Textbook of practical physiology: part I - cardiovascular physiology

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Miriam Kozárová

The publication "News in Diabetology and Lipidology" focuses on extremely relevant topics in diabetology and lipidology, reflecting the state of these issues in light of the recommendations from professional societies from 2019. In diabetology, it primarily addresses the intensification of antidiabetic treatment using modern drug classes—specifically, incretin enhancers and sodium-glucose cotransporter-2 (SGLT-2) inhibitors (gliflozins). Few medical fields have experienced such a development of new pharmacological options as diabetology has in the last two decades. While pharmacotherapy for type 2 diabetes (DM2) was limited to the use of biguanides, sulfonylurea derivatives, and insulin throughout the second half of the last century, recent years have introduced entirely new groups of oral antidiabetics with cardio- and nephroprotective effects. In lipidology, it pertains to the new recommendations from the European Atherosclerosis Society (EAS) with new treatment goals for serum lipids and lipoproteins, including the use of biological therapies.

This textbook is primarily intended for medical students in doctoral studies and doctoral candidates, as well as for physicians preparing for specialization exams in internal medicine, endocrinology, diabetology, metabolic disorders and nutrition, as well as cardiology and angiology. I believe that readers will find information in this publication that will aid them in their studies and translate into their daily clinical practice.

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Ján Kučera - Eva Kovaľová - Juraj Strecha

Peri-implantation diseases such as peri-implantitis and mucositis have a wide range of prevalence. Several etiological factors and the interaction of risk factors influence their onset and development. Careful investigation determines the diagnosis and subsequent treatment. Treatment, depending on the condition, is either non-surgical or surgical. Systematic postoperative care, a recall system, and patient instruction and cooperation are essential, which create the preconditions for successful implant treatment.

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Želmíra Macejová

Vysokoškolský učebný text: “Vybrané kapitoly z reumatológie pre študentov lekárskych fakúlt“je určený na  pregraduálne štúdium pre študentov lekárskych fakúlt v študijnom odbore: všeobecné lekárstvo a zubné lekárstvo v rámci predmetu interná medicína 4. Kapitoly uvedené v danom diele zahŕňajú základy reumatológie, ktoré postačuje pre absolventa LF UPJŠ, zároveň slúži aj pre pregraduálnu prípravu v nelekárskom študijnom odbore – fyzioterapia.  Uvedené informácie sú základom pre prípravu na tzv. postupovú skúšku v rámci spoločného internistického kmeňa a zároveň podkladom aj pre špecializačné štúdium v odboroch všeobecný lekár a fyziatricko- rehabilitačný lekár. Text je rozdelený na  tieto časti:  vyšetrovacie metódy v reumatológii, terapeutické výkony v reumatológii,  autoimunitné ochorenia v reumatológii, kryštálmi indukované artritídy, infekčné artritídy, nezápalové reumatické ochorenia a metabolické ochorenia kostí. V závere je obrazová príloha k jednotlivým nozologickým jednotkám, ktoré sú podrobne opísané v texte.    

Michal Legiňa kol.

Progress in biology and medicine has always been significantly related to advances in physics. Not only has physics supplied instruments and methods of measurement that have led to many discoveries in physiology and medicine, but methods of physical research have changed many of the older approaches to the biologic sciences. Such circumstances have even led to development of a new scientific field: biophysics, which uses to a great extent physical instrumentation procedures applied to an experimental system. Because any instrument is an additional factor in any experimental system, it may affect the data. To interpret physical data on biological material correctly then, it is necessary to consider the characteristics of instrument response.

A practical course enables a student to acquire some skills, experience and methodological knowledge for performance of experiments and evaluation of measured data. Due to the fast development of instrumentation technology, it is not possible to teach every operation and procedure upon instruments we may use in a future. Besides the basic physical principles, the aim of a practical course is to point out some general rules and skills for instrument operation and for the interpretation of the measured values derived from such operation.

There are two kinds of lessons in practical courses. The first one focuses on laboratory measurements of some important physical quantities and the evaluation of the measured data. These measured quantities are components of the subject “medical biophysics” or of the phenomena studied. Experience provided in managing various scales and tables, as well as in the construction of tables and graphs is substantial. Lessons also enable students to repeat and to strengthen their knowledge of secondary school physics, which is useful for understanding of many phenomena studied in medical biophysics. The second kind of lesson provides experience with some of the diagnostic and therapeutic medical instruments, which can be seen in practical medicine.

The understanding of basic physical principles of corresponding instruments is both recommended and demanded. Theoretical preparation is not only an appropriate condition for the practical managing of the whole lesson, but also helps to avoid injury. This textbook, therefore, intends to help students in preparing for both the practical lessons and the final exam.

Authors

Mária Mareková a kol. 

Medical biochemistry is integral parts of basic theoretic knowledge of contemporary graduate at medical faculties. This textbook intends to help the undergraduate students of study branches General Medicine and Dental Medicine for the course of “Medical Biochemistry”. It is structured into 10 chapters concerning several topics: enzymology, cells membrane, metabolism, biochemistry of blood and organs, as well as some parts of clinical biochemistry.

The theoretical knowledge of this subject, which student obtains in the lectures, is verified in laboratory practices and is expanded in seminaries. Our selection of topics makes the text especially appropriate for medical students and managing of problems gives the students satisfactory ground for effective study of medical biochemistry and other related study subjects (e.g. clinical biochemistry, physiology, pathophysiology) in the sense of comprehension of relative continuity and interdependence of biochemical process or their function respectively.

Since the textbook brings only the skeleton survey on the biochemical problematic concerning medicine, students should broaden presented facts by additional study from lectures and/or from other sources. We expect this study literature to serve as a basic study material for mentioned medical study branches for preparation to written part of exam from “Medical Biochemistry”.

Authors

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Eva Ďurovcová - Mária Mareková

Clinical Biochemistry - selected chapters - MEFANET >>> 

After 7 years, we finally reworked the textbook on the subject of clinical biochemistry at UPJŠ FM in Košice. We have innovated information in accordance with recommendations of professional medical societies and added new chapters. As the scope of the subject is limited, the textbook does not cover all issues of biochemical diagnostics. It focuses on disorders of water-ion and acid-base balance disorders, and basic laboratory diagnostics of diseases of selected organs.

The textbook of clinical biochemistry has the ambition to become a practical aid for senior medical students and beginning doctors in the study of laboratory medicine. It should make it easier for them to orientate themselves in routinely used clinical-biochemical examinations and could form a springboard for a more detailed studying of laboratory methods and their use in diagnostic and monitoring algorithms.
Like any medical discipline, clinical biochemistry is evolving rapidly and gradually integrating with other areas of laboratory medicine. New diagnostic methods penetrate deeper into the essence of the biochemical mechanisms of the human body, and "omic" methods are gaining ground. It is almost sure that in a few years, laboratory examination looks quite different from today. If this publication quite hypothetically reaches its next edition, many chapters will need to updated, and new chapters written following the up-to-date status.
Authors thanks to their colleagues and reviewers for their professional comments and constructive criticism of the text - prof. Jaroslav Racek, MD, DrSc. from FM UK in Pilsen.
Authors thanks very kindly too prof. MUDr. Dušan Dobrota, CSc. (JFM UK Martin) and doc. MVDr. Zuzana Kostecká, PhD. (UVMP, Košice), who read and wrote review of this textbook.

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Marián Sabol - Helga Kostelná - Leonard Siegfried

Cieľom učebných textov je poskytnúť študentom medicíny a príbuzných odborov   poznatky o základných imunologických metódach, ktoré sa využívajú v klinickej praxi. V učebných textoch sú zahrnuté metódy na vyšetrenie fagocytózy, komplementu, imunoglobulínov, autoprotilátok,  HLA molekúl a T lymfocytov.  Súčasťou textov sú aj  postupy pre izoláciu a stanovenie počtu vybraných  typov buniek imunitného systému. Kombinácia klasických  metód (rozetové testy, fluorescenčná mikroskopia) a moderných metód   (napríklad prietoková cytometria a  ELISPOT) umožňuje orientáciu v základných laboratórnych metódach imunológie.

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Mária Rašiová

Cardiovascular diseases are among the main causes of morbidity and mortality in developed countries. Academic textbook: Selected Chapters from Angiology is devoted to the most common vascular diseases that the angiologist encounters on a daily basis.

Dilated artery diseases (abdominal aortic aneurysm), as well as stenotizing diseases of peripheral arteries, are described. Diseases such as deep vein thrombosis, thrombophlebitis and chronic venous insufficiency are discussed in the venous vascular system section. I also deal with the most common lymphatic vascular system disease ˗ lymphoedema.

In the individual chapters the risk factors of the diseases, symptoms and signs, diagnostics, treatment modalities (pharmacological therapy, endovascular therapy, angiosurgical therapy) and possible complications of the therapy are briefly analyzed.

My priority was to present the information in a logical, interesting and comprehensible form for students and for common clinical practice.

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Eva Slabá - Helena Mičková - Terézia Hudáková

Pomocné vysokoškolské učebné texty Praktické cvičenia z biológie a genetiky sú určené na praktické cvičenia z predmetov Biológia I. a Biológia II. pre študentov 1. roku štúdia v odbore všeobecné lekárstvo a Lekárska a humánna biológia I. a II., pre študentov 1. roku štúdia v odbore  zubné lekárstvo na Univerzite P. J. Šafárika v Košiciach - Lekárskej fakulte.

Andrea Madarasová Gecková - Daniela Husárová a kol.

The aim of this publication is to present the latest findings of the international study Health Behavior in School-aged Children (HBSC), regarding the health and health-related behavior of school-aged children in Slovakia.After four years, it again brings information on various topics covering physical and mental health, nutritional behavior, leisure-time activities, use of psychoactive substances, within social environment of school-aged children, including family, school and peers. The publication also presents newfindings connected to objectively measured physical fitness of these children. Finally, data about school-aged children with special educational needs are also presented.The findings play an important role in understanding the needs of the new generation of adolescents and are an important source of information for all those who work with them, not only professionals but also parents.Last but not least, they are also beneficial for all stakeholders and institutions who participate in the preparing of policies and strategies focused on supporting the health of school-aged children.

Jozef Firment a kol.

V predloženej učebnici si autori predsavzali zhrnúť informácie, ktoré pre úspešné absolvovanie predmetu Anestéziológia a intenzívna medicína považujú za esenciálne. Množstvo textu je stranovo limitované, preto si nemožno nárokovať na kompletnosť zhrnutej problematiky. Predpokladá sa, že študent na preukázanie vedomostí v študijnom predmete Anestéziológia a intenzívna medicína využije aj poznatky a skúsenosti nadobudnuté počas prednášok, praktických cvičení a samostatného štúdia iných dostupných zdrojov podľa zverejneného obsahu okruhov tém vyžadovaných na skúšku.

Jednotlivé kapitoly sú vybraté a zostavené tak, aby obsiahli štyri základné oblasti, ktoré sa vyučujú v rámci predmetu Anestéziológia a intenzívna medicína. Sú to: Anestéziológia, Intenzívna medicína, Liečba bolesti a Neodkladná starostlivosť.

Učebnica poskytuje základné informácie v odbore aj lekárom začínajúcim pracovať v odbore Anestéziológia a intenzívna medicína, lekárom pracujúcim v blízkych medicínskych odboroch, najmä chirurgických a v intenzívnej medicíne. Určite si však v nej nájdu zdroje mnohých informácií aj sestry pripravujúce sa na skúšku v postgraduálnom špecializačnom štúdiu v odbore Anestéziológia a intenzívna starostlivosť.

Ingrid Madárová - Lívia Barnišinová - Veronika Pálová

Táto učebnica je určená pre zahraničných študentov medicíny – začiatočníkov – ako slovenčina na špecifický účel výučby. Jej cieľom je pomôcť zahraničným študentom, ktorí (1) študujú medicínu (2) v cudzom jazyku (anglický jazyk) a (3) v zahraničí (Slovensko) zvládnuť výzvu pri príprave na praktickú časť ich štúdia – konverzácia s pacientom v Slovenskom jazyku.Zámerom je poskytnúť študentom krok za krokom najfrekventovanejšie slovné spojenia a výrazy potrebné pri komunikácii s pacientom. Lekcie sa zameriavajú hlavne na slovnú zásobu týkajúcu sa častí ľudského tela a na základné symptómy a príznaky chorôb.Dôraz je kladený na krátke dialógy medzi lekárom a pacientom. Pri precvičovaní dialógov sú študenti vedení k nácviku komunikácie so zreteľom na porozumenie, bez prípadných obáv o gramatickú správnosť. Gramatické javy sú predstavované postupne, cez jednoduché  pomôcky – „tipy“.V prípade potreby si môžu študenti nájsť a doplniť si „chýbajúce časti gramatiky“ prostredníctvom odkazov na odporúčanú literatúru. Cieľom tejto knihy je uľahčiť a zefektívniť celý proces štúdia/osvojenia si (lekárskej) slovenčiny.

H.Mičková - V.Habalová - J.Židzik - E.Slabá

 Eva Ďurovcová - Mária Mareková 

The presented textbook is intended for students of general medicine and should support their knowledge about indication and interpretation of basic biochemical tests. Clinical biochemistry continues to be one of the most rapidly advancing areas of laboratory medicine, which in line with using of modern technology more and more emphasizes the evidence-based medicine in order to improve diagnosis and monitoring of patients. Selected topics have an ambition to outline and explain the most common issues of biochemical diagnosis of in internal medicine. Individual chapters are devoted to disorders of water, electrolyte and acid-base balance, kidney and liver disease, diabetes mellitus, and biomarkers used in the diagnosis of cardiac necrosis and heart failure. Given the limited range, the textbook merely summarizes the basic knowledge that students have obtained during the study of other subjects, such as medical biochemistry, pathophysiology and internal medicine, and emphasis is given to laboratory diagnosis in accordance with the newer guidelines of professional societies. We hope that the textbook will be helpful in the study of clinical subjects and encourage students' interest in laboratory medicine.

Authors

Janette Baloghová

Všeobecná dermatovenerológia je nosnou časťou dermatovenerológie. Morfológia, popis a charakteristika jednotlivých eflorescencií sú kľúčové v diagnostike a diferenciácii kožných ochorení spolu s dobre odobratou anamnézou. Snahou bolo vytvoriť vysokoškolský učebný text, ktorý tvorí praktický návod ako vyšetrovať pacienta s kožným ochorením. Cieľom jednotlivých kapitol je dokonale si osvojiť dermatologickú terminológiu, fyzikálnym vyšetrením vnímať špeciálne kožné znaky a zmeny, vedieť sa orientovať v algoritme pomocných vyšetrovacích metód a testov a pochopiť rozdielne vlastnosti a charakteristiku kože vzhľadom na vek pacienta, vznik, priebeh a trvanie kožných prejavov. Posledná kapitola predstavuje praktickú topografiu kožných ochorení v tabuľkách. Dermatovenerológia patrí k interdisciplinárnym odborom, preto všeobecná dermatológia bude určite dobrým sprievodcom pri diagnostike kožných ochorení nielen študentov medicíny, ale aj lekárov prvého kontaktu a styčných odborov.

 Kvetoslava Rimárová 

The theme of the presented university textbook is a summary of selected basic knowledge of hygiene - environmental medicine. The script includes significant areas of environmental medicine as a science: the basics of environmental medicine, health and prevention issues of environmental health and risk assessment of potential exposure, the issue of air pollution, indoor pollution, problems of drinking water, the action of soil and solid waste, further issue of housing, nutrition and the impact of working conditions on health. Nutritional factors textbooks dealing with issues of rational nutrition, describe the individual components of nutrition, but also address the issue of food hygiene and the possibilities of foodborne infections. One chapter is also devoted to the impact of environmental conditions on health of children and youth. 

University textbook as a manuscript consists from 199 manuscript pages, is divided into 12 basic chapters, contains 36 citations in the literature.  In the Preface, the issue of categorization of diseases and define the basic concepts of health, prevention. Other chapters deal with the above selected chapters hygiene.

This university textbook comes as a basic university textbook for students of general  medicine in the English language, for students of bachelor's and master's studies  of medical schools - mainly bachelor's and master' program of  "Public health". Students of medicine and dentistry can also use these textbooks as an educational tool in the study of other subjects in the teaching of public health.

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