Slovenčina
Primary Cholestatic Liver Diseases
E-book
The Lecture Notes Primary Cholestatic Liver Diseases is intended primarily for undergraduate medical students and provides a comprehensive and up-to-date overview of the diagnosis and management of the major cholestatic liver diseases. The publication focuses primarily on primary biliary cholangitis (PBC) and primary sclerosing cholangitis (PSC). The introductory section covers the physiology of bile formation and transport, the pathophysiological mechanisms underlying cholestasis, and the fundamental diagnostic approach to patients presenting with a cholestatic pattern of liver test abnormalities.
The individual chapters integrate current knowledge of disease pathogenesis and natural history with a practical, clinically oriented approach to patient care. Particular emphasis is placed on the interpretation of laboratory, immunological, imaging, and histological findings; non-invasive assessment of liver fibrosis; risk stratification for disease progression; current therapeutic options; and indications for liver transplantation.