XXIII. slovensko - český kongres o infekčných chorobách

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Ladislav Kočan-Dušan Rybár-Róbert Rapčan

The autonomic nervous system is a vital component of the peripheral nervous system, responsible for maintaining homeostasis and regulating internal processes within the body. Unlike the voluntary control exerted by the central nervous system, the autonomic nervous system operates involuntarily, innervating smooth organs, vessels, skin glands, and even exerting some influence over skeletal muscles in connection with vegetative functions such as breathing, digestion, and the urinary and gonadal systems. Its impact extends crucially to the cardiac muscles of the heart and plays a significant role in endocrine and metabolic functions, thermoregulation, as well as emotional and behavioral responses, including adaptive reactions to stressors. The aim of this publication is to provide a comprehensive and objective exploration of the anatomical and physiological intricacies of the autonomic nervous system, offering insights into its clinical applications. Within these pages, we meticulously delineate various interventional therapeutic procedures tailored to specific diagnoses related to the autonomic nervous system, aligning each intervention with the anatomical framework of the autonomic system. The efficacy of these procedures is evaluated based on the level of evidence, as per the current recommendations of Evidence-Based Medicine. This publication is primarily crafted for fifth and sixth-year medical students and medical professionals specializing in anesthesiology, intensive care, and pain medicine. It serves as a valuable resource for gaining a deeper understanding of autonomic nervous system function and its clinical implications, facilitating informed decision-making in clinical practice.

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Iveta Cimbolákováa kol.

The premise “today’s research shapes the healthcare of tomorrow” expresses the importance of medical research and the reason for its pursuit. Scientific research and advances in biomedical sciences, as well as their application in medical practice and in the process of delivering healthcare, nevertheless bring new problems in the area of ethics.

Biomedical research itself requires the precise definition of hypotheses, which are tested both under laboratory conditions and on experimental animals. Although clinical studies on human subjects are expected to benefit individual participants and to advance fundamental biomedical knowledge, they also entail certain risks depending on the nature of the research. These risks must be minimized, and the experiment should be conducted freely while also taking place within specific measures to protect all involved-not only the test subjects, but also the researchers themselves.

The presented publication provides an overview of the general conditions and ethical principles of research involving laboratory animals and human subjects, the issue of professional and ethical assessment of projects, as well as fraud and the publication of results. At present, we are witnessing tremendous progress in molecular biological sciences, which brings ethical dilemmas also in the field of genetics. For this reason, one of the chapters is devoted to the latest findings in this area.

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Libuša Tirpáková a kol. 

Primary care is the first level of the health system where people come with their health problems and where the health promotion and preventive care treatments and needs of the majority of the population are implemented.

The university textbook, which is organized in nine chapters, offers an overview of general outpatient health care from a nursing perspective. It characterizes the nursing process in ambulatory health care and models of nursing care. It addresses the implementation of advanced practice nursing in ambulatory health care and the role of the nurse in prevention and health promotion.

The textbook is intended for nursing students in both undergraduate and postgraduate education, as well as those interested in other health professions.

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Denisa Harvanová (ed.)

The proceedings contain abstracts submitted by participants of the international scientific event entitled "MVDr. Ján Rosocha, CSc. Memorial" (3rd year). The event is part of a bilateral project named: "Extracellular vesicles: a promising cell-free therapy for cartilage repair (SK-AT-23-0005)", which is implemented within the framework of cooperation between Pavol Jozef Šafárik University in Košice, Slovakia, and the University for Continuing Education Krems in Austria. It is funded by the Slovak Research and Development Agency (APVV) under the bilateral call Slovakia-Austria 2023 and by OEAD – Agency for Education and Internationalisation under the project number SK11/2024. The MVDr. Ján Rosocha, CSc. Memorial (3rd year) was held on October 14, 2025, on the premises of the Faculty of Medicine, P. J. Šafárik University in Košice, Slovak Republic.

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Pavol Joppa a kol.

University textbooks address the etiopathogenesis, clinical presentation, diagnosis, differential diagnosis, treatment, complications, and prognosis of the most significant non-specific respiratory diseases, including bronchial asthma, chronic obstructive pulmonary disease (COPD), pneumonias, pleural syndrome, lung cancer, interstitial lung diseases (including exogenous allergic alveolitis and sarcoidosis), and sleep apnea syndrome.

The final section on non-specific diseases discusses chronic cor pulmonale as the primary cardiovascular complication of chronic pulmonary diseases.

The last chapter focuses on the etiopathogenesis, diagnosis, treatment, and prevention of pulmonary and extrapulmonary forms of tuberculosis, addressing the scope of phthisiology

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Helena Mičková -  Jozef Židzik -  Mária Mareková - Marek Stupák - 

Peter Urban

Modelové otázky na prijímacie skúšky pre bakalárske štúdium sú určené záujemcom o bakalárske študijné programy na Univerzite Pavla Jozefa Šafárika v Košiciach, Lekárskej fakulte. Publikácia obsahuje 500 otázok z biológie a 500 otázok z chémie, ktoré tvoria podklady písomných testov na prijímacie skúšky. Otázky na prijímacích skúškach však nemusia presne kopírovať modelové otázky. Testy z chémie a biológie pokrývajú tie okruhy učiva z predmetov biológia a chémia na slovenských gymnáziách, vedomosti z ktorých sú vyžadované od poslucháčov bakalárskych študijných smerov (napr. ošetrovateľstvo, fyzioterapia, verejné zdravotníctvo). Otázky z biológie a z chémie sú predkladané v dvoch samostatných celkoch. Odpovede na otázky sú riešené formou ponúkaných variantných odpovedí, obsahujúcich správne aj nesprávne možnosti. Správne odpovede sú vyznačené v kľúči na konci publikácie.

Príklady z chémie tvoria zvláštnu časť, v ktorej nie sú ponúkané variantné odpovede. Pre lepšiu kontrolu správnosti výpočtu je v zátvorke uvedený jeden správny výsledok (z viacerých možných – líšiacich sa napr. v jednotkách – gramy, miligramy, móly). Autori publikácie sa snažili minimalizovať možné chyby v texte a vyhnúť sa nejednoznačným formuláciám otázok a odpovedí. Modelové otázky sú okrem prípravy na prijímacie skúšky na UPJŠ LF v Košiciach vhodné aj na zopakovanie gymnaziálneho učiva z biológie a chémie pred maturitnou skúškou.

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I. R. Mavlyanov - A. K. Ashirmetov - Z. I. Mavlyanov - G. J. Jarilkasinova

Need of carrying out a pharmacological genotyping for providing the individualized pharmacotherapy is shown in the monograph based on the analysis of own and literary data of the central link of drug pharmacokinetics– systems of cytochrome P-450, taking into account its genetic polymorphysm.
The monograph is intended for the clinical pharmacologists, geneticists and experts dealing with this problem.

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Libuša Tirpáková - Mária Sováriová Soósová a kol.

It is expected that nurses and professionals working in healthcare will be able to perform various specialized procedures, or assist with selected procedures, skillfully, confidently, and safely.

The university textbook of Nursing Techniques guides students through the most commonly performed nursing activities, reflecting the latest knowledge from the profession, evidence-based practice, and professional guidelines. A significant aspect of this publication is its emphasis on patient individuality and involvement in the planning and implementation of procedures, as well as the prevention of complications and the consistent performance of nursing interventions in accordance with the latest professional and scientific knowledge.

The textbook is divided into twelve chapters. In the introductory chapters, the authors address the organization of the nursing unit and infection control in healthcare facilities. Further chapters are devoted to patient assessment, especially vital functions, nutritional care, preparation and administration of various forms of medication, collection of biological material, care of urinary and bowel elimination, nurse assistance during punctures, wound care, and electrocardiographic examination.

The main aim is to address primarily nursing students, but also students of general and dental medicine and selected healthcare disciplines. We believe that both students and professionals will find in this textbook a guide and a practical assistant.

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Nikita Bobrov et al.

History of ethics represents a search for basic principle, which would enable a distinction between moral and immoral, good and bad, right and wrong. The main problem lies in motives, methods and consequences of human conduct. The integrity of medical profession puts emphasis on life-long study and practice according to the professional competence, and last but not least on ethical principles and rules of medical ethics.
Medical ethics, as a part of bioethics, is currently taking on a huge importance in everyday clinical practice and must face many serious ethical issues regarding the whole system of health care. On general level the decision-making in medical practice is quite easy, based on the requirement to always act in the patient's best interest. However, it is often difficult to know exactly what is best for the patient, in a certain situation, for this particular patient. Also with each progress in medicine and its globalization, the more aspects of human lives are being affected.

Biomedical research, and the new treatment and diagnostic methods it provides are viewed differently in each country, therefore various cultural, religious, social and legal aspects must be considered in their assessment, as well as the basic principles of medical ethics. Worldwide effort on unifying ethical regulations on certain aspects of health care led to the establishment of many legally recognized documents the doctors must be familiar with.

Teaching ethics to students of medical school aims to educate the future doctors towards ethical decision-making, behaviour and professional conduct according to the basic principles of medical ethics.
This textbook provides the basic information on medical ethics for students of medical faculties and serves as a practical introduction to the most common ethical problems of health care provision for their future professional practise.

Authors

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Katarína Tokarčíková

The university textbook entitled "Vasculitis" provides a systematic overview of vasculitis encountered in clinical practice. The text is supplemented with tables reflecting the latest recommendations of professional societies and illustrations that aid in understanding the subject matter. The individual chapters analyze the etiopathogenesis of individual types of vasculitis, their epidemiology, clinical symptoms, diagnosis, differential diagnosis, treatment, prognosis and also prevention and screening options. The publication is intended for doctoral students at medical faculties, but it can also be used by doctors in specialist training in internal medicine, angiology, cardiology, rheumatology, nephrology and general medicine.

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Martina Zavacká a kolektív

Kniha „DIABETICKÁ NOHA Z POHĽADU CIEVNEHO CHIRURGA“ obsahuje 14 kapitol. Pojednáva o syndróme diabetickej nohy z multidisciplinárneho pohľadu viacerých odborníkov: angiochirurga, diabetológa, chirurga, podiatra, röntgenológa, neurológa a algeziológa. Úvodné kapitoly majú charakter propedeutiky, čo má taktiež význam aj pre pregraduálnu výchovu. Nasledujúce kapitoly sa zaoberajú vznikom syndrómu, výskytom, jeho diagnostikou, terapeutickými postupmi, pridruženými postihnutiami neurologického charakteru, starostlivosťou podiatra a algeziológa pri pretrvávaní bolestí. Ďalšie časti sú vyhradené chirurgickej a endovaskulárnej liečbe tepien cestou cievneho chirurga a intervenčných angiológov. Nezabúdajúc na problematiku amputácií a správnu rehabilitáciu pacientov s diabetom.  V knihe nájdu poučenie cievni chirurgovia, angiológovia, všeobecní chirurgovia, diabetológovia, neurológia, röntgenológovia, podiatri  a všeobecní lekári.

Kniha je zdrojom najnovších teoretických i praktických informácií pre postgraduálnu výchovu vyššie spomenutých odborníkov.

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Terézia Kisková - Stanislav Matéffy - Františka Horváthová

The laboratory rat (Rattus norvegicus) is one of the most commonly used experimental animals. It serves as a model organism for analyzing numerous biological processes and pathological mechanisms, such as cardiovascular diseases, metabolic disorders (e.g., lipid metabolism, diabetes mellitus), neurological and neuropsychiatric conditions (e.g., stroke, epilepsy, or Alzheimer's disease), neurobehavioral research, autoimmune diseases (e.g., arthritis), cancer, and renal diseases. It offers many unique advantages for modeling human diseases, testing drugs and natural substances, and studying responses to environmental factors. The size of the laboratory rat, compared to the mouse, creates ideal conditions for physiological manipulations. Additionally, rats are used in clinical toxicology to test chemical substances (Hedrich, 2000).

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Erik Dosedla

A uterine scar is currently a significant medical problem. Uterine scars most commonly occur after a Cesarean section, which is one of the most frequent laparotomic surgeries (Yazicioglu et al., 2006). The frequency of Cesarean sections increased between 1990 and 2014 in the USA from 21.2% to 32.2% (Hamilton et al., 2015), in Great Britain from 12% to 26.2% (NHS Maternity Statistics - England, 2013-14: Summary Report, 2015), and in the Slovak Republic from 8.7% to 31% (Národné centrum zdravotníckych informácii, 2016).

After a Cesarean section (CS), there is a risk of abnormal healing of the uterotomic wound, which can result in the development of certain pathological conditions in consecutive pregnancies (uterine rupture, ectopic pregnancy in the Cesarean scar, placental disorders) (Seow et al., 2004; Oyelese and Smulian, 2006; Fitzpatrick et al., 2012). In addition, a defect in the Cesarean scar is associated with chronic dysmenorrhea, chronic pelvic pain, infertility, and postmenstrual spotting (Wang et al., 2009; Bij de Vaate et al., 2011).

Ultrasound is a valuable examination method in the diagnostic and therapeutic management of these pathological conditions.

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Adriana Boleková (ed.)

Proceedings of Scientific Works

The Košice Morphological Day is an annual May meeting of morphologists, primarily attended by Košice morphological workplaces. On this occasion, a collection of scientific works is regularly published.

This year's collection was published on the occasion of the 23rd Košice Morphological Day, which did not take place due to the poor epidemiological situation.

In the collection, the authors present the results of their scientific-research and pedagogical activities, which are in the form of theoretical overview studies and research works.

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Tatiana Kimáková

Táto vedecká monografia je komplexnou vedeckou prácou zameranou na prítomnosť a pôsobenie ortuti v životnom prostredí, ale aj na rizikové faktory zdravia, ktoré sú s ňou spojené. Monografia predstavuje charakteristiku ortuti v multidisciplinárnom zábere, prezentuje využitie v priemysle a v zdravotníctve, popisuje negatívne vplyvy ortuti v životnom prostredí, na zdravotný stav obyvateľstva. Zároveň prináša návrhy a odporúčania pre rizikové skupiny ľudí. Súčasťou monografie je komplexný výskum koncentrácie ortuti vo vzorkách komodít domácej i zahraničnej produkcie a vo vzorkách rastlín pomocou atómového absorpčného spektrometra AMA 254. Vedecká monografia je vhodná pre vedeckú komunitu, študentov medicínskych, veterinárnych, prírodovedných a poľnohospodárskych odborov ako aj pre študentov verejného zdravotníctva všetkých troch stupňov vysokoškolského štúdia. Monografia je učená aj pre všetkých záujemcov z radov informovanej verejnosti.

Autorka