Elementary organic molecules in biochemistry

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Terézia Kisková - Stanislav Matéffy - Františka Horváthová

The laboratory rat (Rattus norvegicus) is one of the most commonly used experimental animals. It serves as a model organism for analyzing numerous biological processes and pathological mechanisms, such as cardiovascular diseases, metabolic disorders (e.g., lipid metabolism, diabetes mellitus), neurological and neuropsychiatric conditions (e.g., stroke, epilepsy, or Alzheimer's disease), neurobehavioral research, autoimmune diseases (e.g., arthritis), cancer, and renal diseases. It offers many unique advantages for modeling human diseases, testing drugs and natural substances, and studying responses to environmental factors. The size of the laboratory rat, compared to the mouse, creates ideal conditions for physiological manipulations. Additionally, rats are used in clinical toxicology to test chemical substances (Hedrich, 2000).

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 Terézia Hudáková - Jozef Židzik 

Pomocné učebné texty Biológia a genetika – pracovný zošit pre bakalárske študijné programy na praktické cvičenia z lekárskej biológie a genetiky sú určené predovšetkým pre študentov 1. ročníka bakalárskych odborov na UPJŠ LF v Košiciach (ošetrovateľstvo, fyzioterapia a verejné zdravotníctvo). Sú zamerané tak, aby vybranými praktickými úlohami a modelovými príkladmi vhodne dopĺňali, prehlbovali a ilustrovali látku, ktorú si študent vypočuje na prednáškach, alebo prečíta v učebnici. Dve základné oblasti pokryté v textoch sú cytológia a genetika.

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Tatiana Kimáková

This scientific monograph is a comprehensive scientific work focused on the presence and effects of mercury in the environment, as well as the health risk factors associated with it.

The monograph presents a characterization of mercury in a multidisciplinary scope, discusses its use in industry and healthcare, and describes the negative impacts of mercury on the environment and public health. It also provides proposals and recommendations for at-risk groups. The monograph includes a comprehensive study of mercury concentration in samples of domestic and foreign production commodities and plant samples using the atomic absorption spectrometer AMA 254.

This scientific monograph is suitable for the scientific community, students of medical, veterinary, natural sciences, and agricultural fields, as well as public health students at all three levels of university study. It is also intended for all interested members of the informed public.

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Marián Sabol - Helga Kostelná - Leonard Siegfried

Cieľom učebných textov je poskytnúť študentom medicíny a príbuzných odborov   poznatky o základných imunologických metódach, ktoré sa využívajú v klinickej praxi. V učebných textoch sú zahrnuté metódy na vyšetrenie fagocytózy, komplementu, imunoglobulínov, autoprotilátok,  HLA molekúl a T lymfocytov.  Súčasťou textov sú aj  postupy pre izoláciu a stanovenie počtu vybraných  typov buniek imunitného systému. Kombinácia klasických  metód (rozetové testy, fluorescenčná mikroskopia) a moderných metód   (napríklad prietoková cytometria a  ELISPOT) umožňuje orientáciu v základných laboratórnych metódach imunológie.

Mária Pallayová - Soňa Grešová - Pavol Švorc - Ivana Bačová

Adekvátne vedomosti z lekárskej fyziológie sú dôležité pre správne porozumenie funkcií jednotlivých orgánových systémov, ako aj pre diagnostiku a správnu liečbu ochorení. Vysokoškolský učebný text Praktické cvičenia z fyziológie je navrhnutý tak, aby dopĺňal prednášky a semináre z Lekárskej fyziológie. Každá kapitola je rozdelená do niekoľkých častí (Úvod, Princíp, Materiál, Postup, Protokol), aby študentom uľahčila porozumenie jednotlivých tém a bola nápomocná pri vypracovávaní laboratórnych protokolov. Jednotlivé kapitoly zahŕňajú ochranu a bezpečnosť pri práci, úvod do fyziológie, hematológiu, kardiovaskulárny systém, respiračný systém a vylučovací systém. Od študentov sa očakáva, že počas praktických cvičení získajú praktické skúsenosti pri riešení jednotlivých úloh zameraných na oblasť lekárskej fyziológie a budú rozvíjať aj dôležité analytické a komunikačné zručnosti, ktoré im pomôžu analyzovať a prezentovať vedecké dáta.

Želmíra Macejová - Mundher Abdulkareem Salman Aljubouri

         Vysokoškolský učebný text: “ Selected  Rheumatology Topics for Medical Students“ je určený pre študentov lekárskych fakúlt študujúcich v anglickom jazyku v študijnom odbore: General medicine a Dental medicine. Rozsahom sú vhodné pre   pregraduálne štúdium predmetu  interná medicína 5.  Kapitoly uvedené v danom diele zahŕňajú základy reumatológie,  postačujúce  pre absolventov LF UPJŠ.

        Text je prehľadne rozčlenený na :  základné   vyšetrovacie metódy, rozdelenie chorôb na autoimunitné, infekčné artritídy, kryštálmi indukované artritídy,  nezápalové ochorenia v reumatológii, metabolické ochorenia kostí. Obsahom kapitol sú aj najnovšie liečebné možnosti daných ochorení.  V závere je obrazová príloha k ochoreniam spomínaným v samotnom texte.

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Andrea Madarasová Gecková - Daniela Husárová   a kol.

National Report on the Health and Health-Related Behaviour of 11-, 13-, and 15-Year-Old Schoolchildren Based on the Survey Conducted in 2021/2022 within the International Project “Health Behaviour in School-aged Children” (HBSC)

For several years, this study has provided us with key insights for a better understanding of the health-related behaviour of our young people. It examines a range of health-related topics such as sleep, mental well-being, nutritional behaviour, and physical activity. Important areas of research also include school and social relationships within it, family and family background, as well as peer relationships.

The findings deepen our understanding of the mechanisms influencing differences and changes in young people’s health and risk behaviours. They are crucial for the development of effective health promotion programmes and health-related behavioural interventions, educational programmes in this field, and for monitoring their effectiveness—not only at the national but also at the international level. The knowledge gained is important for a better understanding of the needs of schoolchildren and for adapting services and systemic support so that these needs are taken into account to the greatest possible extent in today’s rapidly changing world. The study can help us understand the impact of the COVID-19 pandemic on the quality of both mental and physical health.

The pandemic and the related epidemiological and hygiene measures aimed at limiting the spread of the virus have meant significant restrictions in the daily lives of people of all ages—including children and adolescents. The standard educational process, social contact with peers, extracurricular activities, and other interests both in and out of school were severely disrupted, which had a significant impact on the experiences of schoolchildren.

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Adriana Boleková et al.

The book is primarily intended for first-year university students, but it is suitable for anyone who needs to learn. Students can find here the basic principles of learning, principles of how to preserve knowledge, how to concentrate without wasting time, how not to stress before a test or exam and many other practical tips. By acquiring simple knowledge, students will be able to learn effectively with the principles of brain-compatible learning in a way that they will acquire as much information as possible in the shortest period of time with maximum retention; that is minimal forgetting.

The book can serve not only as a theoretical background, but also as a practical tool for mastering university education.

The goal was to create a balanced material that would be an interesting source not only for first-year university students, but also for students of higher years and for everyone with a need of lifelong learning.

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Pavol Jarčuška - Pavol Kristian - Ivan Schréter (eds.)

The abstract almanac was issued at the occasion of XXII. Slovak – Czech congress on infectoius diseases held in Jasná.

Overall it contains 70 reports that cover current issues in infectology. Contributions are focused on patients with infections caused by multidrug resistant organisms, HIV infected patients, patients with hepatitis and infections in immunocompromised patients.

Thers is a special section dedicated to new aspects in nursing care.

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Eva Mechírová - Iveta Domoráková

The content of this "Practical lessons" represents a record of the appearance, under the light microscope of the tissues, organs and systems of the human body. In addition, it provides visual guidelines during the practical phase of a histology course. It is hoped that this book will be especially useful to students to understand fully the microscopic structure of human tissues and organs.

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Jozef Židzik - Terézia Hudáková - Martina Šemeláková - Ján Šalagovič

Methods in human genetics and molecular biology encompass various experimental, diagnostic and analytical techniques used to investigate the structure, function, expression, and regulation of genes, as well as general molecular processes in human cells. The university textbook Methods in Human Genetics and Molecular Biology provides a comprehensive overview of classical and modern experimental and analytical procedures. In fifteen chapters, it addresses methods such as PCR, RFLP, FISH, Western blot, DNA sequencing, DNA microarrays, molecular cloning, cytogenetic analysis, and forensic genetic analysis. The book is primarily intended as study material for the course of the same name taught in the 2nd year of study at the UPJŠ Faculty of Medicine, but it can also be used by all university students in the fields of biology, biotechnology, and related disciplines.

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Ján Mojžiš - Ladislav Mirossay -Andrej Miroššay (eds.)

This long-standing scientific conference continues its tradition of fostering collaboration, sharing knowledge, and supporting progress in the fields of pharmacology, pharmacy, toxicology, and biomedical sciences. The 2025 meeting brings together distinguished researchers, clinicians, educators, and students from the Czech Republic, Slovakia, and beyond, united by a common goal—to advance our understanding of pharmacological science and improve human health.

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Pavol Joppa a kol.

University textbooks address the etiopathogenesis, clinical presentation, diagnosis, differential diagnosis, treatment, complications, and prognosis of the most significant non-specific respiratory diseases, including bronchial asthma, chronic obstructive pulmonary disease (COPD), pneumonias, pleural syndrome, lung cancer, interstitial lung diseases (including exogenous allergic alveolitis and sarcoidosis), and sleep apnea syndrome.

The final section on non-specific diseases discusses chronic cor pulmonale as the primary cardiovascular complication of chronic pulmonary diseases.

The last chapter focuses on the etiopathogenesis, diagnosis, treatment, and prevention of pulmonary and extrapulmonary forms of tuberculosis, addressing the scope of phthisiology

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Gabriela Štefková - Mária Zamboriová - Mária Sováriová Soósová - Renáta Shafout

We would like to introduce the study material/textbook Nursing Care Clinical Procedures I, which was developed to cover the curriculum of Nursing Care 1 for medical students. Clinical procedures are an essential component of nursing practice. The textbook contains four main chapters. Each chapter begins with a general explanation of the topic, followed by detailed method description of procedures to help students deliver high - quality care to patients. Some chapters also include appendi xes in order to pick up some special examples from clinical practice. The textbook strongly describes bandages because a carelessly or improperly applied bandage can cause discomfort to the patient, in many cases it may expose the wound to the danger of infection. To the best of wound knowledge, these procedures reflect currently accepted clinical practice and up-to-date information. The textbook can be easily integrated into an educational programme and can be used in the laboratory as well as in clinical practice. During the preparation of this textbook the information, facts, notes, publications, books and literature presented in the references section were also used. The publication include DVD, which is concentrated on applying bandages from head to lower extremity. DVD was developed in cooperation during IRES project. The student can also find additional information to study by following references. The reading level of Nursing Care Clinical Procedures I is designed to be comprehensible to as many students as possible, including those for whom Engl ish is a second language. We hope that this textbook will be useful to all readers. The authors take no personal responsibility for applying this information to a particular clinical practice
situation.

Roman Beňačka a kolektív

Prvé vydanie zborníka vybraných kapitol z Patologickej fyziológie pre zdravotnícke odbory, ktorý má slúžiť pre prípravu patofyziológie študentov Ošetrovateľstva, Verejného zdravotníctva, Fyzioterapie a iných podobných odborov bakalárskeho a magisterského štúdia na Lekárskych fakultách a vysokých školách zdravotného zamerania. Prednosťou učebnice oproti doterajším titulom je zameranie na modernú pedagogickú prezentáciu a štrukturalizáciu textu, pomáhajúcu pri rýchlej orientácii a zapamätaní s ilustratívnymi obrázkami a dátovo bohatými tabuľkami. Kniha je vo formáte obdobnom u zahraničných titulov.

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Magdaléna Hagovská - Alena Buková - Ľubomír Lachváč

Overweight as a risk factor for the development of civilization diseases and urogenital dysfunctions

Overweight and obesity represent a significant risk factor for the development of several diseases of civilisation, such as cardiovascular disease, type 2 diabetes mellitus and various forms of cancer. They also contribute significantly to urogenital dysfunctions such as urinary incontinence, overactive bladder and pelvic organ prolapse. Mechanisms that link excess weight to these dysfunctions include increased intra-abdominal pressure, hormonal changes, and chronic inflammatory processes that negatively affect the structure and function of the urogenital system. Prevention and treatment of overweight and obesity are therefore crucial not only in terms of reducing the risk of civilization diseases, but also in improving the quality of life through the prevention and treatment of urogenital dysfunctions.

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