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E-publication

Beáta Grešš HalászMária Sováriová SoósováMartin ČervenýJana Michalková

The aim of this university textbook is to provide a systematically structured teaching text focused on research in health sciences and, at the same time, to offer a practical methodological manual for writing final theses intended for students of medical and non-medical fields of study. The first chapter introduces the topic, maps the historical development of research in medical and non-medical sciences, and explains the concept of evidence-based practice (EBP) in the context of research activities. It also highlights the importance of research for these fields and describes the individual steps, principles, and methodological procedures of scientific work. The second chapter focuses on the basic attributes of research in health sciences, with an emphasis on key definitions, basic research designs, the typology of scientific studies, and the possibilities for using the relevant methodologies. It also includes the interpretation and analytical processing of quantitative data, while the third chapter analogously elaborates on the qualitative research approach. The fourth chapter is devoted to the ethical aspects of scientific research. The fifth chapter focuses on the evaluation of research papers in terms of their quality, structure, content coherence, reliability, and validity. The final sixth chapter provides methodological guidelines for planning, implementing, and processing individual types of final theses, with the aim of offering students practical and clearly structured instructions for their preparation. The publication also includes questions, tasks, and exercises that supplement theoretical knowledge with practical examples. These cases are intended to develop students' ability to design research studies and methodologically correctly prepare final theses.

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E-book

Iveta Cimbolákováa kol.

The premise “today’s research shapes the healthcare of tomorrow” expresses the importance of medical research and the reason for its pursuit. Scientific research and advances in biomedical sciences, as well as their application in medical practice and in the process of delivering healthcare, nevertheless bring new problems in the area of ethics.

Biomedical research itself requires the precise definition of hypotheses, which are tested both under laboratory conditions and on experimental animals. Although clinical studies on human subjects are expected to benefit individual participants and to advance fundamental biomedical knowledge, they also entail certain risks depending on the nature of the research. These risks must be minimized, and the experiment should be conducted freely while also taking place within specific measures to protect all involved-not only the test subjects, but also the researchers themselves.

The presented publication provides an overview of the general conditions and ethical principles of research involving laboratory animals and human subjects, the issue of professional and ethical assessment of projects, as well as fraud and the publication of results. At present, we are witnessing tremendous progress in molecular biological sciences, which brings ethical dilemmas also in the field of genetics. For this reason, one of the chapters is devoted to the latest findings in this area.

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E-book

Terézia Kisková - Stanislav Matéffy - Františka Horváthová

The laboratory rat (Rattus norvegicus) is one of the most commonly used experimental animals. It serves as a model organism for analyzing numerous biological processes and pathological mechanisms, such as cardiovascular diseases, metabolic disorders (e.g., lipid metabolism, diabetes mellitus), neurological and neuropsychiatric conditions (e.g., stroke, epilepsy, or Alzheimer's disease), neurobehavioral research, autoimmune diseases (e.g., arthritis), cancer, and renal diseases. It offers many unique advantages for modeling human diseases, testing drugs and natural substances, and studying responses to environmental factors. The size of the laboratory rat, compared to the mouse, creates ideal conditions for physiological manipulations. Additionally, rats are used in clinical toxicology to test chemical substances (Hedrich, 2000).

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E-publication

Lucia Dimunová-Valéria Parová

The aim of this publication is to provide a comprehensive overview of the theoretical and practical foundations of management and to highlight the specific features of governance within healthcare organizations. It includes chapters on the historical development of management, major concepts, current trends, the specifics of healthcare management, and various models of healthcare delivery. Special attention is devoted to the roles and characteristics of managers, as well as to the five fundamental managerial functions—planning, decision-making, organizing, leading, and controlling. The purpose of the publication is to foster analytical and critical thinking skills in addressing problems within healthcare institutions and to contribute to improving the quality and safety of healthcare through effective management. The text incorporates numerous practical examples and review questions designed to verify knowledge and strengthen the connection between theory and practical skills. This publication is intended for nursing students and other healthcare disciplines, academic staff, and healthcare facility managers.

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