbook is primary intended for the student of medical and pharmaceutical faculties but it also serves as a great source of information in postgradual education of physicians and pharmacists.

Authors

E-book

Adriana Boleková (ed.)

Proceedings of Scientific Works

The Košice Morphological Day is an annual May meeting of morphologists, primarily attended by Košice morphological workplaces. On this occasion, a collection of scientific works is regularly published.

This year's collection was published on the occasion of the 23rd Košice Morphological Day, which did not take place due to the poor epidemiological situation.

In the collection, the authors present the results of their scientific-research and pedagogical activities, which are in the form of theoretical overview studies and research works.

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Mária Pallayová - Soňa Grešová - Pavol Švorc - Ivana Bačová

Adekvátne vedomosti z lekárskej fyziológie sú dôležité pre správne porozumenie funkcií jednotlivých orgánových systémov, ako aj pre diagnostiku a správnu liečbu ochorení. Vysokoškolský učebný text Praktické cvičenia z fyziológie je navrhnutý tak, aby dopĺňal prednášky a semináre z Lekárskej fyziológie. Každá kapitola je rozdelená do niekoľkých častí (Úvod, Princíp, Materiál, Postup, Protokol), aby študentom uľahčila porozumenie jednotlivých tém a bola nápomocná pri vypracovávaní laboratórnych protokolov. Jednotlivé kapitoly zahŕňajú ochranu a bezpečnosť pri práci, úvod do fyziológie, hematológiu, kardiovaskulárny systém, respiračný systém a vylučovací systém. Od študentov sa očakáva, že počas praktických cvičení získajú praktické skúsenosti pri riešení jednotlivých úloh zameraných na oblasť lekárskej fyziológie a budú rozvíjať aj dôležité analytické a komunikačné zručnosti, ktoré im pomôžu analyzovať a prezentovať vedecké dáta.

Andrea Madarasová Gecková - Daniela Husárová a kol.

The aim of this publication is to present the latest findings of the international study Health Behavior in School-aged Children (HBSC), regarding the health and health-related behavior of school-aged children in Slovakia.After four years, it again brings information on various topics covering physical and mental health, nutritional behavior, leisure-time activities, use of psychoactive substances, within social environment of school-aged children, including family, school and peers. The publication also presents newfindings connected to objectively measured physical fitness of these children. Finally, data about school-aged children with special educational needs are also presented.The findings play an important role in understanding the needs of the new generation of adolescents and are an important source of information for all those who work with them, not only professionals but also parents.Last but not least, they are also beneficial for all stakeholders and institutions who participate in the preparing of policies and strategies focused on supporting the health of school-aged children.

E-book

Magdaléna Hagovská - Alena Buková - Ľubomír Lachváč

Overweight as a risk factor for the development of civilization diseases and urogenital dysfunctions

Overweight and obesity represent a significant risk factor for the development of several diseases of civilisation, such as cardiovascular disease, type 2 diabetes mellitus and various forms of cancer. They also contribute significantly to urogenital dysfunctions such as urinary incontinence, overactive bladder and pelvic organ prolapse. Mechanisms that link excess weight to these dysfunctions include increased intra-abdominal pressure, hormonal changes, and chronic inflammatory processes that negatively affect the structure and function of the urogenital system. Prevention and treatment of overweight and obesity are therefore crucial not only in terms of reducing the risk of civilization diseases, but also in improving the quality of life through the prevention and treatment of urogenital dysfunctions.

Download the e-book for free (pdf)

Alžbeta Blichárová a kolektív

“Pathology Part 1 (winter semester) - Practical lessons for students of dental medicine” represents the first half of the university textbook designed for the pregradual study of pathology. The textbook complements the lectures of pathology and serves as a source of information for students of dental medicine, that are preparing for the practical as well as the final oral examination.

In this part of the “Pathology” series, fifty-four selected histopathological slides are presented. Each selected slide is provided with general information in relation to etiology and pathogenesis of the disease, as well as with corresponding morphological features, including the gross appearance and the most important histopathological characteristics. The textbook summarizes the basic concepts of general pathology that are necessary to master the broad field of systemic pathology in the second semester.

František Sabola kol.

Although we are not really sure if “Love is coming from the Heart” and nor we know where “the Residence of Soul” is, we are still overwhelmed by its unprecedented effort to keep us alive. Our lives are nowadays fulfilled with enormous chances to satisfy our needs and wishes. Hand in hand is changing our way of life, the intake of calories is growing and the amount of physical activity decreasing. We live longer and maybe happier but our hearts
and vessels are like mirrors showing us how we live. Diseases of the Heart and vessels have become the number one cause of death in highly developed countries including our homeland.
Prevention of cardiovascular diseases has become and an important social and health care system issue. The knowledge requirement of basic principles of cardiology and heart surgery is increasing. Without an understanding of basic principles a good clinical practice is hardly possible.
Together with my Colleagues of Heart surgery department of VÚSCH and LF UPJŠ we prepared this short overview of basic knowledge about surgery of the human heart. We hope that reading it will be more an adventure than a painful journey. If you find some answers to your unanswered questions our effort was not a waste of time.

Authors