Patofyziológia pre zdravotnícke odbory

Mária Mareková a kol. 

Medical biochemistry is integral parts of basic theoretic knowledge of contemporary graduate at medical faculties. This textbook intends to help the undergraduate students of study branches General Medicine and Dental Medicine for the course of “Medical Biochemistry”. It is structured into 10 chapters concerning several topics: enzymology, cells membrane, metabolism, biochemistry of blood and organs, as well as some parts of clinical biochemistry.

The theoretical knowledge of this subject, which student obtains in the lectures, is verified in laboratory practices and is expanded in seminaries. Our selection of topics makes the text especially appropriate for medical students and managing of problems gives the students satisfactory ground for effective study of medical biochemistry and other related study subjects (e.g. clinical biochemistry, physiology, pathophysiology) in the sense of comprehension of relative continuity and interdependence of biochemical process or their function respectively.

Since the textbook brings only the skeleton survey on the biochemical problematic concerning medicine, students should broaden presented facts by additional study from lectures and/or from other sources. We expect this study literature to serve as a basic study material for mentioned medical study branches for preparation to written part of exam from “Medical Biochemistry”.

Authors

E-kniha

Steven J. Luck

Preklad: Július Zimmermann a Eva Kiktová

Kniha je slovenským prekladom anglickej monografie Stevena J. Lucka An Introduction to Event-Related Potential Technique (2014). Technika potenciálov, ktoré súvisia s udalosťami (ERP), je neinvazívny spôsob skúmania procesov percepcie a kognície ľudského mozgu. Subjekty – skúmané osoby, vnímajú špeciálne navrhnuté formy vizuálnych alebo rečových stimulov. Zo snímanej sústavy EEG signálov sa matematickými metódami extrahujú osobitné ERP signály, pričom sú u nich zaujímavé tri typy rozlišovacích schopností: časové rozlíšenie (latencia), amplitúdové rozlíšenie (magnitúda) a priestorové rozlíšenie (oblasť mozgu), v ktorej sa generujú ERP signály. Latencia a magnitúda signálov sú v tejto metóde unikátne parametre prezentujúce uvedené procesy, priestorové rozlíšenie je v tomto prípade menej dokonalé.

V knihe je výklad celého experimentálneho ERP výskumu: návrh a prevádzka laboratória, dizajn experimentov, akvizícia EEG signálov a korekcia šumov a artefaktov. Nasleduje detekcia ERP signálov: filtrovanie a Fourierova analýza, kvantifikácia amplitúd a latencií, osobitné metódy v časovej aj frekvenčnej doméne a podobne. Nakoniec štatistickou analýzou a interpretačnými metódami sa formulujú dosiahnuté výsledky výskumu. Pre čitateľa sú cenné aj poznatky v kapitole o tom, ako sa píšu štúdie s dobrým kreditným ohodnotením a ako sa takéto štúdie oponujú.

Kniha je cenným zdrojom pre výskumných pracovníkov, pre doktorandov a postdoktorandov, ale aj pre študentov, ktorých zaujala nesmierne zložitá a málo preskúmaná činnosť ľudského mozgu.

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Ondrej Hutník

The concept of the integral is one of the most significant concepts in mathematics as a whole. In its most primitive form, it was already used by the ancient Greeks in the creation of Euclidean geometry. However, it was only after Descartes' work on analytical geometry in 1637 that mathematicians could begin to consider the integral as a subject of analysis. Descartes' work laid the groundwork for the discovery of infinitesimal calculus by Leibniz and Newton around 1665. At that time, a great dispute arose over the priority of this discovery, dividing scholars of Germany and England into two opposing camps, each favoring their own champion. Today, we know that Newton's work on fluxions and fluents was somewhat earlier, but Leibniz's notation and approach have gained more acceptance in the mathematical world, and the symbols ∫ ∫ and d d are still used today. A brief overview of the history of the integral will be presented in Chapter 1.

Today, there is a plethora of scripts, textbooks, and books dedicated to explaining the concept of the integral. Therefore, every potential author faces the initial question of whether to write another text on this topic. Our affirmative answer to this question was driven by the students' request to find the subject matter of a part of the winter semester of the second year presented in a coherent form. The second motivation is a slightly different approach to the topic. If we consider the methods typically used in solving problems and gaining routine with a certain integral, it mainly involves the Newton-Leibniz formula, and often there is little time left to compute the definite (Riemann) integral using its definition. Therefore, we included a discussion of the Newton integral in Chapter 2, which reflects this fact and is directly related to the indefinite integral, whose various calculation methods receive relatively much attention in the previous semester. Only after that, in Chapter 3, do we build the theory of the Riemann integral, present criteria for its existence, classes of integrable functions, basic properties, and finally its relationship with the Newton integral. Questions primarily concerning geometric applications are addressed in Chapter 4, and in the final chapter, we focus on extending the Riemann integral to unbounded functions and unbounded intervals.

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Alena Krunková (ed.)

Proceedings of the Scientific Conference Held on June 28, 2016 at the Faculty of Law of Pavol Jozef Šafárik University in Košice in connection with the implementation of the project “The European Union and Its Impact on the Organization and Functioning of Public Administration in the Slovak Republic” – approved under number MVZP – SK PRES/2016/134

The Slovak Republic, as a member state of the European Union, is undertaking a historic role associated with the Presidency of the Council of the European Union within the presidency trio. At the beginning of 2016, the Ministry of Foreign and European Affairs of the Slovak Republic announced a call for applications for grants for 2016 in the field of international relations and foreign policy, specifically focused on the Slovak Republic’s Presidency of the Council of the European Union. The Faculty of Law of Pavol Jozef Šafárik University in Košice responded to this call and obtained a project aimed at carrying out research activities through a series of events focused on regional self-government in the Slovak Republic in the context of its role within the European Union. The Faculty has long been engaged with issues of European Union law both in its teaching and in the scientific research activities of its individual faculty members. The project aims to enrich this portfolio with special activities targeting not only professionals, but also students and the general public.

The first activity of the project was a conference entitled “The European Union and Its Impact on the Organization and Functioning of Public Administration in the Slovak Republic – Development So Far, Current State, and Perspectives.” The conference was attended by invited public officials, representatives of academia, and representatives of local government, as one of the main goals of the project is to connect the academic community with the practical sphere and thus involve practitioners in the planned activities within the project.

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Dušan Šlosár - Vladimír Lichner

This university textbook aims to provide readers with knowledge of the philosophical foundations, meaning, and purpose of mediation, based on research and analysis of mediators' activities. In countries where mediation services operate, their staff often include graduates of social work departments.

An individual approach to both the perpetrator and victim of a criminal offense requires knowledge and skills from social work, psychology, sociology, communication, and related fields tied to social work. The principles of social work apply not only in social policy and social care but also in justice. A mediator’s mission is to facilitate alternative resolutions to unlawful acts while preserving the purpose of legal proceedings as defined by valid legal norms. They fulfill this mission through specific methods of individual social work applied in the justice sector. The mediator’s focus extends beyond the current conflict to uncover related issues, activate parties to resolve disputes, and prevent new conflicts.

Special attention is devoted to the philosophical foundations of mediation in Slovakia. We provide an overview of mediators’ core activities and mediation types used to uphold justice in Slovakia. We analyze mediation goals, the roles of parties involved, and procedural steps. In applying mediation, we explore its potential and implementation in both legal and social work contexts.

As indicated, mediation cannot be understood solely as a specialized activity in criminal justice, as it has broader applications in non-judicial dispute resolution, such as family or community work, which are often overlooked by the public. The mediator’s approach to diverse target groups is grounded in theoretical frameworks. From this foundation, we derive activities expected of mediators in the future. Expanded activities arise from concrete situations encountered during mediation.

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Elena Lazoríková - Adrián Popovič - Anna Románová

Reviewed proceedings of scientific papers

The Proceedings presents papers from international scientific conference “The Condition of Public Finances in the EU and their Future Perspectives” held on June 2 – 3, 2022 in Košice, Slovakia and is published as a partial outcome of the implementation of the VEGA project No. 1/0485/21: "Simultaneity and possibilities of reforming the system of own resources of the EU budget (legal and economic aspects also in the context of the consequences of the COVID-19 pandemic)" and VEGA project No. 1/0214/21: "Real Property Tax - Legal Status and Potential".

The proceedings consist of contributions from conference participants divided into two thematic sections: “The EU Budget” and “Real Estate in Taxation.” While the first section addresses both the revenue side of the EU budget (particularly in the context of the own resources system), as well as its expenditure side and its relationship to other budgets, the second section focuses on real estate as the subject of specific regulations under various taxes, including those that directly tax real estate through a tax of the same name.

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Jana Balegová

University textbook Lingua Latina – Exercise Book for Historians is a parallel study material to the textbook Lingua Latina – Cursus Communis. It is designed for practicing grammar at home. The content of the exercises corresponds to the focus of the individual lessons in the mentioned textbook, both in terms of the covered grammatical phenomena and vocabulary. For this reason, only vocabulary not covered in the textbook's lessons is included in the exercises.

The Latin-Slovak dictionary at the end of the exercise book contains all the vocabulary from both the exercise book and the textbook. The Slovak-Latin dictionary includes the vocabulary from exercises that require translation into Latin. The vocabulary in this exercise book is oriented towards the needs of history students and, given the selection of source materials, also includes non-classical lexicon or non-classical meanings of classical words (this lexicon is marked with the symbol *).

The exercise book includes a key that allows students to directly verify the correctness of their work. The textbook Lingua Latina – Exercise Book for Historians is available electronically in PDF format. As part of the teaching program, online tests available on the KKF FF UPJŠ website (https://www.upjs.sk/filozoficka-fakulta/katedra-klasickejfilologie/katedra/) also serve to practice the covered material.

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Pavol Joppa a kol.

University textbooks address the etiopathogenesis, clinical presentation, diagnosis, differential diagnosis, treatment, complications, and prognosis of the most significant non-specific respiratory diseases, including bronchial asthma, chronic obstructive pulmonary disease (COPD), pneumonias, pleural syndrome, lung cancer, interstitial lung diseases (including exogenous allergic alveolitis and sarcoidosis), and sleep apnea syndrome.

The final section on non-specific diseases discusses chronic cor pulmonale as the primary cardiovascular complication of chronic pulmonary diseases.

The last chapter focuses on the etiopathogenesis, diagnosis, treatment, and prevention of pulmonary and extrapulmonary forms of tuberculosis, addressing the scope of phthisiology

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Ľudmila Pošiváková -  Zuzana Antošová - Milan Kočan (eds.)

Proceedings from the Student Debate held on April 24, 2013, at the Faculty of Law of Pavol Jozef Šafárik University in Košice.

In the current period, the rule of law is widely debated both at the academic and political levels. This debate is not only related to the effort to establish the Rule of Law in states that have transitioned from socialist to democratic systems but also in states experiencing various unrests, whether political or religious.

However, it is not just a debate about certain characteristics of the Rule of Law that are missing in domestic law or at the level of international law, but also a debate about the very definition and meaning of the Rule of Law. The rule of law can be likened to an ideal that almost every state strives to achieve. Even in the case of the establishment of the independent Slovak Republic, the framers decided to include among the introductory provisions, which should form the core of the constitution, that the Slovak Republic is a state governed by the rule of law.

However, to achieve the ideal of the rule of law, it is necessary not only to declare it but also to adopt measures essential for an independent judiciary, democracy, the effective enforcement of human rights, the separation of powers, and many other elements that characterize a state governed by the rule of law.

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Terézia Kisková - Stanislav Matéffy - Františka Horváthová

The laboratory rat (Rattus norvegicus) is one of the most commonly used experimental animals. It serves as a model organism for analyzing numerous biological processes and pathological mechanisms, such as cardiovascular diseases, metabolic disorders (e.g., lipid metabolism, diabetes mellitus), neurological and neuropsychiatric conditions (e.g., stroke, epilepsy, or Alzheimer's disease), neurobehavioral research, autoimmune diseases (e.g., arthritis), cancer, and renal diseases. It offers many unique advantages for modeling human diseases, testing drugs and natural substances, and studying responses to environmental factors. The size of the laboratory rat, compared to the mouse, creates ideal conditions for physiological manipulations. Additionally, rats are used in clinical toxicology to test chemical substances (Hedrich, 2000).

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Ján Junger - Andrea Junger

Vysokoškolské učebné texty Úvod do športu a rekreácie sú určené študentom prvého ročníka v študijnom programe Šport a rekreácia. Svojim zameraním ponúkajú študentom základné informácie o orientácii daného študijného programu. Obsahom sú základné pojmy a tvorba termínov, systém vied o športe a jeho okolie, podstata a miesto športu a rekreácie v systéme spoločenských javov, šport ako špecifický druh pohybovej aktivity človeka, materiálne, ekonomické a organizačné zabezpečenie športu doma a v zahraničí a význam športu v medzinárodnom kontexte.

Eva Slabá - Jozef Židzik a kolektív

Vysokoškolská učebnica „Lekárska biológia a genetika“ poskytuje v zrozumiteľnej podobe teoretické základy bunkovej biológie, molekulovej biológie a genetiky. Obsahuje najnovšie poznatky z relevantných odborov doplnené názornými obrázkami, tabuľkami a grafmi. Prehľadne členené kapitoly zoznámia študentov s problematikou bunkovej biológie, procesov molekulovej biológie a zákonitosťami genetiky. Vysokoškolská učebnica je určená predovšetkým pre slovenských študentov I. ročníka lekárskych fakúlt. Jej obsah je podkladom pre úspešné zvládnutie obsahovej náplne predmetu biológia. Učebnica je vhodná aj ako hlavný zdroj informácií pre študentov prírodovedeckých fakúlt. Okrem základných údajov obsahujú niektoré kapitoly aj doplňujúce informácie pre lepšie pochopenie jednotlivých tematických okruhov. Tieto podrobnejšie údaje sú odlíšené veľkosťou písma a nie sú nevyhnutné pre zvládnutie skúšky z biológie. Príslušné informácie však môžu využiť i študenti vyšších ročníkov lekárskych fakúlt či študenti postgraduálneho štúdia.

E-book

Vladimíra Timková a kol.

Slovakia has one of the highest mortality rates from preventable and treatable causes. The latest data also shows that within the EU, we have the highest mortality rate from cancer. A person's health is influenced by a combination of genetics, different life circumstances, and personal decisions. While we do not have control over all of these factors, proper eating habits, regular physical activity, and quality sleep can significantly contribute to preventing health problems and chronic diseases. However, many people face barriers such as financial constraints, work overload, or a lack of reliable information and knowledge. In Slovakia, almost half of the population cannot afford to purchase nutritious food, which makes the situation even more difficult. Therefore, we have prepared a practical guide with simple, affordable, and time-efficient recommendations aimed at improving health and quality of life. The publication provides an overview of the latest research and expert recommendations related to healthy eating, sleep hygiene, physical activity, mental health improvement, building resilience and healthy relationships, and also includes important advice on how to increase motivation for health behaviour change.

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Lukáš Šutor (ed.)

The current sixth volume of the Doctoral Miscellanea consists of eight contributions from four study programs, with two contributions also involving authors outside of doctoral studies. Given the limitations on the length of individual contributions and the uniqueness of the research, the authors have chosen varying widths and depths in presenting their dissertation topics. Some contributions serve as an introduction to the issues, others provide a summary of previous results, and still others focus on a detailed analysis of a specific problem. These three approaches may not only reveal the stage of research in which the doctoral candidate finds themselves but also their potential research priorities.

The main commonality across all issues of the proceedings remains interdisciplinary diversity, which shows a certain continuity. Specific themes appear regularly. In these cases, alongside alternating doctoral candidates, the key figure is the supervisor (in the role of co-author) and their research focus/project in which the doctoral candidates participate. This development of research continuity is particularly evident in contributions from the field of social work.

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Adam Giertl - Ľudmila Elbert

Collection of Papers from the 8th Student Symposium held on April 20–21, 2015 in Danišovce

The capture of the historic Syrian city of Palmyra by fighters of the radical Islamic State caused shock among the global public. The main reason is the barbarism with which this organization proceeds, not only in relation to the treasures of the world’s cultural heritage. The situation in the Middle East, where cultural treasures of inestimable value are under direct threat, demonstrates how fragile the world’s cultural heritage is. The reaction of the international public and world leaders shows how sensitively the destruction of cultural heritage is perceived.

The quoted statement chosen by the editors relates to the threat posed by the Islamic State—however, the spirit of this statement can be applied to any cultural wealth that forms part of the world’s cultural heritage. The destruction or damage of these values primarily represents a loss for humanity as such. Each destroyed artifact of world cultural heritage signifies the disappearance of a unique legacy left by previous generations for the future. At the same time, cultural heritage must be understood as a broad spectrum of assets—both tangible and intangible. Their legal protection was the topic of this year’s symposium. As with any social interest, the protection of cultural heritage can be ensured through various mechanisms and under different forms of social organization.

These diverse approaches are unified by law as a normative system. The question for the 8th year of the symposium on international law was what role international law plays in the protection of cultural heritage. In the context of the European region, the role of the European Union as a regional organization was examined.

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Mária Vilková - Monika Garberová - Michal Goga

Nuclear Magnetic Resonance (NMR) is currently a widely used analytical tool that finds application in many fields of science and technology. The broadening of its practical use brings with it the necessity to create educational texts appropriate to the given scientific discipline.

This university textbook is intended for students of biology and serves as a supplement to the study materials for the advanced master's course "Biology of Lichens." At the same time, it represents a useful resource for master's and doctoral students involved in research, helping them interpret NMR spectra and present basic theoretical concepts.

The textbook briefly describes the important aspects of each NMR spectroscopic technique without delving excessively into the physical principles of individual methods or complex mathematical analyses. In this edition, the structures of lichen metabolites have been included, which students will isolate, purify, and identify using various analytical methods during practical exercises. An entire chapter is dedicated to a detailed description of solving the NMR spectra of isolated metabolites, with each step in elucidating the structures of both known and unknown metabolites explained in detail. The solved tasks are followed by numerous unsolved examples, including high-resolution 1D and 2D NMR spectra of metabolites, intended to further develop the acquired knowledge and skills of students and doctoral candidates in structure elucidation using NMR spectroscopy.

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