Textbook of practical physiology: part I - cardiovascular physiology

Jozef Kafka

Behavior, in the slovak language expressed as an intention, belongs to basic mental processes of every individual. In this work I consider it as the basic component of an individual having two sides, outer- and inner side. I present it in the scheme No. 2.

The problem of behavior can not be fully covered, although there is a lot of writing, discussing and experimenting by ancient time.

The work may offer only few comments, approaching maily disorders of behavior. I present the original explanation of these disorders, dividing them on primary and derived ones. Primary disorders create the core of the disorder, derived disorders create a component of other disorders.

My classification of primary disorders is as follows:

1. age dependent disorders of behavior
2. disorders in the dynamical structure and in phases of behavior
3. integrative disorders of behavior, disorders of the will, which is the sign of the developed behavior of the individual.

The work is addresses to everone who is interested in his/her owm behavior, but especially for the Medical faculty and psychiatrists, for students of all our faculties.

Author 

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Ivana Skoumalová - Zuzana Dankulincová

The publication entitled Competencies for clinical practice in the field of communication with the patient serves as the background and teaching material.

The text is structured to bring theoretical knowledge about the topic, current research findings in the field and practical tips for training skills in practice. It provides clear information on individual parts of the training and is designed to acquire knowledge that is the basis for practical skills in medical communication, especially in communication with patients.

It is intended for general and dental students to deepen their knowledge and acquire missing skills in medical communication, which are evidence-based and research-validated skills that have a demonstrable positive impact on patient communication.

Download the e-book for free  (pdf)

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Adriana Boleková - Natália Hvizdošová (eds.)

Košický morfologický deň je každoročné májové stretnutie morfológov, ktorého sa zúčastňujú najmä košické morfologické pracoviská. Pri tejto príležitosti sa pravidelne vydáva zborník vedeckých prác. Tohoročný zborník je vydaný pri príležitosti 27. košického morfologického dňa. V zborníku autori prezentujú výsledky svojej vedecko-výskumnej a pedagogickej činnosti, ktoré majú charakter teoretických prehľadových štúdií a výskumných prác.

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Martina Čižmáriková - Peter Takáč 

It is known that pharmacology is a rapidly evolving medical field, with information about drug forms and their routes of administration constantly changing. In addition to the emergence of new drug forms, new trends are also observed in the routes of administration suitable for delivering drugs. Despite being significant factors influencing the efficacy and safety of pharmacotherapy – an indispensable component of comprehensive patient care – to our knowledge, there has been a lack of comprehensive and detailed textual material focused on this issue on the market. This fact is related to the broader scope of the professional text we are presenting, as rare drug forms or less commonly used routes of administration are only marginally mentioned or not mentioned at all in available pharmacology textbooks.

Our main goal was therefore to provide sufficient information about existing drug forms, their routes of administration, as well as their methods of delivery, which should serve to enhance the quality of pharmacotherapy in the context of so-called "tailored treatment," whose main effort is to individualize treatment for a specific patient. Although the work focuses on drug application methods, a detailed description of the technical implementation of algorithms and other related procedures is the subject of interest for other fields (nursing, surgical propaedeutics, etc.). Overall, it is a supplementary educational text provided in electronic form, which is extremely popular in today's modern informatized era. Thanks to this, the work can be used at any time at home or in a school environment, comprehensively or progressively, partially. We have also tried to enhance its quality by appropriate content organization, inclusion of practical experiences, as well as the inclusion of colorful images or photographs, overview tables, and appendices.

The textbook is supplemented by test quizzes serving to verify acquired selected knowledge, which are published on the website of the Department of Pharmacology at the Medical Faculty of UPJŠ in Košice (under "Teaching" → "Taught subjects"), and which will be continuously supplemented and updated (http://www.lf.upjs.sk/farmakologia/TEST%201.htm; http://www.lf.upjs.sk/farmakologia/TEST%202.htm).

Although the work is primarily intended for medical students, or students of pharmacy and other healthcare fields, we firmly believe that enriching information will be found in it by beginning graduates of these fields, as well as their teachers.

Download the e-book for free (pdf)

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Štefan Tóth

Dyslipidemia is one of the main risk factors for the development of cardiovascular diseases. In recent years, extensive research has been conducted, leading to changes in therapeutic recommendations for dyslipidemia. These scripts aim to provide readers in the introductory chapters with information on the basic management of patients with dyslipidemia, procedures, target levels, and available medications and their combinations for achieving target levels, focusing on the practical aspect of dyslipidemia treatment. In the special section of the script, an overview is provided of the basic characteristics, studies of individual available hypolipemics, as well as hypolipemics that are not yet on our market or are still in the stage of clinical trials

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Mária Rašiová

Cardiovascular diseases are among the main causes of morbidity and mortality in developed countries. Academic textbook: Selected Chapters from Angiology is devoted to the most common vascular diseases that the angiologist encounters on a daily basis.

Dilated artery diseases (abdominal aortic aneurysm), as well as stenotizing diseases of peripheral arteries, are described. Diseases such as deep vein thrombosis, thrombophlebitis and chronic venous insufficiency are discussed in the venous vascular system section. I also deal with the most common lymphatic vascular system disease ˗ lymphoedema.

In the individual chapters the risk factors of the diseases, symptoms and signs, diagnostics, treatment modalities (pharmacological therapy, endovascular therapy, angiosurgical therapy) and possible complications of the therapy are briefly analyzed.

My priority was to present the information in a logical, interesting and comprehensible form for students and for common clinical practice.

Author

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Martina Ružičková - Jozef Dragašek

 MEFANET 

Psychology is becoming increasingly important in people's lives. It is significant to research human behaviour and how people interact with their environment, as well as how they develop physically, mentally, emotionally, and socially. A rising number of people have been both physically and mentally harmed in recent years as a result of cognitive, emotional, or behavioural disorders.

It was determined that a study book on psychology for medical students was required. Presented study book Psychology in Medicine gives students a fundamental insight into patients´ behaviour in general, and demonstrates the role of psychology in relieving health concerns in particular. It includes topics of medical psychology and clinical psychology that are applied in health care. The chapters address the basic principles of human behaviour, communication between patients and physicians, personality psychology, psychodiagnostic techniques, psychotherapy treatment, abnormal psychology, dealing with stressful events and physical illnesses. The study textbook also emphasises the importance of good mental health and self-care in a doctor's practise.

There is a hope that this book will provide both a source of information and inspiration for doctors and all health care professionals.

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Tatiana Kimáková - Vladimír Pavlík

The scientific monograph focuses on the characteristics of free radicals, reactive oxygen and nitrogen species, oxidative stress, and its impact on various diseases. A significant portion is dedicated to antioxidants, their classification based on multiple criteria, the characteristics of selected antioxidants in terms of their functions, manifestations of their deficiency and excess, and the overall antioxidant capacity of the body.

A special section is devoted to enzyme-based antioxidants, natural sources of antioxidants in the form of vitamins, trace elements, flavonoids, polyphenols, and coenzyme Q10. To provide a clearer understanding of antioxidants and their influence on population health, the monograph presents results from a research project included in the program "Research Support for Enhancing the Defense Capabilities of the Czech Republic in NATO Structures."

The research was conducted between 2010 and 2012 as part of preventive rehabilitation programs for professional soldiers with a sports component. The study involved 218 professional soldiers, including 180 men and 38 women, with an average age of 33.3 years. The current health status and dietary habits of the soldiers were assessed using questionnaires.

The study described the saturation of the observed group with antioxidant vitamins and statistically evaluated the relationship between their levels and the risk indicators for the development of cardiovascular diseases. Individual analyses were performed using the Reflotron device calibrated with Reflotron Precinorm control serum. Following blood collection, all participants underwent anthropometric examinations (body weight, height, waist circumference), blood pressure measurements, heart rate monitoring, and physical fitness assessments through simple functional tests.

This scientific monograph is suitable for the scientific community, students of medical, veterinary, and natural sciences, as well as public health students at all levels of university education. It is also intended for informed members of the public.

Authors

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Gabriela Štefková - Mária Zamboriová - Mária Sováriová Soósová - Renáta Shafout

We would like to introduce the study material/textbook Nursing Care Clinical Procedures I, which was developed to cover the curriculum of Nursing Care 1 for medical students. Clinical procedures are an essential component of nursing practice. The textbook contains four main chapters. Each chapter begins with a general explanation of the topic, followed by detailed method description of procedures to help students deliver high - quality care to patients. Some chapters also include appendi xes in order to pick up some special examples from clinical practice. The textbook strongly describes bandages because a carelessly or improperly applied bandage can cause discomfort to the patient, in many cases it may expose the wound to the danger of infection. To the best of wound knowledge, these procedures reflect currently accepted clinical practice and up-to-date information. The textbook can be easily integrated into an educational programme and can be used in the laboratory as well as in clinical practice. During the preparation of this textbook the information, facts, notes, publications, books and literature presented in the references section were also used. The publication include DVD, which is concentrated on applying bandages from head to lower extremity. DVD was developed in cooperation during IRES project. The student can also find additional information to study by following references. The reading level of Nursing Care Clinical Procedures I is designed to be comprehensible to as many students as possible, including those for whom Engl ish is a second language. We hope that this textbook will be useful to all readers. The authors take no personal responsibility for applying this information to a particular clinical practice
situation.

 Magdaléna Hagovská 

The presented material provides a complex view on rehabilitation of patients in neurology. It is a second completely elaborated and extended edition of the original textbook –Neurology overview for physiotherapists. It contains data on etiology of neurological diseases, pathophysiology, examination in physiotherapy and the possibilities of a conservative treatment. From special treatment methods the faciooral therapy, acral coactivation therapy are described in greater details and the possibilities of diagnosis and training of cognitive functions. In annexes standardized questionnaire methods are described, which can be used in degree (final) works. A part of the publication is the Chapter on vertebrogenic syndromes which are frequently observed in neurological disorders. 

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Nikita Bobrova kol.

The concept of medical ethics is interpreted as both applied and professional ethics. As a bioethical discipline, it consists of three normative parts: biogenesis, biotherapy, and thanatology. From an ethical perspective, medicine is part of clinical bioethics; however, at the current stage, “evidence-based ethics” is still lacking.

In the context of standardizing health care, there is an excessive development of certain components of bioethics (such as ethical codes and the concept of patient autonomy), but also a reduction, especially of its clinical component (such as communication, thanatology, euthanasia, dysthanasia, and futile treatment). Current legislative efforts are leading to a reduction in the rights of health care workers, particularly in terms of corporate autonomy.

The fundamental task of medical ethics is the cultivation of medical professionalism, which is defined as the professional alignment of expert, ethical, and legal reasoning, and as a starting point for thinking in terms of values, with reflection on the bioethical space in clinical and professional practice.

Since society declares health as its priority, this priority should positively influence the entire health care system, and its basic idea should be a health care system based on a humanistic ethical paradigm with social and professional application.

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Jana Mašlanková

Colorectal carcinoma is the most common malignant tumor of the digestive system, and its rising incidence in Slovakia—particularly among the male population—is alarming. Although significant progress has been made in the diagnosis, screening, and treatment of patients with advanced colorectal cancer, therapeutic options remain limited, necessitating the discovery of additional markers to serve as prognostic predictors.

This monograph aims to draw the attention of the professional community to the critical role and significance of the TGF-β signaling pathway in the initiation, progression, and treatment of colorectal carcinoma. A substantial portion of the text focuses on lesser-known emerging trends and ongoing clinical trials for colorectal cancer patients.

The monograph aspires to provide a balanced resource that serves as an engaging informational tool not only for specialist physicians but also for medical faculty students. By integrating novel insights and clinical data, it seeks to bridge gaps in current understanding and highlight potential avenues for future research and therapy.

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Tatiana Muchová

Tieto učebné texty sú určené študentom lekárskych fakúlt, obsahuje základné poznatky z rádiológie.

Rádiologické zobrazovacie metódy prežívajú stále výrazný rozvoj vďaka prístrojovej technike, ktorá umožňuje zavádzať nové diagnostické metódy, ako sú USG vyšetrenia s kontrastnou látkou, špeciálne CT vyšetrenia...

Vďaka moderným prístrojom môžeme vykonávať rôzne intervenčné diagnostické aj terapeutické výkony, ako sú biopsie, drenáže...

Publikácia je rozdelená na všeobecnú a špeciálnu časť s následným delením podľa jednotlivých modalít a vyšetrovaných orgánov. 

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Ladislav Kočan-Dušan Rybár-Róbert Rapčan

The autonomic nervous system is a vital component of the peripheral nervous system, responsible for maintaining homeostasis and regulating internal processes within the body. Unlike the voluntary control exerted by the central nervous system, the autonomic nervous system operates involuntarily, innervating smooth organs, vessels, skin glands, and even exerting some influence over skeletal muscles in connection with vegetative functions such as breathing, digestion, and the urinary and gonadal systems. Its impact extends crucially to the cardiac muscles of the heart and plays a significant role in endocrine and metabolic functions, thermoregulation, as well as emotional and behavioral responses, including adaptive reactions to stressors. The aim of this publication is to provide a comprehensive and objective exploration of the anatomical and physiological intricacies of the autonomic nervous system, offering insights into its clinical applications. Within these pages, we meticulously delineate various interventional therapeutic procedures tailored to specific diagnoses related to the autonomic nervous system, aligning each intervention with the anatomical framework of the autonomic system. The efficacy of these procedures is evaluated based on the level of evidence, as per the current recommendations of Evidence-Based Medicine. This publication is primarily crafted for fifth and sixth-year medical students and medical professionals specializing in anesthesiology, intensive care, and pain medicine. It serves as a valuable resource for gaining a deeper understanding of autonomic nervous system function and its clinical implications, facilitating informed decision-making in clinical practice.

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Tatiana Kimáková - Štefan Tóth - Ivan Uher

The scientific monograph is devoted to active and healthy aging, its basic indicators, involutional changes, or the relationship between healthy aging and lifestyle. Adopting a healthy lifestyle and actively participating in health care for yourself are important elements in all stages of our lives, and therefore in healthy aging. We describe the possibilities of older people to slow down the adverse changes associated with aging through education and educational activities of various types.

The scientific monograph also includes our own research focused on overall health and selected lifestyle risk factors, especially consumption of various food groups, smoking, alcohol, physical activity and stress of participants at the University of the Third Age at Pavol Jozef Šafárik University in Košice, Slovak and foreign university students at the Medical Faculty of the Pavol Jozef Šafárik University in Košice. The scientific monograph is appropriate for the scientific community, students of medical and natural sciences, public health for all three degrees of university study.

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Pavol Joppa a kol.

University textbooks address the etiopathogenesis, clinical presentation, diagnosis, differential diagnosis, treatment, complications, and prognosis of the most significant non-specific respiratory diseases, including bronchial asthma, chronic obstructive pulmonary disease (COPD), pneumonias, pleural syndrome, lung cancer, interstitial lung diseases (including exogenous allergic alveolitis and sarcoidosis), and sleep apnea syndrome.

The final section on non-specific diseases discusses chronic cor pulmonale as the primary cardiovascular complication of chronic pulmonary diseases.

The last chapter focuses on the etiopathogenesis, diagnosis, treatment, and prevention of pulmonary and extrapulmonary forms of tuberculosis, addressing the scope of phthisiology

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Jozef Kafka

Behavior, in the slovak language expressed as an intention, belongs to basic mental processes of every individual. In this work I consider it as the basic component of an individual having two sides, outer- and inner side. I present it in the scheme No. 2.

The problem of behavior can not be fully covered, although there is a lot of writing, discussing and experimenting by ancient time.

The work may offer only few comments, approaching maily disorders of behavior. I present the original explanation of these disorders, dividing them on primary and derived ones. Primary disorders create the core of the disorder, derived disorders create a component of other disorders.

My classification of primary disorders is as follows:

1. age dependent disorders of behavior
2. disorders in the dynamical structure and in phases of behavior
3. integrative disorders of behavior, disorders of the will, which is the sign of the developed behavior of the individual.

The work is addresses to everone who is interested in his/her owm behavior, but especially for the Medical faculty and psychiatrists, for students of all our faculties.

Author 

E-book

Ivana Skoumalová - Zuzana Dankulincová

The publication entitled Competencies for clinical practice in the field of communication with the patient serves as the background and teaching material.

The text is structured to bring theoretical knowledge about the topic, current research findings in the field and practical tips for training skills in practice. It provides clear information on individual parts of the training and is designed to acquire knowledge that is the basis for practical skills in medical communication, especially in communication with patients.

It is intended for general and dental students to deepen their knowledge and acquire missing skills in medical communication, which are evidence-based and research-validated skills that have a demonstrable positive impact on patient communication.

Download the e-book for free  (pdf)

E-book

Adriana Boleková - Natália Hvizdošová (eds.)

Košický morfologický deň je každoročné májové stretnutie morfológov, ktorého sa zúčastňujú najmä košické morfologické pracoviská. Pri tejto príležitosti sa pravidelne vydáva zborník vedeckých prác. Tohoročný zborník je vydaný pri príležitosti 27. košického morfologického dňa. V zborníku autori prezentujú výsledky svojej vedecko-výskumnej a pedagogickej činnosti, ktoré majú charakter teoretických prehľadových štúdií a výskumných prác.

Download the e-book for free (pdf)

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Martina Čižmáriková - Peter Takáč 

It is known that pharmacology is a rapidly evolving medical field, with information about drug forms and their routes of administration constantly changing. In addition to the emergence of new drug forms, new trends are also observed in the routes of administration suitable for delivering drugs. Despite being significant factors influencing the efficacy and safety of pharmacotherapy – an indispensable component of comprehensive patient care – to our knowledge, there has been a lack of comprehensive and detailed textual material focused on this issue on the market. This fact is related to the broader scope of the professional text we are presenting, as rare drug forms or less commonly used routes of administration are only marginally mentioned or not mentioned at all in available pharmacology textbooks.

Our main goal was therefore to provide sufficient information about existing drug forms, their routes of administration, as well as their methods of delivery, which should serve to enhance the quality of pharmacotherapy in the context of so-called "tailored treatment," whose main effort is to individualize treatment for a specific patient. Although the work focuses on drug application methods, a detailed description of the technical implementation of algorithms and other related procedures is the subject of interest for other fields (nursing, surgical propaedeutics, etc.). Overall, it is a supplementary educational text provided in electronic form, which is extremely popular in today's modern informatized era. Thanks to this, the work can be used at any time at home or in a school environment, comprehensively or progressively, partially. We have also tried to enhance its quality by appropriate content organization, inclusion of practical experiences, as well as the inclusion of colorful images or photographs, overview tables, and appendices.

The textbook is supplemented by test quizzes serving to verify acquired selected knowledge, which are published on the website of the Department of Pharmacology at the Medical Faculty of UPJŠ in Košice (under "Teaching" → "Taught subjects"), and which will be continuously supplemented and updated (http://www.lf.upjs.sk/farmakologia/TEST%201.htm; http://www.lf.upjs.sk/farmakologia/TEST%202.htm).

Although the work is primarily intended for medical students, or students of pharmacy and other healthcare fields, we firmly believe that enriching information will be found in it by beginning graduates of these fields, as well as their teachers.

Download the e-book for free (pdf)

E-book

Štefan Tóth

Dyslipidemia is one of the main risk factors for the development of cardiovascular diseases. In recent years, extensive research has been conducted, leading to changes in therapeutic recommendations for dyslipidemia. These scripts aim to provide readers in the introductory chapters with information on the basic management of patients with dyslipidemia, procedures, target levels, and available medications and their combinations for achieving target levels, focusing on the practical aspect of dyslipidemia treatment. In the special section of the script, an overview is provided of the basic characteristics, studies of individual available hypolipemics, as well as hypolipemics that are not yet on our market or are still in the stage of clinical trials

Download the e-book for free  (pdf)