Dyslipoproteinémia a ateroskleróza

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Jozef Turay

Hlavný rizikový faktor v etiopatogenéze aterosklerózy a jej komplikácií je dyslipoproteinémia. Zmenený metabolizmus lipoproteínov aktivuje obranný systém organizmu, zasahuje do koagulácie a provokuje endoteliálne bunky cievnej steny k zmenenej metabolickej aktivite. Liečba dyslipoproteinémií je jedným zo základných kameňov v primárnej a sekundárnej prevencii koronárnych chorôb, cerebrovaskulárnych chorôb a ochorení periférnych ciev. Statíny ovplyvňujúce dyslipoproteinémie sú treťou najúspešnejšou skupinou liekov po objavení penicilínu a kyseliny acetylosalicylovej (aspirínu)v dejinách farmakoterapie. Ateroskleróza, ktorá postihuje artérie je, multifaktoriálne ochorenie determinované rizikovými faktormi, ktoré v industrializovaných krajinách spúšťajú lavínu šírenia aterosklerotických komplikácií. Preto úprava lipoproteínového spektra je základom prevencie rozvoja aterosklerózy a jej komplikácií.

Táto monografia má byť východiskom zo spleti informácií, ktoré sa dostávajú k lekárovi z elektronických informačných systémov. Má priviesť čitateľa k praktickej aplikácii nových poznatkov z patogenézy, diagnostiky a liečby dyslipoproteinémií, ktoré zohrávajú kľúčovú úlohu v procese rozvoja aterosklerózy, resp. jej regresie.

Kniha je určená širokému spektru lekárov, ale predovšetkým kardiológom, diabetológom, klinickým biochemikom a všeobecným lekárom.

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978-80-89797-68-4

Data sheet

Method of publication:
Printed publication
Author:
Jozef Turay
Document type:
Monograph
Number of pages:
112
Year of publication:
2021
Publication language:
Slovak
License:
Copyright

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