Chemistry - Sample Questions for Entrance Exam

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Erik Dosedla

A uterine scar is currently a significant medical problem. Uterine scars most commonly occur after a Cesarean section, which is one of the most frequent laparotomic surgeries (Yazicioglu et al., 2006). The frequency of Cesarean sections increased between 1990 and 2014 in the USA from 21.2% to 32.2% (Hamilton et al., 2015), in Great Britain from 12% to 26.2% (NHS Maternity Statistics - England, 2013-14: Summary Report, 2015), and in the Slovak Republic from 8.7% to 31% (Národné centrum zdravotníckych informácii, 2016).

After a Cesarean section (CS), there is a risk of abnormal healing of the uterotomic wound, which can result in the development of certain pathological conditions in consecutive pregnancies (uterine rupture, ectopic pregnancy in the Cesarean scar, placental disorders) (Seow et al., 2004; Oyelese and Smulian, 2006; Fitzpatrick et al., 2012). In addition, a defect in the Cesarean scar is associated with chronic dysmenorrhea, chronic pelvic pain, infertility, and postmenstrual spotting (Wang et al., 2009; Bij de Vaate et al., 2011).

Ultrasound is a valuable examination method in the diagnostic and therapeutic management of these pathological conditions.

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Pavol Joppa a kol.

University textbooks address the etiopathogenesis, clinical presentation, diagnosis, differential diagnosis, treatment, complications, and prognosis of the most significant non-specific respiratory diseases, including bronchial asthma, chronic obstructive pulmonary disease (COPD), pneumonias, pleural syndrome, lung cancer, interstitial lung diseases (including exogenous allergic alveolitis and sarcoidosis), and sleep apnea syndrome.

The final section on non-specific diseases discusses chronic cor pulmonale as the primary cardiovascular complication of chronic pulmonary diseases.

The last chapter focuses on the etiopathogenesis, diagnosis, treatment, and prevention of pulmonary and extrapulmonary forms of tuberculosis, addressing the scope of phthisiology

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I. R. Mavlyanov - A. K. Ashirmetov - Z. I. Mavlyanov - G. J. Jarilkasinova

Need of carrying out a pharmacological genotyping for providing the individualized pharmacotherapy is shown in the monograph based on the analysis of own and literary data of the central link of drug pharmacokinetics– systems of cytochrome P-450, taking into account its genetic polymorphysm.
The monograph is intended for the clinical pharmacologists, geneticists and experts dealing with this problem.

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Silvia Farkašová Iannaccone

Forensic medicine is a fundamental medical discipline that deals with determining the cause of death in cases of violent and non-violent deaths, as well as investigating and assessing the effects of violence on the human body, including in cases involving living persons. This textbook provides a comprehensive and complex overview of the basic tasks and theoretical knowledge of forensic medicine. Its aim is to provide a theoretical basis in the form of images of morphological autopsy findings for the study of the compulsory subject Forensic Medicine and Medical Law in the study programs General Medicine and Dentistry. The author emphasizes the need to know the basics of forensic medicine in every medical field and to take a multidisciplinary approach when clarifying medical-legal issues.

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Eva Szabóová

The publication "Fundamentals of Cardiovascular Risk Assessment: Tools and Applications" is the first of its kind in Slovakia. It was created with the aim of providing healthcare professionals, medical students, and anyone interested in the subject with a clear, practical overview of cardiovascular risk. The book presents a global and national picture of mortality, emphasizes the importance of prevention and screening, and introduces the basic principles of risk assessment. Special attention is paid to risk factors and modifiers that can significantly change a patient's prognosis. For a better understanding of the issue, the reader will also find chapters devoted to clinical conditions, an overview of scoring systems, risk categories, and finally practical examples from clinical practice that link theory with everyday medical reality. Our goal is for this book to be not only an educational tool, but also a practical guide for decision-making in clinical practice. We believe that it will contribute to a better understanding of the complexity of cardiovascular risk and at the same time help to strengthen the emphasis on prevention, which remains the most effective tool in the fight against these diseases.

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Mária Sováriová Soósová a kol.

The proposed university textbook provides knowledge in the field of nursing in internal medicine. It is intended primarily for students of the nursing program, but also for nurses working in this specialization. The textbook builds on the previous two parts: Nursing Process in Internal Medicine I (Sováriová Soósová, 2006) and Nursing Process in Internal Medicine II (Suchanová, 2007). It is divided into four chapters, focusing on disorders of water and electrolyte balance and acid-base equilibrium, kidney and urinary tract diseases, endocrine system diseases, and musculoskeletal disorders.

Each chapter is similarly structured, beginning with diagnostic methods commonly used in the respective area. Subsequent subchapters address nursing care for selected diseases of specific bodily systems. Each subchapter consists of a clinical introduction (characteristics of the disease, its etiology, clinical presentation, diagnosis, and treatment) and nursing care for the given disease. This includes assessment, formulation of nursing diagnoses, and planning nursing care (setting goals, outcome criteria, and planning possible interventions).

The textbook serves as a model framework and algorithm for managing nursing care using the nursing process method.

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Marek Šoltés - Jozef Radoňak

Laparoscopic surgery today represents the standard and, in many respects, a preferred modality of surgical treatment. The dynamics of its global expansion, enabled by advancements in biomedical technologies and the development of global information and communication channels, is unprecedented in the history of surgery. Currently, there is virtually no abdominal operation that is not performed laparoscopically, with laparoscopic procedures often being the method of choice.

Despite—or perhaps because of—the unprecedentedly rapid penetration of laparoscopic surgeries into everyday surgical practice, universally accepted technical standards are still lacking in many respects. The high variability of procedural approaches within individual laparoscopic operations stems more from the traditions of specific workplaces than from evidence-based medicine. This situation is further influenced by the development of new and revived concepts such as mini-laparoscopy, SILS (Single Incision Laparoscopic Surgery), NOTES (Natural Orifice Transluminal Endoscopic Surgery), and their hybrid combinations with classical laparoscopy.

The aim of this monograph is to draw the attention of the professional community back to the fundamental principles of laparoscopic surgery, which should serve as a foundation for the effective and safe performance of laparoscopic operations, as well as a basis for a critical stance towards fashionable innovative trends.

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Nikita Bobrov et al.

History of ethics represents a search for basic principle, which would enable a distinction between moral and immoral, good and bad, right and wrong. The main problem lies in motives, methods and consequences of human conduct. The integrity of medical profession puts emphasis on life-long study and practice according to the professional competence, and last but not least on ethical principles and rules of medical ethics.
Medical ethics, as a part of bioethics, is currently taking on a huge importance in everyday clinical practice and must face many serious ethical issues regarding the whole system of health care. On general level the decision-making in medical practice is quite easy, based on the requirement to always act in the patient's best interest. However, it is often difficult to know exactly what is best for the patient, in a certain situation, for this particular patient. Also with each progress in medicine and its globalization, the more aspects of human lives are being affected.

Biomedical research, and the new treatment and diagnostic methods it provides are viewed differently in each country, therefore various cultural, religious, social and legal aspects must be considered in their assessment, as well as the basic principles of medical ethics. Worldwide effort on unifying ethical regulations on certain aspects of health care led to the establishment of many legally recognized documents the doctors must be familiar with.

Teaching ethics to students of medical school aims to educate the future doctors towards ethical decision-making, behaviour and professional conduct according to the basic principles of medical ethics.
This textbook provides the basic information on medical ethics for students of medical faculties and serves as a practical introduction to the most common ethical problems of health care provision for their future professional practise.

Authors

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 Ingrid Dravecká 

College textbook "Investigation methods in Diabetology" is designed for students of medicine. It can help them in preparing for an exam from internal medicine but specially in preparing for a state exam from internal medicine. The introduction is devoted to classification and diagnostic criteria of diabetes mellitus. Further It describes investigation options (clinical, laboratory, imaging) of different types of diabetes mellitus as well as its acute and chronic complications. At the end there are given diagnostics and classification of the individual components of the metabolic syndrome, obesity and dyslipidemia.

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Roman Beňačka  a kolektív

Obsahovo i formou nová učebnica všeobecnej patofyziológie v slovenskom jazyku pre štúdium predmetu Patologická fyziológia pre odbor Všeobecné lekrástvo na lekárskych fakultách na Slovensku resp. v zahraniční. Nadväzuje na pedagogické skúsenosti s výučbou klasickej a molekulárnej patofyziológie a tradíciu vysokoškolských učebníc vydávaných Ústavom patofyziológie Lekárskej fakulty v Košiciach (prvá slovenská učebnica i učebnica Všeobecnej patofyziológie). Učebnica popisuje všetky základné témy z nozológie, etiológie a patogenzéy, ktoré sú tradične  predmetom výučby patofyziológie na lekárskych fakultách v európskom priestore. Prináša najnovšie poznatky štýlom i obsahovo v priamej konfrontácii s obdobnou cudzojazyčnou literatúrou a tp v čitateľsky rovnako atraktívnej prezentačnej forme s početnými obrázkami a tabuľkami.

Michal Legiňa kol.

Progress in biology and medicine has always been significantly related to advances in physics. Not only has physics supplied instruments and methods of measurement that have led to many discoveries in physiology and medicine, but methods of physical research have changed many of the older approaches to the biologic sciences. Such circumstances have even led to development of a new scientific field: biophysics, which uses to a great extent physical instrumentation procedures applied to an experimental system. Because any instrument is an additional factor in any experimental system, it may affect the data. To interpret physical data on biological material correctly then, it is necessary to consider the characteristics of instrument response.

A practical course enables a student to acquire some skills, experience and methodological knowledge for performance of experiments and evaluation of measured data. Due to the fast development of instrumentation technology, it is not possible to teach every operation and procedure upon instruments we may use in a future. Besides the basic physical principles, the aim of a practical course is to point out some general rules and skills for instrument operation and for the interpretation of the measured values derived from such operation.

There are two kinds of lessons in practical courses. The first one focuses on laboratory measurements of some important physical quantities and the evaluation of the measured data. These measured quantities are components of the subject “medical biophysics” or of the phenomena studied. Experience provided in managing various scales and tables, as well as in the construction of tables and graphs is substantial. Lessons also enable students to repeat and to strengthen their knowledge of secondary school physics, which is useful for understanding of many phenomena studied in medical biophysics. The second kind of lesson provides experience with some of the diagnostic and therapeutic medical instruments, which can be seen in practical medicine.

The understanding of basic physical principles of corresponding instruments is both recommended and demanded. Theoretical preparation is not only an appropriate condition for the practical managing of the whole lesson, but also helps to avoid injury. This textbook, therefore, intends to help students in preparing for both the practical lessons and the final exam.

Authors

 Helena Mičková a kol. 

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Marianna Vitková

Current classification of demyelinating diseases of the central nervous system according to van der Knaap and Valko from 2005 includes 97 congenital and acquired diseases that cause demyelination of the white matter of the brain and spinal cord. Most of these disorders lacks any definitive diagnostic test, so the accurate diagnosis depends on upon clinical symptoms, course of the disease, neurological findings, and the results of neuroimaging and laboratory examinations.

The aim of this textbook is to provide an accurate overview of acquired demyelinating diseases of the CNS, their etiopathogenesis, clinical picture and diagnostic options.

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Tatiana Kimáková - Štefan Tóth - Ivan Uher

The scientific monograph is devoted to active and healthy aging, its basic indicators, involutional changes, or the relationship between healthy aging and lifestyle. Adopting a healthy lifestyle and actively participating in health care for yourself are important elements in all stages of our lives, and therefore in healthy aging. We describe the possibilities of older people to slow down the adverse changes associated with aging through education and educational activities of various types.

The scientific monograph also includes our own research focused on overall health and selected lifestyle risk factors, especially consumption of various food groups, smoking, alcohol, physical activity and stress of participants at the University of the Third Age at Pavol Jozef Šafárik University in Košice, Slovak and foreign university students at the Medical Faculty of the Pavol Jozef Šafárik University in Košice. The scientific monograph is appropriate for the scientific community, students of medical and natural sciences, public health for all three degrees of university study.

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Pavol Jarčuška - Daniel Pella - Ján Rosocha (eds.)

Proceedings of lectures from thematic conferences organized by UVP MediPark

UVP Medipark – the path to innovation in research, diagnostics, and treatment – was the title of the conference held on Tuesday, May 29, 2018, at the premises of the Faculty of Medicine, Pavol Jozef Šafárik University in Košice. The patronage of the event was taken over by the rector of UPJŠ, Prof. RNDr. Pavol Sovák, CSc. The conference program was divided into two main areas – Innovative scientific technologies, clinical research, and the path to the development of new drugs, and UVP Medipark – main research areas.

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Marek Šoltés - Jozef Radoňak

Laparoskopická chirurgia dnes predstavuje štandardnú a v mnohých ohľadoch preferovanú modalitu chirurgickej liečby. Dynamika jej celosvetového rozšírenia, umožnená pokrokom v biomedicínskych technológiách a rozvojom globálnych informačných a komunikačných kanálov, nemá v histórii chirurgie obdobu. V súčasnosti už prakticky neexistuje žiadna brušná operácia, ktorá by sa nevykonávala laparoskopickým spôsobom, pričom v mnohých prípadoch je už laparoskopický postup metódou voľby.

Napriek, a možno práve vďaka bezprecedentne rýchlej penetrácii laparoskopických operácií do každodennej chirurgickej praxe naďalej v mnohých ohľadoch absentujú všeobecne akceptované technické štandardy. Vysoká variabilita procesných postupov v rámci jednotlivých laparoskopických operácií vychádza skôr zo zvyklostí daného pracoviska ako z medicíny založenej na dôkazoch. Táto situácia je ďalej modifi kovaná rozvojom nových a staronových koncepcií charakteru minilaparoskopie, SILS či NOTES a ich hybridných kombinácií s klasickou laparoskopiou.

Cieľom monografi e je pritiahnuť pozornosť odbornej verejnosti späť k základným princípom laparoskopickej chirurgie, ktoré by mali byť základňou pre efektívne a bezpečné vykonávanie laparoskopických operácií, ako aj bázou pre kritický postoj k módnym inovatívnym trendom. Obsahovo sa sústredí skôr na všeobecne menej známe a v našich podmienkach zriedkavo diskutované témy, ktorých význam sa hlbšie analyzoval len v nedávnej minulosti. Našou ambíciou bolo vytvoriť vyvážený materiál, ktorý by bol zaujímavým primárnym informačným zdrojom nielen pre lekárov špecialistov, ale aj pre poslucháčov lekárskych fakúlt a kolegov v špecializačnej príprave v chirurgických odboroch.

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