Výživa - racionálna výživa človeka

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Peter Berek

With the development of endovascular surgery, there is a gradual advancement in ACI stenting. The minimally invasive approach has made this methodology suitable for patients with serious concomitant cardiac or pulmonary diseases. Another advantage compared to surgical treatment was better access to the ICA in patients after radiotherapy, after previous neck surgeries, as well as in patients with stenoses close to the skull base.

The comparison of CEA vs CAS is an interesting and debatable topic in many studies. However, despite the massive global development of endovascular treatment, carotid endarterectomy remains the gold standard for treating ICA stenosis in both symptomatic and asymptomatic patients. In this monograph, we would like to accentuate and systematize the issue of surgical stroke prevention from the perspective of a vascular surgeon.

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Peter Berek 

S vývojom endovaskulárnej chirurgie dochádza postupne k rozvoju stentingu ACI. Minimálne invazívny prístup spravil túto metodiku vhodnú pre pacientov s vážnymi konkomitatnými kardiálnymi alebo pľúcnymi ochoreniami. Ďalšou výhodou v porovnaní s chirurgickou liečbou bol lepší prístup k ACI u pacientov po rádioterapii, po predchádzajúcich operáciách na krku, ale aj u pacientov so stenózami blízko lebečnej bázy. Porovnanie CEA vs CAS je zaujímavou a diskutabilnou témou mnohých štúdií. Avšak, aj napriek celosvetovému mohutnému rozvoju endovaskulárnej liečby karotická endarterektómia ostáva zlatým štandardom liečby stenózy ACI u symptomatických aj asymptomatických pacientov.

V tejto monografii by sme radi akcentovali a systematizovali problematiku chirurgickej prevencie CMP z pohľadu cievneho chirurga.

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I. R. Mavlyanov - A. K. Ashirmetov - Z. I. Mavlyanov - G. J. Jarilkasinova

Need of carrying out a pharmacological genotyping for providing the individualized pharmacotherapy is shown in the monograph based on the analysis of own and literary data of the central link of drug pharmacokinetics– systems of cytochrome P-450, taking into account its genetic polymorphysm.
The monograph is intended for the clinical pharmacologists, geneticists and experts dealing with this problem.

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Martina Vidová Ugurbas

Plastická chirurgia je vysoko špecializovaný medicínsky odbor, ktorý sa zaoberá korekciou defektov, rekonštrukciou a zdokonaľovaním ľudského tela.

Náplňou plastickej chirurgie je korekcia rôznych defektov, vrodených i získaných. Medzi vrodené chyby patria deformity tváre, rázštepy pery a podnebia, deformity ušnice, vrodené vývojové chyby končatín. Najčastejšie získané defekty sú po poraneniach, po chirurgických výkonoch, po fyzikálnych poškodeniach kože a štruktúr krytých kožou.

Do plastickej chirurgie patrí i estetická chirurgia, onkochirurgia a mikrochirurgia, ktorá si zaslúži osobitnú pozornosť. Novými trendami v estetickej chirurgii je rekonštrukcia pomocou tukového tkaniva, kmeňových buniek, používanie rôznych umelých materiálov a implantátov.

Predložené učebné texty v jednotlivých kapitolách popisujú základné princípy plastickej chirurgie, používanie lalokových plastík a iné možnosti krytia defektov. V ôsmych kapitolách sú jednotlivo popísané chirurgické možnosti rekonštrukcie tváre, trupu a končatín. Učebné texty venujú pozornosť malígnym a benígnym kožným tumorom a ich liečbe. Posledná kapitola sa zaoberá najčastejšími estetickými operáciami ako sú augmentácia a redukcia prsníkov, facelifting či blefaroplastika.

 Eva Ďurovcová - Mária Mareková 

The presented textbook is intended for students of general medicine and should support their knowledge about indication and interpretation of basic biochemical tests. Clinical biochemistry continues to be one of the most rapidly advancing areas of laboratory medicine, which in line with using of modern technology more and more emphasizes the evidence-based medicine in order to improve diagnosis and monitoring of patients. Selected topics have an ambition to outline and explain the most common issues of biochemical diagnosis of in internal medicine. Individual chapters are devoted to disorders of water, electrolyte and acid-base balance, kidney and liver disease, diabetes mellitus, and biomarkers used in the diagnosis of cardiac necrosis and heart failure. Given the limited range, the textbook merely summarizes the basic knowledge that students have obtained during the study of other subjects, such as medical biochemistry, pathophysiology and internal medicine, and emphasis is given to laboratory diagnosis in accordance with the newer guidelines of professional societies. We hope that the textbook will be helpful in the study of clinical subjects and encourage students' interest in laboratory medicine.

Authors

E-book

Andrea Madarasová Gecková - Daniela Husárová   a kol.

National Report on the Health and Health-Related Behaviour of 11-, 13-, and 15-Year-Old Schoolchildren Based on the Survey Conducted in 2021/2022 within the International Project “Health Behaviour in School-aged Children” (HBSC)

For several years, this study has provided us with key insights for a better understanding of the health-related behaviour of our young people. It examines a range of health-related topics such as sleep, mental well-being, nutritional behaviour, and physical activity. Important areas of research also include school and social relationships within it, family and family background, as well as peer relationships.

The findings deepen our understanding of the mechanisms influencing differences and changes in young people’s health and risk behaviours. They are crucial for the development of effective health promotion programmes and health-related behavioural interventions, educational programmes in this field, and for monitoring their effectiveness—not only at the national but also at the international level. The knowledge gained is important for a better understanding of the needs of schoolchildren and for adapting services and systemic support so that these needs are taken into account to the greatest possible extent in today’s rapidly changing world. The study can help us understand the impact of the COVID-19 pandemic on the quality of both mental and physical health.

The pandemic and the related epidemiological and hygiene measures aimed at limiting the spread of the virus have meant significant restrictions in the daily lives of people of all ages—including children and adolescents. The standard educational process, social contact with peers, extracurricular activities, and other interests both in and out of school were severely disrupted, which had a significant impact on the experiences of schoolchildren.

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Peter Berek

University scripts “Visceral pathology of vascular origin“analyze one of the most challenging vascular regions, the aorta and the visceral aortic branches, from the surgical perspective. The diagnostic and the treatment aneurysms of the abdominal aorta are dedicated to the first chapter. Early diagnostic and operative treatment is crucial in the treatment of ruptured aneurysms of the abdominal aorta. Shortening of the interval between the patient’s arrival with ruptured aneurysm of the abdominal aorta into the hospital and the beginning of the operation decreased the perioperative mortality. This shortening, together with the use of the cell savers, led to the dropping of perioperative mortality from 50% to 20%. The diagnostics and surgical treatment of the acute and chronic occlusion of the aorta and iliac arteries are analyzed in the second chapter. In this chapter, the focus is given to the aortobifemoral bypass as “the gold standard“ of the surgical therapy of aortoiliac atherosclerosis. The management of acute mesenteric ischemia is the content of the third chapter. Acute mesenteric ischemia is a severe condition with high mortality. The problem of acute mesenterial ischemia is a delayed diagnostic that is the reason for poor therapeutical outcomes of the disease. The possible imagine studies and operations used in treating acute mesenteric ischemia are brought in this chapter. Chronic mesenteric ischemia leads to cachexia. The diagnosis of chronic mesenterial ischemia is one of the most demanding, and surgical therapy used in the treatment of chronic mesenterial ischemia also belongs to the most challenging operations. Left-sided colon ischemia belongs to the severe complications of the aortoiliac reconstructions. Left-sided colon ischemia has a high mortality. In the prevention of the left-sided colon, ischemia is preserving at least one internal iliac artery. The complex diagnostics treatment of intraabdominal compressive syndromes as Dunbar syndróme, „Nutcracker“ syndróme a Wilkie syndróme, analyzed in the last chapter.

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Ladislav Kočan-Dušan Rybár-Róbert Rapčan

The autonomic nervous system is a vital component of the peripheral nervous system, responsible for maintaining homeostasis and regulating internal processes within the body. Unlike the voluntary control exerted by the central nervous system, the autonomic nervous system operates involuntarily, innervating smooth organs, vessels, skin glands, and even exerting some influence over skeletal muscles in connection with vegetative functions such as breathing, digestion, and the urinary and gonadal systems. Its impact extends crucially to the cardiac muscles of the heart and plays a significant role in endocrine and metabolic functions, thermoregulation, as well as emotional and behavioral responses, including adaptive reactions to stressors. The aim of this publication is to provide a comprehensive and objective exploration of the anatomical and physiological intricacies of the autonomic nervous system, offering insights into its clinical applications. Within these pages, we meticulously delineate various interventional therapeutic procedures tailored to specific diagnoses related to the autonomic nervous system, aligning each intervention with the anatomical framework of the autonomic system. The efficacy of these procedures is evaluated based on the level of evidence, as per the current recommendations of Evidence-Based Medicine. This publication is primarily crafted for fifth and sixth-year medical students and medical professionals specializing in anesthesiology, intensive care, and pain medicine. It serves as a valuable resource for gaining a deeper understanding of autonomic nervous system function and its clinical implications, facilitating informed decision-making in clinical practice.

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Jana Diabelková

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Ján Kučera - Eva Kovaľová - Juraj Strecha

Peri-implantation diseases such as peri-implantitis and mucositis have a wide range of prevalence. Several etiological factors and the interaction of risk factors influence their onset and development. Careful investigation determines the diagnosis and subsequent treatment. Treatment, depending on the condition, is either non-surgical or surgical. Systematic postoperative care, a recall system, and patient instruction and cooperation are essential, which create the preconditions for successful implant treatment.

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Martina Zavacká a kolektív

Kniha „DIABETICKÁ NOHA Z POHĽADU CIEVNEHO CHIRURGA“ obsahuje 14 kapitol. Pojednáva o syndróme diabetickej nohy z multidisciplinárneho pohľadu viacerých odborníkov: angiochirurga, diabetológa, chirurga, podiatra, röntgenológa, neurológa a algeziológa. Úvodné kapitoly majú charakter propedeutiky, čo má taktiež význam aj pre pregraduálnu výchovu. Nasledujúce kapitoly sa zaoberajú vznikom syndrómu, výskytom, jeho diagnostikou, terapeutickými postupmi, pridruženými postihnutiami neurologického charakteru, starostlivosťou podiatra a algeziológa pri pretrvávaní bolestí. Ďalšie časti sú vyhradené chirurgickej a endovaskulárnej liečbe tepien cestou cievneho chirurga a intervenčných angiológov. Nezabúdajúc na problematiku amputácií a správnu rehabilitáciu pacientov s diabetom.  V knihe nájdu poučenie cievni chirurgovia, angiológovia, všeobecní chirurgovia, diabetológovia, neurológia, röntgenológovia, podiatri  a všeobecní lekári.

Kniha je zdrojom najnovších teoretických i praktických informácií pre postgraduálnu výchovu vyššie spomenutých odborníkov.

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E-book

Tatiana Kimáková - Vladimír Pavlík

The scientific monograph focuses on the characteristics of free radicals, reactive oxygen and nitrogen species, oxidative stress, and its impact on various diseases. A significant portion is dedicated to antioxidants, their classification based on multiple criteria, the characteristics of selected antioxidants in terms of their functions, manifestations of their deficiency and excess, and the overall antioxidant capacity of the body.

A special section is devoted to enzyme-based antioxidants, natural sources of antioxidants in the form of vitamins, trace elements, flavonoids, polyphenols, and coenzyme Q10. To provide a clearer understanding of antioxidants and their influence on population health, the monograph presents results from a research project included in the program "Research Support for Enhancing the Defense Capabilities of the Czech Republic in NATO Structures."

The research was conducted between 2010 and 2012 as part of preventive rehabilitation programs for professional soldiers with a sports component. The study involved 218 professional soldiers, including 180 men and 38 women, with an average age of 33.3 years. The current health status and dietary habits of the soldiers were assessed using questionnaires.

The study described the saturation of the observed group with antioxidant vitamins and statistically evaluated the relationship between their levels and the risk indicators for the development of cardiovascular diseases. Individual analyses were performed using the Reflotron device calibrated with Reflotron Precinorm control serum. Following blood collection, all participants underwent anthropometric examinations (body weight, height, waist circumference), blood pressure measurements, heart rate monitoring, and physical fitness assessments through simple functional tests.

This scientific monograph is suitable for the scientific community, students of medical, veterinary, and natural sciences, as well as public health students at all levels of university education. It is also intended for informed members of the public.

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Pavol Pobeha - Ivana Paraničová - Pavol Joppa

The publication "Respiratory Medicine and Tuberculosis—Selected Chapters" is an anticipated study material intended for medical students at medical faculties and can also serve as supplementary literature in the framework of postgraduate education for specialist doctors. By compiling chapters and content, it builds upon the Slovak version of the publication "Selected Chapters from Pneumology and Phthisiology" (edited by Pavol Joppa), but the new publication expands pneumology with additional nosological units and issues in the context of current evidence-based medicine.

This book adds topics such as Sleep Breathing Disorders and Respiratory Failure to standard pneumology topics like asthma, chronic obstructive pulmonary disease, lung cancer, pneumonia, interstitial diseases, and tuberculosis. These topics are often mentioned only marginally in pneumological publications and within internal diseases. A significant contribution is the comprehensively processed chapter on Cor pulmonale chronicum, which connects several clinical fields including pneumology, internal medicine, and cardiology. We believe that the prepared publication will find favor among readers and will be beneficial in educating students and practitioners.

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E-publication

Miriam Kozárová

Simulation-based medical education has become an integral part of medical education in the 21st century. It represents a modern and effective way to enable medical, nursing, emergency medicine, and other healthcare team members to safely develop clinical skills, decision-making abilities, and teamwork. Simulation-based medical education (SBME) is primarily about opportunities to try out and experience medical/nursing/rescue procedures in a safe environment without any risk to real patients.

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Dorota Sopková - Silvia Farkašová Iannaccone

Forensic medicine is a medical discipline that is concerned with the determination of the cause of death in cases of violent and non-violent deaths, as well as the assessment of the effects of violence on the human body, including in cases of living persons. The presented textbook provides a consolidated and comprehensive review of the basic tasks and theoretical knowledge of the field of forensic medicine. Its goal is to provide a theoretical basis for the study of the compulsory subject Forensic Medicine and Medical Law in the study programs General Medicine and Dental Medicine, which has been absent until now. The authors emphasize the need to know the basics of forensic medicine in every medical field and a multidisciplinary approach to solving medico-legal questions.

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Alžbeta Blichárová a kolektív

“Pathology Part 1 (winter semester) - Practical lessons for students of dental medicine” represents the first half of the university textbook designed for the pregradual study of pathology. The textbook complements the lectures of pathology and serves as a source of information for students of dental medicine, that are preparing for the practical as well as the final oral examination.

In this part of the “Pathology” series, fifty-four selected histopathological slides are presented. Each selected slide is provided with general information in relation to etiology and pathogenesis of the disease, as well as with corresponding morphological features, including the gross appearance and the most important histopathological characteristics. The textbook summarizes the basic concepts of general pathology that are necessary to master the broad field of systemic pathology in the second semester.