Barevný atlas biochemie

Marek Stupák et al.

Medical Chemistry presents an overview of the most important topics of general, organic and bioinorganic chemistry for students of General and Dental Medicine study programs. Its aim is to provide a theoretical basis for the study of the subject Medical Chemistry and for understanding processes and chemical reactions which are taking place in the human body.

Each topic directly links chemical principles to the processes in living organisms and thus can help the students to clearly see the application of the presented information. Therefore, it also provides a good starting point for further study of Medical Biochemistry, for which the knowledge of these principles is necessary.

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Mária Mareková a kol. 

Medical biochemistry is integral parts of basic theoretic knowledge of contemporary graduate at medical faculties. This textbook intends to help the undergraduate students of study branches General Medicine and Dental Medicine for the course of “Medical Biochemistry”. It is structured into 10 chapters concerning several topics: enzymology, cells membrane, metabolism, biochemistry of blood and organs, as well as some parts of clinical biochemistry.

The theoretical knowledge of this subject, which student obtains in the lectures, is verified in laboratory practices and is expanded in seminaries. Our selection of topics makes the text especially appropriate for medical students and managing of problems gives the students satisfactory ground for effective study of medical biochemistry and other related study subjects (e.g. clinical biochemistry, physiology, pathophysiology) in the sense of comprehension of relative continuity and interdependence of biochemical process or their function respectively.

Since the textbook brings only the skeleton survey on the biochemical problematic concerning medicine, students should broaden presented facts by additional study from lectures and/or from other sources. We expect this study literature to serve as a basic study material for mentioned medical study branches for preparation to written part of exam from “Medical Biochemistry”.

Authors

Jozef Turay

Hlavný rizikový faktor v etiopatogenéze aterosklerózy a jej komplikácií je dyslipoproteinémia. Zmenený metabolizmus lipoproteínov aktivuje obranný systém organizmu, zasahuje do koagulácie a provokuje endoteliálne bunky cievnej steny k zmenenej metabolickej aktivite. Liečba dyslipoproteinémií je jedným zo základných kameňov v primárnej a sekundárnej prevencii koronárnych chorôb, cerebrovaskulárnych chorôb a ochorení periférnych ciev. Statíny ovplyvňujúce dyslipoproteinémie sú treťou najúspešnejšou skupinou liekov po objavení penicilínu a kyseliny acetylosalicylovej (aspirínu)v dejinách farmakoterapie. Ateroskleróza, ktorá postihuje artérie je, multifaktoriálne ochorenie determinované rizikovými faktormi, ktoré v industrializovaných krajinách spúšťajú lavínu šírenia aterosklerotických komplikácií. Preto úprava lipoproteínového spektra je základom prevencie rozvoja aterosklerózy a jej komplikácií.

Táto monografia má byť východiskom zo spleti informácií, ktoré sa dostávajú k lekárovi z elektronických informačných systémov. Má priviesť čitateľa k praktickej aplikácii nových poznatkov z patogenézy, diagnostiky a liečby dyslipoproteinémií, ktoré zohrávajú kľúčovú úlohu v procese rozvoja aterosklerózy, resp. jej regresie.

Kniha je určená širokému spektru lekárov, ale predovšetkým kardiológom, diabetológom, klinickým biochemikom a všeobecným lekárom.

E-book

Gabriel Žoldák

The textbook is intended as background material for university students and for education in science, biotechnology, and medicine. During the textbook conception, the emphasis was on recent trends and development in the understanding of the physicochemical properties of immunoglobulins.

The textbook is divided into ten chapters and 294 pages dealing with the following topics: Immune system and immunoglobulins, General properties of immunoglobulins, Chemical and proteolytic cleavage of immunoglobulins, Structure of immunoglobulins I, Structure of immunoglobulins II, Detection of immunoglobulins, Post-purification and purification immunoglobulin modifications, Immunoglobulin stability and aggregation, Therapeutic immunoglobulins. In addition to the summary of the established knowledge about the properties of immunoglobulins, the textbook also contains new information collected from recent scientific publications.

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